DE69427814D1 - Kupplungsprodukt zwischen einer aminosaeure und histamin - Google Patents

Kupplungsprodukt zwischen einer aminosaeure und histamin

Info

Publication number
DE69427814D1
DE69427814D1 DE69427814T DE69427814T DE69427814D1 DE 69427814 D1 DE69427814 D1 DE 69427814D1 DE 69427814 T DE69427814 T DE 69427814T DE 69427814 T DE69427814 T DE 69427814T DE 69427814 D1 DE69427814 D1 DE 69427814D1
Authority
DE
Germany
Prior art keywords
histamine
amino acid
clutch product
clutch
product
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69427814T
Other languages
English (en)
Other versions
DE69427814T2 (de
Inventor
Marc Babizhayev
Marie-Christine Seguin
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Exsymol SAM
Original Assignee
Exsymol SAM
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from FR9302295A external-priority patent/FR2701947B1/fr
Application filed by Exsymol SAM filed Critical Exsymol SAM
Publication of DE69427814D1 publication Critical patent/DE69427814D1/de
Application granted granted Critical
Publication of DE69427814T2 publication Critical patent/DE69427814T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/64—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms, e.g. histidine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
    • A61K8/65—Collagen; Gelatin; Keratin; Derivatives or degradation products thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/12—Ophthalmic agents for cataracts
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/14—Decongestants or antiallergics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q17/00—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
    • A61Q17/04—Topical preparations for affording protection against sunlight or other radiation; Topical sun tanning preparations
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/52—Stabilizers
    • A61K2800/522—Antioxidants; Radical scavengers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q17/00—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A61Q19/002—Aftershave preparations
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A61Q19/08—Anti-ageing preparations
DE69427814T 1993-02-22 1994-02-21 Kupplungsprodukt zwischen einer aminosaeure und histamin Expired - Lifetime DE69427814T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
FR9302295A FR2701947B1 (fr) 1993-02-22 1993-02-22 Produit de couplage de l'histamine et d'un acide aminé, procédé de préparation, et applications thérapeutiques et cosmétologiques.
FR9310486A FR2701948B1 (fr) 1993-02-22 1993-08-30 Produit de couplage de l'histamine ou l'histamine méthyl-substituée et d'un acide aminé, procédé de préparation et applications thérapeutiques, cosmétologiques et agroalimentaires.
PCT/FR1994/000189 WO1994019325A1 (fr) 1993-02-22 1994-02-21 Produit de couplage de l'histamine et d'un acide amine

Publications (2)

Publication Number Publication Date
DE69427814D1 true DE69427814D1 (de) 2001-08-30
DE69427814T2 DE69427814T2 (de) 2002-04-04

Family

ID=26230131

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69427814T Expired - Lifetime DE69427814T2 (de) 1993-02-22 1994-02-21 Kupplungsprodukt zwischen einer aminosaeure und histamin

Country Status (11)

Country Link
US (1) US5792784A (de)
EP (1) EP0684944B1 (de)
JP (1) JP3373852B2 (de)
BR (1) BR9406126A (de)
DE (1) DE69427814T2 (de)
ES (1) ES2161758T3 (de)
FR (1) FR2701948B1 (de)
GR (1) GR3036979T3 (de)
MX (1) MX9401347A (de)
RU (1) RU2166510C2 (de)
WO (1) WO1994019325A1 (de)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2711990B1 (fr) * 1993-11-05 1995-12-08 Exsymol Sa Produit pseudodipeptide possédant un groupement imidazole, et applications thérapeutiques, cosmétologiques et agroalimentaires.
CA2187482A1 (en) * 1995-10-13 1997-04-14 Eri Inoue Pharmaceutical composition
JP3877807B2 (ja) * 1996-07-03 2007-02-07 ゼリア新薬工業株式会社 口内炎治療・予防剤
RU2141483C1 (ru) * 1997-07-04 1999-11-20 Небольсин Владимир Евгеньевич Производные пептидов или их фармацевтически приемлемые соли, способ их получения, применение и фармацевтическая композиция
ATE203668T1 (de) * 1998-07-14 2001-08-15 Alcon Lab Inc Verwendung von 11-(3-dimethylaminopropyliden)-6, 11-dihydrodibenz(b,e)oxepin-2-essigsäure und deren pharmazeutisch annehmbaren salzen zur herstellung eines medikaments zur behandlung nicht-allergisch-bedingten augenentzündungen und zur prevention der okularen neovaskularisation
FR2794974B1 (fr) * 1999-06-16 2001-08-17 Exsymol Sa Composition cosmetique pour l'amincissement a base de l-arginine, d'un analogue de l-arginine ou d'un de leurs derives, applicable par voie topique
AUPQ515000A0 (en) * 2000-01-19 2000-02-10 Grigg, Geoffrey Walter Treatment of uv induced immunosuppression
DE50214837D1 (de) 2001-09-06 2011-02-10 Lonza Ag Verfahren zur herstellung von beta-alaninamiden
KR20050043763A (ko) * 2001-11-06 2005-05-11 맥심 파마수티컬즈 인크. 감염 질환의 치료용 조성물
JP2003171276A (ja) * 2001-11-30 2003-06-17 Menicon Co Ltd 眼精疲労改善眼科用組成物
US7795203B2 (en) * 2002-09-30 2010-09-14 Babizhayev Mark A Method for topical treatment of eye disease and composition and device for said treatment
MC200060A1 (fr) 2002-10-04 2003-05-28 M Exsymol Sa Produit de couplage entre la tryptamine et un alpha-aminoacide son procédé de préparation et son application dans le domaine de la neuro-cosmétique
JPWO2004064866A1 (ja) 2003-01-20 2006-05-18 イノヴェイティブ ヴィジョン プロダクツ インコーポレーテッド カルノシナーゼ阻害剤とｌ−カルノシン類との併用および組成物
AU2003226582A1 (en) * 2003-04-18 2004-11-04 Institut National De La Sante Et De La Recherche Medicale (Inserm) Use of beta-aminoisobutyric acid for the treatment of diseases linked to the accumulation of triglycerides and cholesterol
US20060275278A1 (en) * 2005-06-02 2006-12-07 Choy Camus K M Method and ophthalmic formulation for eye protection or treatment
FR2980377B1 (fr) * 2011-09-22 2013-10-04 Total Raffinage Marketing Procede de regeneration d'un catalyseur enzymatique
US8883857B2 (en) 2012-12-07 2014-11-11 Baylor College Of Medicine Small molecule xanthine oxidase inhibitors and methods of use
KR102276326B1 (ko) 2013-03-13 2021-07-13 앙테이스 에스.아. 피부 회춘을 위한 펩타이드 및 이것을 사용하는 방법
FR3030523B1 (fr) * 2014-12-18 2017-01-20 Oreal Nouveaux composes de la famille des n-acylamino-amides,compositions les comprenant, et utilisations
CN110981810A (zh) * 2019-12-19 2020-04-10 东莞市维琪科技有限公司 一种脱羧肌肽的合成方法
CN114213336A (zh) * 2021-12-24 2022-03-22 深圳瑞德林生物技术有限公司 β-丙氨酰-L-组氨的制备方法
CN114250204B (zh) * 2021-12-29 2024-02-09 深圳瑞德林生物技术有限公司 一种羧酸还原酶突变体及酶法合成脱羧肌肽的方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4381239A (en) * 1981-02-10 1983-04-26 Tanabe Seiyaku Co., Ltd. Method for reducing the pyrogen content of or removing pyrogens from substances contaminated therewith
IT1206078B (it) * 1987-06-03 1989-04-14 Polifarma Spa Procedimento per la produzione di acido 3-indolpiruvico e suoi derivati loro uso farmaceutico
WO1989003842A1 (en) * 1987-10-21 1989-05-05 The Upjohn Company Renin inhibitors containing a (1-amino-2-hydroxy-2-heterocyclic) ethyl moiety
WO1992009298A1 (en) 1990-11-23 1992-06-11 Peptide Technology Ltd. The delay, prevention and/or reversal of cell senescence
JPH07500580A (ja) * 1991-09-09 1995-01-19 ペプテック　リミテッド 糖尿病の合併症及び病因の処理方法

Also Published As

Publication number Publication date
JPH08506825A (ja) 1996-07-23
JP3373852B2 (ja) 2003-02-04
WO1994019325A1 (fr) 1994-09-01
BR9406126A (pt) 1996-02-13
FR2701948A1 (fr) 1994-09-02
RU2166510C2 (ru) 2001-05-10
EP0684944A1 (de) 1995-12-06
EP0684944B1 (de) 2001-07-25
MX9401347A (es) 1994-08-31
ES2161758T3 (es) 2001-12-16
US5792784A (en) 1998-08-11
DE69427814T2 (de) 2002-04-04
FR2701948B1 (fr) 1996-07-26
GR3036979T3 (en) 2002-01-31

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8328 Change in the person/name/address of the agent

Representative=s name: GROSSE, BOCKHORNI, SCHUMACHER, 81476 MUENCHEN

8328 Change in the person/name/address of the agent

Representative=s name: BOCKHORNI & KOLLEGEN, 80687 MUENCHEN