ES2192190T3 - Fragmentos proteicos tensioactivos pulmonares. - Google Patents
Fragmentos proteicos tensioactivos pulmonares.Info
- Publication number
- ES2192190T3 ES2192190T3 ES93905865T ES93905865T ES2192190T3 ES 2192190 T3 ES2192190 T3 ES 2192190T3 ES 93905865 T ES93905865 T ES 93905865T ES 93905865 T ES93905865 T ES 93905865T ES 2192190 T3 ES2192190 T3 ES 2192190T3
- Authority
- ES
- Spain
- Prior art keywords
- pulmonary
- tensioactive
- fragments
- proteic fragments
- proteic
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 239000012634 fragment Substances 0.000 title abstract 3
- 230000002685 pulmonary effect Effects 0.000 title 1
- 102000004169 proteins and genes Human genes 0.000 abstract 2
- 108090000623 proteins and genes Proteins 0.000 abstract 2
- 230000000694 effects Effects 0.000 abstract 1
- 239000003580 lung surfactant Substances 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 230000000241 respiratory effect Effects 0.000 abstract 1
- 208000011580 syndromic disease Diseases 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/1703—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- A61K38/1709—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/785—Alveolar surfactant peptides; Pulmonary surfactant peptides
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- General Health & Medical Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Toxicology (AREA)
- Immunology (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pulmonology (AREA)
- Pharmacology & Pharmacy (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Marine Sciences & Fisheries (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US86691692A | 1992-04-10 | 1992-04-10 |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2192190T3 true ES2192190T3 (es) | 2003-10-01 |
Family
ID=25348718
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES93905865T Expired - Lifetime ES2192190T3 (es) | 1992-04-10 | 1993-02-09 | Fragmentos proteicos tensioactivos pulmonares. |
Country Status (8)
Families Citing this family (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6020307A (en) * | 1997-04-25 | 2000-02-01 | Ony, Inc. | Compositions and methods for isolating lung surfactant hydrophobic proteins SP-B and SP-C |
US6013764A (en) * | 1996-07-17 | 2000-01-11 | Ortho Pharmaceutical Corp. | Liquid phase peptide synthesis of KL-4 pulmonary surfactant |
US5958902A (en) * | 1997-04-16 | 1999-09-28 | Wisconsin Alumni Research Foundation | Method and composition for treating sleep apnea |
AU2003201A (en) * | 1999-12-01 | 2001-06-12 | Byk Gulden Lomberg Chemische Fabrik Gmbh | Novel use of lung surfactant |
US6660833B1 (en) | 2000-02-29 | 2003-12-09 | Harbor-Ucla Research And Education Institute | Respiratory distress syndrome therapy with peptide analogs of human SP-B |
US7464012B2 (en) * | 2004-12-10 | 2008-12-09 | L'air Liquide, Societe Anonyme A Directoire Et Conseil De Surveillance Pour L'etude Et L'exploitation Des Procedes Georges Claude | Simplified process simulator |
US7582312B2 (en) | 2004-11-15 | 2009-09-01 | Discovery Laboratories, Inc. | Methods to produce lung surfactant formulations via lyophilization and formulations and uses thereof |
US8337815B2 (en) * | 2004-12-23 | 2012-12-25 | Discovery Laboratories, Inc. | Pulmonary surfactant formulations |
PT1841458E (pt) | 2005-01-06 | 2012-04-10 | Discovery Lab Inc | Regime de tratamento com surfactante para tratar ou prevenir displasia broncopulmonar |
US20070010429A1 (en) * | 2005-05-03 | 2007-01-11 | The Hospital For Sick Children | Phospholipid formulations and uses thereof in lung disease detection and treatment |
PT103484B (pt) * | 2006-05-19 | 2008-03-31 | Univ Do Minho | Formulação com domínios de ligação hidrófobos e domínios de ligação a hidratos de carbono para aplicações cosméticas nomeadamente para tratamento de fibras queratinosas como o cabelo. |
BRPI0717177A2 (pt) * | 2006-09-19 | 2013-10-08 | Discovery Lab Inc | Formulações de tensoativo pulmonar e métodos para promoção de eliminação de muco |
EP2170270B1 (en) * | 2007-06-05 | 2016-01-13 | Paka Pulmonary Pharmaceuticals, Inc. | Compositions for delivering medicaments into the lungs, uses thereof |
CN102271666A (zh) | 2008-12-10 | 2011-12-07 | Paka肺部医药公司 | 用于向肺脏递送药物的方法和组合物 |
WO2013188016A2 (en) | 2012-05-04 | 2013-12-19 | Discovery Laboratories, Inc. | Surfactant therapy for exposure to ionizing radiation |
Family Cites Families (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4234475A (en) * | 1975-08-15 | 1980-11-18 | The Gillette Company | Reacting protein with organic acid |
US5055553A (en) * | 1985-09-26 | 1991-10-08 | Genetics Institute Inc. | Low molecular weight pulmonary surfactant proteins |
EP0290516A4 (en) * | 1986-10-24 | 1989-11-14 | Jeffrey A Whitsett | PROTEINS RELATED TO SURFACE-EFFECTIVE HYDROPHOBIC LUNG ACTIVE SUBSTANCES. |
JPH01501282A (ja) * | 1986-12-08 | 1989-05-11 | ホイツトセツト,ジエフリー エイ. | 肺胞疎水性界面活性物質関連タンパク質 |
US5164369A (en) * | 1988-01-06 | 1992-11-17 | The Scripps Research Institute | Pulmonary surfactant protein and related polypeptide |
US4861756A (en) * | 1988-03-08 | 1989-08-29 | Merrell Dow Pharmaceuticals Inc. | Synthetic pulmonary surfactant |
US5238920A (en) * | 1989-08-22 | 1993-08-24 | Abbott Laboratories | Pulmonary surfactant protein fragments |
DE69125750D1 (de) * | 1990-05-21 | 1997-05-28 | Abbott Lab | Fettsäure-Oberflächenaktives-Lungenprotein Konjate |
WO1992020357A1 (en) * | 1991-05-23 | 1992-11-26 | Merrell Dow Pharmaceuticals Inc. | Inhibitors of cathepsin g and elastase for preventing connective tissue degradation |
-
1993
- 1993-02-09 AU AU36625/93A patent/AU3662593A/en not_active Abandoned
- 1993-02-09 WO PCT/US1993/001197 patent/WO1993021221A1/en active IP Right Grant
- 1993-02-09 EP EP93905865A patent/EP0635028B1/en not_active Expired - Lifetime
- 1993-02-09 DE DE69332654T patent/DE69332654T2/de not_active Expired - Fee Related
- 1993-02-09 ES ES93905865T patent/ES2192190T3/es not_active Expired - Lifetime
- 1993-02-09 AT AT93905865T patent/ATE231522T1/de not_active IP Right Cessation
- 1993-05-15 TW TW082103868A patent/TW240170B/zh active
-
1994
- 1994-08-29 US US08/296,898 patent/US5547937A/en not_active Expired - Lifetime
-
1995
- 1995-05-04 US US08/435,019 patent/US5753621A/en not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
DE69332654T2 (de) | 2003-09-25 |
DE69332654D1 (de) | 2003-02-27 |
US5753621A (en) | 1998-05-19 |
WO1993021221A1 (en) | 1993-10-28 |
TW240170B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1995-02-11 |
EP0635028A1 (en) | 1995-01-25 |
ATE231522T1 (de) | 2003-02-15 |
AU3662593A (en) | 1993-11-18 |
US5547937A (en) | 1996-08-20 |
EP0635028A4 (en) | 1995-11-22 |
EP0635028B1 (en) | 2003-01-22 |
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