ES2176333T3 - Composicion de liberacion controlada acuosa. - Google Patents

Composicion de liberacion controlada acuosa.

Info

Publication number
ES2176333T3
ES2176333T3 ES95924647T ES95924647T ES2176333T3 ES 2176333 T3 ES2176333 T3 ES 2176333T3 ES 95924647 T ES95924647 T ES 95924647T ES 95924647 T ES95924647 T ES 95924647T ES 2176333 T3 ES2176333 T3 ES 2176333T3
Authority
ES
Spain
Prior art keywords
oil
weight percent
total composition
composition
value
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES95924647T
Other languages
English (en)
Inventor
S Esmail Tabibi
Robert W Mendes
Nitin P Pathak
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Medicis Pediatrics Inc
Original Assignee
Medicis Pediatrics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Medicis Pediatrics Inc filed Critical Medicis Pediatrics Inc
Application granted granted Critical
Publication of ES2176333T3 publication Critical patent/ES2176333T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/51—Nanocapsules; Nanoparticles
    • A61K9/5107—Excipients; Inactive ingredients
    • A61K9/5123—Organic compounds, e.g. fats, sugars
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Optics & Photonics (AREA)
  • Nanotechnology (AREA)
  • Biomedical Technology (AREA)
  • Physics & Mathematics (AREA)
  • Medicinal Preparation (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • General Preparation And Processing Of Foods (AREA)
  • Colloid Chemistry (AREA)

Abstract

SE MUESTRA UNA EMULSION ACUOSA DE LIBERACION CONTROLADA, ASI COMO SU METODO DE FABRICACION Y USO COMO VEHICULO PARA SUMINISTRAR MEDICAMENTOS EN FORMA LIQUIDA. LA EMULSION CONTEMPLADA INCLUYE UNA CERA QUE CONTIENE UNA EMULSION DE ACEITE EN AGUA QUE TIENE UN TAMAÑO PARTICULAR MEDIO DE ENTRE 100NM. Y 250NM. APROXIMADAMENTE, UN VALOR PH COMPRENDIDO ENTRE 4.5 Y 8.0 Y UNA VISCOSIDAD A 20-25 C DE 1 A 1000 CPS. APROXIMADAMENTE. LAS FASES DE ACEITE Y AGUA SON EMULSIONADAS MEDIANTE UN AGENTE EMULSIONANTE QUE PERMITE LA LIBERACION DE LA SEPARACION DE FASE A UN VALOR PH DE ENTRE 4.5 Y 8 APROXIMADAMENTE, PERMITIENDO TAMBIEN LA SEPARACION DE FASE A UN VALOR PH INFERIOR 2.0.
ES95924647T 1994-06-21 1995-06-21 Composicion de liberacion controlada acuosa. Expired - Lifetime ES2176333T3 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US26327794A 1994-06-21 1994-06-21
US08/491,626 US5672358A (en) 1994-06-21 1995-06-19 Controlled release aqueous emulsion

Publications (1)

Publication Number Publication Date
ES2176333T3 true ES2176333T3 (es) 2002-12-01

Family

ID=26949751

Family Applications (1)

Application Number Title Priority Date Filing Date
ES95924647T Expired - Lifetime ES2176333T3 (es) 1994-06-21 1995-06-21 Composicion de liberacion controlada acuosa.

Country Status (11)

Country Link
US (1) US5672358A (es)
EP (1) EP0773780B1 (es)
JP (1) JP3583435B2 (es)
AT (1) ATE217186T1 (es)
AU (1) AU706516B2 (es)
CA (1) CA2193497C (es)
DE (1) DE69526655T2 (es)
DK (1) DK0773780T3 (es)
ES (1) ES2176333T3 (es)
WO (1) WO1995035096A1 (es)
ZA (1) ZA955153B (es)

Families Citing this family (36)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2751222B1 (fr) * 1996-07-16 1998-10-09 Capsulis Compositions contenant au moins un acide nucleique et leurs applications dans le domaine biomedical, en particulier en therapie genique
GB9625589D0 (en) * 1996-12-10 1997-01-29 Boots Co Plc Therapeutic agents
US7541020B2 (en) * 1997-05-08 2009-06-02 Corixa Corporation Aminoalkyl glucosaminide phosphate compounds and their use as adjuvants and immunoeffectors
US5891476A (en) * 1997-12-22 1999-04-06 Reo; Joe P. Tastemasked pharmaceutical system
US6682758B1 (en) 1998-12-22 2004-01-27 The United States Of America As Represented By The Department Of Health And Human Services Water-insoluble drug delivery system
IL146567A0 (en) * 1999-06-04 2002-07-25 Skyepharma Inc Oil-core particles containing a hydrophobic core material and hydrophobic drug and method for the preparation thereof
US6703319B1 (en) 1999-06-17 2004-03-09 Micron Technology, Inc. Compositions and methods for removing etch residue
US7153525B1 (en) 2000-03-22 2006-12-26 The University Of Kentucky Research Foundation Microemulsions as precursors to solid nanoparticles
EP1305008A4 (en) * 2001-03-27 2005-02-09 R P Scherer Technologies Inc A Improved forms of pharmaceutical ingredients and method for their preparation
US20040132823A1 (en) * 2001-11-02 2004-07-08 Leo Pavliv Pharmaceutical composition of 2-(4-isobutylphenyl) propionic acid
US7763663B2 (en) * 2001-12-19 2010-07-27 University Of Massachusetts Polysaccharide-containing block copolymer particles and uses thereof
US20030139582A1 (en) * 2002-01-17 2003-07-24 Wang Kai Hua Composition containing biologically active polypeptides suitable for the oral administration
US20030232097A1 (en) * 2002-06-17 2003-12-18 Strides Inc. Oily wax matrix suspension formulation comprising ibuprofen free acid and potassium salt of ibuprofen
US20040213837A1 (en) * 2002-08-05 2004-10-28 Sankaram Mantripragada Oil-core compositions for the sustained release of hydrophobic drugs
AU2003302226A1 (en) * 2002-09-24 2004-06-30 University Of Kentucky Research Foundation Nanoparticle-based vaccine delivery system containing adjuvant
CA2430541A1 (en) * 2003-05-30 2004-11-30 Isomers Laboratories Cosmetic
CN1874755A (zh) * 2003-10-27 2006-12-06 道康宁公司 局部应用的控释组合物和将活性剂输送到基底的方法
US8318210B2 (en) 2005-02-28 2012-11-27 Neos Therapeutics, Lp Compositions and methods of making sustained release liquid formulations
EA012448B1 (ru) * 2005-03-04 2009-10-30 ДСМ АйПи АССЕТС Б.В. Пищевая липидная композиция в форме частиц
CN101384247B (zh) * 2005-07-18 2013-05-22 麻萨诸塞州洛厄尔大学 制备与使用纳米乳剂的组合物和方法
JP2009508855A (ja) * 2005-09-16 2009-03-05 ディーエスエム アイピー アセッツ ビー．ブイ． 医薬品用微粒子状脂質組成物
HUE054852T2 (hu) 2005-12-01 2021-10-28 Univ Massachusetts Lowell Botulinum nanoemulziók
US9486408B2 (en) 2005-12-01 2016-11-08 University Of Massachusetts Lowell Botulinum nanoemulsions
AU2007238114B2 (en) * 2006-04-12 2010-10-14 Biodel, Inc. Rapid acting and long acting insulin combination formulations
US20080118570A1 (en) * 2006-11-20 2008-05-22 Zhi Liu Polymer coated drug-ion exchange resins and methods
CN107080703A (zh) 2006-12-01 2017-08-22 安特里奥公司 肽纳米粒子和其用途
AU2007329579A1 (en) 2006-12-01 2008-06-12 Anterios, Inc. Amphiphilic entity nanoparticles
EP2162117B1 (en) 2007-05-31 2018-02-21 Anterios, Inc. Nucleic acid nanoparticles and uses therefor
GB201006215D0 (en) * 2010-04-14 2010-06-02 Ayanda As Composition
US20120015913A1 (en) * 2010-07-15 2012-01-19 Delansorne Remi Formulations of 14-EPI-Analogues of Vitamin D
BR112013003934A2 (pt) * 2010-08-20 2016-06-07 Reddys Lab Ltd Dr depot de fosfolipídeos
JP6121796B2 (ja) * 2012-05-23 2017-04-26 キユーピー株式会社 脂肪乳剤および医薬品組成物中の非ステロイド性抗炎症薬の含有量を高める方法
JP2019535829A (ja) 2016-11-21 2019-12-12 エイリオン セラピューティクス， インコーポレイテッド 大型薬剤の経皮送達
BR112021011210A2 (pt) 2018-12-10 2021-08-24 EternaTear, Inc. Formulações oftálmicas que proporcionam lubrificação ocular durável
US11471475B1 (en) 2022-03-08 2022-10-18 Ralph P. Stone Ophthalmic suspension vehicles and related methods for pharmaceutical ingredient delivery
US11679078B1 (en) 2022-03-08 2023-06-20 EternaTear, Inc. Ophthalmic formulations and related methods

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IE58110B1 (en) * 1984-10-30 1993-07-14 Elan Corp Plc Controlled release powder and process for its preparation
US5188837A (en) * 1989-11-13 1993-02-23 Nova Pharmaceutical Corporation Lipsopheres for controlled delivery of substances
AU658608B2 (en) * 1991-03-25 1995-04-27 Astellas Pharma Europe B.V. Topical preparation containing a suspension of solid lipid particles
WO1992018147A1 (en) * 1991-04-19 1992-10-29 Affinity Biotech, Inc. Convertible microemulsion formulations
JPH06509577A (ja) * 1991-07-26 1994-10-27 スミスクライン・ビーチャム・コーポレイション Ｗ／ｏミクロエマルジョン
US5576016A (en) * 1993-05-18 1996-11-19 Pharmos Corporation Solid fat nanoemulsions as drug delivery vehicles

Also Published As

Publication number Publication date
US5672358A (en) 1997-09-30
ZA955153B (en) 1996-05-07
EP0773780B1 (en) 2002-05-08
EP0773780A1 (en) 1997-05-21
AU706516B2 (en) 1999-06-17
WO1995035096A1 (en) 1995-12-28
DE69526655D1 (de) 2002-06-13
JP2002510279A (ja) 2002-04-02
CA2193497C (en) 2000-10-17
DK0773780T3 (da) 2002-09-09
DE69526655T2 (de) 2002-12-05
ATE217186T1 (de) 2002-05-15
AU2907095A (en) 1996-01-15
JP3583435B2 (ja) 2004-11-04
EP0773780A4 (en) 1998-09-30
CA2193497A1 (en) 1995-12-28

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