ES2126618T3 - Procedimiento para el aislamiento y cultivo de celulas transformadas asi como empleo de estas celulas para la obtencion de anticuerpos especificos para el individuo. - Google Patents

Procedimiento para el aislamiento y cultivo de celulas transformadas asi como empleo de estas celulas para la obtencion de anticuerpos especificos para el individuo.

Info

Publication number
ES2126618T3
ES2126618T3 ES93113227T ES93113227T ES2126618T3 ES 2126618 T3 ES2126618 T3 ES 2126618T3 ES 93113227 T ES93113227 T ES 93113227T ES 93113227 T ES93113227 T ES 93113227T ES 2126618 T3 ES2126618 T3 ES 2126618T3
Authority
ES
Spain
Prior art keywords
cells
procedure
obtaining
individual
cultivation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES93113227T
Other languages
English (en)
Inventor
Ulrich Dr Kubler
Rainer Hoffmann
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Kubler Dr GmbH
Original Assignee
Kubler Dr GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=6466484&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ES2126618(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Kubler Dr GmbH filed Critical Kubler Dr GmbH
Application granted granted Critical
Publication of ES2126618T3 publication Critical patent/ES2126618T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0693—Tumour cells; Cancer cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/30—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/30—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
    • C07K16/3038—Kidney, bladder
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/30—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
    • C07K16/3046—Stomach, Intestines
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/30—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
    • C07K16/3069—Reproductive system, e.g. ovaria, uterus, testes, prostate
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0693—Tumour cells; Cancer cells
    • C12N5/0694—Cells of blood, e.g. leukemia cells, myeloma cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Cell Biology (AREA)
  • Biochemistry (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Oncology (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Reproductive Health (AREA)
  • Pregnancy & Childbirth (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Inorganic Compounds Of Heavy Metals (AREA)

Abstract

SE DESCRIBE UN PROCEDIMIENTO CON EL QUE ES POSIBLE SIN CORRER RIESGOS Y SIN ADICION DE SUSTANCIAS QUIMICAS U OTRAS SUSTANCIAS AUXILIARES EL OBTENER DE UN INDIVIDUO VIVO CELULAS TRANSFORMADAS Y ANTICUERPOS POLI O MONOCLONALES ESPECIFICOS AL INDIVIDUO, ORIENTADOS CONTRA LOS ANTIGENOS TUMORESPECIFICOS SOBRE ESTAS CELULAS TRANSFORMADAS, PARA FINES DIAGNOSTICOS Y TERAPEUTICOS.
ES93113227T 1992-08-26 1993-08-18 Procedimiento para el aislamiento y cultivo de celulas transformadas asi como empleo de estas celulas para la obtencion de anticuerpos especificos para el individuo. Expired - Lifetime ES2126618T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE4228389A DE4228389C2 (de) 1992-08-26 1992-08-26 Gewinnung und Kultivierung transformierter Zellen

Publications (1)

Publication Number Publication Date
ES2126618T3 true ES2126618T3 (es) 1999-04-01

Family

ID=6466484

Family Applications (1)

Application Number Title Priority Date Filing Date
ES93113227T Expired - Lifetime ES2126618T3 (es) 1992-08-26 1993-08-18 Procedimiento para el aislamiento y cultivo de celulas transformadas asi como empleo de estas celulas para la obtencion de anticuerpos especificos para el individuo.

Country Status (8)

Country Link
US (1) US5529903A (es)
EP (1) EP0584715B1 (es)
JP (1) JP3502125B2 (es)
AT (1) ATE174959T1 (es)
DE (4) DE4244715C2 (es)
DK (1) DK0584715T3 (es)
ES (1) ES2126618T3 (es)
GR (1) GR3029774T3 (es)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7659119B2 (en) 1996-02-12 2010-02-09 Argos Therapeutics, Inc. Method and compositions for obtaining mature dendritic cells
CA2251186A1 (en) * 1996-04-05 1997-10-16 The Johns Hopkins University A method of enriching rare cells
DE29708743U1 (de) * 1997-05-16 1998-09-17 Kuebler Gmbh Dr Apheresevorrichtung
US7396681B1 (en) 1998-03-27 2008-07-08 Gabriele Multhoff Application of Hsp70 proteins
DE19833738A1 (de) * 1998-07-27 2000-02-03 Michael Giesing Verfahren zur Isolierung von Krebszellen aus zellhaltigen Körperflüssigkeiten sowie Sets zur Durchführung dieses Verfahrens
JP2002529704A (ja) * 1998-10-29 2002-09-10 セル ワークス インコーポレイテッド 単一細胞の複数マーカー特徴付け
GB9827430D0 (en) * 1998-12-11 1999-02-03 Ludwig Inst Cancer Res Differential expression in primary breast cancer
AU2412800A (en) * 1999-01-15 2000-08-01 Light Sciences Corporation Noninvasive vascular therapy
EP2359689B1 (en) 2002-09-27 2015-08-26 The General Hospital Corporation Microfluidic device for cell separation and use thereof
DE10317389A1 (de) 2003-04-15 2004-11-04 Dr. Kübler GmbH Synergistisch wirkende Kombination von Phenylbutyrat und Aminobenzoesäure zur Krebstherapie
DE10355702A1 (de) * 2003-06-12 2005-01-13 Kübler, Ulrich, Dr. Methode zur Diagnose und Therapie von Gliomen und Astrozytomen in einem sehr frühen Stadium
DE10342322B4 (de) * 2003-09-12 2006-06-22 Kübler, Ulrich, Dr. Verfahren zur Herstellung von endothelialen Progenitorzellen aus apheretisch gewonnenen Monozyten menschlichen oder tierischen Blutes
US8921102B2 (en) 2005-07-29 2014-12-30 Gpb Scientific, Llc Devices and methods for enrichment and alteration of circulating tumor cells and other particles
WO2007106545A2 (en) * 2006-03-13 2007-09-20 Veridex, Llc Propagation of primary cells
EP2029779A4 (en) 2006-06-14 2010-01-20 Living Microsystems Inc HIGHLY PARALLEL SNP GENOTYPING UTILIZATION FOR FETAL DIAGNOSIS
US8137912B2 (en) 2006-06-14 2012-03-20 The General Hospital Corporation Methods for the diagnosis of fetal abnormalities
EP2589668A1 (en) 2006-06-14 2013-05-08 Verinata Health, Inc Rare cell analysis using sample splitting and DNA tags
WO2008111990A1 (en) * 2006-06-14 2008-09-18 Cellpoint Diagnostics, Inc. Rare cell analysis using sample splitting and dna tags
US20080050739A1 (en) 2006-06-14 2008-02-28 Roland Stoughton Diagnosis of fetal abnormalities using polymorphisms including short tandem repeats
PL2562268T3 (pl) 2008-09-20 2017-06-30 The Board Of Trustees Of The Leland Stanford Junior University Nieinwazyjna diagnostyka aneuploidii płodu za pomocą sekwencjonowania
US20120170966A1 (en) * 2011-01-03 2012-07-05 Novak Jr James Russell Writing implement with storage enclosure
WO2019204391A1 (en) * 2018-04-19 2019-10-24 Robert Caruso Cryo-inactivated cancer cells for cancer immunotherapy

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2925789A (en) * 1987-12-17 1989-07-19 Browning's Clinical Pathology Services Limited Lymphokine activation of cells for adoptive immunotherapy, e.g. of hiv infection
WO1989007445A1 (en) * 1988-02-11 1989-08-24 Board Of Regents, The University Of Texas System Improved method for treatment of cancer with activated oncolytic leukocytes
US5112298A (en) * 1990-06-25 1992-05-12 Baxter International Inc. Apheresis method and device

Also Published As

Publication number Publication date
GR3029774T3 (en) 1999-06-30
EP0584715B1 (de) 1998-12-23
EP0584715A2 (de) 1994-03-02
DE59309239D1 (de) 1999-02-04
EP0584715A3 (de) 1995-02-22
DE9321535U1 (de) 1999-08-05
DK0584715T3 (da) 1999-08-23
ATE174959T1 (de) 1999-01-15
DE4244715A1 (de) 1994-04-28
DE4228389C2 (de) 1994-07-21
US5529903A (en) 1996-06-25
JP3502125B2 (ja) 2004-03-02
DE4244715C2 (de) 1995-06-14
JPH06205671A (ja) 1994-07-26
DE4228389A1 (de) 1994-03-03

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