ES2154285T3 - Utilizacion de derivados de la beta-naftoquinona para la aceleracion de la proliferacion de las celulas endoteliales y de la inhibicion de las no-sintasas. - Google Patents

Utilizacion de derivados de la beta-naftoquinona para la aceleracion de la proliferacion de las celulas endoteliales y de la inhibicion de las no-sintasas.

Info

Publication number
ES2154285T3
ES2154285T3 ES94401460T ES94401460T ES2154285T3 ES 2154285 T3 ES2154285 T3 ES 2154285T3 ES 94401460 T ES94401460 T ES 94401460T ES 94401460 T ES94401460 T ES 94401460T ES 2154285 T3 ES2154285 T3 ES 2154285T3
Authority
ES
Spain
Prior art keywords
proliferation
beta
derivatives
syntheases
naftoquinone
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES94401460T
Other languages
English (en)
Inventor
Christian Bloy
Jean-Pierre Cazenave
Bernard Hercelin
Bernard Teisseire
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Aventis Pharma SA
Original Assignee
Aventis Pharma SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aventis Pharma SA filed Critical Aventis Pharma SA
Application granted granted Critical
Publication of ES2154285T3 publication Critical patent/ES2154285T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/12—Ketones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/17—Amides, e.g. hydroxamic acids having the group >N—C(O)—N< or >N—C(S)—N<, e.g. urea, thiourea, carmustine
    • A61K31/175—Amides, e.g. hydroxamic acids having the group >N—C(O)—N< or >N—C(S)—N<, e.g. urea, thiourea, carmustine having the group, >N—C(O)—N=N— or, e.g. carbonohydrazides, carbazones, semicarbazides, semicarbazones; Thioanalogues thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P41/00—Drugs used in surgical methods, e.g. surgery adjuvants for preventing adhesion or for vitreum substitution
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/10—Antioedematous agents; Diuretics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/14—Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers

Abstract

UTILIZACION DE DERIVADOS DE LA BETA MULA (I): EN LA CUAL R ES UN GRUPO EDICAMENTO QUE PERMITA ACELERAR LA PROLIFERACION DE LAS CELULAS ENDOTELIALES E INHIBIR LAS NO SINTASAS.
ES94401460T 1993-07-02 1994-06-28 Utilizacion de derivados de la beta-naftoquinona para la aceleracion de la proliferacion de las celulas endoteliales y de la inhibicion de las no-sintasas. Expired - Lifetime ES2154285T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9308111A FR2707494B1 (fr) 1993-07-02 1993-07-02 Nouvelle utilisation de dérivés de la béta-naphtoquinone ainsi que de leurs sels.

Publications (1)

Publication Number Publication Date
ES2154285T3 true ES2154285T3 (es) 2001-04-01

Family

ID=9448827

Family Applications (1)

Application Number Title Priority Date Filing Date
ES94401460T Expired - Lifetime ES2154285T3 (es) 1993-07-02 1994-06-28 Utilizacion de derivados de la beta-naftoquinona para la aceleracion de la proliferacion de las celulas endoteliales y de la inhibicion de las no-sintasas.

Country Status (13)

Country Link
US (1) US5478821A (es)
EP (1) EP0631776B1 (es)
JP (1) JP3993647B2 (es)
AT (1) ATE197668T1 (es)
CA (1) CA2127214C (es)
DE (1) DE69426316T2 (es)
DK (1) DK0631776T3 (es)
ES (1) ES2154285T3 (es)
FR (1) FR2707494B1 (es)
GR (1) GR3035059T3 (es)
HU (1) HU214716B (es)
PT (1) PT631776E (es)
RU (1) RU2131246C1 (es)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK0758890T3 (da) 1994-05-11 2005-04-18 Jes Olesen Anvendelse af NO indfangere, inhibitorer eller antagonister ved behandling af migræne
FR2722507B1 (fr) * 1994-07-12 1996-08-14 Rhone Poulenc Rorer Sa Adenovirus comportant un gene codant pour une no synthase
CA2229074A1 (en) * 1995-08-09 1997-02-20 Ontogen Corporation Nitric oxide synthase (nos) inhibitors
EP0969790A2 (de) * 1997-02-21 2000-01-12 Beiersdorf Aktiengesellschaft Zubereitungen für die behandlung von rosacea
IT1312537B1 (it) * 1999-04-16 2002-04-22 Euphar Group Srl Derivati del (-)- verbenone.
JP4989830B2 (ja) * 1999-07-21 2012-08-01 サーントゥル ナシオナル ドゥ ラ ルシェルシュ シャーンティフィク 脳によるグルタミン酸塩の放出に対して抑制効果を示す薬剤を製造するためのベータ−ナフトキノン誘導体の使用
WO2018156917A1 (en) * 2017-02-23 2018-08-30 The Cleveland Clinic Foundation Anti-aging compounds

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR924M (es) * 1959-09-26 1961-11-13
US3758520A (en) * 1971-07-23 1973-09-11 C Beaudet Process for the preparation of beta-naphthoquinone semicarbazone
JPH037806A (ja) * 1989-06-05 1991-01-16 Masamoto Kaneko 廃棄物の処理方法及び装置

Also Published As

Publication number Publication date
ATE197668T1 (de) 2000-12-15
HU9401977D0 (en) 1994-09-28
DK0631776T3 (da) 2001-03-05
CA2127214A1 (fr) 1995-01-03
JPH07145129A (ja) 1995-06-06
EP0631776A1 (fr) 1995-01-04
JP3993647B2 (ja) 2007-10-17
DE69426316T2 (de) 2001-05-03
PT631776E (pt) 2001-05-31
GR3035059T3 (en) 2001-03-30
HUT70507A (en) 1995-10-30
US5478821A (en) 1995-12-26
EP0631776B1 (fr) 2000-11-22
HU214716B (hu) 1998-05-28
RU94022756A (ru) 1996-09-10
CA2127214C (fr) 2004-10-26
FR2707494A1 (fr) 1995-01-20
FR2707494B1 (fr) 1995-08-25
DE69426316D1 (de) 2000-12-28
RU2131246C1 (ru) 1999-06-10

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