ES2245995T3 - Pares de colorantes para mediciones de transferencia de energia de fluorescencia-resonancia (fret). - Google Patents

Pares de colorantes para mediciones de transferencia de energia de fluorescencia-resonancia (fret).

Info

Publication number
ES2245995T3
ES2245995T3 ES01996741T ES01996741T ES2245995T3 ES 2245995 T3 ES2245995 T3 ES 2245995T3 ES 01996741 T ES01996741 T ES 01996741T ES 01996741 T ES01996741 T ES 01996741T ES 2245995 T3 ES2245995 T3 ES 2245995T3
Authority
ES
Spain
Prior art keywords
molecular weight
fluorescence
fret
energy
marked
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES01996741T
Other languages
English (en)
Spanish (es)
Inventor
Daniel Belik
Hans-Dieter Josel
Rupert Herrmann
Bernhard Koenig
Francis Mueller
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
F Hoffmann La Roche AG
Original Assignee
F Hoffmann La Roche AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by F Hoffmann La Roche AG filed Critical F Hoffmann La Roche AG
Application granted granted Critical
Publication of ES2245995T3 publication Critical patent/ES2245995T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
    • G01N33/582—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with fluorescent label
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/536—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase
    • G01N33/542—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase with steric inhibition or signal modification, e.g. fluorescent quenching
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/14—Heterocyclic carbon compound [i.e., O, S, N, Se, Te, as only ring hetero atom]
    • Y10T436/142222—Hetero-O [e.g., ascorbic acid, etc.]
    • Y10T436/143333—Saccharide [e.g., DNA, etc.]

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Cell Biology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
ES01996741T 2000-11-16 2001-11-14 Pares de colorantes para mediciones de transferencia de energia de fluorescencia-resonancia (fret). Expired - Lifetime ES2245995T3 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP00124995 2000-11-16
EP00124995 2000-11-16

Publications (1)

Publication Number Publication Date
ES2245995T3 true ES2245995T3 (es) 2006-02-01

Family

ID=8170391

Family Applications (1)

Application Number Title Priority Date Filing Date
ES01996741T Expired - Lifetime ES2245995T3 (es) 2000-11-16 2001-11-14 Pares de colorantes para mediciones de transferencia de energia de fluorescencia-resonancia (fret).

Country Status (9)

Country Link
US (1) US6908769B2 (https=)
EP (1) EP1337851B1 (https=)
JP (1) JP3905838B2 (https=)
AT (1) ATE300050T1 (https=)
AU (1) AU2002221848A1 (https=)
CA (1) CA2426479C (https=)
DE (1) DE50106822D1 (https=)
ES (1) ES2245995T3 (https=)
WO (1) WO2002041001A1 (https=)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE518913T1 (de) * 2000-09-06 2011-08-15 Evotec Ag Verfahren zur gezielten markierung mittels affinitätsmarkierter detektionsmarker
US20040053399A1 (en) * 2002-07-17 2004-03-18 Rudolf Gilmanshin Methods and compositions for analyzing polymers using chimeric tags
GB2421412B (en) * 2003-02-26 2007-08-29 Tomtom Bv Navigation device with touch screen
BRPI0413703A (pt) * 2003-08-18 2006-10-17 Novartis Ag derivados de 3h-fenoxazina adequados como agentes formadores de imagem do infravermelho próximo, preparação e uso dos mesmos
DE602004015629D1 (de) * 2003-10-01 2008-09-18 Wallac Oy Ansfertest
US8105849B2 (en) * 2004-02-27 2012-01-31 Board Of Regents, The University Of Texas System Integration of fluids and reagents into self-contained cartridges containing sensor elements
WO2005089524A2 (en) * 2004-03-19 2005-09-29 U.S. Genomics, Inc. Compositions and methods for detection of single molecules
US8883486B2 (en) 2004-05-04 2014-11-11 Universite De Montreal Arrestin biosensor
CN100473988C (zh) * 2004-07-08 2009-04-01 厦门大学 具有荧光共振能量转移特点的蛋白组合及其用途
US20090298196A1 (en) * 2005-01-28 2009-12-03 Uwabe Ken-Ichiro Quantitative measurement method for recombinant protein
WO2006125855A1 (en) * 2005-05-24 2006-11-30 Hidex Oy Correction method and measurement device for anti-stokes photoluminescence measurement
WO2007016975A1 (en) 2005-07-29 2007-02-15 F. Hoffmann-La Roche Ag Kinase and phosphatase assays based on fret
FR2890174B1 (fr) * 2005-08-30 2009-04-24 Cis Bio Internat Sa Procede pour la mise en evidence d'un processus biologique par mesure d'un fret
US20100035247A1 (en) * 2005-11-04 2010-02-11 U.S. Genomics, Inc. Heterogeneous Assay of Analytes in Solution Using Polymers
US8178360B2 (en) 2006-05-18 2012-05-15 Illumina Cambridge Limited Dye compounds and the use of their labelled conjugates
US9006283B2 (en) 2007-07-12 2015-04-14 Acumen Pharmaceuticals, Inc. Methods of modifying amyloid β oligomers using non-peptidic compounds
WO2009009127A2 (en) * 2007-07-12 2009-01-15 U.S. Genomics, Inc. Method and system for transferring and/or concentrating a sample
US8962677B2 (en) * 2007-07-12 2015-02-24 Acumen Pharmaceuticals, Inc. Methods of restoring cognitive ability using non-peptidic compounds
US20110098309A1 (en) * 2007-07-12 2011-04-28 Acumen Pharmaceuticals, Inc. Methods of inhibiting the formation of amyloid-beta diffusable ligands using acylhydrazide compounds
WO2009079566A2 (en) 2007-12-18 2009-06-25 Acumen Pharmaceuticals, Inc. Novel addl receptor polypeptides, polynucleotides and host cells for recombinant production
WO2010117420A2 (en) 2009-03-30 2010-10-14 Pacific Biosciences Of California, Inc. Fret-labeled compounds and uses therefor
CA2759885A1 (fr) * 2009-04-30 2010-11-04 Etienne Doumazane Procede de detection de composes modulateurs de dimeres de proteines membranaires a domaine vft
WO2012037361A2 (en) 2010-09-15 2012-03-22 Endacea, Inc. Methods of use and kit for measurement of lipopolysaccharide with a time resolved fluorescence based assay
EP2619316B1 (en) 2010-09-23 2016-12-07 Woundchek Laboratories B.V. Ultrasensitive detection of beta hemolytic streptococcus
US8569254B2 (en) 2010-12-10 2013-10-29 National Yang Ming University Methods for modulating the expression and aggregation of CAG-expanded gene product in cells and methods for identifying agents useful for doing the same
GB201714748D0 (en) * 2017-09-13 2017-10-25 Univ Oxford Innovation Ltd Single-molecule phenotyping and sequencing of nucleic acid molecules
CN109752552A (zh) * 2017-11-05 2019-05-14 江苏维赛科技生物发展有限公司 检测联苯的时间分辨荧光免疫试剂盒及其检测方法
WO2019212946A1 (en) 2018-04-30 2019-11-07 Ribon Therapeutics Inc. Screening methods for parp modulators
KR102267067B1 (ko) * 2020-01-16 2021-06-21 경희대학교 산학협력단 다이에틸싸이아노포스포네이트 검출용 형광 프로브 화합물 및 이의 용도

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0076695B1 (en) 1981-10-06 1985-02-20 The Board Of Trustees Of The Leland Stanford Junior University Fluorescent conjugates for analysis of molecules and cells
US4822733A (en) * 1985-05-28 1989-04-18 Amoco Corporation Lifetime-resolved assay procedures
DE4137934A1 (de) 1991-11-18 1993-05-19 Boehringer Mannheim Gmbh Neue pentacyklische verbindungen und ihre verwendung als absorptions- oder fluoreszenzfarbstoffe
US5246867A (en) * 1992-01-17 1993-09-21 University Of Maryland At Baltimore Determination and quantification of saccharides by luminescence lifetimes and energy transfer
US5622821A (en) * 1994-06-29 1997-04-22 The Regents Of The University Of California Luminescent lanthanide chelates and methods of use
EP1033411B1 (en) * 1996-06-04 2006-02-22 University of Utah Research Foundation Fluorescent donor-acceptor pair
WO1998043072A1 (en) * 1997-03-25 1998-10-01 Photonic Research Systems Limited Luminescence assays
AU3487499A (en) * 1998-04-08 1999-10-25 Regents Of The University Of California, The Methods and reagents for targeting organic compounds to selected cellular locations
GB9811483D0 (en) * 1998-05-29 1998-07-29 Photonic Research Systems Limi Luminescence assay using cyclical excitation wavelength sequence
US5998146A (en) * 1998-07-17 1999-12-07 Wallac Oy Homogeneous luminescence assay method based on energy transfer
WO2000047693A1 (en) * 1999-02-12 2000-08-17 Ljl Biosystems, Inc. Luminescent metal-ligand complexes

Also Published As

Publication number Publication date
US6908769B2 (en) 2005-06-21
JP3905838B2 (ja) 2007-04-18
EP1337851B1 (de) 2005-07-20
CA2426479A1 (en) 2003-04-22
DE50106822D1 (de) 2005-08-25
CA2426479C (en) 2007-08-07
US20040076979A1 (en) 2004-04-22
EP1337851A1 (de) 2003-08-27
WO2002041001A1 (de) 2002-05-23
ATE300050T1 (de) 2005-08-15
JP2004514139A (ja) 2004-05-13
AU2002221848A1 (en) 2002-05-27

Similar Documents

Publication Publication Date Title
ES2245995T3 (es) Pares de colorantes para mediciones de transferencia de energia de fluorescencia-resonancia (fret).
EP0876428B1 (en) SULFO BENZ e]INDOCYANINE FLUORESCENT DYES
CN103308489B (zh) 利用时间分辨上转换发光技术的侧向流动免疫测定法
CN108391432B (zh) 杂环化合物的生物偶联分子
EP0929810A2 (en) Homogenous luminescence energy transfer assays
EP0973036A2 (en) Homogeneous luminescence assay method based on energy transfer
Deshpande Principles and applications of luminescence spectroscopy
JPH10508103A (ja) 臨床化学、免疫検定法、親和性検定法および生物医学研究の為の長寿命異方性（偏光性）プローブ
ES2974284T3 (es) Aminas de cadena ramificada en la detección de electroquimioluminiscencia
US20130171624A1 (en) Magnetic Binding Assays Utilizing Time-Resolved Up-Converting Luminescence Detection
ES2245947T3 (es) Procedimiento para determinar sustancias mediante el metodo de campo evanescente.
US20130171623A1 (en) Binding Assays Utilizing Time-Resolved Up-Converting Luminescence Detection
US20010021514A1 (en) Luminescent metal-ligand complexes
JPH01302144A (ja) 溶液中での電気発生のルミネセンスに基づく分析方法
US20190339283A1 (en) Bioconjugates of heterocyclic compounds
Miller Long-wavelength and near-infrared fluorescence: state of the art, future applications, and standards
Heuninck et al. Time-resolved FRET-based assays to characterize G protein-coupled receptor hetero-oligomer pharmacology
ES2327141T3 (es) Compuestos luminiscentes dotados de un brazo de enlace funcionalizado utilizado en bioconjugacion y marcado de biomoleculas.
CN104345048B (zh) 一种基于上转换发光物质检测生物分子的方法及实施其的检测系统
Savitsky Biomedical application of metalloporphyrins room-temperature phosphorescence
Brecht et al. Resonant Energy Transfer Detection for Low Volume Immunoassay in Environmental Applications
Seare Immunoassay techniques
Bathgate Development of Lanthanide-Labeled Human INSL3 as an Alternative Probe to Radioactively Labeled INSL3 for Use in Bioassays