ES2161758T3 - Producto de copulacion de la histamina y de un acido aminado. - Google Patents
Producto de copulacion de la histamina y de un acido aminado.Info
- Publication number
- ES2161758T3 ES2161758T3 ES94907600T ES94907600T ES2161758T3 ES 2161758 T3 ES2161758 T3 ES 2161758T3 ES 94907600 T ES94907600 T ES 94907600T ES 94907600 T ES94907600 T ES 94907600T ES 2161758 T3 ES2161758 T3 ES 2161758T3
- Authority
- ES
- Spain
- Prior art keywords
- histamine
- radical
- represent
- replaced
- amino acid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/64—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms, e.g. histidine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
- A61K8/65—Collagen; Gelatin; Keratin; Derivatives or degradation products thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/12—Ophthalmic agents for cataracts
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/14—Decongestants or antiallergics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q17/00—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
- A61Q17/04—Topical preparations for affording protection against sunlight or other radiation; Topical sun tanning preparations
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
- A61K2800/52—Stabilizers
- A61K2800/522—Antioxidants; Radical scavengers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q17/00—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/002—Aftershave preparations
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/08—Anti-ageing preparations
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Medicinal Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Dermatology (AREA)
- Epidemiology (AREA)
- Birds (AREA)
- Ophthalmology & Optometry (AREA)
- Immunology (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Vascular Medicine (AREA)
- Urology & Nephrology (AREA)
- Pulmonology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
Abstract
LA INVENCION SE REFIERE A UN PRODUCTO SEUDODIPEPTIDO OBTENIDO POR ACOPLAMIENTO ENTRE LA HISTAMINA O LA HISTAMINA METILSUSTITUIDA Y UN AMINOACIDO QUE TIENE POR FORMULA (I), EN LA QUE A REPRESENTA UN RADICAL ELEGIDO EN EL GRUPO QUE CONSISTE EN RADICALES AMINOS, AMIDOS, LACTAMOS URETANOS; R{1}, R''{1}, R2, R''{2}....R{N}, R''{N} REPRESENTAN CADA UNO UN ATOMO DE HIDROGENO, UN RADICAL HIDROCARBONADO O UN GRUPO FUNCIONAL; Y Y Z REPRESENTAN CADA UNO UN ATOMO DE HIDROGENO O DE FLUOR, O UN RADICAL HIDROCARBONADO QUE PUEDE ESTAR SUSTITUIDO POR UNO O VARIOS GRUPOS FUNCIONALES; Y N ES UN NUMERO ENTERO SUPERIOR O IGUAL A 1: SIENDO LA CONEXION COVALENTE CON LA HISTAMINA O LA HISTAMINA METIL-SUSTITUIDA UNA CONEXION PEPTIDICA ENTRE EL RADICAL CARBOXILICO DEL AMINOACIDO Y EL RADICAL AMINO DE LA HISTAMINA. LOS PRODUCTOS SEUDODIPEPTIDOS DE LA INVENCION PUEDEN SER UTILIZADOS EN VARIAS APLICACIONES TERAPEUTICAS, COSMETOLOGICAS Y AGROALIMENTARIAS Y EN PARTICULAR PARA EL TRATAMIENTO DE LA CATARATA.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR9302295A FR2701947B1 (fr) | 1993-02-22 | 1993-02-22 | Produit de couplage de l'histamine et d'un acide aminé, procédé de préparation, et applications thérapeutiques et cosmétologiques. |
FR9310486A FR2701948B1 (fr) | 1993-02-22 | 1993-08-30 | Produit de couplage de l'histamine ou l'histamine méthyl-substituée et d'un acide aminé, procédé de préparation et applications thérapeutiques, cosmétologiques et agroalimentaires. |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2161758T3 true ES2161758T3 (es) | 2001-12-16 |
Family
ID=26230131
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES94907600T Expired - Lifetime ES2161758T3 (es) | 1993-02-22 | 1994-02-21 | Producto de copulacion de la histamina y de un acido aminado. |
Country Status (11)
Country | Link |
---|---|
US (1) | US5792784A (es) |
EP (1) | EP0684944B1 (es) |
JP (1) | JP3373852B2 (es) |
BR (1) | BR9406126A (es) |
DE (1) | DE69427814T2 (es) |
ES (1) | ES2161758T3 (es) |
FR (1) | FR2701948B1 (es) |
GR (1) | GR3036979T3 (es) |
MX (1) | MX9401347A (es) |
RU (1) | RU2166510C2 (es) |
WO (1) | WO1994019325A1 (es) |
Families Citing this family (22)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2711990B1 (fr) * | 1993-11-05 | 1995-12-08 | Exsymol Sa | Produit pseudodipeptide possédant un groupement imidazole, et applications thérapeutiques, cosmétologiques et agroalimentaires. |
CA2187482A1 (en) * | 1995-10-13 | 1997-04-14 | Eri Inoue | Pharmaceutical composition |
JP3877807B2 (ja) * | 1996-07-03 | 2007-02-07 | ゼリア新薬工業株式会社 | 口内炎治療・予防剤 |
RU2141483C1 (ru) * | 1997-07-04 | 1999-11-20 | Небольсин Владимир Евгеньевич | Производные пептидов или их фармацевтически приемлемые соли, способ их получения, применение и фармацевтическая композиция |
AU742237B2 (en) * | 1998-07-14 | 2001-12-20 | Alcon Manufacturing Limited | Use of 11-(3-dimenthylaminopropylidene)-6,11-dihydrodibenz (B,E)oxepin-2-acetic acid for the manufacture of medicament for treating non-allergic opthalmic inflammatory disorders and for the prevention of ocular neovascularization |
FR2794974B1 (fr) * | 1999-06-16 | 2001-08-17 | Exsymol Sa | Composition cosmetique pour l'amincissement a base de l-arginine, d'un analogue de l-arginine ou d'un de leurs derives, applicable par voie topique |
AUPQ515000A0 (en) * | 2000-01-19 | 2000-02-10 | Grigg, Geoffrey Walter | Treatment of uv induced immunosuppression |
DE50214837D1 (de) * | 2001-09-06 | 2011-02-10 | Lonza Ag | Verfahren zur herstellung von beta-alaninamiden |
US20030149090A1 (en) * | 2001-11-06 | 2003-08-07 | Gehlsen Kurt R. | Compositions for the treatment of infectious diseases |
JP2003171276A (ja) * | 2001-11-30 | 2003-06-17 | Menicon Co Ltd | 眼精疲労改善眼科用組成物 |
WO2004028536A1 (en) * | 2002-09-30 | 2004-04-08 | Babizhayev Mark A | Method for topical treatment of eye disease and composition and device for said treatment |
MC200060A1 (fr) * | 2002-10-04 | 2003-05-28 | M Exsymol Sa | Produit de couplage entre la tryptamine et un alpha-aminoacide son procédé de préparation et son application dans le domaine de la neuro-cosmétique |
JPWO2004064866A1 (ja) | 2003-01-20 | 2006-05-18 | イノヴェイティブ ヴィジョン プロダクツ インコーポレーテッド | カルノシナーゼ阻害剤とl−カルノシン類との併用および組成物 |
AU2003226582A1 (en) * | 2003-04-18 | 2004-11-04 | Institut National De La Sante Et De La Recherche Medicale (Inserm) | Use of beta-aminoisobutyric acid for the treatment of diseases linked to the accumulation of triglycerides and cholesterol |
US20060275278A1 (en) * | 2005-06-02 | 2006-12-07 | Choy Camus K M | Method and ophthalmic formulation for eye protection or treatment |
FR2980377B1 (fr) * | 2011-09-22 | 2013-10-04 | Total Raffinage Marketing | Procede de regeneration d'un catalyseur enzymatique |
US8883857B2 (en) | 2012-12-07 | 2014-11-11 | Baylor College Of Medicine | Small molecule xanthine oxidase inhibitors and methods of use |
JP6326601B2 (ja) | 2013-03-13 | 2018-05-23 | アンティース ソシエテ アノニム | 皮膚更新のためのペプチド及び前記ペプチドを使用する方法 |
FR3030523B1 (fr) * | 2014-12-18 | 2017-01-20 | Oreal | Nouveaux composes de la famille des n-acylamino-amides,compositions les comprenant, et utilisations |
CN110981810A (zh) * | 2019-12-19 | 2020-04-10 | 东莞市维琪科技有限公司 | 一种脱羧肌肽的合成方法 |
CN114213336A (zh) * | 2021-12-24 | 2022-03-22 | 深圳瑞德林生物技术有限公司 | β-丙氨酰-L-组氨的制备方法 |
CN114250204B (zh) * | 2021-12-29 | 2024-02-09 | 深圳瑞德林生物技术有限公司 | 一种羧酸还原酶突变体及酶法合成脱羧肌肽的方法 |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4381239A (en) * | 1981-02-10 | 1983-04-26 | Tanabe Seiyaku Co., Ltd. | Method for reducing the pyrogen content of or removing pyrogens from substances contaminated therewith |
IT1206078B (it) * | 1987-06-03 | 1989-04-14 | Polifarma Spa | Procedimento per la produzione di acido 3-indolpiruvico e suoi derivati loro uso farmaceutico |
WO1989003842A1 (en) * | 1987-10-21 | 1989-05-05 | The Upjohn Company | Renin inhibitors containing a (1-amino-2-hydroxy-2-heterocyclic) ethyl moiety |
EP0571390B1 (en) | 1990-11-23 | 2000-03-08 | Peptech Limited | The delay, prevention and/or reversal of cell senescence |
DE69231576T2 (de) * | 1991-09-09 | 2001-06-13 | Peptech Ltd | Verwendung von Peptiden ZUR BEHANDLUNG VON KOMPLIKATIONEN UND PATHOLOGY BEI DIABETES |
-
1993
- 1993-08-30 FR FR9310486A patent/FR2701948B1/fr not_active Expired - Lifetime
-
1994
- 1994-02-21 WO PCT/FR1994/000189 patent/WO1994019325A1/fr active IP Right Grant
- 1994-02-21 DE DE69427814T patent/DE69427814T2/de not_active Expired - Lifetime
- 1994-02-21 RU RU95118405/04A patent/RU2166510C2/ru not_active IP Right Cessation
- 1994-02-21 EP EP94907600A patent/EP0684944B1/fr not_active Expired - Lifetime
- 1994-02-21 JP JP51871294A patent/JP3373852B2/ja not_active Expired - Fee Related
- 1994-02-21 ES ES94907600T patent/ES2161758T3/es not_active Expired - Lifetime
- 1994-02-21 US US08/507,266 patent/US5792784A/en not_active Expired - Lifetime
- 1994-02-21 BR BR9406126A patent/BR9406126A/pt not_active Application Discontinuation
- 1994-02-22 MX MX9401347A patent/MX9401347A/es unknown
-
2001
- 2001-10-22 GR GR20010401849T patent/GR3036979T3/el unknown
Also Published As
Publication number | Publication date |
---|---|
EP0684944B1 (fr) | 2001-07-25 |
WO1994019325A1 (fr) | 1994-09-01 |
US5792784A (en) | 1998-08-11 |
JP3373852B2 (ja) | 2003-02-04 |
FR2701948A1 (fr) | 1994-09-02 |
DE69427814T2 (de) | 2002-04-04 |
MX9401347A (es) | 1994-08-31 |
FR2701948B1 (fr) | 1996-07-26 |
JPH08506825A (ja) | 1996-07-23 |
RU2166510C2 (ru) | 2001-05-10 |
DE69427814D1 (de) | 2001-08-30 |
GR3036979T3 (en) | 2002-01-31 |
BR9406126A (pt) | 1996-02-13 |
EP0684944A1 (fr) | 1995-12-06 |
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Legal Events
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