ES2171838T3 - Uso de 3-(4-hexiloxi-1,2,5-tiadiazol-3-il)-1,2,5,6-tetrahidro-1-metilpiridina (xanomelina) para el tratamiento del trastorno bipolar. - Google Patents
Uso de 3-(4-hexiloxi-1,2,5-tiadiazol-3-il)-1,2,5,6-tetrahidro-1-metilpiridina (xanomelina) para el tratamiento del trastorno bipolar.Info
- Publication number
- ES2171838T3 ES2171838T3 ES97305585T ES97305585T ES2171838T3 ES 2171838 T3 ES2171838 T3 ES 2171838T3 ES 97305585 T ES97305585 T ES 97305585T ES 97305585 T ES97305585 T ES 97305585T ES 2171838 T3 ES2171838 T3 ES 2171838T3
- Authority
- ES
- Spain
- Prior art keywords
- bipolar disorder
- methylipiridine
- hexiloxi
- tiadiazol
- tetrahidro
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 208000020925 Bipolar disease Diseases 0.000 title abstract 2
- JOLJIIDDOBNFHW-UHFFFAOYSA-N xanomeline Chemical compound CCCCCCOC1=NSN=C1C1=CCCN(C)C1 JOLJIIDDOBNFHW-UHFFFAOYSA-N 0.000 title 1
- 229950006755 xanomeline Drugs 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
Landscapes
- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Pain & Pain Management (AREA)
- Psychiatry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Electrical Discharge Machining, Electrochemical Machining, And Combined Machining (AREA)
- Medicines Containing Plant Substances (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Plural Heterocyclic Compounds (AREA)
- Electrolytic Production Of Non-Metals, Compounds, Apparatuses Therefor (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Steroid Compounds (AREA)
- Nonmetallic Welding Materials (AREA)
- Processing Of Solid Wastes (AREA)
- Press Drives And Press Lines (AREA)
Abstract
LA PRESENTE INVENCION DESCRIBE UN PROCEDIMIENTO PARA TRATAR EL TRASTORNO BIPOLAR EN SERES HUMANOS UTILIZANDO UN COMPUESTO DE FORMULA I.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US2290096P | 1996-08-01 | 1996-08-01 |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2171838T3 true ES2171838T3 (es) | 2002-09-16 |
Family
ID=21812011
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES97305585T Expired - Lifetime ES2171838T3 (es) | 1996-08-01 | 1997-07-25 | Uso de 3-(4-hexiloxi-1,2,5-tiadiazol-3-il)-1,2,5,6-tetrahidro-1-metilpiridina (xanomelina) para el tratamiento del trastorno bipolar. |
Country Status (19)
Country | Link |
---|---|
EP (1) | EP0821955B1 (es) |
JP (1) | JP2000515547A (es) |
KR (1) | KR20000029647A (es) |
CN (1) | CN1226165A (es) |
AT (1) | ATE213413T1 (es) |
AU (1) | AU716972B2 (es) |
BR (1) | BR9710901A (es) |
CA (1) | CA2261802C (es) |
CZ (1) | CZ27299A3 (es) |
DE (1) | DE69710526T2 (es) |
DK (1) | DK0821955T3 (es) |
EA (1) | EA199900174A1 (es) |
ES (1) | ES2171838T3 (es) |
HU (1) | HUP9904578A2 (es) |
IL (1) | IL128280A0 (es) |
NO (1) | NO990436L (es) |
PL (1) | PL331407A1 (es) |
PT (1) | PT821955E (es) |
WO (1) | WO1998005324A1 (es) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US10265311B2 (en) | 2009-07-22 | 2019-04-23 | PureTech Health LLC | Methods and compositions for treatment of disorders ameliorated by muscarinic receptor activation |
PL3061821T3 (pl) | 2009-07-22 | 2020-01-31 | PureTech Health LLC | Kompozycje do leczenia zaburzeń łagodzonych przez aktywację receptora muskarynowego |
CA2891122C (en) | 2012-11-14 | 2021-07-20 | The Johns Hopkins University | Methods and compositions for treating schizophrenia |
BR112021005802B1 (pt) | 2018-09-28 | 2022-02-15 | Karuna Therapeutics, Inc | Composição farmacêutica oral |
CN111430027B (zh) * | 2020-03-18 | 2023-04-28 | 浙江大学 | 基于肠道微生物的双相情感障碍生物标志物及其筛选应用 |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5043345A (en) * | 1989-02-22 | 1991-08-27 | Novo Nordisk A/S | Piperidine compounds and their preparation and use |
US5376668A (en) * | 1990-08-21 | 1994-12-27 | Novo Nordisk A/S | Heterocyclic compounds |
KR100360575B1 (ko) * | 1993-08-19 | 2003-03-10 | 노보 노르디스크 에이/에스 | 정신분열증및정신분열형질환치료용약제학적조성물 |
US5821371A (en) * | 1994-10-24 | 1998-10-13 | Eli Lilly And Comany | Heterocyclic compounds and their preparation and use |
DE69516076T2 (de) * | 1994-10-31 | 2000-09-14 | Lilly Co Eli | Tetrahydropyridin Oxadiazol- oder -Thiadiazol-Verbindung zur Behandlung von Angstzuständen |
US5488056A (en) * | 1994-10-31 | 1996-01-30 | Eli Lilly And Company | Method for treating anxiety |
-
1997
- 1997-07-25 PT PT97305585T patent/PT821955E/pt unknown
- 1997-07-25 EP EP97305585A patent/EP0821955B1/en not_active Expired - Lifetime
- 1997-07-25 ES ES97305585T patent/ES2171838T3/es not_active Expired - Lifetime
- 1997-07-25 DK DK97305585T patent/DK0821955T3/da active
- 1997-07-25 DE DE69710526T patent/DE69710526T2/de not_active Expired - Lifetime
- 1997-07-25 AT AT97305585T patent/ATE213413T1/de active
- 1997-07-28 IL IL12828097A patent/IL128280A0/xx unknown
- 1997-07-28 CA CA002261802A patent/CA2261802C/en not_active Expired - Lifetime
- 1997-07-28 HU HU9904578A patent/HUP9904578A2/hu unknown
- 1997-07-28 WO PCT/US1997/013185 patent/WO1998005324A1/en not_active Application Discontinuation
- 1997-07-28 CN CN97196820A patent/CN1226165A/zh active Pending
- 1997-07-28 JP JP10508002A patent/JP2000515547A/ja not_active Ceased
- 1997-07-28 KR KR1019997000720A patent/KR20000029647A/ko not_active Application Discontinuation
- 1997-07-28 AU AU40468/97A patent/AU716972B2/en not_active Ceased
- 1997-07-28 CZ CZ99272A patent/CZ27299A3/cs unknown
- 1997-07-28 BR BR9710901A patent/BR9710901A/pt not_active Application Discontinuation
- 1997-07-28 EA EA199900174A patent/EA199900174A1/ru unknown
- 1997-07-28 PL PL97331407A patent/PL331407A1/xx unknown
-
1999
- 1999-01-29 NO NO990436A patent/NO990436L/no unknown
Also Published As
Publication number | Publication date |
---|---|
CA2261802C (en) | 2006-11-07 |
CZ27299A3 (cs) | 1999-08-11 |
BR9710901A (pt) | 1999-08-17 |
ATE213413T1 (de) | 2002-03-15 |
WO1998005324A1 (en) | 1998-02-12 |
CA2261802A1 (en) | 1998-02-12 |
PT821955E (pt) | 2002-07-31 |
EA199900174A1 (ru) | 1999-08-26 |
EP0821955B1 (en) | 2002-02-20 |
AU4046897A (en) | 1998-02-25 |
PL331407A1 (en) | 1999-07-19 |
NO990436D0 (no) | 1999-01-29 |
NO990436L (no) | 1999-01-29 |
KR20000029647A (ko) | 2000-05-25 |
EP0821955A3 (en) | 1998-04-22 |
CN1226165A (zh) | 1999-08-18 |
JP2000515547A (ja) | 2000-11-21 |
EP0821955A2 (en) | 1998-02-04 |
AU716972B2 (en) | 2000-03-09 |
DK0821955T3 (da) | 2002-03-18 |
DE69710526T2 (de) | 2002-10-02 |
IL128280A0 (en) | 1999-11-30 |
DE69710526D1 (de) | 2002-03-28 |
HUP9904578A2 (hu) | 2000-06-28 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FG2A | Definitive protection |
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