ES2162126T3 - Nuevos taxoides, su preparacion y las composiciones farmaceuticas que les contienen. - Google Patents
Nuevos taxoides, su preparacion y las composiciones farmaceuticas que les contienen.Info
- Publication number
- ES2162126T3 ES2162126T3 ES96942432T ES96942432T ES2162126T3 ES 2162126 T3 ES2162126 T3 ES 2162126T3 ES 96942432 T ES96942432 T ES 96942432T ES 96942432 T ES96942432 T ES 96942432T ES 2162126 T3 ES2162126 T3 ES 2162126T3
- Authority
- ES
- Spain
- Prior art keywords
- radical
- general formula
- preparation
- pharmaceutical compositions
- contain
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 239000008194 pharmaceutical composition Substances 0.000 title abstract 2
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
- YZCKVEUIGOORGS-UHFFFAOYSA-N Hydrogen atom Chemical compound [H] YZCKVEUIGOORGS-UHFFFAOYSA-N 0.000 abstract 1
- 125000004423 acyloxy group Chemical group 0.000 abstract 1
- 230000005916 anti-leucemic effect Effects 0.000 abstract 1
- 230000000259 anti-tumor effect Effects 0.000 abstract 1
- 125000005333 aroyloxy group Chemical group 0.000 abstract 1
- -1 carbamoyloxy Chemical group 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Chemical compound O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D305/00—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms
- C07D305/14—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms condensed with carbocyclic rings or ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Epoxy Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
LA INVENCION SE REFIERE A NUEVOS TAXOIDES DE FORMULA GENERAL (I), A SU PREPARACION Y A LAS COMPOSICIONES FARMACEUTICAS QUE LOS CONTIENEN. EN LA FORMULA GENERAL (I), Z REPRESENTA UN ATOMO DE HIDROGENO O UN RADICAL DE FORMULA GENERAL (II), EN LA CUAL R 1 REPRESENTA UN RADICAL BEZOILO OPCIONALMENTE SUSTITUIDO, FUROILO O TENOILO O UN RADICAL R 2 - O - CO - EN EL CUAL R 2 REPRESENTA UN RADICAL ALCOILO, ALCENILO, ALCINILO, CICLOALCOILO, CICLOALCENILO, FENILO, NAFTILO O HETEROCICLICO AROMATICO; R 4 REPRESENTA UN ATOMO DE HIDROGENO O UN RADICAL HIDROXI O UN RADICAL ALCOXI, ALCENILOXI, ALCINILOXI OPCIONALMENTE SUSTITUIDO, ALCANOILOXI, ALCENOILOXI, ALCINOILOXI, CICLOALCANOILOXI, AROILOXI, ALCOXIACETILO, ALCOILACETILO, ALCOILOXICARBONILOXI O UN RADICAL CICLOALCOILOXI, CICLOALCENILOXI, CARBAMOILOXI, ALCOILCARBAMOILOXI O DIALCOILCARBAMOILOXI. LOS NUEVOS PRODUCTOS DE FORMULA GENERAL (I) EN LA CUAL Z REPRESENTA UN RADICAL DE FORMULA GENERAL (II) PRESENTAN PROPIEDADES ANTITUMORALES Y ANTILEUCEMICAS NOTABLES.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR9515380A FR2742753B1 (fr) | 1995-12-22 | 1995-12-22 | Nouveaux taxoides, leur preparation et les compositions pharmaceutiques qui les contiennent |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2162126T3 true ES2162126T3 (es) | 2001-12-16 |
Family
ID=9485872
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES96942432T Expired - Lifetime ES2162126T3 (es) | 1995-12-22 | 1996-12-19 | Nuevos taxoides, su preparacion y las composiciones farmaceuticas que les contienen. |
Country Status (18)
| Country | Link |
|---|---|
| US (1) | US5968931A (es) |
| EP (1) | EP0874838B1 (es) |
| JP (1) | JP2000502670A (es) |
| AR (1) | AR004406A1 (es) |
| AT (1) | ATE204265T1 (es) |
| AU (1) | AU1180897A (es) |
| CO (1) | CO4750812A1 (es) |
| DE (1) | DE69614568T2 (es) |
| DK (1) | DK0874838T3 (es) |
| ES (1) | ES2162126T3 (es) |
| FR (1) | FR2742753B1 (es) |
| GR (1) | GR3036411T3 (es) |
| MA (1) | MA26411A1 (es) |
| PT (1) | PT874838E (es) |
| TN (1) | TNSN96168A1 (es) |
| TW (1) | TW363968B (es) |
| WO (1) | WO1997023472A1 (es) |
| ZA (1) | ZA9610740B (es) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5973160A (en) | 1992-12-23 | 1999-10-26 | Poss; Michael A. | Methods for the preparation of novel sidechain-bearing taxanes |
| JPH1192468A (ja) * | 1997-09-17 | 1999-04-06 | Yakult Honsha Co Ltd | 新規なタキサン誘導体 |
| EP1318794A2 (en) | 2000-09-22 | 2003-06-18 | Bristol-Myers Squibb Company | Method for reducing toxicity of combined chemotherapies |
| EP1663153A4 (en) * | 2003-05-20 | 2011-01-05 | Aronex Pharmaceuticals Inc | COMBINATION SCHEMOTHERAPY WITH A LIPOSOMAL PLATINUM COMPLEX |
| AU2007226937A1 (en) * | 2006-03-21 | 2007-09-27 | Dr. Reddy's Laboratories Ltd. | Docetaxel polymorphs and processes |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9224922D0 (en) * | 1992-11-27 | 1993-01-13 | Smithkline Beecham Plc | Process |
| US5380751A (en) * | 1992-12-04 | 1995-01-10 | Bristol-Myers Squibb Company | 6,7-modified paclitaxels |
| CA2109861C (en) * | 1992-12-04 | 1999-03-16 | Shu-Hui Chen | 6,7-modified paclitaxels |
| FR2698871B1 (fr) * | 1992-12-09 | 1995-02-24 | Rhone Poulenc Rorer Sa | Nouveau taxoïdes, leur préparation et les compositions pharmaceutiques qui les contiennent. |
-
1995
- 1995-12-22 FR FR9515380A patent/FR2742753B1/fr not_active Expired - Fee Related
-
1996
- 1996-12-18 MA MA24430A patent/MA26411A1/fr unknown
- 1996-12-19 WO PCT/FR1996/002030 patent/WO1997023472A1/fr active IP Right Grant
- 1996-12-19 DK DK96942432T patent/DK0874838T3/da active
- 1996-12-19 AU AU11808/97A patent/AU1180897A/en not_active Abandoned
- 1996-12-19 ZA ZA9610740A patent/ZA9610740B/xx unknown
- 1996-12-19 AT AT96942432T patent/ATE204265T1/de not_active IP Right Cessation
- 1996-12-19 EP EP96942432A patent/EP0874838B1/fr not_active Expired - Lifetime
- 1996-12-19 DE DE69614568T patent/DE69614568T2/de not_active Expired - Fee Related
- 1996-12-19 PT PT96942432T patent/PT874838E/pt unknown
- 1996-12-19 ES ES96942432T patent/ES2162126T3/es not_active Expired - Lifetime
- 1996-12-19 US US09/091,188 patent/US5968931A/en not_active Expired - Fee Related
- 1996-12-19 JP JP9523360A patent/JP2000502670A/ja active Pending
- 1996-12-20 TW TW085115803A patent/TW363968B/zh active
- 1996-12-20 CO CO96067022A patent/CO4750812A1/es unknown
- 1996-12-20 TN TNTNSN96168A patent/TNSN96168A1/fr unknown
- 1996-12-20 AR ARP960105852A patent/AR004406A1/es unknown
-
2001
- 2001-08-20 GR GR20010400635T patent/GR3036411T3/el not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| PT874838E (pt) | 2001-12-28 |
| GR3036411T3 (en) | 2001-11-30 |
| FR2742753A1 (fr) | 1997-06-27 |
| TNSN96168A1 (fr) | 2005-03-15 |
| ATE204265T1 (de) | 2001-09-15 |
| DE69614568D1 (de) | 2001-09-20 |
| TW363968B (en) | 1999-07-11 |
| FR2742753B1 (fr) | 1998-01-30 |
| AR004406A1 (es) | 1998-11-04 |
| EP0874838A1 (fr) | 1998-11-04 |
| DE69614568T2 (de) | 2002-06-27 |
| EP0874838B1 (fr) | 2001-08-16 |
| WO1997023472A1 (fr) | 1997-07-03 |
| CO4750812A1 (es) | 1999-03-31 |
| AU1180897A (en) | 1997-07-17 |
| JP2000502670A (ja) | 2000-03-07 |
| US5968931A (en) | 1999-10-19 |
| DK0874838T3 (da) | 2001-12-17 |
| ZA9610740B (en) | 1997-06-27 |
| MA26411A1 (fr) | 2004-12-20 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG2A | Definitive protection |
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