ES2186916T3 - Derivados de isoxazolina como agentes antimicrobianos. - Google Patents

Derivados de isoxazolina como agentes antimicrobianos.

Info

Publication number
ES2186916T3
ES2186916T3 ES97937156T ES97937156T ES2186916T3 ES 2186916 T3 ES2186916 T3 ES 2186916T3 ES 97937156 T ES97937156 T ES 97937156T ES 97937156 T ES97937156 T ES 97937156T ES 2186916 T3 ES2186916 T3 ES 2186916T3
Authority
ES
Spain
Prior art keywords
antimicrobial agents
isoxazoline derivatives
isoxazoline
derivatives
national
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES97937156T
Other languages
English (en)
Spanish (es)
Inventor
Michael R Barbachyn
Richard C Thomas
Gary J Cleek
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pharmacia and Upjohn Co
Original Assignee
Pharmacia and Upjohn Co
Upjohn Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pharmacia and Upjohn Co, Upjohn Co filed Critical Pharmacia and Upjohn Co
Application granted granted Critical
Publication of ES2186916T3 publication Critical patent/ES2186916T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/10—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing aromatic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D261/00—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings
    • C07D261/02—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings
    • C07D261/04—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Plural Heterocyclic Compounds (AREA)
ES97937156T 1996-08-21 1997-08-15 Derivados de isoxazolina como agentes antimicrobianos. Expired - Lifetime ES2186916T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US2428796P 1996-08-21 1996-08-21

Publications (1)

Publication Number Publication Date
ES2186916T3 true ES2186916T3 (es) 2003-05-16

Family

ID=21819822

Family Applications (1)

Application Number Title Priority Date Filing Date
ES97937156T Expired - Lifetime ES2186916T3 (es) 1996-08-21 1997-08-15 Derivados de isoxazolina como agentes antimicrobianos.

Country Status (10)

Country Link
US (2) US5990136A (2)
EP (1) EP0920421B1 (2)
JP (1) JP2000516245A (2)
AT (1) ATE227277T1 (2)
AU (1) AU3973697A (2)
DE (1) DE69716925T2 (2)
DK (1) DK0920421T3 (2)
ES (1) ES2186916T3 (2)
PT (1) PT920421E (2)
WO (1) WO1998007708A1 (2)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9601666D0 (en) * 1996-01-27 1996-03-27 Zeneca Ltd Chemical compounds
GB9609919D0 (en) 1996-05-11 1996-07-17 Zeneca Ltd Chemical compounds
US6255304B1 (en) 1997-05-30 2001-07-03 Pharmacia & Upjohn Company Oxazolidinone antibacterial agents having a thiocarbonyl functionality
CN1138765C (zh) 1997-05-30 2004-02-18 法玛西雅厄普约翰美国公司 带有硫代羰基功能基的噁唑烷酮抗菌剂
GB9717807D0 (en) 1997-08-22 1997-10-29 Zeneca Ltd Chemical compounds
GB9717804D0 (en) 1997-08-22 1997-10-29 Zeneca Ltd Chemical compounds
GB9725244D0 (en) 1997-11-29 1998-01-28 Zeneca Ltd Chemical compounds
US6069141A (en) * 1998-02-13 2000-05-30 Pharmacia & Upjohn Company Substituted aminophenyl isoxazoline derivatives useful as antimicrobials
AU3180999A (en) * 1998-02-25 1999-09-15 Pharmacia & Upjohn Company Substituted aminomethyl isoxazoline derivatives useful as antimicrobials
TR200003595T2 (tr) 1998-06-05 2001-07-23 Astrazeneca Ab Kimyasal bileşikler
US6420349B1 (en) 1998-08-24 2002-07-16 Bristol-Myers Squibb Company Isoxazolinone antibacterial agents
TW572757B (en) * 1998-08-24 2004-01-21 Bristol Myers Squibb Co Novel isoxazolinone antibacterial agents
GB9928568D0 (en) 1999-12-03 2000-02-02 Zeneca Ltd Chemical compounds
GB0009803D0 (en) 2000-04-25 2000-06-07 Astrazeneca Ab Chemical compounds
US6465456B2 (en) 2000-06-29 2002-10-15 Bristol-Myers Squibb Company Isoxazolinone antibacterial agents
ES2256331T3 (es) 2000-12-21 2006-07-16 PHARMACIA & UPJOHN COMPANY LLC Derivados de quinolina antimicrobianos y uso de los mismos para tratar infecciones bacterianas.
CN1247511C (zh) 2000-12-26 2006-03-29 财团法人乙卯研究所 环庚三烯酚酮衍生物
EP1443930A1 (en) * 2001-10-25 2004-08-11 AstraZeneca AB Isoxazoline derivatives useful as antimicrobials
AR038536A1 (es) * 2002-02-25 2005-01-19 Upjohn Co N-aril-2-oxazolidinona-5- carboxamidas y sus derivados
US7141588B2 (en) * 2002-02-25 2006-11-28 Pfizer, Inc. N-aryl-2-oxazolidinone-5-carboxamides and their derivatives
JP2006516989A (ja) * 2003-02-07 2006-07-13 ワーナー−ランバート・カンパニー、リミテッド、ライアビリティ、カンパニー 抗菌剤として使用するための二環式環によりｎ−置換されたオキサゾリジノン誘導体
CA2515311A1 (en) * 2003-02-07 2004-08-19 Warner-Lambert Company Llc Antibacterial agents
US7304050B2 (en) * 2003-09-16 2007-12-04 Pfizer Inc. Antibacterial agents
WO2005082900A2 (en) * 2004-01-28 2005-09-09 Pharmacia & Upjohn Company Llc Oxazolidinone amidoximes as antibacterial agents
MX2007001526A (es) * 2004-08-06 2007-03-27 Pharmacia & Upjohn Co Llc Oxazolidinonas que contienen oxindoles como agentes antibacterianos.
CN101696221B (zh) * 2004-09-10 2013-05-29 先正达有限公司 作为杀真菌剂的取代异噁唑
CN103270036B (zh) * 2010-08-05 2015-11-25 佐蒂斯有限责任公司 作为抗寄生物剂的异噁唑啉衍生物
CA2822357A1 (en) 2010-12-22 2012-06-28 Abbvie Inc. Hepatitis c inhibitors and uses thereof
US9938816B2 (en) * 2012-10-03 2018-04-10 Shell Oil Company Optimizing performance of a drilling assembly
WO2021000297A1 (en) * 2019-07-03 2021-01-07 Merck Sharp & Dohme Corp. Compounds and methods of use thereof as antibacterial agents

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL137326C (2) * 1967-08-26
US4283403A (en) * 1976-06-14 1981-08-11 Eli Lilly And Company Substituted isoxazolines for control of plant phytopathogens
US4948801A (en) * 1988-07-29 1990-08-14 E. I. Du Pont De Nemours And Company Aminomethyloxooxazolidinyl arylbenzene derivatives useful as antibacterial agents
EP0673370B1 (en) * 1992-12-08 1998-01-07 PHARMACIA & UPJOHN COMPANY Tropone-substituted phenyloxazolidinone antibacterial agents
WO1995014680A1 (en) * 1993-11-26 1995-06-01 Pfizer Inc. 3-aryl-2-isoxazolines as antiinflammatory agents
DE4425612A1 (de) * 1994-07-20 1996-04-04 Bayer Ag 6-gliedrige stickstoffhaltige Heteroaryl-oxazolidinone
DE4425613A1 (de) * 1994-07-20 1996-01-25 Bayer Ag 5-gliedrige Heteroaryl-oxazolidinone
US5710159A (en) * 1996-05-09 1998-01-20 The Dupont Merck Pharmaceutical Company Integrin receptor antagonists

Also Published As

Publication number Publication date
DE69716925D1 (de) 2002-12-12
DE69716925T2 (de) 2003-09-11
WO1998007708A1 (en) 1998-02-26
US5990136A (en) 1999-11-23
EP0920421A1 (en) 1999-06-09
AU3973697A (en) 1998-03-06
EP0920421B1 (en) 2002-11-06
DK0920421T3 (da) 2003-03-10
PT920421E (pt) 2003-03-31
JP2000516245A (ja) 2000-12-05
ATE227277T1 (de) 2002-11-15
US6093736A (en) 2000-07-25

Similar Documents

Publication Publication Date Title
ES2186916T3 (es) Derivados de isoxazolina como agentes antimicrobianos.
UY26551A1 (es) " agentes antibacterianos de 3-aminoquinazolin-2,4,dionas".
DE69829846D1 (de) Antibakteriell wirksam oxazolidinone mit einer thiocarbonylfunktionalität
CO4930259A1 (es) Derivados 6,6-heterobiciclicos sustituidos y composiciones farmaceuticas que los contienen
ES2179071T3 (es) Agentes vasodilatadores perifericos que comprenden como principio activo derivados de la piperidina 4-amino n-acilada.
PA8436201A1 (es) Derivados 6,5-heterobiciclicos sustituidos
PA8451801A1 (es) Derivados de la 9-oxima eritromicina
TR199901473T2 (xx) Ha�ere �ld�r�c� 1-arilpirazoller
NO982071D0 (no) Benzoksazin-antimikrobielle midler
DE69433784D1 (de) 9-(Substituiertes Glycyl)amido-6-(substituiert)-5-hydroxy-6-deoxytetracycline
YU11997A (sh) Laktamski derivati i njihove farmaceutske kompozicije
MA27643A1 (fr) Utilisation de n-alkyl-4-methyleneamino-3-hydroxy-2-pyridones en tant qu'agents antimicrobiens
ES2183331T3 (es) Inhibidores de sulfamida-metaloproteasa.
BR9407169A (pt) Derivados de pirazol
PT768086E (pt) Tratamento de tinido utilizando agentes neuroprotectores
IT1269176B (it) Eterobicicli ad attivita' fungicida
ES2188984T3 (es) Procedimiento de enriquecimiento en r de epimeros de derivados de 16,17-acetales de derivados de 21-aciloxi-pregnano-1,4-dieno-11-beta, 16alfa-triol-3,20-dionas.
BR0010982A (pt) Novas oxazolidinonas bicìclicas como agentes antibacterianos
ES2178765T3 (es) Nuevos derivados de 1,7,7-trimetil-biciclo (2.2.1) heptano.
AR030537A1 (es) Acidos quinolincarboxilicos y naftiridincarboxilico antibacterianos
AR025379A1 (es) 9a-azalidas con actividad antibacteriana.
DK1073447T3 (da) N1-modificerede glycopeptider
CY1105598T1 (el) Μεθοδοι για την παρασκευη αντιβακτηριακων παραγοντων τυπου carbapenem
PT1268475E (pt) Novos agentes bacterianos de benzosultam-oxazolidinona
TR200100222T2 (tr) Ürokinaz önleyicileri olarak izokinolinler