ES2163239T3 - Nuevos derivados cromenicos, su procedimiento de preparacion y las composiciones farmaceuticas que los contienen. - Google Patents

Nuevos derivados cromenicos, su procedimiento de preparacion y las composiciones farmaceuticas que los contienen.

Info

Publication number
ES2163239T3
ES2163239T3 ES98401541T ES98401541T ES2163239T3 ES 2163239 T3 ES2163239 T3 ES 2163239T3 ES 98401541 T ES98401541 T ES 98401541T ES 98401541 T ES98401541 T ES 98401541T ES 2163239 T3 ES2163239 T3 ES 2163239T3
Authority
ES
Spain
Prior art keywords
equal
group
chromenic
derivatives
new
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES98401541T
Other languages
English (en)
Inventor
Gilbert Lavielle
Thierry Dubuffet
Patrick Hautefaye
Francoise Lejeune
Mark Millan
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
ADIR SARL
Original Assignee
ADIR SARL
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ADIR SARL filed Critical ADIR SARL
Application granted granted Critical
Publication of ES2163239T3 publication Critical patent/ES2163239T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Anesthesiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyrane Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

LA INVENCION SE REFIERE A LOS COMPUESTOS DE FORMULA (I): EN LA QUE . M ES UN NUMERO ENTERO SUPERIOR O IGUAL A O E INFERIOR O IGUAL A 3 . N ES UN NUMERO ENTERO SUPERIOR O IGUAL A 0 E INFERIOR O IGUAL A 3, Y M+N ES SUPERIOR O IGUAL A 2 E INFERIOR O IGUAL A 3, . P ES UN NUMERO ENTERO SUPERIOR O IGUAL A 1 E INFERIOR O IGUAL A 6, X REPRESENTA UN GRUPO CIANO, O UN GRUPO -CO-NR 4 R 5 , SIENDO ELEGIDOS R 4 Y R 5 ENTRE HIDROGENO, ALQUILO (C 1 -C 6 ) LINEAL O RAMIFICADO, CICLOALQUILO (C 3 C 7 ), ARILO, . R 1 Y R 2 RE PRESENTAN INDEPENDIENTEMENTE UN ATOMO DE HIDROGENO O UN GRUPO ALQUILO (C 1 -C 6 ) LINEAL O RAMIFICADO, . R 3 REPRESENTA UN ATOMO DE HIDROGENO, UN GRUPO FENILO, NAFTILO, HETEROARILO EVENTUALMENTE SUSTITUIDOS, O UN GRUPO ARILOXI O ARILTIO (SIEMPRE QUE EN ESTE CASO A REPRESENTE UN ENLACE SI ), O UN GRUPO ARILO O HETEROARILO SUSTITUIDO POR UN GRUPO A''-CY, SIENDO A'' Y CY TAL COMO SE DEFINEN EN LA DESCRIPCION. MEDICAMENTOS.
ES98401541T 1997-06-24 1998-06-23 Nuevos derivados cromenicos, su procedimiento de preparacion y las composiciones farmaceuticas que los contienen. Expired - Lifetime ES2163239T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9707839A FR2764890B1 (fr) 1997-06-24 1997-06-24 Nouveaux derives chromeniques, leur procede de preparation et les compositions pharmaceutiques qui les contiennent

Publications (1)

Publication Number Publication Date
ES2163239T3 true ES2163239T3 (es) 2002-01-16

Family

ID=9508333

Family Applications (1)

Application Number Title Priority Date Filing Date
ES98401541T Expired - Lifetime ES2163239T3 (es) 1997-06-24 1998-06-23 Nuevos derivados cromenicos, su procedimiento de preparacion y las composiciones farmaceuticas que los contienen.

Country Status (19)

Country Link
US (3) US6090837A (es)
EP (1) EP0887350B1 (es)
JP (1) JP4065604B2 (es)
CN (1) CN1100057C (es)
AT (1) ATE204578T1 (es)
AU (1) AU735062B2 (es)
BR (1) BR9802212A (es)
CA (1) CA2242015C (es)
DE (1) DE69801400T2 (es)
DK (1) DK0887350T3 (es)
ES (1) ES2163239T3 (es)
FR (1) FR2764890B1 (es)
GR (1) GR3037038T3 (es)
HU (1) HU222728B1 (es)
NO (1) NO323575B1 (es)
NZ (1) NZ330787A (es)
PL (1) PL192783B1 (es)
PT (1) PT887350E (es)
ZA (1) ZA985501B (es)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2764890B1 (fr) * 1997-06-24 1999-08-27 Adir Nouveaux derives chromeniques, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
AR022230A1 (es) * 1999-01-12 2002-09-04 Abbott Gmbh & Co Kg Compuestos de triazol, composicion farmaceutica que los comprende y uso de los mismos para preparar dicha composicion
US20040077605A1 (en) * 2001-06-20 2004-04-22 Salvati Mark E. Fused heterocyclic succinimide compounds and analogs thereof, modulators of nuclear hormone receptor function
EP1854798A3 (en) * 2000-09-19 2007-11-28 Bristol-Myers Squibb Company Fused heterocyclic succinimide compounds and analogs thereof, modulators of nuclear hormone receptor function
US20040087548A1 (en) 2001-02-27 2004-05-06 Salvati Mark E. Fused cyclic succinimide compounds and analogs thereof, modulators of nuclear hormone receptor function
FR2823752B1 (fr) * 2001-04-18 2004-10-22 Servier Lab Nouveaux derives de pyrimidin-4-ones, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
TWI263640B (en) * 2001-12-19 2006-10-11 Bristol Myers Squibb Co Fused heterocyclic succinimide compounds and analogs thereof, modulators of nuclear hormone receptor function
HUP0500096A3 (en) * 2001-12-19 2012-08-28 Bristol Myers Squibb Co Fused heterocyclic compounds and analogs thereof: modulators of nuclear hormone receptor function, process for producing them and pharmaceutical compositions containing them
TW200400963A (en) 2002-05-21 2004-01-16 Wyeth Corp R-enantiomers of pyranoindole derivatives and the use thereof for the treatment of hepatitis C virus infection or disease
TW200400818A (en) 2002-05-21 2004-01-16 Wyeth Corp Method for the use of pyranoindole derivatives to treat infection with hepatitis C virus
US7765162B2 (en) * 2002-10-07 2010-07-27 Mastercard International Incorporated Method and system for conducting off-line and on-line pre-authorized payment transactions
DE102005005397B4 (de) * 2005-02-05 2008-08-21 Lts Lohmann Therapie-Systeme Ag Isolierung von N-Butylbenzolsulfonamid, Synthese von Benzolsulfonamid-Derivaten sowie Verwendung von N-Butylbenzolsulfonamid und Benzolsulfonamid-Derivaten zur Behandlung der benignen Prostatahyperplasie und/oder des Prostatakarzinoms
AU2007216994A1 (en) * 2006-02-21 2007-08-30 Purdue Research Foundation Trans-fused chromenoisoquinolines, synthesis and methods for use
US9359303B2 (en) 2009-04-21 2016-06-07 Purdue Research Foundation Octahydrobenzoisoquinoline modulators of dopamine receptors and uses therefor
FR2948372B1 (fr) * 2009-07-21 2011-07-22 Servier Lab Nouveaux derives chromeniques, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
CN111647003B (zh) * 2020-06-08 2022-06-21 中国科学院昆明植物研究所 三环氧六氢色酮a及其药物组合物和其应用

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2722194B1 (fr) * 1994-07-06 1996-08-23 Adir Nouveaux derives de benzopyrane, leur procede de preparation et les compositions pharmacuetiques qui les contiennent
GB9612153D0 (en) * 1996-06-11 1996-08-14 Smithkline Beecham Plc Compounds
FR2764890B1 (fr) * 1997-06-24 1999-08-27 Adir Nouveaux derives chromeniques, leur procede de preparation et les compositions pharmaceutiques qui les contiennent

Also Published As

Publication number Publication date
FR2764890A1 (fr) 1998-12-24
DE69801400D1 (de) 2001-09-27
HUP9801423A2 (hu) 1999-03-29
NO323575B1 (no) 2007-06-11
FR2764890B1 (fr) 1999-08-27
ZA985501B (en) 1999-01-20
HK1016987A1 (en) 1999-11-12
AU7314098A (en) 1999-01-07
CN1203235A (zh) 1998-12-30
CN1100057C (zh) 2003-01-29
US6090837A (en) 2000-07-18
ATE204578T1 (de) 2001-09-15
US6326377B1 (en) 2001-12-04
HU9801423D0 (en) 1998-08-28
EP0887350B1 (fr) 2001-08-22
AU735062B2 (en) 2001-06-28
GR3037038T3 (en) 2002-01-31
JPH1171376A (ja) 1999-03-16
DE69801400T2 (de) 2002-05-16
CA2242015C (fr) 2005-01-04
US6365605B1 (en) 2002-04-02
HUP9801423A3 (en) 1999-04-28
HU222728B1 (hu) 2003-09-29
JP4065604B2 (ja) 2008-03-26
DK0887350T3 (da) 2001-10-08
EP0887350A1 (fr) 1998-12-30
CA2242015A1 (fr) 1998-12-24
PT887350E (pt) 2001-11-30
NO982921L (no) 1998-12-28
PL327002A1 (en) 1999-01-04
NO982921D0 (no) 1998-06-23
NZ330787A (en) 1999-04-29
BR9802212A (pt) 1999-05-25
PL192783B1 (pl) 2006-12-29

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