ES2163170T3 - Procedimiento de cromatografia en fase inversa. - Google Patents

Procedimiento de cromatografia en fase inversa.

Info

Publication number
ES2163170T3
ES2163170T3 ES97927343T ES97927343T ES2163170T3 ES 2163170 T3 ES2163170 T3 ES 2163170T3 ES 97927343 T ES97927343 T ES 97927343T ES 97927343 T ES97927343 T ES 97927343T ES 2163170 T3 ES2163170 T3 ES 2163170T3
Authority
ES
Spain
Prior art keywords
column
nonionic
contrast media
primary
compound
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES97927343T
Other languages
English (en)
Inventor
Elizabeth Collins
Stephen Muldoon
Brendan O'callaghan
Dominic Carolan
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
MALLINCKRODT MED IMAGING IE
Original Assignee
MALLINCKRODT MED IMAGING IE
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by MALLINCKRODT MED IMAGING IE filed Critical MALLINCKRODT MED IMAGING IE
Application granted granted Critical
Publication of ES2163170T3 publication Critical patent/ES2163170T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08—Selective adsorption, e.g. chromatography
    • B01D15/26—Selective adsorption, e.g. chromatography characterised by the separation mechanism
    • B01D15/32—Bonded phase chromatography
    • B01D15/325—Reversed phase

Landscapes

  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Treatment Of Liquids With Adsorbents In General (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

SE PROPORCIONA UN PROCESO PARA LA DECOLORACION, SEPARACION Y PURIFICACION CROMATOGRAFICAS, EN FASE INVERTIDA, DE COMPUESTOS DE MEDIO DE CONTRASTE NO IONICOS Y SOLUBLES EN AGUA, RESPECTO A SOLUCIONES QUE CONTIENEN IMPUREZAS DE COMPUESTOS NO IONICOS. EL PROCESO COMPRENDE PASAR UNA SOLUCION QUE CONTIENE UN COMPUESTO DE MEDIOS DE CONTRASTE NO IONICOS Y SOLUBLES EN AGUA Y COMPUESTOS NO IONICOS COMO IMPUREZAS A TRAVES DE UN MATERIAL EMPAQUETADO CROMATOGRAFICO EN UNA COLUMNA CROMATOGRAFICA PRIMARIA. LA COLUMNA PRIMARIA SE SOMETE A ERUPCION, PARA PRODUCIR UN ELUADO PRIMARIO QUE CONTIENE COMPUESTO DE MEDIOS DE CONTRASTE NO IONICOS, SOLUBLES EN AGUA Y PRACTICAMENTE PUROS. A CONTINUACION, SE HACE PASAR UN DISOLVENTE, ESPECIALMENTE METANOL, A TRAVES DE LA COLUMNA PRIMARIA, PARA LAVAR UNA COLUMNA INICIAL SOSTENIDA POR LA COLUMNA. EL COMPUESTO DE MEDIOS DE CONTRASTE NO IONICOS SE RECUPERA A CONTINUACION DE LA RETENCION DE LA COLUMNA INICIAL.
ES97927343T 1996-06-05 1997-06-04 Procedimiento de cromatografia en fase inversa. Expired - Lifetime ES2163170T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IE960412 1996-06-05

Publications (1)

Publication Number Publication Date
ES2163170T3 true ES2163170T3 (es) 2002-01-16

Family

ID=11041183

Family Applications (1)

Application Number Title Priority Date Filing Date
ES97927343T Expired - Lifetime ES2163170T3 (es) 1996-06-05 1997-06-04 Procedimiento de cromatografia en fase inversa.

Country Status (8)

Country Link
EP (1) EP0907395B1 (es)
AT (1) ATE208223T1 (es)
AU (1) AU3187197A (es)
DE (1) DE69708090T2 (es)
ES (1) ES2163170T3 (es)
GB (1) GB2328385B (es)
NO (1) NO323772B1 (es)
WO (1) WO1997046299A1 (es)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101961564B (zh) * 2010-08-13 2012-07-04 浙江大学宁波理工学院 五区模拟移动床色谱分离系统
FR3084668A1 (fr) 2018-08-02 2020-02-07 Guerbet Procede de preparation monotope de composes organo-iodes intermediaires a la synthese du ioversol
CN112724035A (zh) * 2021-03-01 2021-04-30 江苏汉邦科技有限公司 一种纯化制备碘佛醇水解物的方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5204005A (en) * 1990-02-26 1993-04-20 Mallinckrodt, Inc. Reversed phase chromatographic process
GB2321860A (en) * 1995-12-01 1998-08-12 Mallinckrodt Med Imaging Ie Reversed phase chromatographic process
AU7707096A (en) * 1995-12-01 1997-06-27 Mallinckrodt Medical Imaging-Ireland Reversed phase chromatographic process

Also Published As

Publication number Publication date
IE970412A1 (en) 1997-12-17
NO985542L (no) 1999-01-18
ATE208223T1 (de) 2001-11-15
GB9824512D0 (en) 1999-01-06
WO1997046299A1 (en) 1997-12-11
GB2328385B (en) 2000-10-25
DE69708090D1 (de) 2001-12-13
NO985542D0 (no) 1998-11-27
NO323772B1 (no) 2007-07-02
AU3187197A (en) 1998-01-05
EP0907395B1 (en) 2001-11-07
GB2328385A (en) 1999-02-24
EP0907395A1 (en) 1999-04-14
DE69708090T2 (de) 2002-07-18

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