ES2178080T3 - Procedimiento para la preparacion de derivados de alcoxi-o ariloxi-pirazina. - Google Patents
Procedimiento para la preparacion de derivados de alcoxi-o ariloxi-pirazina.Info
- Publication number
- ES2178080T3 ES2178080T3 ES98112192T ES98112192T ES2178080T3 ES 2178080 T3 ES2178080 T3 ES 2178080T3 ES 98112192 T ES98112192 T ES 98112192T ES 98112192 T ES98112192 T ES 98112192T ES 2178080 T3 ES2178080 T3 ES 2178080T3
- Authority
- ES
- Spain
- Prior art keywords
- derivatives
- preparation
- procedure
- pirazina
- ariloxi
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
- C07D241/02—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
- C07D241/10—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
- C07D241/14—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D241/24—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
- C07D241/02—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
- C07D241/10—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
- C07D241/14—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D241/18—Oxygen or sulfur atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
- C07D241/02—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
- C07D241/10—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
- C07D241/14—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D241/20—Nitrogen atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Plural Heterocyclic Compounds (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Abstract
SE DESCRIBE UN NUEVO PROCEDIMIENTO PARA PREPARAR DERIVADOS DE ALCOXIPIRAZINA O ARILOXIPIRAZINA DE FORMULA GENERAL. ESTOS SE OBTIENEN POR REACCION DE UN DERIVADO DE GLIOXAL DE FORMULA GENERAL Y UN AMINOIMIDATO DE FORMULA GENERAL. LOS DERIVADOS DE ALCOXIPIRAZINA O ARILOXIPIRAZINA SON PRODUCTOS INTERMEDIOS BASICOS PARA LA PREPARACION DE SUSTANCIAS ACTIVAS FARMACEUTICAMENTE EFECTIVAS.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CH161597 | 1997-07-03 |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2178080T3 true ES2178080T3 (es) | 2002-12-16 |
Family
ID=4214583
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES98112192T Expired - Lifetime ES2178080T3 (es) | 1997-07-03 | 1998-07-01 | Procedimiento para la preparacion de derivados de alcoxi-o ariloxi-pirazina. |
Country Status (9)
Country | Link |
---|---|
US (3) | US6066736A (es) |
EP (1) | EP0889038B1 (es) |
JP (1) | JP4660862B2 (es) |
AT (1) | ATE218130T1 (es) |
CA (1) | CA2241933C (es) |
DE (1) | DE59804221D1 (es) |
DK (1) | DK0889038T3 (es) |
ES (1) | ES2178080T3 (es) |
PT (1) | PT889038E (es) |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2005320249A (ja) * | 2002-05-01 | 2005-11-17 | Banyu Pharmaceut Co Ltd | 2−アミノピラジン誘導体の製造方法 |
IL149499A (en) * | 2002-05-06 | 2006-10-31 | Bromine Compounds Ltd | Process for the preparation of concentrated solutions of stabilized hypobromites |
US20090142417A1 (en) * | 2002-05-06 | 2009-06-04 | Bromine Compounds Ltd. | Process for the preparation of concentrated solutions of stabilized hypobromites |
US7939042B2 (en) * | 2002-05-06 | 2011-05-10 | Bromine Compounds Ltd. | Process for the preparation of concentrated solutions of stabilized hypobromites |
Family Cites Families (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2805223A (en) * | 1955-02-14 | 1957-09-03 | American Cyanamid Co | Method of preparing 2-hydroxypyrazines |
GB922735A (en) | 1958-07-16 | 1963-04-03 | Emi Ltd | Improvements in or relating to resonant cavities |
GB922725A (en) * | 1960-07-08 | 1963-04-03 | Farmaceutici Italia | Pyrazine derivatives |
FR1366718A (fr) * | 1960-07-13 | 1964-07-17 | Farmaceutici Italia | Dérivés de pyrazine et procédés pour les préparer |
US3660400A (en) * | 1966-11-17 | 1972-05-02 | Merck & Co Inc | Lower alkyl 3-hydroxy and 3-mercaptopyrazinoates |
NL7008625A (es) * | 1969-06-25 | 1970-12-29 | ||
US3745161A (en) * | 1970-04-20 | 1973-07-10 | Merck & Co Inc | Phenyl-hydroxy-pyrazine carboxylic acids and derivatives |
US4041032A (en) * | 1974-01-16 | 1977-08-09 | Yamanouchi Pharmaceutical Co., Ltd. | Pyrazine derivatives |
JPS5283679A (en) * | 1976-01-01 | 1977-07-12 | Yamanouchi Pharmaceut Co Ltd | Pirazine derivative |
US5459266A (en) * | 1994-02-04 | 1995-10-17 | Hoechst Celanese Corporation | Substituted pyrazines |
CA2209465C (en) * | 1996-07-11 | 2008-04-29 | Lonza Ag | Process for preparing 3-alkoxy-5-alkylpyrazin-2-amines |
-
1998
- 1998-06-29 CA CA002241933A patent/CA2241933C/en not_active Expired - Fee Related
- 1998-06-29 JP JP18307598A patent/JP4660862B2/ja not_active Expired - Fee Related
- 1998-06-29 US US09/105,987 patent/US6066736A/en not_active Expired - Fee Related
- 1998-07-01 DE DE59804221T patent/DE59804221D1/de not_active Expired - Lifetime
- 1998-07-01 ES ES98112192T patent/ES2178080T3/es not_active Expired - Lifetime
- 1998-07-01 AT AT98112192T patent/ATE218130T1/de active
- 1998-07-01 EP EP98112192A patent/EP0889038B1/de not_active Expired - Lifetime
- 1998-07-01 DK DK98112192T patent/DK0889038T3/da active
- 1998-07-01 PT PT98112192T patent/PT889038E/pt unknown
-
2000
- 2000-01-28 US US09/583,096 patent/US6235905B1/en not_active Expired - Fee Related
-
2001
- 2001-02-20 US US09/785,250 patent/US6291674B2/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
CA2241933C (en) | 2008-10-07 |
US20010012894A1 (en) | 2001-08-09 |
CA2241933A1 (en) | 1999-01-03 |
DE59804221D1 (de) | 2002-07-04 |
US6291674B2 (en) | 2001-09-18 |
JP4660862B2 (ja) | 2011-03-30 |
JPH1171354A (ja) | 1999-03-16 |
EP0889038B1 (de) | 2002-05-29 |
US6066736A (en) | 2000-05-23 |
DK0889038T3 (da) | 2002-09-09 |
PT889038E (pt) | 2002-10-31 |
EP0889038A1 (de) | 1999-01-07 |
ATE218130T1 (de) | 2002-06-15 |
US6235905B1 (en) | 2001-05-22 |
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