MX9704503A - Polvo esteril de materiales entrelazados y su uso. - Google Patents
Polvo esteril de materiales entrelazados y su uso.Info
- Publication number
- MX9704503A MX9704503A MX9704503A MX9704503A MX9704503A MX 9704503 A MX9704503 A MX 9704503A MX 9704503 A MX9704503 A MX 9704503A MX 9704503 A MX9704503 A MX 9704503A MX 9704503 A MX9704503 A MX 9704503A
- Authority
- MX
- Mexico
- Prior art keywords
- cross
- microparticles
- vehicles
- linked
- linked microparticles
- Prior art date
Links
- 239000011859 microparticle Substances 0.000 title abstract 3
- 230000001225 therapeutic effect Effects 0.000 title 1
- 238000004132 cross linking Methods 0.000 abstract 1
- 238000001212 derivatisation Methods 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 229940079593 drug Drugs 0.000 abstract 1
- 125000000524 functional group Chemical group 0.000 abstract 1
- 239000002245 particle Substances 0.000 abstract 1
- 239000000843 powder Substances 0.000 abstract 1
- 230000000717 retained effect Effects 0.000 abstract 1
- 239000002195 soluble material Substances 0.000 abstract 1
- 238000001694 spray drying Methods 0.000 abstract 1
- 239000000725 suspension Substances 0.000 abstract 1
- 238000002560 therapeutic procedure Methods 0.000 abstract 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/22—Echographic preparations; Ultrasound imaging preparations ; Optoacoustic imaging preparations
- A61K49/222—Echographic preparations; Ultrasound imaging preparations ; Optoacoustic imaging preparations characterised by a special physical form, e.g. emulsions, liposomes
- A61K49/223—Microbubbles, hollow microspheres, free gas bubbles, gas microspheres
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/167—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction with an outer layer or coating comprising drug; with chemically bound drugs or non-active substances on their surface
Landscapes
- Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Physics & Mathematics (AREA)
- Acoustics & Sound (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Radiology & Medical Imaging (AREA)
- Medicinal Preparation (AREA)
- Steroid Compounds (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Un polvo estéril que comprende micropartículas de 0.1 a 50 æm de diámetro obtenibles por medio de secado por aspersion y enlace con un material soluble en agua que tiene grupos fusionales libres, se caracteriza en que las micropartículas son hidrofílicas, pueden reconstituirse en agua para dar una suspension monodispersa y tienen dichos grupos retenidos disponibles para derivacion. Las partículas se enlazan a fármacos u otras moléculas funcionales y se usan como vehículos en la terapia.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP94309417.7 | 1994-12-16 | ||
| EP94309417 | 1994-12-16 | ||
| PCT/GB1995/002925 WO1996018388A2 (en) | 1994-12-16 | 1995-12-14 | Cross-linked microparticles and their use as therapeutic vehicles |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| MX9704503A true MX9704503A (es) | 1997-10-31 |
| MXPA97004503A MXPA97004503A (es) | 1998-07-03 |
Family
ID=
Also Published As
| Publication number | Publication date |
|---|---|
| NO972554L (no) | 1997-06-05 |
| CN1175208A (zh) | 1998-03-04 |
| EP0796090B1 (en) | 2003-03-12 |
| WO1996018388A3 (en) | 1996-08-29 |
| AU4184996A (en) | 1996-07-03 |
| AU692019B2 (en) | 1998-05-28 |
| NO972554D0 (no) | 1997-06-05 |
| CA2207077A1 (en) | 1996-06-20 |
| CZ183797A3 (en) | 1997-11-12 |
| JPH10510527A (ja) | 1998-10-13 |
| ATE234080T1 (de) | 2003-03-15 |
| PT796090E (pt) | 2003-07-31 |
| ZA9510702B (en) | 1996-12-17 |
| ES2191721T3 (es) | 2003-09-16 |
| FI972546A0 (fi) | 1997-06-16 |
| DE69529917T2 (de) | 2003-12-11 |
| BR9510462A (pt) | 1998-12-15 |
| HUT77369A (hu) | 1998-03-30 |
| NZ297072A (en) | 1999-03-29 |
| DK0796090T3 (da) | 2003-06-23 |
| CA2207077C (en) | 2007-02-06 |
| DE69529917D1 (de) | 2003-04-17 |
| WO1996018388A2 (en) | 1996-06-20 |
| PL321018A1 (en) | 1997-11-24 |
| FI972546A (fi) | 1997-07-04 |
| JP4350165B2 (ja) | 2009-10-21 |
| EP0796090A2 (en) | 1997-09-24 |
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