ATE213413T1 - Verwendung von 3-(4-hexyloxy-1,2,5-thiadiazol-3- yl)-1,2,5,6-tetrahydro-1-methylpyridin (xanomelin) zur behandlung von bipolaren störungen - Google Patents

Verwendung von 3-(4-hexyloxy-1,2,5-thiadiazol-3- yl)-1,2,5,6-tetrahydro-1-methylpyridin (xanomelin) zur behandlung von bipolaren störungen

Info

Publication number
ATE213413T1
ATE213413T1 AT97305585T AT97305585T ATE213413T1 AT E213413 T1 ATE213413 T1 AT E213413T1 AT 97305585 T AT97305585 T AT 97305585T AT 97305585 T AT97305585 T AT 97305585T AT E213413 T1 ATE213413 T1 AT E213413T1
Authority
AT
Austria
Prior art keywords
xanomeline
methylpyridine
hexyloxy
thiadiazole
tetrahydro
Prior art date
Application number
AT97305585T
Other languages
English (en)
Inventor
Franklin Porter Bymaster
Harlan Edgar Shannon
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Application granted granted Critical
Publication of ATE213413T1 publication Critical patent/ATE213413T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants

Landscapes

  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Electrical Discharge Machining, Electrochemical Machining, And Combined Machining (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Medicinal Preparation (AREA)
  • Nonmetallic Welding Materials (AREA)
  • Steroid Compounds (AREA)
  • Processing Of Solid Wastes (AREA)
  • Press Drives And Press Lines (AREA)
  • Electrolytic Production Of Non-Metals, Compounds, Apparatuses Therefor (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
AT97305585T 1996-08-01 1997-07-25 Verwendung von 3-(4-hexyloxy-1,2,5-thiadiazol-3- yl)-1,2,5,6-tetrahydro-1-methylpyridin (xanomelin) zur behandlung von bipolaren störungen ATE213413T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US2290096P 1996-08-01 1996-08-01

Publications (1)

Publication Number Publication Date
ATE213413T1 true ATE213413T1 (de) 2002-03-15

Family

ID=21812011

Family Applications (1)

Application Number Title Priority Date Filing Date
AT97305585T ATE213413T1 (de) 1996-08-01 1997-07-25 Verwendung von 3-(4-hexyloxy-1,2,5-thiadiazol-3- yl)-1,2,5,6-tetrahydro-1-methylpyridin (xanomelin) zur behandlung von bipolaren störungen

Country Status (19)

Country Link
EP (1) EP0821955B1 (de)
JP (1) JP2000515547A (de)
KR (1) KR20000029647A (de)
CN (1) CN1226165A (de)
AT (1) ATE213413T1 (de)
AU (1) AU716972B2 (de)
BR (1) BR9710901A (de)
CA (1) CA2261802C (de)
CZ (1) CZ27299A3 (de)
DE (1) DE69710526T2 (de)
DK (1) DK0821955T3 (de)
EA (1) EA199900174A1 (de)
ES (1) ES2171838T3 (de)
HU (1) HUP9904578A2 (de)
IL (1) IL128280A0 (de)
NO (1) NO990436D0 (de)
PL (1) PL331407A1 (de)
PT (1) PT821955E (de)
WO (1) WO1998005324A1 (de)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3061821B1 (de) 2009-07-22 2019-07-10 Puretech Health LLC Zusammensetzungen zur behandlung von durch muscarinrezeptoraktivierung gelinderten leiden
US10265311B2 (en) 2009-07-22 2019-04-23 PureTech Health LLC Methods and compositions for treatment of disorders ameliorated by muscarinic receptor activation
WO2014078568A1 (en) 2012-11-14 2014-05-22 The Johns Hopkins University Methods and compositions for treating schizophrenia
IL281809B (en) 2018-09-28 2022-09-01 Karuna Therapeutics Inc Compositions and methods for the treatment of diseases improved by the activation of muscarinic receptors
CN111430027B (zh) * 2020-03-18 2023-04-28 浙江大学 基于肠道微生物的双相情感障碍生物标志物及其筛选应用

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5043345A (en) * 1989-02-22 1991-08-27 Novo Nordisk A/S Piperidine compounds and their preparation and use
US5376668A (en) * 1990-08-21 1994-12-27 Novo Nordisk A/S Heterocyclic compounds
DK0734259T3 (da) * 1993-08-19 2002-09-30 Novo Nordisk As Antipsykotisk fremgangsmåde
US5821370A (en) * 1994-10-24 1998-10-13 Eli Lilly And Company Heterocyclic compounds and their preparation and use
WO1996013167A1 (en) * 1994-10-31 1996-05-09 Eli Lilly And Company Method for treating anxiety
US5488056A (en) * 1994-10-31 1996-01-30 Eli Lilly And Company Method for treating anxiety

Also Published As

Publication number Publication date
AU4046897A (en) 1998-02-25
CN1226165A (zh) 1999-08-18
CA2261802C (en) 2006-11-07
BR9710901A (pt) 1999-08-17
JP2000515547A (ja) 2000-11-21
EA199900174A1 (ru) 1999-08-26
EP0821955A2 (de) 1998-02-04
EP0821955A3 (de) 1998-04-22
IL128280A0 (en) 1999-11-30
AU716972B2 (en) 2000-03-09
DE69710526T2 (de) 2002-10-02
PL331407A1 (en) 1999-07-19
DK0821955T3 (da) 2002-03-18
CA2261802A1 (en) 1998-02-12
CZ27299A3 (cs) 1999-08-11
EP0821955B1 (de) 2002-02-20
PT821955E (pt) 2002-07-31
NO990436L (no) 1999-01-29
KR20000029647A (ko) 2000-05-25
WO1998005324A1 (en) 1998-02-12
ES2171838T3 (es) 2002-09-16
HUP9904578A2 (hu) 2000-06-28
DE69710526D1 (de) 2002-03-28
NO990436D0 (no) 1999-01-29

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UEP Publication of translation of european patent specification