ES2177581T3 - Uso de compuestos de piperidina en el tratamiento de esquizofrenia. - Google Patents
Uso de compuestos de piperidina en el tratamiento de esquizofrenia.Info
- Publication number
- ES2177581T3 ES2177581T3 ES94924708T ES94924708T ES2177581T3 ES 2177581 T3 ES2177581 T3 ES 2177581T3 ES 94924708 T ES94924708 T ES 94924708T ES 94924708 T ES94924708 T ES 94924708T ES 2177581 T3 ES2177581 T3 ES 2177581T3
- Authority
- ES
- Spain
- Prior art keywords
- schizophrenia
- treatment
- piperidine compounds
- mammal
- sulphur
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Abstract
LA PRESENTE INVENCION SE REFIERE A UN NUEVO METODO PARA TRATAR A UN MAMIFERO QUE SUFRA O SEA SUSCEPTIBLE A LA ESQUIZOFRENIA Y A ENFERMEDADES DE FORMA ESQUIZOFRENICA QUE COMPRENDE LA ADMINISTRACION A DICHO MAMIFERO DE UNA CANTIDAD EFECTIVA DE UN COMPUESTO DE LA FORMULA (I), EN LA QUE Z1 ES OXIGENO O AZUFRE.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US10930093A | 1993-08-19 | 1993-08-19 |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2177581T3 true ES2177581T3 (es) | 2002-12-16 |
Family
ID=22326932
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES94924708T Expired - Lifetime ES2177581T3 (es) | 1993-08-19 | 1994-08-15 | Uso de compuestos de piperidina en el tratamiento de esquizofrenia. |
Country Status (23)
Country | Link |
---|---|
EP (1) | EP0734259B1 (es) |
JP (1) | JP3126736B2 (es) |
KR (1) | KR100360575B1 (es) |
CN (1) | CN1087936C (es) |
AT (1) | ATE218864T1 (es) |
AU (1) | AU701292B2 (es) |
CA (1) | CA2169839C (es) |
CZ (1) | CZ285030B6 (es) |
DE (1) | DE69430816T2 (es) |
DK (1) | DK0734259T3 (es) |
ES (1) | ES2177581T3 (es) |
FI (2) | FI960747A (es) |
HU (1) | HU221729B1 (es) |
IL (1) | IL110708A (es) |
NO (1) | NO312706B1 (es) |
NZ (2) | NZ336597A (es) |
PT (1) | PT734259E (es) |
RU (1) | RU2191580C2 (es) |
SG (1) | SG55071A1 (es) |
TW (1) | TW442284B (es) |
UA (1) | UA63876C2 (es) |
WO (1) | WO1995005174A1 (es) |
ZA (1) | ZA946324B (es) |
Families Citing this family (24)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5998404A (en) * | 1994-10-24 | 1999-12-07 | Eli Lilly And Company | Heterocyclic compounds and their use |
US5821371A (en) * | 1994-10-24 | 1998-10-13 | Eli Lilly And Comany | Heterocyclic compounds and their preparation and use |
US5605908A (en) * | 1994-10-24 | 1997-02-25 | Eli Lilly And Company | Heterocyclic compounds and their use |
US5726193A (en) * | 1994-10-31 | 1998-03-10 | Eli Lilly And Company | Method for treating anxiety |
US5574028A (en) * | 1994-10-31 | 1996-11-12 | Eli Lilly And Company | Method for treating anxiety |
US5488056A (en) * | 1994-10-31 | 1996-01-30 | Eli Lilly And Company | Method for treating anxiety |
PT709094E (pt) * | 1994-10-31 | 2000-08-31 | Lilly Co Eli | Metodo para o tratamento da ansiedade |
US5565475A (en) * | 1994-11-08 | 1996-10-15 | Muhlhauser; Mark A. | Method of treating urinary bladder dysfunctions with 3-tetrahydropyridine derivatives |
US5852037A (en) * | 1995-11-13 | 1998-12-22 | Eli Lilly And Company | Method for treating anxiety |
US5763457A (en) * | 1995-11-13 | 1998-06-09 | Eli Lilly And Company | Method for treating anxiety |
EP0821956A1 (en) * | 1996-08-01 | 1998-02-04 | Eli Lilly And Company | Method for treating disruptive behavior disorders |
US6043258A (en) * | 1996-08-01 | 2000-03-28 | Eli Lilly And Company | Method for treating disruptive behavior disorders with xanomeline |
EP0821957A3 (en) * | 1996-08-01 | 1998-04-22 | Eli Lilly And Company | Use of 3-(4-hexyloxy-1,2,5-thiadiazol-3-yl)-1,2,5,6-tetrahydro-1-methylpyridine (xanomeline) for treating substance abuse |
EP0821959A3 (en) * | 1996-08-01 | 1998-09-16 | Eli Lilly And Company | Use of 3-(4-hexyloxy-1,2,5-thiadiazol-3-yl)-1,2,5,6-tetrahydro-1-methylpyridine for treating nicotine withdrawal |
US6117890A (en) * | 1996-08-01 | 2000-09-12 | Eli Lilly And Company | Method for treating bipolar disorder |
EP0821954A1 (en) * | 1996-08-01 | 1998-02-04 | Eli Lilly And Company | Method for treating mental retardation |
US6090829A (en) * | 1996-08-01 | 2000-07-18 | Eli Lilly And Company | Method for treating excessive aggression |
EP0821958A3 (en) * | 1996-08-01 | 1998-07-08 | Eli Lilly And Company | Use of 3-(4-hexyloxy-1,2,5-thiadiazol-3-yl)-1,2,5,6-tetrahydro-1-methylpyridine (xanomeline) for treating excessive aggression |
PT821955E (pt) * | 1996-08-01 | 2002-07-31 | Lilly Co Eli | Uso de 3-(4-hexiloxi-1,2,5-tiadiazol-3-il)-1,2,5,6-tetrahidro-1-metilpiridina (xanomelina) para o tratamento da doenca bipolar |
DE69825605T2 (de) | 1997-05-29 | 2005-09-15 | H. Lundbeck A/S | Behandlung der schizophrenie und der psychose |
US6034108A (en) * | 1997-07-28 | 2000-03-07 | Eli Lilly And Company | Method for treating mental retardation |
PL3061821T3 (pl) | 2009-07-22 | 2020-01-31 | PureTech Health LLC | Kompozycje do leczenia zaburzeń łagodzonych przez aktywację receptora muskarynowego |
EA202190356A1 (ru) | 2018-09-28 | 2021-08-13 | Каруна Терапеутикс, Инк. | Композиции и способы лечения расстройств, ослабляемых активацией мускариновых рецепторов |
WO2021097427A1 (en) | 2019-11-15 | 2021-05-20 | Karuna Therapeutics, Inc. | Xanomeline derivatives and methods for treating neurological disorders |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
NZ225999A (en) * | 1987-09-10 | 1992-04-28 | Merck Sharp & Dohme | Azacyclic- or azabicyclic-substituted thiadiazole derivatives and pharmaceutical compositions |
US5043345A (en) * | 1989-02-22 | 1991-08-27 | Novo Nordisk A/S | Piperidine compounds and their preparation and use |
DK198490D0 (da) * | 1990-08-21 | 1990-08-21 | Novo Nordisk As | Heterocykliske forbindelser, deres fremstilling og anvendelse |
DK198390D0 (da) * | 1990-08-21 | 1990-08-21 | Novo Nordisk As | Heterocykliske forbindelser, deres fremstilling og anvendelse |
-
1994
- 1994-08-15 UA UA96020584A patent/UA63876C2/uk unknown
- 1994-08-15 HU HU9600364A patent/HU221729B1/hu not_active IP Right Cessation
- 1994-08-15 JP JP07506691A patent/JP3126736B2/ja not_active Expired - Lifetime
- 1994-08-15 DE DE69430816T patent/DE69430816T2/de not_active Expired - Lifetime
- 1994-08-15 DK DK94924708T patent/DK0734259T3/da active
- 1994-08-15 KR KR1019960700806A patent/KR100360575B1/ko not_active IP Right Cessation
- 1994-08-15 NZ NZ336597A patent/NZ336597A/en unknown
- 1994-08-15 AT AT94924708T patent/ATE218864T1/de not_active IP Right Cessation
- 1994-08-15 AU AU74902/94A patent/AU701292B2/en not_active Ceased
- 1994-08-15 CZ CZ96426A patent/CZ285030B6/cs not_active IP Right Cessation
- 1994-08-15 CN CN94193733A patent/CN1087936C/zh not_active Expired - Fee Related
- 1994-08-15 RU RU96105388/14A patent/RU2191580C2/ru not_active IP Right Cessation
- 1994-08-15 ES ES94924708T patent/ES2177581T3/es not_active Expired - Lifetime
- 1994-08-15 SG SG1996004738A patent/SG55071A1/en unknown
- 1994-08-15 PT PT94924708T patent/PT734259E/pt unknown
- 1994-08-15 WO PCT/DK1994/000305 patent/WO1995005174A1/en active Application Filing
- 1994-08-15 CA CA002169839A patent/CA2169839C/en not_active Expired - Fee Related
- 1994-08-15 EP EP94924708A patent/EP0734259B1/en not_active Expired - Lifetime
- 1994-08-15 NZ NZ271311A patent/NZ271311A/en not_active IP Right Cessation
- 1994-08-18 IL IL11070894A patent/IL110708A/en not_active IP Right Cessation
- 1994-08-19 ZA ZA946324A patent/ZA946324B/xx unknown
-
1995
- 1995-02-15 TW TW084101387A patent/TW442284B/zh not_active IP Right Cessation
-
1996
- 1996-02-16 NO NO19960619A patent/NO312706B1/no not_active IP Right Cessation
- 1996-02-19 FI FI960747A patent/FI960747A/fi not_active Application Discontinuation
-
2005
- 2005-04-29 FI FI20050461A patent/FI20050461A/fi not_active Application Discontinuation
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