ES2152065T3 - Unidades de dosificado de esteroides con un recubrimiento estanco a los esteroides. - Google Patents

Unidades de dosificado de esteroides con un recubrimiento estanco a los esteroides.

Info

Publication number
ES2152065T3
ES2152065T3 ES97202908T ES97202908T ES2152065T3 ES 2152065 T3 ES2152065 T3 ES 2152065T3 ES 97202908 T ES97202908 T ES 97202908T ES 97202908 T ES97202908 T ES 97202908T ES 2152065 T3 ES2152065 T3 ES 2152065T3
Authority
ES
Spain
Prior art keywords
steroids
steroid
surface layer
composition
dosage units
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES97202908T
Other languages
English (en)
Inventor
Gertjan Peter Hartholt
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Akzo Nobel NV
Original Assignee
Akzo Nobel NV
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Akzo Nobel NV filed Critical Akzo Nobel NV
Application granted granted Critical
Publication of ES2152065T3 publication Critical patent/ES2152065T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A61K31/568—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in positions 10 and 13 by a chain having at least one carbon atom, e.g. androstanes, e.g. testosterone
    • A61K31/569—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in positions 10 and 13 by a chain having at least one carbon atom, e.g. androstanes, e.g. testosterone substituted in position 17 alpha, e.g. ethisterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/575—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of three or more carbon atoms, e.g. cholane, cholestane, ergosterol, sitosterol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806—Coating materials
    • A61K9/282—Organic compounds, e.g. fats
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806—Coating materials
    • A61K9/2833—Organic macromolecular compounds
    • A61K9/284—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone
    • A61K9/2846—Poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/18—Feminine contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Endocrinology (AREA)
  • Diabetes (AREA)
  • Reproductive Health (AREA)
  • Gynecology & Obstetrics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Steroid Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Materials For Medical Uses (AREA)
  • Medicines Containing Plant Substances (AREA)

Abstract

UNAS UNIDADES DE DOSIS, COMO NUCLEOS DE TABLETAS Y GRANULOS, QUE CONTIENEN UNA COMPOSICION QUE INCLUYE UN ESTEROIDE CON DOS ATOMOS DE HIDROGENO EN LA POSICION 3 DEL ESQUELETO DE ESTEROIDE, SON POSTERIORMENTE RECUBIERTAS. AUNQUE EL PROCESO CONVENCIONAL DE REVESTIMIENTO CON AZUCAR REPRESENTA LA APLICACION DE VARIAS CAPAS INCLUIDA, COMO CAPA SUPERFICIAL, UNA CAPA DE AZUCAR, SE HA COMPROBADO QUE UN RECUBRIMIENTO DE CIERRE COMO EL UTILIZADO NORMALMENTE EN UN PROCESO DE REVESTIMIENTO CON AZUCAR SE PUEDE USAR COMO CAPA SUPERFICIAL CON EL FIN DE IMPEDIR LA TRANSFERENCIA DEL ESTEROIDE AL EXTERIOR DE LA COMPOSICION. GRACIAS A ESTE NUEVO USO DE UN REVESTIMIENTO DE CIERRE, SE OBTIENEN NUEVAS UNIDADES DE DOSIFICACION. EL PROCESO ES VENTAJOSO DADO QUE EXIGE UN MENOR NUMERO DE ETAPAS QUE ANTES PARA SU REALIZACION.
ES97202908T 1997-09-23 1997-09-23 Unidades de dosificado de esteroides con un recubrimiento estanco a los esteroides. Expired - Lifetime ES2152065T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP97202908A EP0927556B1 (en) 1997-09-23 1997-09-23 Dosage units of steroids with a seal coating for the steroids

Publications (1)

Publication Number Publication Date
ES2152065T3 true ES2152065T3 (es) 2001-01-16

Family

ID=8228748

Family Applications (1)

Application Number Title Priority Date Filing Date
ES97202908T Expired - Lifetime ES2152065T3 (es) 1997-09-23 1997-09-23 Unidades de dosificado de esteroides con un recubrimiento estanco a los esteroides.

Country Status (17)

Country Link
US (1) US6761907B1 (es)
EP (1) EP0927556B1 (es)
JP (1) JP2001517629A (es)
KR (1) KR100585973B1 (es)
CN (1) CN1177588C (es)
AT (1) ATE195871T1 (es)
AU (1) AU738996B2 (es)
DE (1) DE69702985T2 (es)
DK (1) DK0927556T3 (es)
ES (1) ES2152065T3 (es)
GR (1) GR3034842T3 (es)
HK (1) HK1019048A1 (es)
ID (1) ID24436A (es)
NO (1) NO327632B1 (es)
NZ (1) NZ503400A (es)
PT (1) PT927556E (es)
WO (1) WO1999015180A1 (es)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000059920A2 (en) * 1999-04-06 2000-10-12 Akzo Nobel N.V. Orally active 7.alpha.-alkyl androgens
US7303763B2 (en) * 2001-02-12 2007-12-04 Watson Laboratories, Inc. Compositions for conjugated estrogens and associated methods
TW200418525A (en) * 2002-11-20 2004-10-01 Akzo Nobel Nv Coated pharmaceutical tablets containing Tibolone
DE102009001636A1 (de) * 2009-03-18 2010-09-23 Henkel Ag & Co. Kgaa Bleichmittel mit verzögertem Bleichbeginn
KR101367551B1 (ko) * 2012-01-09 2014-02-25 박영식 과일의 수분증발을 막기 위한 피막제 도포 방법
JP2014189547A (ja) * 2013-03-28 2014-10-06 Lintec Corp 嚥下物被覆体
CN103550179B (zh) * 2013-10-31 2015-02-04 河北创健药业有限公司 一种烯丙雌醇片及其制备方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1309597A (en) * 1969-05-09 1973-03-14 Colorcon Stabilised shellac sealing coating for tablets
GB2195248A (en) * 1986-10-06 1988-04-07 Procter & Gamble Coated lipid-containing compositions
IT1213390B (it) * 1986-11-28 1989-12-20 Gipharmex Spa Composizioni farmaceutiche ad uso orale del tipo a cessione controllata nel tempo contenenti composti a struttura steroidea attivi nelle alterazioni del metabolismo del colesterolo.
NZ241613A (en) * 1991-02-27 1993-06-25 Janssen Pharmaceutica Nv Highlighting intagliations in tablets
US5395627A (en) * 1992-09-04 1995-03-07 Akzo N.V. Pharmaceutical granulate
ZA949929B (en) * 1993-12-23 1995-08-23 Akzo Nobel Nv Sugar-coated pharmaceutical dosage unit.

Also Published As

Publication number Publication date
AU738996B2 (en) 2001-10-04
EP0927556A1 (en) 1999-07-07
WO1999015180A1 (en) 1999-04-01
DE69702985T2 (de) 2001-02-15
NO20001474L (no) 2000-03-22
AU1147099A (en) 1999-04-12
KR20010024231A (ko) 2001-03-26
HK1019048A1 (en) 2000-01-21
DE69702985D1 (de) 2000-10-05
CN1271286A (zh) 2000-10-25
NO20001474D0 (no) 2000-03-22
EP0927556B1 (en) 2000-08-30
NO327632B1 (no) 2009-09-07
NZ503400A (en) 2001-11-30
JP2001517629A (ja) 2001-10-09
GR3034842T3 (en) 2001-02-28
PT927556E (pt) 2000-12-29
ID24436A (id) 2000-07-20
ATE195871T1 (de) 2000-09-15
CN1177588C (zh) 2004-12-01
KR100585973B1 (ko) 2006-06-07
DK0927556T3 (da) 2000-11-20
US6761907B1 (en) 2004-07-13

Similar Documents

Publication Publication Date Title
ATE293440T1 (de) Pulverbeschichtungszusammensetzung für elektrostatische beschichtung von pharmazeutischen substraten
JPS5367738A (en) Ultraviolet radiationncurable liquid coating composition
JPS5310384A (en) Process and apparatus for forming coating layer by cold cathodic discharge type
NL193270B (nl) Werkwijze voor het aanbrengen van een film van een vloeibare bekledingssamenstelling op een substraat.
EP0005632A3 (en) Plasma spray coating composition, method of coating articles and coated articles produced thereby
DE3265225D1 (en) Process for applying a coating composition to a substrate, and the coated substrate thus obtained
ES2152065T3 (es) Unidades de dosificado de esteroides con un recubrimiento estanco a los esteroides.
JPS53128683A (en) Polyester film having modified surface
MY8600117A (en) Dispersions useful in the coating of substrates
CA2304331A1 (en) Coated dosage units
JPS5413777A (en) Photo resist coater of semiconductor wafers
JPS5422168A (en) Glass coating method for semiconductor element
JPS52123437A (en) Material for protecting surface
JPS5222038A (en) Trowel apparatus for coating
JPS5274624A (en) Waterproof coating composition
JPS53101026A (en) Resin composition for surface finishing of construction
JPS5360942A (en) Prevention of blisters in coating film
JPS5277186A (en) Films coated with resins
JPS52823A (en) Composition for forming polyurethane layer on the surfaces of various kinds of substrates
PT67253B (en) Process for the preparation of coating compositions and thermoplastic film substrates coated therewith
JPS5586563A (en) Method of coating urethane resin bonding agent
JPS51128332A (en) A highly adhesive rust resisting paint composition
JPS54124584A (en) Coating of fluorescent substance
JPS51119726A (en) A liquid coating composition for use in forming a gloss surface
JPS5276340A (en) Composition of powder coating

Legal Events

Date Code Title Description
FG2A Definitive protection

Ref document number: 927556

Country of ref document: ES