ES2190663T3 - Formulacion de un adhesivo de fibrina para tejidos y procedimiento para su fabricacion. - Google Patents

Formulacion de un adhesivo de fibrina para tejidos y procedimiento para su fabricacion.

Info

Publication number
ES2190663T3
ES2190663T3 ES99950784T ES99950784T ES2190663T3 ES 2190663 T3 ES2190663 T3 ES 2190663T3 ES 99950784 T ES99950784 T ES 99950784T ES 99950784 T ES99950784 T ES 99950784T ES 2190663 T3 ES2190663 T3 ES 2190663T3
Authority
ES
Spain
Prior art keywords
manufacture
formulation
fibrin tissue
granules
adhesive fibrin
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES99950784T
Other languages
English (en)
Other versions
ES2190663T5 (es
Inventor
Armin Prasch
Bernhard Luy
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Glatt Process Technology GmbH
Original Assignee
Glatt Process Technology GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=7885853&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ES2190663(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Glatt Process Technology GmbH filed Critical Glatt Process Technology GmbH
Application granted granted Critical
Publication of ES2190663T3 publication Critical patent/ES2190663T3/es
Publication of ES2190663T5 publication Critical patent/ES2190663T5/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L24/00—Surgical adhesives or cements; Adhesives for colostomy devices
    • A61L24/04—Surgical adhesives or cements; Adhesives for colostomy devices containing macromolecular materials
    • A61L24/10—Polypeptides; Proteins
    • A61L24/106—Fibrin; Fibrinogen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L24/00—Surgical adhesives or cements; Adhesives for colostomy devices
    • A61L24/04—Surgical adhesives or cements; Adhesives for colostomy devices containing macromolecular materials
    • A61L24/043—Mixtures of macromolecular materials

Landscapes

  • Health & Medical Sciences (AREA)
  • Surgery (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Materials For Medical Uses (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)

Abstract

Formulación de un adhesivo de fibrina para tejidos que contiene trombina, fibrinógeno y factor XIII, caracterizada porque la trombina y el fibrinógeno con el factor XIII están como mezcla en forma de granulado con capacidad de fluencia y sólido, habiéndose obtenido el granulado por secado de las soluciones o suspensiones de proteínas en un aparato de lecho fluidizado y porque el granulado presenta un tamaño de partículas de 40-1000 micram.
ES99950784T 1998-10-27 1999-10-27 Formulacion de un adhesivo de fibrina para tejidos y procedimiento para su fabricacion. Expired - Lifetime ES2190663T5 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19849589A DE19849589C1 (de) 1998-10-27 1998-10-27 Fibrin-Gewebekleber-Formulierung und Verfahren zu dessen Herstellung
DE19849589 1998-10-27

Publications (2)

Publication Number Publication Date
ES2190663T3 true ES2190663T3 (es) 2003-08-01
ES2190663T5 ES2190663T5 (es) 2009-06-15

Family

ID=7885853

Family Applications (1)

Application Number Title Priority Date Filing Date
ES99950784T Expired - Lifetime ES2190663T5 (es) 1998-10-27 1999-10-27 Formulacion de un adhesivo de fibrina para tejidos y procedimiento para su fabricacion.

Country Status (11)

Country Link
US (1) US6596318B2 (es)
EP (1) EP1124589B2 (es)
JP (1) JP2002528180A (es)
AT (1) ATE230618T1 (es)
AU (1) AU765770B2 (es)
CA (1) CA2349000C (es)
DE (2) DE19849589C1 (es)
DK (1) DK1124589T3 (es)
ES (1) ES2190663T5 (es)
RU (1) RU2242996C2 (es)
WO (1) WO2000024436A1 (es)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100804434B1 (ko) * 1998-12-23 2008-02-20 체에스엘 베링 게엠베하 피브린계 접착제 과립 및 이의 제조방법
US7572769B2 (en) * 1998-12-23 2009-08-11 Csl Behring Gmbh Fibrin adhesive granulate and method for its preparation
DE19962221A1 (de) * 1999-10-01 2001-05-23 Glatt Process Technology Gmbh Dispersionen für Depotapplikationen
US6468660B2 (en) 2000-12-29 2002-10-22 St. Jude Medical, Inc. Biocompatible adhesives
RU2345719C2 (ru) 2001-01-16 2009-02-10 Васкулар Терапиез, Ллс. Способ предотвращения или лечения уменьшения доступа для гемодиализа сосудов и устройство для его осуществления и другие сосудистые графты
AUPR272901A0 (en) * 2001-01-25 2001-02-22 Gainful Plan Limited Method of preparing biological materials and preparations produced using same
AU2005317689B2 (en) 2004-12-20 2011-05-12 Amo Groningen B.V. Amphiphilic block copolymers and their use
GB0623607D0 (en) 2006-11-27 2007-01-03 Haemostatix Ltd Tissue adhesive
US20080299182A1 (en) * 2007-03-01 2008-12-04 Shuyuan Zhang Methods and formulations for topical gene therapy
GB0909131D0 (en) * 2009-05-28 2009-07-01 Quadrant Drug Delivery Ltd Dry powder fibrin sealant
ES2593584T3 (es) * 2009-05-28 2016-12-09 Profibrix Bv Sellante de fibrina en polvo seco
GB0909129D0 (en) * 2009-05-28 2009-07-01 Quadrant Drug Delivery Ltd Dry powder fibrin sealant
GB0909136D0 (en) 2009-05-28 2009-07-01 Profibrix Bv Dry powder composition
CN102724968A (zh) * 2010-01-08 2012-10-10 普罗菲布瑞克斯公司 干粉血纤蛋白密封剂
RU2556960C2 (ru) * 2010-01-28 2015-07-20 Омрикс Биофармасьютикалс Лтд. Способ обеспечения улучшенного уплотнения с помощью фибрина
ES2688591T3 (es) 2011-03-28 2018-11-05 Ablynx N.V. Método para producir formulaciones sólidas que comprenden dominios variables individuales de inmunoglobulina
JP2016510059A (ja) * 2013-03-07 2016-04-04 プロフィブリックス・ベーフェー 粉末製剤
DE102013203999A1 (de) * 2013-03-08 2014-09-11 Aesculap Ag Gewebefusionsmittel
DE102013203997A1 (de) * 2013-03-08 2014-09-11 Aesculap Ag Medizinisches Produkt
DE102013203988A1 (de) 2013-03-08 2014-09-11 Aesculap Ag Gewebefusionsmittel
JP6926101B2 (ja) 2015-11-06 2021-08-25 エシコン・インコーポレイテッドＥｔｈｉｃｏｎ， Ｉｎｃ． 圧密止血セルロース系凝集体
CA3004849C (en) 2015-11-16 2024-06-11 Georges Gaudriault A method for morselizing and/or targeting pharmaceutically active principles to synovial tissue
US11413335B2 (en) 2018-02-13 2022-08-16 Guangzhou Bioseal Biotech Co. Ltd Hemostatic compositions and methods of making thereof
CN107754005B (zh) 2016-08-15 2021-06-15 广州倍绣生物技术有限公司 止血组合物及其制造方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4441167C1 (de) 1994-11-18 1996-03-14 Fraunhofer Ges Forschung Verfahren zur Trocknung von Blutplasma
US5658588A (en) * 1995-03-31 1997-08-19 University Of Cincinnati Fibrinogen-coated liposomes
AU702955B2 (en) * 1996-05-17 1999-03-11 Quadrant Healthcare (Uk) Limited Microparticles and their use in wound therapy
US6150505A (en) * 1997-09-19 2000-11-21 Hadasit Medical Research Services & Development Ltd. Fibrin microbeads prepared from fibrinogen, thrombin and factor XIII
KR100804434B1 (ko) † 1998-12-23 2008-02-20 체에스엘 베링 게엠베하 피브린계 접착제 과립 및 이의 제조방법

Also Published As

Publication number Publication date
ES2190663T5 (es) 2009-06-15
JP2002528180A (ja) 2002-09-03
WO2000024436A1 (de) 2000-05-04
EP1124589B1 (de) 2003-01-08
EP1124589B2 (de) 2009-02-25
ATE230618T1 (de) 2003-01-15
AU765770B2 (en) 2003-09-25
US20020037323A1 (en) 2002-03-28
WO2000024436A8 (de) 2000-09-21
EP1124589A1 (de) 2001-08-22
CA2349000A1 (en) 2000-05-04
US6596318B2 (en) 2003-07-22
DK1124589T3 (da) 2003-05-05
AU6342899A (en) 2000-05-15
DE59903994D1 (de) 2003-02-13
DE19849589C1 (de) 2000-06-15
RU2242996C2 (ru) 2004-12-27
CA2349000C (en) 2009-08-04

Similar Documents

Publication Publication Date Title
ES2190663T3 (es) Formulacion de un adhesivo de fibrina para tejidos y procedimiento para su fabricacion.
DE59902496D1 (de) Fibrinklebergranulat und verfahren zu dessen herstellung
DE69230670D1 (de) Zusammensetzungen, die eine blutgerinnselpolymermatrix zur verabreichung von osteogenen proteinen enthalten
ATE455564T1 (de) Molekularsieb-materialien mit vergrössertem teilchendurchmesser zur bildung von blutgerinnseln
FI961037A0 (fi) Valmisteet osteogenisten proteiinien antamiseksi
HUP0101141A2 (hu) Többkomponensű szuperabszorbens részecskék, ilyen részecskéket tartalmazó szuperabszorbens anyag, valamint eljárás vizes közeg elnyeletésére
DK0835667T3 (da) Vævklæbemiddel egnet til spröjtepåföring
ATE218365T1 (de) Stabilisierte mischung auf fibrinogenbasis
FR2526443B1 (fr) Activateur de plasminogene de tissu humain, son procede de production et composition pharmaceutique le contenant
ATE111360T1 (de) Chirurgisches klebstoffmaterial.
ATE15143T1 (de) Material zum abdichten und heilen von wunden und verfahren zu dessen herstellung.
DE69916856T2 (de) Micropartikeln zur verwendung in nadellosen injektion
ATE20824T1 (de) Angereichertes plasmaderivat zur unterstuetzung von wundverschluss und wundheilung.
RU2001111862A (ru) Состав фибринового тканевого адгезива и способ его получения
AU2036188A (en) New tissue plasminogen activator
DE69738170D1 (de) Konditioniertes Medium und diffusionsfähiges biologisches Material gewonnen durch Inkubierung von eingeschlossenen Zellen
DE60233030D1 (de) Tartrat- und phosphatsalz von 3,4-diaminopyridin, pharmazeutische zusammensetzung und deren verwendung
DE69009211D1 (de) Derivate von Thiazolidin-4-carbonsäure, deren Herstellung und sie enthaltende pharmazeutische Zusammensetzungen.
DE69907727D1 (de) Protein-disulfid-isomerasen enthaltende pharmazeutische zusammensetzungen
DE59708286D1 (de) Verwendung von wirkstoffmischungen, enthaltend phytostenole und/oder phytostenolester und potenzierungsmittel zur herstellung von hypocholesterinämischen mitteln
ATE231400T1 (de) Blutstillende zubereitung
TH10353EX (th) สารผสมควบคุมกลิ่นผสม
UA10419A (uk) Склад для з'єдhаhhя і заживлеhhя ткаhиh