MX9401347A - Producto de acoplamiento de la histamina o de la histamina metil substituida y de un acido aminado, procedimiento de preparacion y aplicaciones terapeuticas, cosmetogoligas y agroalimentarias. - Google Patents

Producto de acoplamiento de la histamina o de la histamina metil substituida y de un acido aminado, procedimiento de preparacion y aplicaciones terapeuticas, cosmetogoligas y agroalimentarias.

Info

Publication number
MX9401347A
MX9401347A MX9401347A MX9401347A MX9401347A MX 9401347 A MX9401347 A MX 9401347A MX 9401347 A MX9401347 A MX 9401347A MX 9401347 A MX9401347 A MX 9401347A MX 9401347 A MX9401347 A MX 9401347A
Authority
MX
Mexico
Prior art keywords
histamine
therapeutic
food applications
radical
cosmetogological
Prior art date
Application number
MX9401347A
Other languages
English (en)
Inventor
Marc Babizhayev
Original Assignee
Exsymol S A
Marc Babizhayev
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from FR9302295A external-priority patent/FR2701947B1/fr
Application filed by Exsymol S A, Marc Babizhayev filed Critical Exsymol S A
Publication of MX9401347A publication Critical patent/MX9401347A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/64—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms, e.g. histidine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
    • A61K8/65—Collagen; Gelatin; Keratin; Derivatives or degradation products thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/12—Ophthalmic agents for cataracts
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/14—Decongestants or antiallergics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q17/00—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
    • A61Q17/04—Topical preparations for affording protection against sunlight or other radiation; Topical sun tanning preparations
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/52—Stabilizers
    • A61K2800/522—Antioxidants; Radical scavengers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q17/00—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A61Q19/002—Aftershave preparations
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A61Q19/08—Anti-ageing preparations

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Dermatology (AREA)
  • Epidemiology (AREA)
  • Birds (AREA)
  • Ophthalmology & Optometry (AREA)
  • Immunology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Pulmonology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)

Abstract

La invención se relaciona con un producto seudodipéptido obtenido mediante acoplamiento entre la histamina o la histamina metil-substituida y un ácido aminado que tiene la fórmula siguiente: en la cual A representa un radical seleccionado en el grupo que consiste de radicales aminas, amidas, lactamas, uretanos; R1, R'1, R2, R'2....Rn, R'n representa, cada uno, un átomo de hidrógeno, un radical hidrocarbonado, o un grupo funcional; Y y Z representan, cada uno, un átomo de hidrógeno o de flúor, o un radical hidrocarbonado que puede substituirse por uno o varios grupos funcionales; y n es un entero superior o igual a 1; el enlace covalente con la histamina o la histamina metil-substituida, es un enlace peptídico entre el radical carboxílico del ácido aminado y el radical amina de la histamina. Los productos seudo-dipéptidos de la invención pueden utilizarse en aplicaciones terapéuticas, cosmetológicas y agroalimentarias y en particular para el tratamiento de la catarata.
MX9401347A 1993-02-22 1994-02-22 Producto de acoplamiento de la histamina o de la histamina metil substituida y de un acido aminado, procedimiento de preparacion y aplicaciones terapeuticas, cosmetogoligas y agroalimentarias. MX9401347A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9302295A FR2701947B1 (fr) 1993-02-22 1993-02-22 Produit de couplage de l'histamine et d'un acide aminé, procédé de préparation, et applications thérapeutiques et cosmétologiques.
FR9310486A FR2701948B1 (fr) 1993-02-22 1993-08-30 Produit de couplage de l'histamine ou l'histamine méthyl-substituée et d'un acide aminé, procédé de préparation et applications thérapeutiques, cosmétologiques et agroalimentaires.

Publications (1)

Publication Number Publication Date
MX9401347A true MX9401347A (es) 1994-08-31

Family

ID=26230131

Family Applications (1)

Application Number Title Priority Date Filing Date
MX9401347A MX9401347A (es) 1993-02-22 1994-02-22 Producto de acoplamiento de la histamina o de la histamina metil substituida y de un acido aminado, procedimiento de preparacion y aplicaciones terapeuticas, cosmetogoligas y agroalimentarias.

Country Status (11)

Country Link
US (1) US5792784A (es)
EP (1) EP0684944B1 (es)
JP (1) JP3373852B2 (es)
BR (1) BR9406126A (es)
DE (1) DE69427814T2 (es)
ES (1) ES2161758T3 (es)
FR (1) FR2701948B1 (es)
GR (1) GR3036979T3 (es)
MX (1) MX9401347A (es)
RU (1) RU2166510C2 (es)
WO (1) WO1994019325A1 (es)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2711990B1 (fr) * 1993-11-05 1995-12-08 Exsymol Sa Produit pseudodipeptide possédant un groupement imidazole, et applications thérapeutiques, cosmétologiques et agroalimentaires.
CA2187482A1 (en) * 1995-10-13 1997-04-14 Eri Inoue Pharmaceutical composition
JP3877807B2 (ja) * 1996-07-03 2007-02-07 ゼリア新薬工業株式会社 口内炎治療・予防剤
RU2141483C1 (ru) * 1997-07-04 1999-11-20 Небольсин Владимир Евгеньевич Производные пептидов или их фармацевтически приемлемые соли, способ их получения, применение и фармацевтическая композиция
AU742237B2 (en) * 1998-07-14 2001-12-20 Alcon Manufacturing Limited Use of 11-(3-dimenthylaminopropylidene)-6,11-dihydrodibenz (B,E)oxepin-2-acetic acid for the manufacture of medicament for treating non-allergic opthalmic inflammatory disorders and for the prevention of ocular neovascularization
FR2794974B1 (fr) * 1999-06-16 2001-08-17 Exsymol Sa Composition cosmetique pour l'amincissement a base de l-arginine, d'un analogue de l-arginine ou d'un de leurs derives, applicable par voie topique
AUPQ515000A0 (en) * 2000-01-19 2000-02-10 Grigg, Geoffrey Walter Treatment of uv induced immunosuppression
DE50214837D1 (de) * 2001-09-06 2011-02-10 Lonza Ag Verfahren zur herstellung von beta-alaninamiden
US20030149090A1 (en) * 2001-11-06 2003-08-07 Gehlsen Kurt R. Compositions for the treatment of infectious diseases
JP2003171276A (ja) * 2001-11-30 2003-06-17 Menicon Co Ltd 眼精疲労改善眼科用組成物
WO2004028536A1 (en) * 2002-09-30 2004-04-08 Babizhayev Mark A Method for topical treatment of eye disease and composition and device for said treatment
MC200060A1 (fr) * 2002-10-04 2003-05-28 M Exsymol Sa Produit de couplage entre la tryptamine et un alpha-aminoacide son procédé de préparation et son application dans le domaine de la neuro-cosmétique
JPWO2004064866A1 (ja) 2003-01-20 2006-05-18 イノヴェイティブ ヴィジョン プロダクツ インコーポレーテッド カルノシナーゼ阻害剤とｌ−カルノシン類との併用および組成物
AU2003226582A1 (en) * 2003-04-18 2004-11-04 Institut National De La Sante Et De La Recherche Medicale (Inserm) Use of beta-aminoisobutyric acid for the treatment of diseases linked to the accumulation of triglycerides and cholesterol
US20060275278A1 (en) * 2005-06-02 2006-12-07 Choy Camus K M Method and ophthalmic formulation for eye protection or treatment
FR2980377B1 (fr) * 2011-09-22 2013-10-04 Total Raffinage Marketing Procede de regeneration d'un catalyseur enzymatique
US8883857B2 (en) 2012-12-07 2014-11-11 Baylor College Of Medicine Small molecule xanthine oxidase inhibitors and methods of use
JP6326601B2 (ja) 2013-03-13 2018-05-23 アンティース ソシエテ アノニム 皮膚更新のためのペプチド及び前記ペプチドを使用する方法
FR3030523B1 (fr) * 2014-12-18 2017-01-20 Oreal Nouveaux composes de la famille des n-acylamino-amides,compositions les comprenant, et utilisations
CN110981810A (zh) * 2019-12-19 2020-04-10 东莞市维琪科技有限公司 一种脱羧肌肽的合成方法
CN114213336A (zh) * 2021-12-24 2022-03-22 深圳瑞德林生物技术有限公司 β-丙氨酰-L-组氨的制备方法
CN114250204B (zh) * 2021-12-29 2024-02-09 深圳瑞德林生物技术有限公司 一种羧酸还原酶突变体及酶法合成脱羧肌肽的方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4381239A (en) * 1981-02-10 1983-04-26 Tanabe Seiyaku Co., Ltd. Method for reducing the pyrogen content of or removing pyrogens from substances contaminated therewith
IT1206078B (it) * 1987-06-03 1989-04-14 Polifarma Spa Procedimento per la produzione di acido 3-indolpiruvico e suoi derivati loro uso farmaceutico
WO1989003842A1 (en) * 1987-10-21 1989-05-05 The Upjohn Company Renin inhibitors containing a (1-amino-2-hydroxy-2-heterocyclic) ethyl moiety
EP0571390B1 (en) 1990-11-23 2000-03-08 Peptech Limited The delay, prevention and/or reversal of cell senescence
DE69231576T2 (de) * 1991-09-09 2001-06-13 Peptech Ltd Verwendung von Peptiden ZUR BEHANDLUNG VON KOMPLIKATIONEN UND PATHOLOGY BEI DIABETES

Also Published As

Publication number Publication date
EP0684944B1 (fr) 2001-07-25
WO1994019325A1 (fr) 1994-09-01
US5792784A (en) 1998-08-11
JP3373852B2 (ja) 2003-02-04
FR2701948A1 (fr) 1994-09-02
DE69427814T2 (de) 2002-04-04
FR2701948B1 (fr) 1996-07-26
JPH08506825A (ja) 1996-07-23
RU2166510C2 (ru) 2001-05-10
ES2161758T3 (es) 2001-12-16
DE69427814D1 (de) 2001-08-30
GR3036979T3 (en) 2002-01-31
BR9406126A (pt) 1996-02-13
EP0684944A1 (fr) 1995-12-06

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