ES2154828T3 - Uso de derivados de fenoxipiridina para el tratamiento de enfermedades causadas por trastornos del sistema dopamina. - Google Patents

Uso de derivados de fenoxipiridina para el tratamiento de enfermedades causadas por trastornos del sistema dopamina.

Info

Publication number
ES2154828T3
ES2154828T3 ES96921928T ES96921928T ES2154828T3 ES 2154828 T3 ES2154828 T3 ES 2154828T3 ES 96921928 T ES96921928 T ES 96921928T ES 96921928 T ES96921928 T ES 96921928T ES 2154828 T3 ES2154828 T3 ES 2154828T3
Authority
ES
Spain
Prior art keywords
alkyl
carbonyl
amino
hydrogen
treatment
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES96921928T
Other languages
English (en)
Inventor
Thierry Godel
Deborah Hartman
Claus Riemer
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
F Hoffmann La Roche AG
Original Assignee
F Hoffmann La Roche AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by F Hoffmann La Roche AG filed Critical F Hoffmann La Roche AG
Application granted granted Critical
Publication of ES2154828T3 publication Critical patent/ES2154828T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4418—Non condensed pyridines; Hydrogenated derivatives thereof having a carbocyclic group directly attached to the heterocyclic ring, e.g. cyproheptadine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia

Landscapes

  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Psychiatry (AREA)
  • Neurology (AREA)
  • Organic Chemistry (AREA)
  • Neurosurgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pyridine Compounds (AREA)

Abstract

LA INVENCION SE REFIERE AL USO DE COMPUESTOS DE FORMULA GENERAL (I), EN DONDE R SUP,1} SIGNIFICA HIDROGENO, ALQUILO INFERIOR, HALOGENO, ALCOXI INFERIOR O NITRO; R SUP,2} SIGNIFICA HIDROGENO, ALQUILO INFERIOR O TRIFLUOROMETILO; Y R SUP,3} SIGNIFICA HIDROGENO, ALQUILO INFERIOR, TRIFLUOROMETILO, BENCILO, HIDROXI ALQUILO INFERIOR, ALCOXI INFERIOR, ALQUIL INFERIOR - CARBONIL AMINO, CARBONIL - ALQUILO INFERIOR, BENCILO, DI - ALQUIL INFERIOR - AMINO - CARBONILO, CARBONILAMINO O AMINO - CARBONIL AMINO; O R SUP,2} Y R SUP,3} JUNTOS OPCIONALMENTE SIGNIFICAN UN ANILLO BENCENO FUNDIDO Y R SUP,4} SIGNIFICA HIDROGENO O HALOGENO, ASI COMO TAMBIEN SALES FARMACEUTICAMENTE ACEPTABLES DE COMPUESTOS DE LA FORMULA GENERAL (I), PARA EL TRATAMIENTO O LA PROFILAXIS DE ENFERMEDADES PRODUCIDAS POR TRASTORNOS DEL SISTEMA DE LA DOPAMINA Y, RESPECTIVAMENTE, PARA LA PRODUCCION DE LOS MEDICAMENTOS CORRESPONDIENTES.
ES96921928T 1995-06-09 1996-06-04 Uso de derivados de fenoxipiridina para el tratamiento de enfermedades causadas por trastornos del sistema dopamina. Expired - Lifetime ES2154828T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH170495 1995-06-09

Publications (1)

Publication Number Publication Date
ES2154828T3 true ES2154828T3 (es) 2001-04-16

Family

ID=4216657

Family Applications (1)

Application Number Title Priority Date Filing Date
ES96921928T Expired - Lifetime ES2154828T3 (es) 1995-06-09 1996-06-04 Uso de derivados de fenoxipiridina para el tratamiento de enfermedades causadas por trastornos del sistema dopamina.

Country Status (14)

Country Link
US (1) US5698565A (es)
EP (1) EP0837680B1 (es)
JP (1) JP3004732B2 (es)
AT (1) ATE198984T1 (es)
AU (1) AU6300396A (es)
BR (1) BR9609196A (es)
CA (1) CA2222226A1 (es)
DE (1) DE69611727T2 (es)
DK (1) DK0837680T3 (es)
ES (1) ES2154828T3 (es)
GR (1) GR3035703T3 (es)
PT (1) PT837680E (es)
TR (1) TR199701577T1 (es)
WO (1) WO1996041629A1 (es)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TR199801774T2 (xx) * 1996-03-08 1998-12-21 F.Hoffmann-La Roche Ag 4-fenil-3, 6-dihidro-2H- piridil t�revlerinin, NMDA resept�r alttip blokerleri olarak kullan�m�.

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL133317C (es) * 1966-06-24 1900-01-01
US3816434A (en) * 1966-06-24 1974-06-11 Hoffmann La Roche 4-(3-(4-phenyl-piperidino)-2-hydroxy-propoxy)-benzophenones
CH474511A (es) * 1966-06-24 1969-06-30 F. Hoffmann-La Roche & Co. Aktiengesellschaft
CH506525A (de) * 1968-12-24 1971-04-30 Hoffmann La Roche Verfahren zur Herstellung von aromatischen Äthern
CH558354A (de) * 1970-06-17 1975-01-31 Hoffmann La Roche Verfahren zur herstellung von aromatischen aethern.
JPS57145872A (en) * 1981-03-05 1982-09-09 Otsuka Pharmaceut Co Ltd Carbostyrile derivative
FR2662355B1 (fr) * 1990-05-22 1994-11-10 Sanofi Sa Utilisation de la 1-[2-(2-naphtyl)ethyl]-4-(3-trifluoromethylphenyl)-1,2,3,6-tetrahydropyridine pour la preparation de medicaments destines au traitement de troubles cerebraux et neuronaux.
HU211019B (en) * 1991-12-02 1995-09-28 Richter Gedeon Vegyeszet Process for producing new 1,2,3,6-tetrahydropyridine and piperidine derivatives substituted with n-(hydroxylalkyl) group and compositions comprising such compounds

Also Published As

Publication number Publication date
EP0837680B1 (en) 2001-01-31
ATE198984T1 (de) 2001-02-15
DE69611727D1 (de) 2001-03-08
BR9609196A (pt) 1999-05-11
DK0837680T3 (da) 2001-05-07
US5698565A (en) 1997-12-16
AU6300396A (en) 1997-01-09
JP3004732B2 (ja) 2000-01-31
PT837680E (pt) 2001-07-31
TR199701577T1 (xx) 1998-06-22
JPH10506651A (ja) 1998-06-30
DE69611727T2 (de) 2001-08-23
CA2222226A1 (en) 1996-12-27
WO1996041629A1 (en) 1996-12-27
MX9709393A (es) 1998-07-31
EP0837680A1 (en) 1998-04-29
GR3035703T3 (en) 2001-07-31

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