ES2191721T3 - Microparticulas reticuladas y su utilizacion como vehiculos terapeuticos. - Google Patents

Microparticulas reticuladas y su utilizacion como vehiculos terapeuticos.

Info

Publication number
ES2191721T3
ES2191721T3 ES95940381T ES95940381T ES2191721T3 ES 2191721 T3 ES2191721 T3 ES 2191721T3 ES 95940381 T ES95940381 T ES 95940381T ES 95940381 T ES95940381 T ES 95940381T ES 2191721 T3 ES2191721 T3 ES 2191721T3
Authority
ES
Spain
Prior art keywords
microparticles
reticulated
vehicles
water
therapeutic vehicles
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES95940381T
Other languages
English (en)
Inventor
Richard Alan Johnson
Andrew Derek Sutton
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Quadrant Drug Delivery Ltd
Original Assignee
Elan Drug Delivery Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Elan Drug Delivery Ltd filed Critical Elan Drug Delivery Ltd
Application granted granted Critical
Publication of ES2191721T3 publication Critical patent/ES2191721T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/22—Echographic preparations; Ultrasound imaging preparations ; Optoacoustic imaging preparations
    • A61K49/222—Echographic preparations; Ultrasound imaging preparations ; Optoacoustic imaging preparations characterised by a special physical form, e.g. emulsions, liposomes
    • A61K49/223—Microbubbles, hollow microspheres, free gas bubbles, gas microspheres
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/167—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction with an outer layer or coating comprising drug; with chemically bound drugs or non-active substances on their surface

Landscapes

  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Acoustics & Sound (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Radiology & Medical Imaging (AREA)
  • Medicinal Preparation (AREA)
  • Steroid Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

POLVO ESTERIL FORMADO POR MICROPARTICULAS DE 0,1 A 50 MI}M DE DIAMETRO, OBTENIDAS MEDIANTE DESHIDRATACION POR ASPERSION Y FORMACION DE ENLACES CRUZADOS DE UN MATERIAL HIPOSOLUBLE CON GRUPOS FUNCIONALES LIBRES, QUE SE CARACTERIZA POR QUE LAS MICROPARTICULAS SON HIDROFILICAS, PUEDE RECONSTITUIRSE EN AGUA PARA OBTENER UNA SUSPENSION MONODISPERSA Y CONSERVA DICHOS GRUPOS DISPONIBLES PARA LA DERIVATIZACION. LAS PARTICULAS SE UNEN A FARMACOS O A OTRAS MOLECULA FUNCIONALES Y SE UTILIZAN COMO EXCIPIENTES TERAPEUTICOS.
ES95940381T 1994-12-16 1995-12-14 Microparticulas reticuladas y su utilizacion como vehiculos terapeuticos. Expired - Lifetime ES2191721T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP94309417 1994-12-16

Publications (1)

Publication Number Publication Date
ES2191721T3 true ES2191721T3 (es) 2003-09-16

Family

ID=8217949

Family Applications (1)

Application Number Title Priority Date Filing Date
ES95940381T Expired - Lifetime ES2191721T3 (es) 1994-12-16 1995-12-14 Microparticulas reticuladas y su utilizacion como vehiculos terapeuticos.

Country Status (19)

Country Link
EP (1) EP0796090B1 (es)
JP (1) JP4350165B2 (es)
CN (1) CN1175208A (es)
AT (1) ATE234080T1 (es)
AU (1) AU692019B2 (es)
BR (1) BR9510462A (es)
CA (1) CA2207077C (es)
CZ (1) CZ183797A3 (es)
DE (1) DE69529917T2 (es)
DK (1) DK0796090T3 (es)
ES (1) ES2191721T3 (es)
FI (1) FI972546A (es)
HU (1) HUT77369A (es)
NO (1) NO972554L (es)
NZ (1) NZ297072A (es)
PL (1) PL321018A1 (es)
PT (1) PT796090E (es)
WO (1) WO1996018388A2 (es)
ZA (1) ZA9510702B (es)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6391343B1 (en) 1991-01-15 2002-05-21 Hemosphere, Inc. Fibrinogen-coated particles for therapeutic use
GB9423419D0 (en) 1994-11-19 1995-01-11 Andaris Ltd Preparation of hollow microcapsules
US5955108A (en) * 1994-12-16 1999-09-21 Quadrant Healthcare (Uk) Limited Cross-linked microparticles and their use as therapeutic vehicles
AU702955B2 (en) * 1996-05-17 1999-03-11 Quadrant Healthcare (Uk) Limited Microparticles and their use in wound therapy
GB9610830D0 (en) 1996-05-23 1996-07-31 Andaris Ltd Use of hollow microcapsules
GB9615435D0 (en) 1996-07-23 1996-09-04 Andaris Ltd Spray-dried product and its therapeutic use
US5977313A (en) * 1996-10-10 1999-11-02 Quadrant Healthcare Limited Platelet substitutes and conjugation methods suitable for their preparation
JP2002515887A (ja) * 1996-10-19 2002-05-28 クウォドラント、ヘルスケアー、（ユーケー）、リミテッド 診断および治療における中空マイクロカプセルの使用
GB9621825D0 (en) * 1996-10-19 1996-12-11 Andaris Ltd Microparticles and their use as therapeutic vehicles
US6068600A (en) * 1996-12-06 2000-05-30 Quadrant Healthcare (Uk) Limited Use of hollow microcapsules
EP0964676A1 (en) * 1997-01-30 1999-12-22 Quadrant Healthcare (UK) Limited Microparticles and their use in cancer treatment
CA2294494A1 (en) 1997-06-05 1998-12-10 Richard C. K. Yen Fibrinogen-coated microspheres
US20060165606A1 (en) 1997-09-29 2006-07-27 Nektar Therapeutics Pulmonary delivery particles comprising water insoluble or crystalline active agents
GB9724143D0 (en) * 1997-11-14 1998-01-14 Andaris Ltd Pharmaceutical conjugate
GB9825105D0 (en) * 1998-11-16 1999-01-13 Andaris Ltd Pharamaceutical conjugates
US7871598B1 (en) 2000-05-10 2011-01-18 Novartis Ag Stable metal ion-lipid powdered pharmaceutical compositions for drug delivery and methods of use
TWI324518B (en) 2001-12-19 2010-05-11 Nektar Therapeutics Pulmonary delivery of aminoglycosides
GB0323378D0 (en) * 2003-10-07 2003-11-05 Univ Leicester Therapeutic agent
RU2390529C2 (ru) * 2004-01-07 2010-05-27 Сейкагаку Корпорейшн Производное гиалуроновой кислоты и содержащее его лекарственное средство
GB0623607D0 (en) 2006-11-27 2007-01-03 Haemostatix Ltd Tissue adhesive
US7914999B2 (en) * 2006-12-29 2011-03-29 Abbott Laboratories Non-denaturing lysis reagent
GB0814302D0 (en) 2008-08-05 2008-10-01 Coretherapix Slu Compounds and methods
EP2216054A1 (en) 2009-02-06 2010-08-11 ProFibrix BV Biodegradable extravascular support
GB0909136D0 (en) 2009-05-28 2009-07-01 Profibrix Bv Dry powder composition
GB0909131D0 (en) 2009-05-28 2009-07-01 Quadrant Drug Delivery Ltd Dry powder fibrin sealant
CN102724968A (zh) 2010-01-08 2012-10-10 普罗菲布瑞克斯公司 干粉血纤蛋白密封剂
NO20110653A1 (no) 2011-05-02 2012-11-05 Spiro Medical As Respirasjonsovervakning
RU2013155713A (ru) 2011-07-06 2015-08-20 Профибрикс Бв Составы для лечения ран

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK0494417T3 (da) * 1991-01-10 1996-05-13 Basf Corp Fremgangsmåde til tværbinding af gelatine og til inkorporering af et materiale deri
GB9221329D0 (en) * 1992-10-10 1992-11-25 Delta Biotechnology Ltd Preparation of further diagnostic agents

Also Published As

Publication number Publication date
DE69529917D1 (de) 2003-04-17
JPH10510527A (ja) 1998-10-13
CZ183797A3 (en) 1997-11-12
DK0796090T3 (da) 2003-06-23
CA2207077C (en) 2007-02-06
PT796090E (pt) 2003-07-31
FI972546A0 (fi) 1997-06-16
AU692019B2 (en) 1998-05-28
ATE234080T1 (de) 2003-03-15
CN1175208A (zh) 1998-03-04
NO972554D0 (no) 1997-06-05
DE69529917T2 (de) 2003-12-11
FI972546A (fi) 1997-07-04
EP0796090B1 (en) 2003-03-12
JP4350165B2 (ja) 2009-10-21
HUT77369A (hu) 1998-03-30
BR9510462A (pt) 1998-12-15
NZ297072A (en) 1999-03-29
AU4184996A (en) 1996-07-03
PL321018A1 (en) 1997-11-24
MX9704503A (es) 1997-10-31
WO1996018388A3 (en) 1996-08-29
NO972554L (no) 1997-06-05
ZA9510702B (en) 1996-12-17
CA2207077A1 (en) 1996-06-20
WO1996018388A2 (en) 1996-06-20
EP0796090A2 (en) 1997-09-24

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