ES2223031T3 - Procedimiento para la sintesis de (3as)-5,5-dioxo-2,3,3a,4-tetrahidro-1h-pirrolo(2,1-c)(1,2,4)benzotiadiazina. - Google Patents

Procedimiento para la sintesis de (3as)-5,5-dioxo-2,3,3a,4-tetrahidro-1h-pirrolo(2,1-c)(1,2,4)benzotiadiazina.

Info

Publication number
ES2223031T3
ES2223031T3 ES02290946T ES02290946T ES2223031T3 ES 2223031 T3 ES2223031 T3 ES 2223031T3 ES 02290946 T ES02290946 T ES 02290946T ES 02290946 T ES02290946 T ES 02290946T ES 2223031 T3 ES2223031 T3 ES 2223031T3
Authority
ES
Spain
Prior art keywords
formula
compound
dioxo
toluene
pyrrolo
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES02290946T
Other languages
English (en)
Spanish (es)
Inventor
Elsa Foucher
Gilles Thominot
Jean-Pierre Lecouve
James Andrew Ramsden
Christopher James Cobley
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Les Laboratoires Servier SAS
Original Assignee
Les Laboratoires Servier SAS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Les Laboratoires Servier SAS filed Critical Les Laboratoires Servier SAS
Application granted granted Critical
Publication of ES2223031T3 publication Critical patent/ES2223031T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/06—Peri-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Hospice & Palliative Care (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
ES02290946T 2001-04-18 2002-04-16 Procedimiento para la sintesis de (3as)-5,5-dioxo-2,3,3a,4-tetrahidro-1h-pirrolo(2,1-c)(1,2,4)benzotiadiazina. Expired - Lifetime ES2223031T3 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR0105226 2001-04-18
FR0105226A FR2823753B1 (fr) 2001-04-18 2001-04-18 Nouveau procede de synthese de la (3as)-5,5-dioxo-2,3,3a, 4-tetrahydro-1h-pyrrolo [2,1-c] [1,2,4] benzothiadiazine

Publications (1)

Publication Number Publication Date
ES2223031T3 true ES2223031T3 (es) 2005-02-16

Family

ID=8862416

Family Applications (1)

Application Number Title Priority Date Filing Date
ES02290946T Expired - Lifetime ES2223031T3 (es) 2001-04-18 2002-04-16 Procedimiento para la sintesis de (3as)-5,5-dioxo-2,3,3a,4-tetrahidro-1h-pirrolo(2,1-c)(1,2,4)benzotiadiazina.

Country Status (23)

Country Link
US (1) US6518422B2 (enExample)
EP (1) EP1251132B1 (enExample)
JP (1) JP4011956B2 (enExample)
KR (1) KR100468066B1 (enExample)
CN (1) CN1169811C (enExample)
AR (1) AR036871A1 (enExample)
AT (1) ATE269339T1 (enExample)
AU (1) AU782080B2 (enExample)
BR (1) BR0201307A (enExample)
CA (1) CA2382405C (enExample)
DE (1) DE60200627T2 (enExample)
DK (1) DK1251132T3 (enExample)
EA (1) EA004927B1 (enExample)
ES (1) ES2223031T3 (enExample)
FR (1) FR2823753B1 (enExample)
HU (1) HUP0201256A3 (enExample)
MX (1) MXPA02003639A (enExample)
NO (1) NO20021768L (enExample)
NZ (1) NZ518422A (enExample)
PL (1) PL353512A1 (enExample)
PT (1) PT1251132E (enExample)
SI (1) SI1251132T1 (enExample)
ZA (1) ZA200203085B (enExample)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2856065B1 (fr) * 2003-06-13 2005-08-19 Servier Lab Nouveaux derives de benzothiazine et benzothiadiazine, leur procede de preparation et les compositions pharmaceutiques qui les contiennent.
US20060014887A1 (en) * 2004-07-19 2006-01-19 3M Innovative Properties Company Method of hydrolyzing a dispersion of ionic fluoropolymer
FR2879201B1 (fr) * 2004-12-10 2007-02-16 Servier Lab Nouveaux derives de benzothiazine et benzothiadiazine, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
EP2230094B1 (de) 2009-03-20 2013-12-11 Kremstal Türenwerk GmbH Verfahren für das Beschichten von Plattenwerkstoffen

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3294791A (en) * 1966-03-14 1966-12-27 American Home Prod Tetrahydro-2, 5-methano-1, 2, 5-benzothiadiazepine 1, 1-dioxide
US3471483A (en) * 1967-11-09 1969-10-07 American Home Prod 1 - substituted - 2,3,3a - 4 - tetrahydro - 1h-pyrrolo(2,1 - c)(1,2,4)benzothiadiazine,5,5-dioxide
JPH06192272A (ja) * 1992-12-24 1994-07-12 Japan Tobacco Inc 新規なトリアゾロベンゾチアジアジン及びトリアゾロベンゾチアジアゼピン誘導体
FR2722502B1 (fr) * 1994-07-12 1996-08-23 Adir Nouveau derive de benzothiadiazine, son procede depreparation et les compositions pharmaceutiques qui le contiennent
FR2812291B1 (fr) * 2000-07-28 2002-12-13 Adir Nouveaux derives de benzothiadiazine, leur procede de preparation et les compositions pharmaceutiques qui les contiennent

Also Published As

Publication number Publication date
EP1251132B1 (fr) 2004-06-16
KR20020081148A (ko) 2002-10-26
CN1381455A (zh) 2002-11-27
BR0201307A (pt) 2003-06-10
DE60200627T2 (de) 2005-07-14
NZ518422A (en) 2002-12-20
CN1169811C (zh) 2004-10-06
PL353512A1 (en) 2002-10-21
ZA200203085B (en) 2002-11-25
NO20021768D0 (no) 2002-04-15
JP2003012674A (ja) 2003-01-15
CA2382405C (fr) 2007-03-06
DK1251132T3 (da) 2004-10-25
HUP0201256A2 (hu) 2002-12-28
FR2823753A1 (fr) 2002-10-25
NO20021768L (no) 2002-10-21
PT1251132E (pt) 2004-09-30
SI1251132T1 (en) 2004-10-31
HU0201256D0 (enExample) 2002-06-29
AU782080B2 (en) 2005-06-30
MXPA02003639A (es) 2004-11-12
AU3440502A (en) 2002-10-24
FR2823753B1 (fr) 2004-07-16
US20020161222A1 (en) 2002-10-31
EA004927B1 (ru) 2004-10-28
ATE269339T1 (de) 2004-07-15
HUP0201256A3 (en) 2004-11-29
US6518422B2 (en) 2003-02-11
JP4011956B2 (ja) 2007-11-21
KR100468066B1 (ko) 2005-01-24
AR036871A1 (es) 2004-10-13
EP1251132A1 (fr) 2002-10-23
EA200200378A3 (ru) 2002-12-26
CA2382405A1 (fr) 2002-10-18
DE60200627D1 (de) 2004-07-22
HK1049668A1 (en) 2003-05-23
EA200200378A2 (ru) 2002-10-31

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