ES2187795T3 - Derivados de anticonvulsivos utiles en el tratamiento del dolor neuropatico. - Google Patents

Derivados de anticonvulsivos utiles en el tratamiento del dolor neuropatico.

Info

Publication number
ES2187795T3
ES2187795T3 ES97932615T ES97932615T ES2187795T3 ES 2187795 T3 ES2187795 T3 ES 2187795T3 ES 97932615 T ES97932615 T ES 97932615T ES 97932615 T ES97932615 T ES 97932615T ES 2187795 T3 ES2187795 T3 ES 2187795T3
Authority
ES
Spain
Prior art keywords
treatment
rent
neuropathic pain
oxygen
convulsive
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES97932615T
Other languages
English (en)
Inventor
Richard P Shank
Kenneth Wild
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Janssen Pharmaceuticals Inc
Original Assignee
Ortho McNeil Pharmaceutical Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ortho McNeil Pharmaceutical Inc filed Critical Ortho McNeil Pharmaceutical Inc
Application granted granted Critical
Publication of ES2187795T3 publication Critical patent/ES2187795T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/18—Sulfonamides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/34—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids

Landscapes

  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurology (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Neurosurgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)

Abstract

ESTA INVENCION SE REFIERE A UN PROCEDIMIENTO PARA EL TRATAMIENTO DEL DOLOR NEUROPATICO, QUE CONSISTE EN LA ADMINISTRACION A UN MAMIFERO QUE PADECE DE DICHA DOLENCIA DE UNA DOSIS TERAPEUTICAMENTE EFICAZ DE UN COMPUESTO DE FORMULA (I). EN DICHA FORMULA (I), X REPRESENTA CH 2 U OXIGENO; R 1 REPRESENTA EL HIDROGENO O EL ALQUILO; Y R 2 , R 3 , R 4 Y R 5 REPRESENTAN SEPARADAMENTE EL HIDROGENO O ALQUILO INFERIOR Y, CUANDO X ES CH 2 , R 4 Y R 5 PUEDEN SER GRUPOS ALQUILOS UNIDOS PARA FORMAR UN CICLO BENZENO Y, CUANDO X ES OXIGENO, R 2 Y R 3 Y/O R 4 Y R 5 PUEDEN REPRESENTAR JUNTOS UN GRUPO METILENODIOXILO DE FORMULA GENERAL (II). EN LA FORMULA GENERAL (II), R 6 Y R 7 SON IDENTICOS O DIFERENTES Y REPRESENTAN EL OXIGENO, EL ALQUILO INFERIOR O EL ALQUILO Y SE UNEN PARA FORMAR UN CICLO CICLOPENTILO O CICLOHEXILO, EN PARTICULAR DEL TOPORIMATO.
ES97932615T 1996-10-08 1997-07-16 Derivados de anticonvulsivos utiles en el tratamiento del dolor neuropatico. Expired - Lifetime ES2187795T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US2768796P 1996-10-08 1996-10-08

Publications (1)

Publication Number Publication Date
ES2187795T3 true ES2187795T3 (es) 2003-06-16

Family

ID=21839205

Family Applications (1)

Application Number Title Priority Date Filing Date
ES97932615T Expired - Lifetime ES2187795T3 (es) 1996-10-08 1997-07-16 Derivados de anticonvulsivos utiles en el tratamiento del dolor neuropatico.

Country Status (23)

Country Link
EP (1) EP0932400B1 (es)
JP (1) JP4097294B2 (es)
KR (1) KR100496934B1 (es)
CN (1) CN1105559C (es)
AP (1) AP1513A (es)
AT (1) ATE226071T1 (es)
AU (1) AU725570B2 (es)
BR (1) BR9712503A (es)
CA (1) CA2267945C (es)
CZ (1) CZ296525B6 (es)
DE (1) DE69716453T2 (es)
DK (1) DK0932400T3 (es)
ES (1) ES2187795T3 (es)
HU (1) HU225031B1 (es)
IL (1) IL129276A (es)
NO (1) NO321390B1 (es)
NZ (1) NZ334981A (es)
PT (1) PT932400E (es)
RU (1) RU2175868C2 (es)
SI (1) SI0932400T1 (es)
SK (1) SK284271B6 (es)
UA (1) UA48256C2 (es)
WO (1) WO1998015270A1 (es)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE60015070T2 (de) * 1999-01-19 2006-01-05 Ortho-Mcneil Pharmaceutical, Inc. Verwendung von antikonvulsiven derivaten zur behandlung der cluster headache
AU3582600A (en) * 1999-01-21 2000-08-07 Ortho-Mcneil Pharmaceutical, Inc. Anticonvulsant derivatives useful in treating transformed migraine
WO2002043731A2 (en) * 2000-11-30 2002-06-06 University Of Florida Treatments for neurogenetic disorders, impulse control disorders, and wound healing
MY147767A (en) 2004-06-16 2013-01-31 Janssen Pharmaceutica Nv Novel sulfamate and sulfamide derivatives useful for the treatment of epilepsy and related disorders
US8497298B2 (en) 2005-12-19 2013-07-30 Janssen Pharmaceutica Nv Use of benzo-fused heterocycle sulfamide derivatives for lowering lipids and lowering blood glucose levels
US8937096B2 (en) 2005-12-19 2015-01-20 Janssen Pharmaceutica Nv Use of benzo-fused heterocyle sulfamide derivatives for the treatment of mania and bipolar disorder
US8691867B2 (en) 2005-12-19 2014-04-08 Janssen Pharmaceutica Nv Use of benzo-fused heterocycle sulfamide derivatives for the treatment of substance abuse and addiction
US8716231B2 (en) 2005-12-19 2014-05-06 Janssen Pharmaceutica Nv Use of benzo-fused heterocycle sulfamide derivatives for the treatment of pain
TW200812573A (en) 2006-05-19 2008-03-16 Janssen Pharmaceutica Nv Co-therapy for the treatment of epilepsy and related disorders
JP5912269B2 (ja) 2011-03-11 2016-04-27 ローランド株式会社 電子楽器
US8652527B1 (en) 2013-03-13 2014-02-18 Upsher-Smith Laboratories, Inc Extended-release topiramate capsules
US9101545B2 (en) 2013-03-15 2015-08-11 Upsher-Smith Laboratories, Inc. Extended-release topiramate capsules

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4513006A (en) * 1983-09-26 1985-04-23 Mcneil Lab., Inc. Anticonvulsant sulfamate derivatives
US5998380A (en) * 1995-10-13 1999-12-07 New England Medical Center Hospitals, Inc. Treatment of migraine

Also Published As

Publication number Publication date
NO321390B1 (no) 2006-05-08
PT932400E (pt) 2003-03-31
UA48256C2 (uk) 2002-08-15
IL129276A (en) 2003-04-10
NO991621D0 (no) 1999-04-06
IL129276A0 (en) 2000-02-17
HUP9904294A2 (hu) 2001-04-28
JP4097294B2 (ja) 2008-06-11
SK45499A3 (en) 2000-08-14
DE69716453T2 (de) 2003-02-27
DE69716453D1 (de) 2002-11-21
NO991621L (no) 1999-05-25
AU3602297A (en) 1998-05-05
HUP9904294A3 (en) 2001-08-28
DK0932400T3 (da) 2003-02-10
SK284271B6 (sk) 2004-12-01
AP1513A (en) 2005-12-12
KR20000048871A (ko) 2000-07-25
AU725570B2 (en) 2000-10-12
NZ334981A (en) 2000-08-25
EP0932400A1 (en) 1999-08-04
CA2267945C (en) 2005-05-17
ATE226071T1 (de) 2002-11-15
CA2267945A1 (en) 1998-04-16
CN1105559C (zh) 2003-04-16
AP9901508A0 (en) 1999-06-30
KR100496934B1 (ko) 2005-06-23
RU2175868C2 (ru) 2001-11-20
CZ296525B6 (cs) 2006-04-12
EP0932400B1 (en) 2002-10-16
CZ115799A3 (cs) 1999-09-15
BR9712503A (pt) 1999-10-19
WO1998015270A1 (en) 1998-04-16
HU225031B1 (en) 2006-05-29
SI0932400T1 (en) 2002-12-31
JP2001501643A (ja) 2001-02-06
CN1232393A (zh) 1999-10-20

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