AU782080B2 - New process for the synthesis of (3aS)-5,5-dioxo-2,3,3a,4-tetrahydro-1H- pyrrolo(2,1-c)(1,2,4)benzothiadiazine - Google Patents

New process for the synthesis of (3aS)-5,5-dioxo-2,3,3a,4-tetrahydro-1H- pyrrolo(2,1-c)(1,2,4)benzothiadiazine Download PDF

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Publication number
AU782080B2
AU782080B2 AU34405/02A AU3440502A AU782080B2 AU 782080 B2 AU782080 B2 AU 782080B2 AU 34405/02 A AU34405/02 A AU 34405/02A AU 3440502 A AU3440502 A AU 3440502A AU 782080 B2 AU782080 B2 AU 782080B2
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AU
Australia
Prior art keywords
formula
compound
benzothiadiazine
pyrrolo
toluene
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
AU34405/02A
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English (en)
Other versions
AU3440502A (en
Inventor
Christopher James Cobley
Elsa Foucher
Jean-Pierre Lecouve
James Andrew Ramsden
Gilles Thominot
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Les Laboratoires Servier SAS
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Les Laboratoires Servier SAS
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Application filed by Les Laboratoires Servier SAS filed Critical Les Laboratoires Servier SAS
Publication of AU3440502A publication Critical patent/AU3440502A/en
Application granted granted Critical
Publication of AU782080B2 publication Critical patent/AU782080B2/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/06—Peri-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Hospice & Palliative Care (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
AU34405/02A 2001-04-18 2002-04-18 New process for the synthesis of (3aS)-5,5-dioxo-2,3,3a,4-tetrahydro-1H- pyrrolo(2,1-c)(1,2,4)benzothiadiazine Ceased AU782080B2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR0105226 2001-04-18
FR0105226A FR2823753B1 (fr) 2001-04-18 2001-04-18 Nouveau procede de synthese de la (3as)-5,5-dioxo-2,3,3a, 4-tetrahydro-1h-pyrrolo [2,1-c] [1,2,4] benzothiadiazine

Publications (2)

Publication Number Publication Date
AU3440502A AU3440502A (en) 2002-10-24
AU782080B2 true AU782080B2 (en) 2005-06-30

Family

ID=8862416

Family Applications (1)

Application Number Title Priority Date Filing Date
AU34405/02A Ceased AU782080B2 (en) 2001-04-18 2002-04-18 New process for the synthesis of (3aS)-5,5-dioxo-2,3,3a,4-tetrahydro-1H- pyrrolo(2,1-c)(1,2,4)benzothiadiazine

Country Status (23)

Country Link
US (1) US6518422B2 (enExample)
EP (1) EP1251132B1 (enExample)
JP (1) JP4011956B2 (enExample)
KR (1) KR100468066B1 (enExample)
CN (1) CN1169811C (enExample)
AR (1) AR036871A1 (enExample)
AT (1) ATE269339T1 (enExample)
AU (1) AU782080B2 (enExample)
BR (1) BR0201307A (enExample)
CA (1) CA2382405C (enExample)
DE (1) DE60200627T2 (enExample)
DK (1) DK1251132T3 (enExample)
EA (1) EA004927B1 (enExample)
ES (1) ES2223031T3 (enExample)
FR (1) FR2823753B1 (enExample)
HU (1) HUP0201256A3 (enExample)
MX (1) MXPA02003639A (enExample)
NO (1) NO20021768L (enExample)
NZ (1) NZ518422A (enExample)
PL (1) PL353512A1 (enExample)
PT (1) PT1251132E (enExample)
SI (1) SI1251132T1 (enExample)
ZA (1) ZA200203085B (enExample)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2856065B1 (fr) * 2003-06-13 2005-08-19 Servier Lab Nouveaux derives de benzothiazine et benzothiadiazine, leur procede de preparation et les compositions pharmaceutiques qui les contiennent.
US20060014887A1 (en) * 2004-07-19 2006-01-19 3M Innovative Properties Company Method of hydrolyzing a dispersion of ionic fluoropolymer
FR2879201B1 (fr) * 2004-12-10 2007-02-16 Servier Lab Nouveaux derives de benzothiazine et benzothiadiazine, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
EP2230094B1 (de) 2009-03-20 2013-12-11 Kremstal Türenwerk GmbH Verfahren für das Beschichten von Plattenwerkstoffen

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0692484A1 (fr) * 1994-07-12 1996-01-17 Adir Et Compagnie Nouveau dérivé de benzothiadiazine, son procédé de préparation et les compositions pharmaceutiques qui le contiennent

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3294791A (en) * 1966-03-14 1966-12-27 American Home Prod Tetrahydro-2, 5-methano-1, 2, 5-benzothiadiazepine 1, 1-dioxide
US3471483A (en) * 1967-11-09 1969-10-07 American Home Prod 1 - substituted - 2,3,3a - 4 - tetrahydro - 1h-pyrrolo(2,1 - c)(1,2,4)benzothiadiazine,5,5-dioxide
JPH06192272A (ja) * 1992-12-24 1994-07-12 Japan Tobacco Inc 新規なトリアゾロベンゾチアジアジン及びトリアゾロベンゾチアジアゼピン誘導体
FR2812291B1 (fr) * 2000-07-28 2002-12-13 Adir Nouveaux derives de benzothiadiazine, leur procede de preparation et les compositions pharmaceutiques qui les contiennent

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0692484A1 (fr) * 1994-07-12 1996-01-17 Adir Et Compagnie Nouveau dérivé de benzothiadiazine, son procédé de préparation et les compositions pharmaceutiques qui le contiennent

Also Published As

Publication number Publication date
EP1251132B1 (fr) 2004-06-16
KR20020081148A (ko) 2002-10-26
CN1381455A (zh) 2002-11-27
BR0201307A (pt) 2003-06-10
DE60200627T2 (de) 2005-07-14
NZ518422A (en) 2002-12-20
CN1169811C (zh) 2004-10-06
PL353512A1 (en) 2002-10-21
ZA200203085B (en) 2002-11-25
NO20021768D0 (no) 2002-04-15
JP2003012674A (ja) 2003-01-15
CA2382405C (fr) 2007-03-06
DK1251132T3 (da) 2004-10-25
HUP0201256A2 (hu) 2002-12-28
FR2823753A1 (fr) 2002-10-25
NO20021768L (no) 2002-10-21
PT1251132E (pt) 2004-09-30
SI1251132T1 (en) 2004-10-31
HU0201256D0 (enExample) 2002-06-29
MXPA02003639A (es) 2004-11-12
AU3440502A (en) 2002-10-24
FR2823753B1 (fr) 2004-07-16
US20020161222A1 (en) 2002-10-31
EA004927B1 (ru) 2004-10-28
ATE269339T1 (de) 2004-07-15
HUP0201256A3 (en) 2004-11-29
US6518422B2 (en) 2003-02-11
JP4011956B2 (ja) 2007-11-21
ES2223031T3 (es) 2005-02-16
KR100468066B1 (ko) 2005-01-24
AR036871A1 (es) 2004-10-13
EP1251132A1 (fr) 2002-10-23
EA200200378A3 (ru) 2002-12-26
CA2382405A1 (fr) 2002-10-18
DE60200627D1 (de) 2004-07-22
HK1049668A1 (en) 2003-05-23
EA200200378A2 (ru) 2002-10-31

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