ES2194128T3 - Compuestos microciclicos constituidos de unidades de suboxido de carbono. - Google Patents

Compuestos microciclicos constituidos de unidades de suboxido de carbono.

Info

Publication number
ES2194128T3
ES2194128T3 ES96944678T ES96944678T ES2194128T3 ES 2194128 T3 ES2194128 T3 ES 2194128T3 ES 96944678 T ES96944678 T ES 96944678T ES 96944678 T ES96944678 T ES 96944678T ES 2194128 T3 ES2194128 T3 ES 2194128T3
Authority
ES
Spain
Prior art keywords
active substances
microciclical
suboxide
substances
carbon units
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES96944678T
Other languages
English (en)
Inventor
Franz Kerek
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Donatur Dr Kerek GmbH
Original Assignee
Donatur Dr Kerek GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Donatur Dr Kerek GmbH filed Critical Donatur Dr Kerek GmbH
Application granted granted Critical
Publication of ES2194128T3 publication Critical patent/ES2194128T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/564—Immunoassay; Biospecific binding assay; Materials therefor for pre-existing immune complex or autoimmune disease, i.e. systemic lupus erythematosus, rheumatoid arthritis, multiple sclerosis, rheumatoid factors or complement components C1-C9
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/365—Lactones
    • A61K31/366—Lactones having six-membered rings, e.g. delta-lactones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A61P21/04—Drugs for disorders of the muscular or neuromuscular system for myasthenia gravis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/22—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains four or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/18—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms containing at least two hetero rings condensed among themselves or condensed with a common carbocyclic ring system, e.g. rifamycin
    • C12P17/181—Heterocyclic compounds containing oxygen atoms as the only ring heteroatoms in the condensed system, e.g. Salinomycin, Septamycin

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Immunology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Hematology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Urology & Nephrology (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Biomedical Technology (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Rheumatology (AREA)
  • Food Science & Technology (AREA)
  • Inorganic Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • General Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Cell Biology (AREA)
  • Rehabilitation Therapy (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Physical Education & Sports Medicine (AREA)

Abstract

SE DESCRIBEN SUSTANCIAS CON ACTIVIDAD BIORREGULADORA CON UN ESQUELETO ESTRUCTURAL MACROCICLICO QUE SE SINTETIZA A PARTIR DE SUBOXIDOS DE CARBONO MEDIANTE CICLOOLIGOMERIZACION Y FORMACION ADICIONAL DE ESTRUCTURAS DE MACROCICLOS. ESTAS SUSTANCIAS ACTIVAS SE UTILIZAN COMO TALES Y/O COMO ADUCTOS ESTABLES CON OTRAS SUSTANCIAS CONOCIDAS. SE DESCRIBE LA CARACTERIZACION DE ESTAS SUSTANCIAS ACTIVAS ASI COMO SUS DERIVADOS ORGANICOS E INORGANICOS, PROCEDIMIENTOS PARA SU PRODUCCION SINTETICA, SU AISLAMIENTO Y PURIFICACION. TAMBIEN SE DESCRIBE LA UTILIZACION DE ESTAS SUSTANCIAS ACTIVAS PARA LA REGULACION ENZIMATICA Y BIORREGULACION, COMPOSICIONES MEDICAS QUE CONTIENEN ESTAS SUSTANCIAS ACTIVAS ASI COMO SU UTILIZACION EN EL DIAGNOSTICO Y LA TERAPIA.
ES96944678T 1996-01-05 1996-12-30 Compuestos microciclicos constituidos de unidades de suboxido de carbono. Expired - Lifetime ES2194128T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19600301A DE19600301C2 (de) 1996-01-05 1996-01-05 Durch Cyclooligomerisierung des einfachen Kohlensuboxids C¶3¶O¶2¶ aufgebaute makrocyclische Verbindungen, Verfahren zu deren Herstellung und Gewinnung sowie deren Verwendung

Publications (1)

Publication Number Publication Date
ES2194128T3 true ES2194128T3 (es) 2003-11-16

Family

ID=7782233

Family Applications (1)

Application Number Title Priority Date Filing Date
ES96944678T Expired - Lifetime ES2194128T3 (es) 1996-01-05 1996-12-30 Compuestos microciclicos constituidos de unidades de suboxido de carbono.

Country Status (26)

Country Link
US (1) US6187810B1 (es)
EP (1) EP0874851B1 (es)
JP (1) JP4195089B2 (es)
KR (1) KR19990077000A (es)
CN (1) CN1209132A (es)
AR (1) AR005350A1 (es)
AT (1) ATE233768T1 (es)
AU (1) AU1307497A (es)
BG (1) BG102599A (es)
BR (1) BR9612430A (es)
CA (1) CA2241870A1 (es)
CZ (1) CZ208898A3 (es)
DE (2) DE19600301C2 (es)
EE (1) EE9800211A (es)
ES (1) ES2194128T3 (es)
HR (1) HRP970002A2 (es)
HU (1) HUP9904191A2 (es)
IL (1) IL125165A0 (es)
JO (1) JO1945B1 (es)
PL (1) PL327657A1 (es)
SI (1) SI0874851T1 (es)
SK (1) SK88598A3 (es)
TR (1) TR199801288T2 (es)
TW (1) TW376386B (es)
WO (1) WO1997025333A2 (es)
ZA (1) ZA9714B (es)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AUPO280796A0 (en) * 1996-10-07 1996-10-31 Austin Research Institute, The Methods of activating or enhancing FC receptors
DE10260537A1 (de) 2002-12-21 2004-07-15 Kerek, Franz, Dr. Peptide mit hohem Cysteingehalt
WO2006039291A1 (en) * 2004-09-30 2006-04-13 Honeywell International Inc. Thermally conductive composite and uses for microelectronic packaging
US20060067055A1 (en) * 2004-09-30 2006-03-30 Heffner Kenneth H Thermally conductive composite and uses for microelectronic packaging

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2565115A (en) 1948-10-28 1951-08-21 Squibb & Sons Inc Method of obtaining a conjugated estrogen preparation
US2720483A (en) 1951-02-21 1955-10-11 Olin Mathieson Method of obtaining a conjugatedestrogen preparation

Also Published As

Publication number Publication date
DE69626548T2 (de) 2003-12-24
WO1997025333A3 (en) 1997-12-24
SI0874851T1 (en) 2003-10-31
EE9800211A (et) 1998-12-15
CZ208898A3 (cs) 1998-10-14
WO1997025333A2 (en) 1997-07-17
AR005350A1 (es) 1999-04-28
BG102599A (en) 1999-03-31
JO1945B1 (en) 1997-12-15
IL125165A0 (en) 1999-01-26
EP0874851B1 (en) 2003-03-05
US6187810B1 (en) 2001-02-13
DE19600301A1 (de) 1997-07-10
AU1307497A (en) 1997-08-01
SK88598A3 (en) 1998-12-02
DE69626548D1 (de) 2003-04-10
TW376386B (en) 1999-12-11
ZA9714B (en) 1997-07-23
KR19990077000A (ko) 1999-10-25
CA2241870A1 (en) 1997-07-17
JP2000503015A (ja) 2000-03-14
DE19600301C2 (de) 1999-12-09
BR9612430A (pt) 1999-12-28
EP0874851A2 (en) 1998-11-04
HRP970002A2 (en) 1998-04-30
PL327657A1 (en) 1998-12-21
HUP9904191A2 (hu) 2000-05-28
JP4195089B2 (ja) 2008-12-10
TR199801288T2 (xx) 1998-11-23
ATE233768T1 (de) 2003-03-15
CN1209132A (zh) 1999-02-24

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