ES2189285T3 - Nuevas piranonas, su procedimiento de preparacion y las composiciones farmaceuticas que las contienen - Google Patents
Nuevas piranonas, su procedimiento de preparacion y las composiciones farmaceuticas que las contienenInfo
- Publication number
- ES2189285T3 ES2189285T3 ES98965668T ES98965668T ES2189285T3 ES 2189285 T3 ES2189285 T3 ES 2189285T3 ES 98965668 T ES98965668 T ES 98965668T ES 98965668 T ES98965668 T ES 98965668T ES 2189285 T3 ES2189285 T3 ES 2189285T3
- Authority
- ES
- Spain
- Prior art keywords
- atoms
- moiety
- alkoxy
- piranonas
- new
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D407/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
- C07D407/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
- C07D407/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
- C07D309/34—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D309/36—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with oxygen atoms directly attached to ring carbon atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Biomedical Technology (AREA)
- Public Health (AREA)
- Pain & Pain Management (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Pyrane Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Abstract
2H-1-piran-2-onas de fórmula general I en la que R1 es un resto alquilo de 2 a 5 átomos de C, un resto cicloalquilo de 4 a 6 átomos de C, un resto cicloalquil-alquilo de 4 a 8 átomos de C o un resto alcoxi-alquilo con un total de 3 a 5 átomos de C, y R2 es un resto 2-fenil-etenilo sustituido en el anillo de benceno en las posiciones 3, 4 y 5 por R3, R4 y R5, siendo independientemente entre sí R3 y R5 metoxilo o etoxilo, y R4 un resto alcoxilo de cadena lineal o ramificado de 1 a 5 átomos de C, un resto alquenil-oxilo de 3 a 5 átomos de C, un resto cicloalcoxilo de 4 a 6 átomos de C, un resto cicloalquil-alcoxilo de 4 a 8 átomos de C o un resto alcoxi-alcoxilo con un total de 3 a 5 átomos de C.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE19750623A DE19750623A1 (de) | 1997-11-14 | 1997-11-14 | Pyranone, Verfahren zu ihrer Herstellung und Verwendung |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2189285T3 true ES2189285T3 (es) | 2003-07-01 |
Family
ID=7848824
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES98965668T Expired - Lifetime ES2189285T3 (es) | 1997-11-14 | 1998-11-12 | Nuevas piranonas, su procedimiento de preparacion y las composiciones farmaceuticas que las contienen |
Country Status (9)
Country | Link |
---|---|
US (1) | US6288109B1 (es) |
EP (1) | EP1032572B1 (es) |
JP (1) | JP2001523682A (es) |
AT (1) | ATE229526T1 (es) |
AU (1) | AU750666B2 (es) |
CA (1) | CA2310244A1 (es) |
DE (2) | DE19750623A1 (es) |
ES (1) | ES2189285T3 (es) |
WO (1) | WO1999025716A2 (es) |
Families Citing this family (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP1222925B1 (en) * | 2000-12-18 | 2005-02-23 | Meiji Dairies Corporation | Kavalactone as TNF-alpha production inhibitor |
US20050053678A1 (en) * | 2001-10-03 | 2005-03-10 | Gow Robert T. | Methods and compositions for betel nut chewing gum |
US20050069596A1 (en) * | 2001-10-03 | 2005-03-31 | Gow Robert T. | Compositions and methods comprising kava and anti-anxiety compounds |
US7029707B2 (en) * | 2001-10-03 | 2006-04-18 | Herbalscience, Llc | Method of producing a processed kava product having an altered kavalactone distribution and processed kava products produced using the same |
US7291352B2 (en) | 2001-10-03 | 2007-11-06 | Herbalscience Llc | Methods and compositions for oral delivery of Areca and mate' or theobromine |
US7001620B2 (en) | 2001-10-03 | 2006-02-21 | Herbal Science, Llc | Kavalactone product |
US7037524B2 (en) | 2001-10-03 | 2006-05-02 | Herbalscience, Llc | Oral delivery of a botanical |
US7105185B2 (en) * | 2001-10-03 | 2006-09-12 | Herbalscience, Llc | Kavalactone profile |
US20030118761A1 (en) * | 2001-12-21 | 2003-06-26 | Kimberly-Clark Worldwide, Inc. | Elastomeric articles having improved chemical resistance |
US20050037025A1 (en) * | 2002-10-03 | 2005-02-17 | Gow Robert T. | Methods and compositions comprising kava and mate' or theobromine |
US7294353B2 (en) * | 2003-10-24 | 2007-11-13 | Herbalscience, Llc | Methods and compositions comprising ilex |
CN1917892A (zh) * | 2003-10-24 | 2007-02-21 | 草本制药科学有限责任公司 | 包含冬青的方法和组合物 |
CN103145666B (zh) * | 2013-03-27 | 2015-04-22 | 山东省科学院生物研究所 | 4-取代α-吡喃酮衍生物及其制备方法与应用 |
CN106102758B (zh) | 2013-11-11 | 2020-09-22 | 夸利蒂赫布丘蒂克斯公司 | 卡瓦衍生的治疗性化合物及其使用方法 |
CN110551090B (zh) * | 2019-10-21 | 2021-06-18 | 扬州工业职业技术学院 | 一种超声波提取中药狗脊中抗肿瘤活性成分的方法 |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE1279683B (de) * | 1963-11-29 | 1968-10-10 | Spezialchemie Gmbh & Co | Verfahren zur Herstellung von substituierten ª‡-Pyronen |
DE1277263B (de) * | 1963-11-29 | 1968-09-12 | Spezialchemie Gmbh & Co | Verfahren zur Herstellung von Dihydromethysticin oder Dihydrokawain |
GB1061847A (en) | 1964-03-23 | 1967-03-15 | Mobil Oil Corp | Method for preparing highly siliceous zeolite type materials and the products thereof |
-
1997
- 1997-11-14 DE DE19750623A patent/DE19750623A1/de not_active Withdrawn
-
1998
- 1998-11-12 AU AU21528/99A patent/AU750666B2/en not_active Ceased
- 1998-11-12 CA CA002310244A patent/CA2310244A1/en not_active Abandoned
- 1998-11-12 AT AT98965668T patent/ATE229526T1/de not_active IP Right Cessation
- 1998-11-12 DE DE59806655T patent/DE59806655D1/de not_active Expired - Fee Related
- 1998-11-12 WO PCT/EP1998/007241 patent/WO1999025716A2/de active IP Right Grant
- 1998-11-12 EP EP98965668A patent/EP1032572B1/de not_active Expired - Lifetime
- 1998-11-12 ES ES98965668T patent/ES2189285T3/es not_active Expired - Lifetime
- 1998-11-12 JP JP2000521098A patent/JP2001523682A/ja active Pending
- 1998-11-12 US US09/554,382 patent/US6288109B1/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
JP2001523682A (ja) | 2001-11-27 |
CA2310244A1 (en) | 1999-05-27 |
EP1032572B1 (de) | 2002-12-11 |
WO1999025716A3 (de) | 1999-07-15 |
US6288109B1 (en) | 2001-09-11 |
AU750666B2 (en) | 2002-07-25 |
EP1032572A2 (de) | 2000-09-06 |
WO1999025716A9 (de) | 1999-09-02 |
DE59806655D1 (de) | 2003-01-23 |
ATE229526T1 (de) | 2002-12-15 |
WO1999025716A2 (de) | 1999-05-27 |
DE19750623A1 (de) | 1999-05-20 |
AU2152899A (en) | 1999-06-07 |
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