ES2164116T3 - Aparato de analisis con ajuste automatico del dispositivo de transporte de la aguja pipeteadora. - Google Patents

Aparato de analisis con ajuste automatico del dispositivo de transporte de la aguja pipeteadora.

Info

Publication number
ES2164116T3
ES2164116T3 ES95105887T ES95105887T ES2164116T3 ES 2164116 T3 ES2164116 T3 ES 2164116T3 ES 95105887 T ES95105887 T ES 95105887T ES 95105887 T ES95105887 T ES 95105887T ES 2164116 T3 ES2164116 T3 ES 2164116T3
Authority
ES
Spain
Prior art keywords
needle
address
transportation
regard
addresses
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES95105887T
Other languages
English (en)
Inventor
Guido Bonacina
Thomas Caratsch
Rolf Moser
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
F Hoffmann La Roche AG
Original Assignee
F Hoffmann La Roche AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by F Hoffmann La Roche AG filed Critical F Hoffmann La Roche AG
Application granted granted Critical
Publication of ES2164116T3 publication Critical patent/ES2164116T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01B—MEASURING LENGTH, THICKNESS OR SIMILAR LINEAR DIMENSIONS; MEASURING ANGLES; MEASURING AREAS; MEASURING IRREGULARITIES OF SURFACES OR CONTOURS
    • G01B7/00—Measuring arrangements characterised by the use of electric or magnetic techniques
    • G01B7/02—Measuring arrangements characterised by the use of electric or magnetic techniques for measuring length, width or thickness
    • G01B7/023—Measuring arrangements characterised by the use of electric or magnetic techniques for measuring length, width or thickness for measuring distance between sensor and object
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01B—MEASURING LENGTH, THICKNESS OR SIMILAR LINEAR DIMENSIONS; MEASURING ANGLES; MEASURING AREAS; MEASURING IRREGULARITIES OF SURFACES OR CONTOURS
    • G01B7/00—Measuring arrangements characterised by the use of electric or magnetic techniques
    • G01B7/003—Measuring arrangements characterised by the use of electric or magnetic techniques for measuring position, not involving coordinate determination
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/10—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
    • G01N35/1009—Characterised by arrangements for controlling the aspiration or dispense of liquids
    • G01N35/1011—Control of the position or alignment of the transfer device
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/02—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations
    • G01N35/04—Details of the conveyor system
    • G01N2035/0474—Details of actuating means for conveyors or pipettes
    • G01N2035/0491—Position sensing, encoding; closed-loop control
    • G01N2035/0494—Detecting or compensating piositioning errors
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/10—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
    • G01N35/1009—Characterised by arrangements for controlling the aspiration or dispense of liquids
    • G01N35/1011—Control of the position or alignment of the transfer device
    • G01N2035/1013—Confirming presence of tip
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/11—Automated chemical analysis
    • Y10T436/113332—Automated chemical analysis with conveyance of sample along a test line in a container or rack
    • Y10T436/114998—Automated chemical analysis with conveyance of sample along a test line in a container or rack with treatment or replacement of aspirator element [e.g., cleaning, etc.]

Landscapes

  • Physics & Mathematics (AREA)
  • General Physics & Mathematics (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)
  • Sampling And Sample Adjustment (AREA)

Abstract

LA INVENCION SE REFIERE A UN APARATO DE ANALISIS, QUE CONTIENE LOS SIGUIENTES COMPONENTES: A) UNA PLACA (12) BASICA DISPUESTA DE FORMA HORIZONTAL SOBRE EL RECIPIENTE (13 O 23) PRIMARIO Y EL RECIPIENTE (31) SECUNDARIO, B) UNA AGUJA (42) DE PIPETADO QUE SE COMPONE DE UN MATERIAL CONDUCTOR ELECTRICO, UNIDO A TRAVES DE UNA CONDUCCION (99) CON UN DISPOSITIVO (96) DOSIFICADOR PARA LA TRANSMISION DEL VOLUMEN DE LIQUIDO DETERMINADO PREVIAMENTE A PARTIR DE UN RECIPIENTE (13 O 23) PRIMARIO A UN RECIPIENTE (31) SECUNDARIO, C) UN DISPOSITIVO (51-55) DE TRANSPORTE PARA TRANSPORTE CONTROLADO DE LA AGUJA (42) DE PIPETADO EN TRES DIRECCIONES (DIRECCION X, Y, Z) DISPUESTAS VERTICALMENTE UNA CON RESPECTO A OTRA, DONDE DOS DE LAS DIRECCIONES (DIRECCION X O DIRECCION Y) DE TRANSPORTE DISCURREN DE FORMA HORIZONTAL Y LA TERCERA DIRECCION DE TRANSPORTE (DIRECCION Z) DISCURRE DE FORMA VERTICAL, D) UN CUERPO (45) DE REFERENCIA CONDUCTOR ELECTRICO, QUE SE UNE DE FORMA FIJA CON LA PLACA (12) BASICA, QUE DISPONE EN CADA DIRECCION DE TRANSPORTE (DIRECCION X O Y) HORIZONTAL DOS SUPERFICIES (76,77 O 78,79) EXTERIORES, QUE ESTAN DISPUESTAS DE FORMA VERTICAL CON RESPECTO A LA DIRECCION DE TRANSPORTE, E) UN EQUIPO PARA EL CONTROL DEL DISPOSITIVO (96) DOSIFICADOR Y DEL DISPOSITIVO (51-55) DE TRANSPORTE. PARA UN AJUSTE FINO DEL DISPOSITIVO (51-55) DE TRANSPORTE DE LA AGUJA (42) DE PIPETADO EL APARATO DE ANALISIS CONTIENE LOS SIGUIENTES MEDIOS: F) UN CIRCUITO PARA LA MEDICION DE LA CAPACIDAD ELECTRICA ENTRE LA AGUJA (42) DE PIPETADO Y EL CUERPO (45) DE REFERENCIA, Y G) MEDIOS PARA LA DETERMINACION DE LAS COORDINADAS DE UNA POSICION DE REFERENCIA DE LA AGUJA (42) DE PIPETADO EN AL MENOS UNA DE LAS DIRECCIONES (DIRECCION X O Y) DE TRANSPORTE HORIZONTALES. ESTOS MEDIOS SON APROPIADOS DE TAL MODO, QUE EL DISPOSITIVO (51-55) DE TRANSPORTE SE MUEVE CON RESPECTO A LA AGUJA (42) DE PIPETADO, DE MANERA QUE ESTA AGUJA (42) SE MUEVE A SU VEZ EN DIRECCIONES OPUESTAS CON RESPECTO A UNA POSICION EN LA PROXIMIDAD DE CADA UNA DE AMBAS SUPERFICIES (76,77 O 78,79) EXTERIORES DEL CUERPO (45) DE REFERENCIA, ESTANDO DISPUESTAS DE FORMA VERTICAL CON RESPECTO A LA DIRECCION DE TRANSPORTE. LA AGUJA (42) DE PIPETADO SE MUEVE HACIA EL INTERIOR RESPECTIVAMENTE CON RESPECTO A UNA SUPERFICIE DEL CUERPO (45) DE REFERENCIA, HASTA QUE EL VALOR MEDIDO DE LA CAPACIDAD ELECTRICA CON EL CIRCUITO ENTRE LA AGUJA (42) DE PIPETADO Y EL CUERPO (45) DE REFERENCIA ALCANZA UN VALOR PREVIAMENTE DETERMINADO, QUE CORRESPONDE A UNA DISTANCIA DETERMINADA ENTRE LA AGUJA (42) DE PIPETADO Y LA SUPERFICIE DEL CUERPO (45) DE REFERENCIA.
ES95105887T 1994-05-02 1995-04-20 Aparato de analisis con ajuste automatico del dispositivo de transporte de la aguja pipeteadora. Expired - Lifetime ES2164116T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH139394 1994-05-02

Publications (1)

Publication Number Publication Date
ES2164116T3 true ES2164116T3 (es) 2002-02-16

Family

ID=4209384

Family Applications (1)

Application Number Title Priority Date Filing Date
ES95105887T Expired - Lifetime ES2164116T3 (es) 1994-05-02 1995-04-20 Aparato de analisis con ajuste automatico del dispositivo de transporte de la aguja pipeteadora.

Country Status (7)

Country Link
US (1) US5529754A (es)
EP (1) EP0681184B1 (es)
JP (1) JP2799302B2 (es)
AT (1) ATE206212T1 (es)
CA (1) CA2147738A1 (es)
DE (1) DE59509629D1 (es)
ES (1) ES2164116T3 (es)

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CN118419588A (zh) * 2024-07-05 2024-08-02 江苏治宇医疗器材有限责任公司 一种注射器针头的自动输送装置

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US6521187B1 (en) 1996-05-31 2003-02-18 Packard Instrument Company Dispensing liquid drops onto porous brittle substrates
US6537817B1 (en) 1993-05-31 2003-03-25 Packard Instrument Company Piezoelectric-drop-on-demand technology
US6203759B1 (en) 1996-05-31 2001-03-20 Packard Instrument Company Microvolume liquid handling system
US6083762A (en) * 1996-05-31 2000-07-04 Packard Instruments Company Microvolume liquid handling system
DE29720432U1 (de) 1997-11-19 1999-03-25 Heimberg, Wolfgang, Dr., 85560 Ebersberg Roboter
US6270726B1 (en) 1999-09-30 2001-08-07 Dpc Cirrus, Inc. Tube bottom sensing for small fluid samples
JP4717312B2 (ja) 2000-02-29 2011-07-06 ジェン−プローブ・インコーポレイテッド 流体搬送プローブ
US6474181B2 (en) * 2001-01-24 2002-11-05 Gilson, Inc. Probe tip alignment for precision liquid handler
AU2003253279A1 (en) * 2002-03-13 2003-09-29 The Automation Partnership (Cambridge) Limited Low volume droplet dispensing
WO2003100389A1 (en) * 2002-05-28 2003-12-04 Autogenomics, Inc. Multi-reagent pack
EP1710587B1 (en) * 2003-08-20 2016-08-03 Sysmex Corporation Nucleic acid detection method
EP1464965B1 (en) * 2004-01-15 2006-03-08 Agilent Technologies Inc. a Delaware Corporation Positioning system and method for a liquid transfer device
EP1817541B8 (en) * 2004-11-09 2019-09-18 PerkinElmer Health Sciences, Inc. Methods and systems for determining a position of a probe
DE202005014704U1 (de) * 2005-09-16 2007-02-01 C. Gerhardt Fabrik Und Lager Chemischer Apparate Gmbh & Co. Kg Vorrichtung für die Präparation von Ölkompositionen zur Aromatherapie
ES2313200T3 (es) * 2005-09-21 2009-03-01 F. Hoffmann-La Roche Ag Metodo y aparato para el exacto posicionamiento de un dispositivo pipeteador.
JP5102450B2 (ja) * 2006-01-27 2012-12-19 シスメックス株式会社 核酸増幅分析装置
US7457686B2 (en) 2007-03-14 2008-11-25 Ortho—Clinical Diagnostics, Inc. Robotic arm alignment
DE102008010267A1 (de) * 2008-02-19 2009-08-20 Nyársik, Lajos, Dr. Pipettiervorrichtung für manuelle Flüssigkeitshandhabung
JP5377866B2 (ja) * 2008-03-04 2013-12-25 シスメックス株式会社 検体分析装置
US7804599B2 (en) * 2008-07-24 2010-09-28 MGM Instruments, Inc. Fluid volume verification system
DE102008058065A1 (de) * 2008-11-18 2010-05-20 Diasys Diagnostic Systems Gmbh Automatisierte Analysevorrichtung mit einer automatischen Pipettiervorrichtung und mit einer Messvorrichtung zum Bestimmen der Position der Pipettiernadelspitze
DE102010037084A1 (de) 2010-08-20 2012-02-23 LCTech GmbH Probenaufbereitungssystem sowie ein Verfahren zur Bearbeitung einer Probe
JP5653471B2 (ja) * 2013-04-01 2015-01-14 株式会社東芝 自動分析装置
JP2015087329A (ja) * 2013-10-31 2015-05-07 シスメックス株式会社 吸引部の位置調整方法及び検体処理装置
FR3015039B1 (fr) 2013-12-12 2017-02-24 Stago Diagnostica Procede de determination de la position d'au moins un pion de cartographie
EP2955526A1 (de) * 2014-06-10 2015-12-16 Siemens Healthcare Diagnostics Products GmbH Vorrichtung zur Positionsbestimmung einer Lehre und Verfahren zur Positionsbestimmung
ES2897849T3 (es) 2014-07-21 2022-03-02 Siemens Healthcare Diagnostics Products Gmbh Dispositivo para la determinación de posición de un calibrador que se puede desplazar automáticamente
CN204269661U (zh) * 2014-10-28 2015-04-15 利多(香港)有限公司 全自动血球仪的采样装置
JP5899302B2 (ja) * 2014-12-22 2016-04-06 株式会社日立ハイテクノロジーズ 自動分析装置
GB2536227A (en) * 2015-03-09 2016-09-14 Stratec Biomedical Ag Pipettor Autoteaching
EP3088904A1 (de) * 2015-04-27 2016-11-02 Siemens Healthcare Diagnostics Products GmbH Verfahren zur überprüfung der funktionsfähigkeit einer waschstation für pipettiernadeln
WO2017018214A1 (ja) * 2015-07-29 2017-02-02 株式会社日立ハイテクノロジーズ 自動分析装置
CN105277731B (zh) * 2015-09-30 2017-10-24 深圳市新产业生物医学工程股份有限公司 加样系统的定位方法及应用该定位方法的体外诊断仪器
ES2713445T3 (es) * 2016-01-14 2019-05-21 Siemens Healthcare Diagnostics Products Gmbh Procedimiento para comprobar la capacidad de funcionamiento de una bomba dosificadora
US20170220026A1 (en) * 2016-02-01 2017-08-03 Bio-Rad Laboratories, Inc. Direct contact instrument calibration system
CH712735A1 (de) * 2016-07-22 2018-01-31 Tecan Trading Ag Pipettiervorrichtung mit einem Flüssigkeitsvolumensensor und Flüssigkeitsbearbeitungssystem.
WO2018015419A1 (de) * 2016-07-22 2018-01-25 Tecan Trading Ag Pipettenspitze für eine automatisierte pipettiervorrichtung sowie verfahren zu deren herstellung
US12044691B2 (en) * 2018-02-27 2024-07-23 Eppendorf Se Measuring apparatus for a liquid handling apparatus for measuring pipetting container, article for said measuring apparatus and corresponding measuring method
EP4016085A1 (en) 2020-12-21 2022-06-22 Tecan Trading AG Iterative liquid aspiration

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Publication number Priority date Publication date Assignee Title
CN118419588A (zh) * 2024-07-05 2024-08-02 江苏治宇医疗器材有限责任公司 一种注射器针头的自动输送装置

Also Published As

Publication number Publication date
JPH0843404A (ja) 1996-02-16
JP2799302B2 (ja) 1998-09-17
DE59509629D1 (de) 2001-10-31
EP0681184B1 (de) 2001-09-26
CA2147738A1 (en) 1995-11-03
ATE206212T1 (de) 2001-10-15
US5529754A (en) 1996-06-25
EP0681184A1 (de) 1995-11-08

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