ES2193130T3 - Procedimiento para incrementar la acumulacion de esteroles en plantas. - Google Patents
Procedimiento para incrementar la acumulacion de esteroles en plantas.Info
- Publication number
- ES2193130T3 ES2193130T3 ES91309338T ES91309338T ES2193130T3 ES 2193130 T3 ES2193130 T3 ES 2193130T3 ES 91309338 T ES91309338 T ES 91309338T ES 91309338 T ES91309338 T ES 91309338T ES 2193130 T3 ES2193130 T3 ES 2193130T3
- Authority
- ES
- Spain
- Prior art keywords
- plants
- accumulation
- polypeptide
- increasing
- increase
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/0004—Oxidoreductases (1.)
- C12N9/0006—Oxidoreductases (1.) acting on CH-OH groups as donors (1.1)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
- C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
- C12N15/8242—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits
- C12N15/8243—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits involving biosynthetic or metabolic pathways, i.e. metabolic engineering, e.g. nicotine, caffeine
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
- C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
- C12N15/8261—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield
- C12N15/8271—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for stress resistance, e.g. heavy metal resistance
- C12N15/8279—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for stress resistance, e.g. heavy metal resistance for biotic stress resistance, pathogen resistance, disease resistance
- C12N15/8286—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for stress resistance, e.g. heavy metal resistance for biotic stress resistance, pathogen resistance, disease resistance for insect resistance
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A40/00—Adaptation technologies in agriculture, forestry, livestock or agroalimentary production
- Y02A40/10—Adaptation technologies in agriculture, forestry, livestock or agroalimentary production in agriculture
- Y02A40/146—Genetically Modified [GMO] plants, e.g. transgenic plants
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Genetics & Genomics (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Biotechnology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Wood Science & Technology (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- Cell Biology (AREA)
- Plant Pathology (AREA)
- Biophysics (AREA)
- Physics & Mathematics (AREA)
- Nutrition Science (AREA)
- Insects & Arthropods (AREA)
- Pest Control & Pesticides (AREA)
- Medicinal Chemistry (AREA)
- Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Enzymes And Modification Thereof (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
Abstract
SE DESCRIBE UN METODO PARA INCREMENTAR LA ACUMULACION DE ESTEROL EN UNA PLANTA AL INCREMENTAR EL NUMERO DE COPIAS DE UN GEN CODIFICANDO UN POLIPEPTIDO TENIENDO ACTIVIDAD DE REDUCTASA HMG-COA. EL NUMERO DE COPIAS SE INCREMENTA PREFERENTEMENTE AL TRANSFORMAR LAS PLANTAS CON UNA MOLECULA DE ADN RECOMBINANTE QUE COMPRENDE UN VECTOR UNIDO OPERATIVAMENTE A UN SEGMENTO DE ADN EXOGENO QUE CODIFICA UN POLIPEPTIDO CON ACTIVIDAD DE REDUCTASA HMG-COA, Y UN PROMOTOR APROPIADO PARA DIRIGIR LA EXPRESION DE TAL POLIPEPTIDO. TAMBIEN SE DESCRIBE UN METODO PARA INCREMENTAR LA ACUMULACION DE CICLOCERTENOL EN UNA PLANTA, UN METODO PARA INCREMENTAR LA RESISTENCIA DE PLANTAS A LAS PARTES Y LAS PLANTAS TRANSFORMADAS EN SI MISMAS.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US07/596,467 US5306862A (en) | 1990-10-12 | 1990-10-12 | Method and composition for increasing sterol accumulation in higher plants |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2193130T3 true ES2193130T3 (es) | 2003-11-01 |
Family
ID=24387385
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES91309338T Expired - Lifetime ES2193130T3 (es) | 1990-10-12 | 1991-10-10 | Procedimiento para incrementar la acumulacion de esteroles en plantas. |
Country Status (10)
Country | Link |
---|---|
US (4) | US5306862A (es) |
EP (1) | EP0480730B1 (es) |
JP (1) | JP3594623B2 (es) |
AU (1) | AU653748B2 (es) |
CA (1) | CA2052792C (es) |
DE (1) | DE69133202T2 (es) |
ES (1) | ES2193130T3 (es) |
MX (1) | MX9101504A (es) |
TR (1) | TR25647A (es) |
ZA (1) | ZA917925B (es) |
Families Citing this family (78)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5545816A (en) * | 1990-03-02 | 1996-08-13 | Amoco Corporation | Phytoene biosynthesis in genetically engineered hosts |
WO1991013078A1 (en) * | 1990-03-02 | 1991-09-05 | Amoco Corporation | Biosynthesis of carotenoids in genetically engineered hosts |
US5530188A (en) * | 1990-03-02 | 1996-06-25 | Amoco Corporation | Beta-carotene biosynthesis in genetically engineered hosts |
US5306862A (en) * | 1990-10-12 | 1994-04-26 | Amoco Corporation | Method and composition for increasing sterol accumulation in higher plants |
FR2687284B1 (fr) * | 1992-02-14 | 1995-06-23 | Verneuil Rech | Plante portant des genes codant pour des enzymes de la voie de biosynthese des phytosterols, et procede d'obtention. |
CA2148451A1 (en) * | 1992-11-02 | 1994-05-11 | Peter Christiaan Sijmons | Plants with reduced susceptibility to plant-parasitic nematodes |
DE4423022C1 (de) * | 1994-06-30 | 1995-05-24 | Lutz Prof Dr Heide | Transgene Pflanzen mit erhöhtem Gehalt an Sekundärstoffen |
US5741898A (en) * | 1994-09-22 | 1998-04-21 | Hanley; Kathleen Marie | DNA sequence encoding nicotiana squalene synthetase |
US6310194B1 (en) * | 1994-09-26 | 2001-10-30 | Carnegie Institution Of Washington | Plant fatty acid hydroxylases |
US5576197A (en) * | 1995-04-07 | 1996-11-19 | Molecular Bio-Products | Polymerase chain reaction container and methods of using the same |
US5965793A (en) | 1995-09-20 | 1999-10-12 | Monsanto Company, Inc. | Strong early seed-specific gene regulatory region |
US5705624A (en) * | 1995-12-27 | 1998-01-06 | Fitzmaurice; Wayne Paul | DNA sequences encoding enzymes useful in phytoene biosynthesis |
WO1997034003A1 (en) * | 1996-03-13 | 1997-09-18 | National Research Council Of Canada | Process of raising squalene levels in plants and dna sequences used therefor |
US5952545A (en) * | 1996-03-27 | 1999-09-14 | Max-Planck-Gesellschaft Zur Forderung Der Wissenschaften E.V. | Nucleic acid molecules encoding cytochrome P450-type proteins involved in the brassinosteroid synthesis in plants |
US8106260B2 (en) * | 1996-04-12 | 2012-01-31 | The Board Of Trustees Of The University Of Kentucky | Chimeric isoprenoid synthases and uses thereof |
US5850019A (en) * | 1996-08-06 | 1998-12-15 | University Of Kentucky Research Foundation | Promoter (FLt) for the full-length transcript of peanut chlorotic streak caulimovirus (PCLSV) and expression of chimeric genes in plants |
US6093695A (en) | 1996-09-26 | 2000-07-25 | Monsanto Company | Bacillus thuringiensis CryET29 compositions toxic to coleopteran insects and ctenocephalides SPP |
CA2268816A1 (en) * | 1996-10-21 | 1998-04-30 | Martina Baltrusch (Deceased) | Sterol glycosyl transferases |
CA2276087A1 (en) * | 1996-12-26 | 1998-10-15 | Monsanto Company | Transgenic plants with modified sterol biosynthetic pathways |
US7087420B1 (en) | 1997-07-17 | 2006-08-08 | Cambia | Microbial β-glucuronidase genes, gene products and uses thereof |
US6391547B1 (en) * | 1997-09-09 | 2002-05-21 | Center For The Application Of Molecular Biology To International Agriculture | Microbial β-glucuronidase genes, gene products and uses thereof |
KR20010042069A (ko) * | 1998-03-20 | 2001-05-25 | 베니텍 오스트레일리아 리미티드 | 유전자 발현 조절방법 |
AUPP249298A0 (en) | 1998-03-20 | 1998-04-23 | Ag-Gene Australia Limited | Synthetic genes and genetic constructs comprising same I |
US8598332B1 (en) | 1998-04-08 | 2013-12-03 | Bayer Cropscience N.V. | Methods and means for obtaining modified phenotypes |
US20040214330A1 (en) * | 1999-04-07 | 2004-10-28 | Waterhouse Peter Michael | Methods and means for obtaining modified phenotypes |
WO2000008190A2 (en) * | 1998-08-03 | 2000-02-17 | Arizona Board Of Regents On Behalf Of The University Of Arizona | Sterol methyltransferase gene |
AR022383A1 (es) | 1998-09-18 | 2002-09-04 | Univ Kentucky Res Found | Sintasas |
CA2372120A1 (en) * | 1999-04-12 | 2000-10-19 | Monsanto Company | Transgenic plants containing altered levels of sterol compounds and tocopherols |
US6790669B1 (en) * | 1999-07-13 | 2004-09-14 | The Dow Chemical Company | Method for chemical analysis of biological material |
US6423885B1 (en) * | 1999-08-13 | 2002-07-23 | Commonwealth Scientific And Industrial Research Organization (Csiro) | Methods for obtaining modified phenotypes in plant cells |
BR0014934A (pt) * | 1999-10-27 | 2002-06-18 | Unilever Nv | Usos de um gene que expressa uma hmg-redutase sem retro-inibição e de um gene heterólogo que expressa uma hmg-redutase sem retro-inibição truncada, método de obtenção de sementes, planta, tecido de planta, sementes, método de obtenção de óleo, e, produto alimentìcio |
GB9925453D0 (en) * | 1999-10-27 | 1999-12-29 | Univ Bristol | Increasing isoprenoid biosynthesis |
CA2406076A1 (en) * | 2000-04-14 | 2001-10-25 | Unilever Plc | Process for modifying plants |
US20030033626A1 (en) | 2000-07-31 | 2003-02-13 | Hahn Frederick M. | Manipulation of genes of the mevalonate and isoprenoid pathways to create novel traits in transgenic organisms |
US7741533B2 (en) * | 2000-11-07 | 2010-06-22 | Pioneer Hi-Bred International, Inc. | Grain quality through altered expression of seed proteins |
US20040019192A1 (en) * | 2000-11-24 | 2004-01-29 | Mark Harker | Process for modifying plants |
EP1354955A4 (en) | 2000-12-28 | 2005-01-05 | Toyota Motor Co Ltd | PROCESS FOR PREPARING PRENYL ALCOHOL |
EP1354956A4 (en) | 2000-12-28 | 2004-10-27 | Toyota Motor Co Ltd | PROCESS FOR PRODUCING PRENYL ALCOHOL |
US6822142B2 (en) * | 2001-01-05 | 2004-11-23 | Monsanto Company | Transgenic plants containing altered levels of steroid compounds |
US7405057B2 (en) | 2001-03-09 | 2008-07-29 | Board Of Trustees Of The University Of Kentucky | Cytochrome P450s and uses thereof |
DE60335469D1 (de) * | 2002-07-02 | 2011-02-03 | Univ Texas | Radioaktiv markierte verbindungen und liposome und ihre herstellungs- und anwendungsverfahren |
US7442785B2 (en) * | 2003-07-24 | 2008-10-28 | The University Of Kentucky Research Foundation | Sesquiterpene synthase gene and protein |
EP1871883A1 (en) * | 2005-03-02 | 2008-01-02 | Metanomics GmbH | Process for the production of fine chemicals |
KR101482081B1 (ko) | 2005-03-18 | 2015-01-13 | 마이크로비아 인크. | 유질 효모와 진균 내에서 카로티노이드의 생산 |
CA2601605C (en) | 2005-03-21 | 2014-09-09 | The Regents Of The University Of California | Methods for selecting drought resistant plants |
WO2007004104A2 (en) | 2005-07-01 | 2007-01-11 | University Of Kentucky Research Foundation | Transformed plants accumulating mono- and/or sesquiterpenes |
US7750210B2 (en) | 2005-11-07 | 2010-07-06 | E. I. Du Pont De Nemours And Company | Compositions with increased phytosterol levels obtained from plants with decreased triterpene saponin levels |
EP2078092A2 (en) | 2006-09-28 | 2009-07-15 | Microbia, Inc. | Production of carotenoids in oleaginous yeast and fungi |
SG191671A1 (en) * | 2007-12-13 | 2013-07-31 | Danisco Us Inc | Cultured cells that produce isoprene and methods for producing isoprene |
ES2447371T3 (es) | 2008-04-14 | 2014-03-11 | Bridgestone Corporation | Proceso para recuperar caucho a partir de látex de caucho natural |
AU2009240505B2 (en) | 2008-04-23 | 2013-09-05 | Danisco Us Inc. | Isoprene synthase variants for improved microbial production of isoprene |
CA2759700A1 (en) | 2009-04-23 | 2010-10-28 | Danisco Us Inc. | Three-dimensional structure of isoprene synthase and its use thereof for generating variants |
WO2010122405A2 (en) * | 2009-04-23 | 2010-10-28 | Avesthagen Limited | A method for over expression of chemical constituents in plants |
EP2292741A1 (en) * | 2009-08-26 | 2011-03-09 | OrganoBalance GmbH | Genetically modified organisms for the production of lipids |
BR112012030836B8 (pt) * | 2010-06-02 | 2024-02-06 | Evolva Nutrition Inc | Hospedeiro recombinante que compreende genes recombinantes para produção de esteviol ou glicosídeo de esteviol, método para produzir esteviol, glicosídeo de esteviol ou composição de glicosídeo de esteviol e método para sintetizar esteviol ou glicosídeo de esteviol |
EP2633043A2 (en) | 2010-10-27 | 2013-09-04 | Danisco US Inc. | Isoprene synthase variants for improved production of isoprene |
BR122021015509B1 (pt) | 2011-08-08 | 2022-03-29 | Evolva Sa | Método para produzir um glicosídeo de esteviol alvo |
JP6126597B2 (ja) | 2011-08-08 | 2017-05-10 | エヴォルヴァ エスアー.Evolva Sa. | サフラン化合物の組換え生成のための方法および材料 |
CN110283260B (zh) | 2012-03-06 | 2021-09-28 | 株式会社普利司通 | 用于从经陈化的压块收取橡胶的方法和包含来自非三叶胶植物的植物物质的经陈化的压块 |
US9163263B2 (en) | 2012-05-02 | 2015-10-20 | The Goodyear Tire & Rubber Company | Identification of isoprene synthase variants with improved properties for the production of isoprene |
US10023660B2 (en) | 2012-05-16 | 2018-07-17 | Bridgestone Corporation | Compositions containing purified non-hevea rubber and related purification methods |
ES2740752T3 (es) | 2012-06-18 | 2020-02-06 | Bridgestone Corp | Método para la extracción con disolvente del bagazo |
AU2013277286B2 (en) | 2012-06-18 | 2016-06-30 | Bridgestone Corporation | Methods for increasing the extractable rubber content of non-Hevea plant matter |
AU2013277335B2 (en) | 2012-06-18 | 2016-08-11 | Bridgestone Corporation | Systems and methods for the management of waste associated with processing guayule shrubs to extract rubber |
CA2899276C (en) | 2013-02-06 | 2022-11-01 | Evolva Sa | Methods for improved production of rebaudioside d and rebaudioside m |
SG10201705993YA (en) | 2013-02-11 | 2017-08-30 | Evolva Sa | Efficient production of steviol glycosides in recombinant hosts |
WO2015038707A1 (en) | 2013-09-11 | 2015-03-19 | Bridgestone Corporation | Processes for the removal of rubber from tks plant matter |
EP3130672A4 (en) * | 2014-04-09 | 2017-12-20 | Adeka Corporation | Mutant enzyme and production method for terpenoid using said mutant enzyme |
BR112017002783A2 (pt) | 2014-08-11 | 2017-12-19 | Evolva Sa | produção de glicosídeos de esteviol em hospedeiros recombinantes |
MX2017003130A (es) | 2014-09-09 | 2017-10-24 | Evolva Sa | Produccion de glucosidos de esteviol en hospederos recombinantes. |
CA2973674A1 (en) | 2015-01-30 | 2016-08-04 | Evolva Sa | Production of steviol glycosides in recombinant hosts |
CN115851470A (zh) | 2015-03-16 | 2023-03-28 | 帝斯曼知识产权资产管理有限公司 | Udp-糖基转移酶 |
AU2016307066A1 (en) | 2015-08-07 | 2018-02-08 | Evolva Sa | Production of steviol glycosides in recombinant hosts |
US10982249B2 (en) | 2016-04-13 | 2021-04-20 | Evolva Sa | Production of steviol glycosides in recombinant hosts |
CN109312378A (zh) | 2016-05-16 | 2019-02-05 | 埃沃尔瓦公司 | 在重组宿主中产生甜菊醇糖苷 |
US10372591B2 (en) | 2016-09-07 | 2019-08-06 | International Business Machines Corporation | Applying eye trackers monitoring for effective exploratory user interface testing |
US11396669B2 (en) | 2016-11-07 | 2022-07-26 | Evolva Sa | Production of steviol glycosides in recombinant hosts |
US10775105B2 (en) | 2018-11-19 | 2020-09-15 | Bridgestone Corporation | Methods for the desolventization of bagasse |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4956282A (en) * | 1985-07-29 | 1990-09-11 | Calgene, Inc. | Mammalian peptide expression in plant cells |
US4867742A (en) * | 1986-06-06 | 1989-09-19 | Reynaldo Calderon | Retrograde perfusion |
US5258300A (en) * | 1988-06-09 | 1993-11-02 | Molecular Genetics Research And Development Limited Partnership | Method of inducing lysine overproduction in plants |
GB8826356D0 (en) * | 1988-11-10 | 1988-12-14 | Ici Plc | Adp glucose-pyrophosphorylase |
US5306862A (en) * | 1990-10-12 | 1994-04-26 | Amoco Corporation | Method and composition for increasing sterol accumulation in higher plants |
-
1990
- 1990-10-12 US US07/596,467 patent/US5306862A/en not_active Expired - Lifetime
-
1991
- 1991-10-03 ZA ZA917925A patent/ZA917925B/xx unknown
- 1991-10-04 CA CA002052792A patent/CA2052792C/en not_active Expired - Lifetime
- 1991-10-08 AU AU85619/91A patent/AU653748B2/en not_active Expired
- 1991-10-09 MX MX9101504A patent/MX9101504A/es unknown
- 1991-10-09 TR TR91/0985A patent/TR25647A/xx unknown
- 1991-10-10 EP EP91309338A patent/EP0480730B1/en not_active Expired - Lifetime
- 1991-10-10 ES ES91309338T patent/ES2193130T3/es not_active Expired - Lifetime
- 1991-10-10 DE DE69133202T patent/DE69133202T2/de not_active Expired - Lifetime
- 1991-10-14 JP JP26501991A patent/JP3594623B2/ja not_active Expired - Lifetime
-
1992
- 1992-08-14 US US07/934,374 patent/US5349126A/en not_active Expired - Lifetime
-
1993
- 1993-09-09 US US08/119,263 patent/US5365017A/en not_active Expired - Lifetime
-
1994
- 1994-12-08 US US08/308,551 patent/US5589619A/en not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
US5365017A (en) | 1994-11-15 |
US5589619A (en) | 1996-12-31 |
JP3594623B2 (ja) | 2004-12-02 |
MX9101504A (es) | 1992-07-01 |
EP0480730A3 (en) | 1992-11-19 |
JPH05115298A (ja) | 1993-05-14 |
AU653748B2 (en) | 1994-10-13 |
EP0480730A2 (en) | 1992-04-15 |
AU8561991A (en) | 1992-04-16 |
ZA917925B (en) | 1992-08-26 |
CA2052792C (en) | 2006-11-28 |
EP0480730B1 (en) | 2003-03-05 |
DE69133202T2 (de) | 2003-12-11 |
TR25647A (tr) | 1993-07-01 |
DE69133202D1 (de) | 2003-04-10 |
CA2052792A1 (en) | 1992-04-13 |
US5349126A (en) | 1994-09-20 |
US5306862A (en) | 1994-04-26 |
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