DE50106822D1 - Farbstoffpaare für fluoreszenz-resonanz-energie-transfer (fret) messungen - Google Patents

Farbstoffpaare für fluoreszenz-resonanz-energie-transfer (fret) messungen

Info

Publication number
DE50106822D1
DE50106822D1 DE50106822T DE50106822T DE50106822D1 DE 50106822 D1 DE50106822 D1 DE 50106822D1 DE 50106822 T DE50106822 T DE 50106822T DE 50106822 T DE50106822 T DE 50106822T DE 50106822 D1 DE50106822 D1 DE 50106822D1
Authority
DE
Germany
Prior art keywords
dyes
energy transfer
resonance energy
fluorescence resonance
fret
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE50106822T
Other languages
German (de)
English (en)
Inventor
Daniel Belik
Hans-Dieter Josel
Rupert Herrmann
Bernhard Koenig
Francis Mueller
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Roche Diagnostics GmbH
Original Assignee
Roche Diagnostics GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Roche Diagnostics GmbH filed Critical Roche Diagnostics GmbH
Application granted granted Critical
Publication of DE50106822D1 publication Critical patent/DE50106822D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
    • G01N33/582—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with fluorescent label
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/536—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase
    • G01N33/542—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase with steric inhibition or signal modification, e.g. fluorescent quenching
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/14—Heterocyclic carbon compound [i.e., O, S, N, Se, Te, as only ring hetero atom]
    • Y10T436/142222—Hetero-O [e.g., ascorbic acid, etc.]
    • Y10T436/143333—Saccharide [e.g., DNA, etc.]

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
DE50106822T 2000-11-16 2001-11-14 Farbstoffpaare für fluoreszenz-resonanz-energie-transfer (fret) messungen Expired - Lifetime DE50106822D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP00124995 2000-11-16
PCT/EP2001/013152 WO2002041001A1 (de) 2000-11-16 2001-11-14 Farbstoffpaare für fluoreszenz-resonanz-energie-transfer (fret) messungen

Publications (1)

Publication Number Publication Date
DE50106822D1 true DE50106822D1 (de) 2005-08-25

Family

ID=8170391

Family Applications (1)

Application Number Title Priority Date Filing Date
DE50106822T Expired - Lifetime DE50106822D1 (de) 2000-11-16 2001-11-14 Farbstoffpaare für fluoreszenz-resonanz-energie-transfer (fret) messungen

Country Status (9)

Country Link
US (1) US6908769B2 (https=)
EP (1) EP1337851B1 (https=)
JP (1) JP3905838B2 (https=)
AT (1) ATE300050T1 (https=)
AU (1) AU2002221848A1 (https=)
CA (1) CA2426479C (https=)
DE (1) DE50106822D1 (https=)
ES (1) ES2245995T3 (https=)
WO (1) WO2002041001A1 (https=)

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EP1317511B1 (de) * 2000-09-06 2005-01-19 Evotec OAI AG Oxazinderivate
EP1543155A4 (en) * 2002-07-17 2006-08-16 Us Genomics Inc METHOD AND COMPOSITIONS FOR THE ANALYSIS OF POLYMERS USING CHIMERIC TAGS
DE602004006733T2 (de) * 2003-02-26 2008-01-31 Tomtom International B.V. Navigationseinheit und verfahren zum anzeigen alternativer routen
WO2005016934A1 (en) * 2003-08-18 2005-02-24 Novartis Ag 3h-phenoxazine derivatives suitable as near-infrared imaging agents, preparation an use thereof
CA2541075C (en) * 2003-10-01 2010-04-27 Wallac Oy Homogeneous time-resolved energy transfer assay
US8105849B2 (en) * 2004-02-27 2012-01-31 Board Of Regents, The University Of Texas System Integration of fluids and reagents into self-contained cartridges containing sensor elements
WO2005089524A2 (en) * 2004-03-19 2005-09-29 U.S. Genomics, Inc. Compositions and methods for detection of single molecules
US8883486B2 (en) 2004-05-04 2014-11-11 Universite De Montreal Arrestin biosensor
CN100473988C (zh) * 2004-07-08 2009-04-01 厦门大学 具有荧光共振能量转移特点的蛋白组合及其用途
US20090298196A1 (en) * 2005-01-28 2009-12-03 Uwabe Ken-Ichiro Quantitative measurement method for recombinant protein
US7826052B2 (en) 2005-05-24 2010-11-02 Hidex Oy Correction method and measurement device for anti-stokes photoluminescence measurement
WO2007016975A1 (en) 2005-07-29 2007-02-15 F. Hoffmann-La Roche Ag Kinase and phosphatase assays based on fret
FR2890174B1 (fr) * 2005-08-30 2009-04-24 Cis Bio Internat Sa Procede pour la mise en evidence d'un processus biologique par mesure d'un fret
WO2007056250A2 (en) * 2005-11-04 2007-05-18 U.S. Genomics, Inc. Heterogeneous assay of analytes in solution using polymers
USRE49362E1 (en) 2006-05-18 2023-01-10 Illumina Cambridge Limited Dye compounds and the use of their labelled conjugates
US20110098309A1 (en) * 2007-07-12 2011-04-28 Acumen Pharmaceuticals, Inc. Methods of inhibiting the formation of amyloid-beta diffusable ligands using acylhydrazide compounds
US8962677B2 (en) * 2007-07-12 2015-02-24 Acumen Pharmaceuticals, Inc. Methods of restoring cognitive ability using non-peptidic compounds
US20100294665A1 (en) * 2007-07-12 2010-11-25 Richard Allen Method and system for transferring and/or concentrating a sample
US9006283B2 (en) 2007-07-12 2015-04-14 Acumen Pharmaceuticals, Inc. Methods of modifying amyloid β oligomers using non-peptidic compounds
US9217024B2 (en) 2007-12-18 2015-12-22 Acumen Pharmaceuticals, Inc. ADDL receptor polypeptides, polynucleotides and host cells for recombinant production
WO2010117420A2 (en) 2009-03-30 2010-10-14 Pacific Biosciences Of California, Inc. Fret-labeled compounds and uses therefor
WO2010125314A1 (fr) * 2009-04-30 2010-11-04 Cis-Bio International Procede de detection de composes modulateurs de dimeres de proteines membranaires a domaine vft
JP6043288B2 (ja) 2010-09-15 2016-12-14 エンダセア， インコーポレイテッド 時間分解蛍光ベースのアッセイによるリポ多糖の測定のための使用方法およびキット
BR112013006951A2 (pt) 2010-09-23 2017-05-23 Eci Biotech Inc detecção ultrassensível de streptococcus beta hemolítico
US8569254B2 (en) 2010-12-10 2013-10-29 National Yang Ming University Methods for modulating the expression and aggregation of CAG-expanded gene product in cells and methods for identifying agents useful for doing the same
GB201714748D0 (en) * 2017-09-13 2017-10-25 Univ Oxford Innovation Ltd Single-molecule phenotyping and sequencing of nucleic acid molecules
CN109752552A (zh) * 2017-11-05 2019-05-14 江苏维赛科技生物发展有限公司 检测联苯的时间分辨荧光免疫试剂盒及其检测方法
US11293927B2 (en) 2018-04-30 2022-04-05 Ribon Therapeutics, Inc. Screening methods for PARP modulators
KR102267067B1 (ko) * 2020-01-16 2021-06-21 경희대학교 산학협력단 다이에틸싸이아노포스포네이트 검출용 형광 프로브 화합물 및 이의 용도

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0076695B1 (en) 1981-10-06 1985-02-20 The Board Of Trustees Of The Leland Stanford Junior University Fluorescent conjugates for analysis of molecules and cells
US4822733A (en) * 1985-05-28 1989-04-18 Amoco Corporation Lifetime-resolved assay procedures
DE4137934A1 (de) 1991-11-18 1993-05-19 Boehringer Mannheim Gmbh Neue pentacyklische verbindungen und ihre verwendung als absorptions- oder fluoreszenzfarbstoffe
US5246867A (en) * 1992-01-17 1993-09-21 University Of Maryland At Baltimore Determination and quantification of saccharides by luminescence lifetimes and energy transfer
US5622821A (en) * 1994-06-29 1997-04-22 The Regents Of The University Of California Luminescent lanthanide chelates and methods of use
JP4540754B2 (ja) * 1996-06-04 2010-09-08 ユニバーシティ オブ ユタ リサーチ ファウンデーション Ｐｃｒ中のハイブリダイゼーションのモニタリング
WO1998043072A1 (en) 1997-03-25 1998-10-01 Photonic Research Systems Limited Luminescence assays
AU3487499A (en) 1998-04-08 1999-10-25 Regents Of The University Of California, The Methods and reagents for targeting organic compounds to selected cellular locations
GB9811483D0 (en) * 1998-05-29 1998-07-29 Photonic Research Systems Limi Luminescence assay using cyclical excitation wavelength sequence
US5998146A (en) * 1998-07-17 1999-12-07 Wallac Oy Homogeneous luminescence assay method based on energy transfer
WO2000047693A1 (en) 1999-02-12 2000-08-17 Ljl Biosystems, Inc. Luminescent metal-ligand complexes

Also Published As

Publication number Publication date
WO2002041001A1 (de) 2002-05-23
AU2002221848A1 (en) 2002-05-27
ES2245995T3 (es) 2006-02-01
US6908769B2 (en) 2005-06-21
JP3905838B2 (ja) 2007-04-18
EP1337851A1 (de) 2003-08-27
CA2426479C (en) 2007-08-07
EP1337851B1 (de) 2005-07-20
ATE300050T1 (de) 2005-08-15
US20040076979A1 (en) 2004-04-22
CA2426479A1 (en) 2003-04-22
JP2004514139A (ja) 2004-05-13

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