ES2159647T3 - Factor neurotrofico derivado de neurogliocitos como agente neuroprotector. - Google Patents
Factor neurotrofico derivado de neurogliocitos como agente neuroprotector.Info
- Publication number
- ES2159647T3 ES2159647T3 ES95935548T ES95935548T ES2159647T3 ES 2159647 T3 ES2159647 T3 ES 2159647T3 ES 95935548 T ES95935548 T ES 95935548T ES 95935548 T ES95935548 T ES 95935548T ES 2159647 T3 ES2159647 T3 ES 2159647T3
- Authority
- ES
- Spain
- Prior art keywords
- neurotrophic factor
- neurogliocits
- neuroprotector
- agent
- gdnf
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/18—Growth factors; Growth regulators
- A61K38/185—Nerve growth factor [NGF]; Brain derived neurotrophic factor [BDNF]; Ciliary neurotrophic factor [CNTF]; Glial derived neurotrophic factor [GDNF]; Neurotrophins, e.g. NT-3
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Veterinary Medicine (AREA)
- Biomedical Technology (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Epidemiology (AREA)
- Immunology (AREA)
- Gastroenterology & Hepatology (AREA)
- Zoology (AREA)
- Psychology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pain & Pain Management (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Steroid Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Abstract
LA PRESENTE INVENCION SE DIRIGE AL USO DE UN FACTOR NEUROTROFICO DERIVADO DE GLIAL (GDNF) PARA INHIBIR O PREVENIR LA ACTIVIDAD DE LOS BROTES. LOS METODOS DE LA PRESENTE INVENCION SE LLEVAN A CABO MEDIANTE LA ADMINISTRACION DE GDNF A PACIENTES QUE TIENE O PUEDEN TENER UNA ENFERMEDAD NEURODEGENERATIVA COMO LA EPILEPSIA. TAMBIEN SE FACILITAN COMPOSICIONES FARMACEUTICAS QUE CONTIENEN UAN CANTIDAD EFECTIVA TERAPEUTICAMENTE DE GDNF EN UN VEHICULO ACEPTABLE FARMACEUTICAMENTE.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US34082194A | 1994-11-15 | 1994-11-15 |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2159647T3 true ES2159647T3 (es) | 2001-10-16 |
Family
ID=23335068
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES95935548T Expired - Lifetime ES2159647T3 (es) | 1994-11-15 | 1995-11-13 | Factor neurotrofico derivado de neurogliocitos como agente neuroprotector. |
Country Status (13)
Country | Link |
---|---|
US (1) | US5733875A (es) |
EP (1) | EP0792160B1 (es) |
JP (1) | JPH10508839A (es) |
AT (1) | ATE205088T1 (es) |
AU (1) | AU691349B2 (es) |
CA (1) | CA2204911C (es) |
DE (1) | DE69522578T2 (es) |
DK (1) | DK0792160T3 (es) |
ES (1) | ES2159647T3 (es) |
IL (1) | IL115966A (es) |
PT (1) | PT792160E (es) |
WO (1) | WO1996014861A1 (es) |
ZA (1) | ZA959714B (es) |
Families Citing this family (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6184200B1 (en) * | 1995-09-28 | 2001-02-06 | Amgen Inc. | Truncated glial cell line-derived neurotrophic factor |
US5641750A (en) * | 1995-11-29 | 1997-06-24 | Amgen Inc. | Methods for treating photoreceptors using glial cell line-derived neurotrophic factor (GDNF) protein product |
US5641749A (en) * | 1995-11-29 | 1997-06-24 | Amgen Inc. | Method for treating retinal ganglion cell injury using glial cell line-derived neurothrophic factor (GDNF) protein product |
WO1997019693A1 (en) * | 1995-11-29 | 1997-06-05 | Amgen Inc. | Method for treating sensory neuropathy using glial cell line-derived neurotrophic factor (gdnf) protein product |
US6677135B1 (en) | 1996-05-08 | 2004-01-13 | Biogen, Inc. | Ret ligand (RetL) for stimulating neutral and renal growth |
BR9713055A (pt) | 1996-11-15 | 2000-04-04 | Genentech Inc | Processo para isolar uma neurotrofina humana recombinante, composição de neurotrofina e processo para purificar uma neurotrofina |
US6277820B1 (en) | 1998-04-09 | 2001-08-21 | Genentech, Inc. | Method of dopaminergic and serotonergic neuron formation from neuroprogenitor cells |
PT1223966E (pt) * | 1999-10-29 | 2003-09-30 | Biopharm Ges Biotechn Entwickl | Utilizacao do gdnf para tratamento de defeitos na cornea |
US20040197900A1 (en) * | 2003-04-04 | 2004-10-07 | Arnon Rosenthal | Foggy |
BRPI0710800A2 (pt) * | 2006-04-25 | 2012-01-17 | Univ California | administração de fatores de crescimento para o tratamento de distúrbios de snc |
JP2009535360A (ja) * | 2006-04-26 | 2009-10-01 | ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア | 高分子量神経治療薬の対流増加送達のための組成物および方法 |
US8461389B2 (en) | 2008-04-18 | 2013-06-11 | University College Dublin, National University Of Ireland, Dublin | Psycho-pharmaceuticals |
WO2014152511A1 (en) | 2013-03-15 | 2014-09-25 | The Jackson Laboratory | Methods for promoting wound healing and hair growth |
US11602513B1 (en) | 2016-07-22 | 2023-03-14 | Flamel Ireland Limited | Modified release gamma-hydroxybutyrate formulations having improved pharmacokinetics |
AU2017357931A1 (en) | 2016-11-10 | 2019-06-20 | Keros Therapeutics, Inc. | GDNF fusion polypeptides and methods of use thereof |
EP3973979A1 (en) * | 2020-09-25 | 2022-03-30 | The Provost, Fellows, Foundation Scholars, and The Other Members of Board, of The College of The Holy and Undivided Trinity of Queen Elizabeth | A tight junction (zonulae occludentes) protein for use in treating or preventing epilepsy |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
HU220795B1 (hu) * | 1991-09-20 | 2002-05-28 | Amgen Inc. | Gliasejtvonal-eredetű neurotróf faktorfehérjék, továbbá berendezések és gyógyászati készítmények idegsejtkárosodás megelőzésére és kezelésére |
FR2717824B1 (fr) * | 1994-03-25 | 1996-04-26 | Rhone Poulenc Rorer Sa | Virus recombinants, préparation et utilisation en thérapie génique. |
-
1995
- 1995-05-22 US US08/446,383 patent/US5733875A/en not_active Expired - Lifetime
- 1995-11-12 IL IL11596695A patent/IL115966A/xx not_active IP Right Cessation
- 1995-11-13 DK DK95935548T patent/DK0792160T3/da active
- 1995-11-13 JP JP8515884A patent/JPH10508839A/ja not_active Ceased
- 1995-11-13 WO PCT/IB1995/001004 patent/WO1996014861A1/en active IP Right Grant
- 1995-11-13 ES ES95935548T patent/ES2159647T3/es not_active Expired - Lifetime
- 1995-11-13 AT AT95935548T patent/ATE205088T1/de not_active IP Right Cessation
- 1995-11-13 AU AU37528/95A patent/AU691349B2/en not_active Expired
- 1995-11-13 PT PT95935548T patent/PT792160E/pt unknown
- 1995-11-13 EP EP95935548A patent/EP0792160B1/en not_active Expired - Lifetime
- 1995-11-13 DE DE69522578T patent/DE69522578T2/de not_active Expired - Fee Related
- 1995-11-13 CA CA002204911A patent/CA2204911C/en not_active Expired - Fee Related
- 1995-11-15 ZA ZA9509714A patent/ZA959714B/xx unknown
Also Published As
Publication number | Publication date |
---|---|
AU691349B2 (en) | 1998-05-14 |
EP0792160B1 (en) | 2001-09-05 |
CA2204911C (en) | 2002-07-23 |
IL115966A (en) | 1999-11-30 |
WO1996014861A1 (en) | 1996-05-23 |
ATE205088T1 (de) | 2001-09-15 |
DE69522578D1 (de) | 2001-10-11 |
US5733875A (en) | 1998-03-31 |
PT792160E (pt) | 2002-02-28 |
AU3752895A (en) | 1996-06-06 |
JPH10508839A (ja) | 1998-09-02 |
DE69522578T2 (de) | 2002-07-11 |
IL115966A0 (en) | 1996-01-31 |
CA2204911A1 (en) | 1996-05-23 |
DK0792160T3 (da) | 2001-11-19 |
EP0792160A1 (en) | 1997-09-03 |
ZA959714B (en) | 1997-10-15 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FG2A | Definitive protection |
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