ES2185188T3 - Composiciones farmaceuticas de prostaglandinas. - Google Patents

Composiciones farmaceuticas de prostaglandinas.

Info

Publication number
ES2185188T3
ES2185188T3 ES98934967T ES98934967T ES2185188T3 ES 2185188 T3 ES2185188 T3 ES 2185188T3 ES 98934967 T ES98934967 T ES 98934967T ES 98934967 T ES98934967 T ES 98934967T ES 2185188 T3 ES2185188 T3 ES 2185188T3
Authority
ES
Spain
Prior art keywords
prostaglandinas
pharmaceutical compositions
sub
compounds
general formula
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES98934967T
Other languages
English (en)
Spanish (es)
Inventor
Soldato Piero Del
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Nicox SA
Original Assignee
Nicox SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nicox SA filed Critical Nicox SA
Application granted granted Critical
Publication of ES2185188T3 publication Critical patent/ES2185188T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C405/00Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/557Eicosanoids, e.g. leukotrienes or prostaglandins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • A61P15/10Drugs for genital or sexual disorders; Contraceptives for impotence
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • A61P27/06Antiglaucoma agents or miotics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Gynecology & Obstetrics (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Food Preservation Except Freezing, Refrigeration, And Drying (AREA)
ES98934967T 1997-06-19 1998-06-17 Composiciones farmaceuticas de prostaglandinas. Expired - Lifetime ES2185188T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT97MI001440A IT1292377B1 (it) 1997-06-19 1997-06-19 Composizioni farmaceutiche a base di prostaglandine

Publications (1)

Publication Number Publication Date
ES2185188T3 true ES2185188T3 (es) 2003-04-16

Family

ID=11377397

Family Applications (1)

Application Number Title Priority Date Filing Date
ES98934967T Expired - Lifetime ES2185188T3 (es) 1997-06-19 1998-06-17 Composiciones farmaceuticas de prostaglandinas.

Country Status (19)

Country Link
US (1) US6211233B1 (enExample)
EP (1) EP0989972B1 (enExample)
JP (1) JP4394170B2 (enExample)
KR (1) KR20010013625A (enExample)
CN (1) CN1260778A (enExample)
AT (1) ATE225771T1 (enExample)
AU (1) AU740683B2 (enExample)
BR (1) BR9810163B1 (enExample)
CA (1) CA2292836C (enExample)
DE (1) DE69808619T2 (enExample)
DK (1) DK0989972T3 (enExample)
ES (1) ES2185188T3 (enExample)
HU (1) HUP0004071A3 (enExample)
IL (1) IL132690A (enExample)
IT (1) IT1292377B1 (enExample)
PT (1) PT989972E (enExample)
RU (1) RU2000100807A (enExample)
SI (1) SI0989972T1 (enExample)
WO (1) WO1998058910A1 (enExample)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9801398D0 (en) 1998-01-22 1998-03-18 Anggard Erik E Chemical compounds
AU3713600A (en) 1999-03-01 2000-09-21 Nitromed, Inc. Nitrosated and nitrosylated prostaglandins, compositions and metods of use
IT1311923B1 (it) 1999-04-13 2002-03-20 Nicox Sa Composti farmaceutici.
IT1319201B1 (it) * 2000-10-12 2003-09-26 Nicox Sa Farmaci per il diabete.
AU2002243795A1 (en) * 2001-01-30 2002-08-12 Pharmaceutical Research Corporation Use of prostaglandin analogs for treatment of cardiac conditions
GB0111872D0 (en) * 2001-05-15 2001-07-04 Northwick Park Inst For Medica Therapeutic agents and methods
US7968605B2 (en) * 2002-02-04 2011-06-28 ALFAMA—Investigação e Desenvolvimento de Produtos Farmacêuticos, Lda. Methods for treating inflammatory disease by administering aldehydes and derivatives thereof
EP2042181A1 (en) * 2002-02-04 2009-04-01 ALFAMA-Investigacao e Desenvolvimento de Produtos Farmaceuticos Lda. Use of co-releasing compounds for the manufacture of a medicament for the treatment of inflammatory diseases
US20080026984A1 (en) * 2002-02-04 2008-01-31 Alfama - Investigacao E Desenvolvimento De Productos Farmaceuticos Lda Methods for treating inflammatory disease by administering aldehydes and derivatives thereof
AU2003278565A1 (en) * 2002-10-25 2004-05-13 Yissum Research Development Company Of The Hebrew University Of Jerusalem Steroid compounds comprising superoxide dismutase mimic groups and nitric oxide donor groups, and their use in the preparation of medicaments
GB2395432B (en) * 2002-11-20 2005-09-14 Northwick Park Inst For Medica Therapeutic delivery of carbon monoxide to extracorporeal and isolated organs
ES2767136T3 (es) 2004-01-05 2020-06-16 Nicox Sa Derivados de prostaglandinas
JP2009500315A (ja) * 2005-06-29 2009-01-08 ファイザー・インク フルオロプロスタグランジンのニトロ誘導体
EP1899295A2 (en) * 2005-06-29 2008-03-19 Pfizer, Inc. Prostaglandin derivatives
WO2007073226A1 (en) * 2005-12-20 2007-06-28 Alfama - Investigação E Desenvolvimento De Produtos Farmacêuticos Lda Method for treating a mammal by administration of a compound having the ability to release co
GB0601394D0 (en) 2006-01-24 2006-03-01 Hemocorm Ltd Therapeutic delivery of carbon monoxide
CA2647859C (en) * 2006-03-29 2016-01-05 Nitromed, Inc. Nitric oxide enhancing prostaglandin compounds, compositions and methods of use
US8041859B2 (en) * 2007-11-05 2011-10-18 Honywell International Inc. Apparatus and method for connectivity in networks capable of non-disruptively disconnecting peripheral devices
US9163044B2 (en) 2011-04-19 2015-10-20 Alfama, Inc. Carbon monoxide releasing molecules and uses thereof
WO2013013179A1 (en) 2011-07-21 2013-01-24 Alfama, Inc. Ruthenium carbon monoxide releasing molecules and uses thereof
WO2014111957A1 (en) 2013-01-21 2014-07-24 Apparao Satyam Nitric oxide releasing prodrugs of therapeutic agents
CN113943266A (zh) * 2021-11-18 2022-01-18 广州楷石医药有限公司 一种氧化氮供体型贝前列素类衍生物及其药物组合物和用途
CN116178233A (zh) * 2023-02-27 2023-05-30 广州楷石生物科技有限公司 伊洛前列素一氧化氮供体药物

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3371199D1 (en) * 1982-08-24 1987-06-04 Teijin Ltd Novel 6-nitroprostaglandin derivatives, process for production thereof, and use thereof
SE463851B (sv) 1988-09-02 1991-02-04 Amsu Ltd Komposition foer behandling av erektil dysfunktion via uretra
IT1243367B (it) 1990-07-26 1994-06-10 Italfarmaco Spa Derivati acidi benzoici sostituiti ad attivita' cardiovascolare
US5352708A (en) 1992-09-21 1994-10-04 Allergan, Inc. Non-acidic cyclopentane heptanoic acid, 2-cycloalkyl or arylalkyl derivatives as therapeutic agents
US5328933A (en) * 1992-10-28 1994-07-12 Allergan, Inc. Cyclopentane heptenylnitro and heptanylnitro-2-aliphatic or aryl aliphatic derivatives and homologues
JP4043046B2 (ja) * 1994-05-10 2008-02-06 ニコックス エス エイ 消炎、鎮痛および抗血栓活性を有するニトロ化合物およびそれらの組成物
US5625083A (en) * 1995-06-02 1997-04-29 Bezuglov; Vladimir V. Dinitroglycerol esters of unsaturated fatty acids and prostaglandins

Also Published As

Publication number Publication date
PT989972E (pt) 2003-02-28
JP4394170B2 (ja) 2010-01-06
KR20010013625A (ko) 2001-02-26
HUP0004071A2 (hu) 2001-04-28
DE69808619D1 (de) 2002-11-14
BR9810163B1 (pt) 2009-01-13
ATE225771T1 (de) 2002-10-15
CN1260778A (zh) 2000-07-19
CA2292836C (en) 2010-03-02
CA2292836A1 (en) 1998-12-30
WO1998058910A1 (en) 1998-12-30
IL132690A (en) 2004-06-01
ITMI971440A1 (it) 1998-12-19
AU740683B2 (en) 2001-11-08
US6211233B1 (en) 2001-04-03
DE69808619T2 (de) 2003-06-12
BR9810163A (pt) 2000-08-08
DK0989972T3 (da) 2003-02-10
EP0989972A1 (en) 2000-04-05
ITMI971440A0 (enExample) 1997-06-19
AU8438698A (en) 1999-01-04
IT1292377B1 (it) 1999-02-08
JP2002506440A (ja) 2002-02-26
RU2000100807A (ru) 2002-02-27
HUP0004071A3 (en) 2002-12-28
IL132690A0 (en) 2001-03-19
EP0989972B1 (en) 2002-10-09
SI0989972T1 (en) 2003-04-30

Similar Documents

Publication Publication Date Title
DK0989972T3 (da) Farmaceutiske prostaglandinsammensætninger
ES2186013T3 (es) Nitratos organicos con actividad antitrombotica.
EA200400815A1 (ru) Контролируемый синтез зипразидона и его композиции
ES2064700T3 (es) Derivados de adenosina con actividad farmaceutica como antihipertensivos.
TR199902368T2 (xx) S�lfonamid t�revleri.
CO5050332A1 (es) Composiciones fungicidas que comprenden 2-metoxibenzofenonas
ATE226193T1 (de) Substituierte zyklische amine als metalloproteaseinhibitoren
ATE469136T1 (de) Inhibitoren von 11-beta- hydroxysteroiddehydrogenase typ 1
PA8423701A1 (es) Nuevos plaguicidas
FI20030162A7 (fi) Uusia yhdisteitä
ES2169112T3 (es) Nuevas imidazolidinas sustituidas con un heterociclo, su procedimiento de preparacion, y sus productos intermedios, su aplicacion como medicamentos y composiciones farmaceuticas que los contienen.
IL107870A0 (en) Pharmaceutical compositions having antidepressant activity comprising pramipexol
SE9901077D0 (sv) Novel use
DE69815302D1 (de) Glaszusammensetzung zur vermeidung der alkali-kiesel-kieselsäure reaktion
EA200400708A1 (ru) Ингибиторы 11-бета-гидроксистероиддегидрогеназы типа 1
ES2163239T3 (es) Nuevos derivados cromenicos, su procedimiento de preparacion y las composiciones farmaceuticas que los contienen.
ES2194097T3 (es) Composiciones de fosfolipidos modificados con silicona.
BG103789A (en) Fungicidal compositions
ATE406431T1 (de) Parfümierte waschmitteltablette
BR9809643A (pt) Compostos heterocìclicos, seu processo de preparo e as composições farmacêuticas que os contêm
BR0017044A (pt) Benzoilciclohexandionas substituìdas para uso como herbicidas
DK0977871T3 (da) Neurotrypsin
BR9801448A (pt) Compostos heterocìclicos, processo para sua preparação e composições farmacêuticas contendo os mesmos.
DE59808166D1 (de) Verwendung von 2-methyl-thiazolidin-2,4-dicarbonsäure als mukolytikum
AR004476A1 (es) Compuestos biciclicos, su preparacion y su utilizacion en composiciones farmaceuticas