ES2147727T3 - Polipeptido bioadhesivo sintetico. - Google Patents

Polipeptido bioadhesivo sintetico.

Info

Publication number
ES2147727T3
ES2147727T3 ES92901606T ES92901606T ES2147727T3 ES 2147727 T3 ES2147727 T3 ES 2147727T3 ES 92901606 T ES92901606 T ES 92901606T ES 92901606 T ES92901606 T ES 92901606T ES 2147727 T3 ES2147727 T3 ES 2147727T3
Authority
ES
Spain
Prior art keywords
apolar
polar
polypeptide chains
stripes
polypeptide
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES92901606T
Other languages
English (en)
Inventor
Roy H L Pang
Charles M Cohen
Peter C Keck
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Creative Biomolecules Inc
Original Assignee
Creative Biomolecules Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Creative Biomolecules Inc filed Critical Creative Biomolecules Inc
Application granted granted Critical
Publication of ES2147727T3 publication Critical patent/ES2147727T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/001—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof by chemical synthesis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L24/00—Surgical adhesives or cements; Adhesives for colostomy devices
    • A61L24/04—Surgical adhesives or cements; Adhesives for colostomy devices containing macromolecular materials
    • A61L24/10—Polypeptides; Proteins
    • A61L24/106—Fibrin; Fibrinogen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14—Macromolecular materials
    • A61L27/22—Polypeptides or derivatives thereof, e.g. degradation products
    • A61L27/227—Other specific proteins or polypeptides not covered by A61L27/222, A61L27/225 or A61L27/24
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Dermatology (AREA)
  • Surgery (AREA)
  • Molecular Biology (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Transplantation (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Materials For Medical Uses (AREA)
  • Adhesives Or Adhesive Processes (AREA)

Abstract

ESTA INVENCION PERTENECE A UNA COMPOSICION ADHESIVA SINTETICA PARA USO EN AMBIENTES ACUOSOS. LA COMPOSICION COMPRENDE CADENAS DE POLIPETIDOS QUE TIENEN UNA ESTRUCTURA HELICOIDAL (ALFA) EN AMBIENTES ACUOSOS Y ES CAPAZ DE INTERACCIONES COHESIVAS Y ADHESIVAS. LAS CADENAS DE POLIPETIDOS COMPRENDEN ACIDOS AMINO POLARES Y APOLARES, ESTANDO DISPUESTOS LOS ACIDOS AMINO POLARES Y APOLARES PARA DEFINIR BANDAS EN ESPIRAL VERTICAL APOLARES Y POLARES SOBRE LA SUPERFICIE DE LA HELICE. LAS BANDAS APOLARES PERMITEN A LAS CADENAS DE POLIPEPTIDOS REUNIRSE EN ESTRUCTURAS SUPERHELICOIDALES Y LAS BANDAS POLARES PERMITEN ENLACE CRUZADO ENTRE CADENAS DENTRO Y ENTRE LAS ESTRUCTURAS SUPERHELICOIDALES.
ES92901606T 1990-12-14 1991-12-10 Polipeptido bioadhesivo sintetico. Expired - Lifetime ES2147727T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/627,323 US5197973A (en) 1990-12-14 1990-12-14 Synthetic bioadhesive

Publications (1)

Publication Number Publication Date
ES2147727T3 true ES2147727T3 (es) 2000-10-01

Family

ID=24514195

Family Applications (1)

Application Number Title Priority Date Filing Date
ES92901606T Expired - Lifetime ES2147727T3 (es) 1990-12-14 1991-12-10 Polipeptido bioadhesivo sintetico.

Country Status (9)

Country Link
US (2) US5197973A (es)
EP (1) EP0563172B1 (es)
JP (1) JPH06507304A (es)
AT (1) ATE194650T1 (es)
AU (1) AU656354B2 (es)
CA (1) CA2098303C (es)
DE (1) DE69132315T2 (es)
ES (1) ES2147727T3 (es)
WO (1) WO1992010567A1 (es)

Families Citing this family (51)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1993015110A1 (en) * 1992-01-31 1993-08-05 Whitehead Institute For Biomedical Research Amino acid sequences which pair specifically
US5942496A (en) 1994-02-18 1999-08-24 The Regent Of The University Of Michigan Methods and compositions for multiple gene transfer into bone cells
US6551618B2 (en) 1994-03-15 2003-04-22 University Of Birmingham Compositions and methods for delivery of agents for neuronal regeneration and survival
US5710252A (en) * 1995-02-03 1998-01-20 Eastman Kodak Company Method for recombinant yeast expression and isolation of water-soluble collagen-type polypeptides
US5670616A (en) * 1995-02-03 1997-09-23 Eastman Kodak Company Collagen-like polypeptides and biopolymers and nucleic acids encoding same
US7204848B1 (en) * 1995-03-01 2007-04-17 Boston Scientific Scimed, Inc. Longitudinally flexible expandable stent
US5817303A (en) * 1995-05-05 1998-10-06 Protein Polymer Technologies, Inc. Bonding together tissue with adhesive containing polyfunctional crosslinking agent and protein polymer
US5733868A (en) * 1996-04-16 1998-03-31 Depuy Orthopaedics, Inc. Poly(amino acid) adhesive tissue grafts
US5932539A (en) * 1996-10-15 1999-08-03 The Board Of Trustees Of The University Of Illinois Biodegradable polymer matrix for tissue repair
DE19755023C2 (de) * 1997-12-11 2000-03-09 Celanese Chem Europe Gmbh Katalysator und Verfahren zur Herstellung von Vinylacetat
US6217527B1 (en) 1998-09-30 2001-04-17 Lumend, Inc. Methods and apparatus for crossing vascular occlusions
US20020022588A1 (en) * 1998-06-23 2002-02-21 James Wilkie Methods and compositions for sealing tissue leaks
US7078232B2 (en) * 1999-08-19 2006-07-18 Artecel, Inc. Adipose tissue-derived adult stem or stromal cells for the repair of articular cartilage fractures and uses thereof
US6429013B1 (en) * 1999-08-19 2002-08-06 Artecel Science, Inc. Use of adipose tissue-derived stromal cells for chondrocyte differentiation and cartilage repair
JP2002171026A (ja) * 2000-11-30 2002-06-14 Sony Corp 多重巻らせん構造体および機能材料
US8815793B2 (en) * 2001-07-20 2014-08-26 Northwestern University Polymeric compositions and related methods of use
US7858679B2 (en) * 2001-07-20 2010-12-28 Northwestern University Polymeric compositions and related methods of use
US7618937B2 (en) * 2001-07-20 2009-11-17 Northwestern University Peptidomimetic polymers for antifouling surfaces
US6758836B2 (en) 2002-02-07 2004-07-06 C. R. Bard, Inc. Split tip dialysis catheter
US20080171012A1 (en) * 2007-01-11 2008-07-17 Phillip Messersmith Fouling Resistant Coatings and Methods of Making Same
US8911831B2 (en) * 2002-07-19 2014-12-16 Northwestern University Surface independent, surface-modifying, multifunctional coatings and applications thereof
US9101536B2 (en) 2002-08-06 2015-08-11 Matrix Medical Llc Biocompatible phase invertable proteinaceous compositions and methods for making and using the same
US10098981B2 (en) 2002-08-06 2018-10-16 Baxter International Inc. Biocompatible phase invertable proteinaceous compositions and methods for making and using the same
US7393339B2 (en) * 2003-02-21 2008-07-01 C. R. Bard, Inc. Multi-lumen catheter with separate distal tips
US20040243095A1 (en) 2003-05-27 2004-12-02 Shekhar Nimkar Methods and apparatus for inserting multi-lumen spit-tip catheters into a blood vessel
CA2545874C (en) 2003-10-06 2012-02-21 3F Therapeutics, Inc. Minimally invasive valve replacement system
US20050075718A1 (en) 2003-10-06 2005-04-07 Nguyen Tuoc Tan Minimally invasive valve replacement system
US20050125033A1 (en) * 2003-12-04 2005-06-09 Mcnally-Heintzelman Karen M. Wound closure apparatus
US20050125015A1 (en) * 2003-12-04 2005-06-09 Mcnally-Heintzelman Karen M. Tissue-handling apparatus, system and method
US8992454B2 (en) 2004-06-09 2015-03-31 Bard Access Systems, Inc. Splitable tip catheter with bioresorbable adhesive
DE102004031258A1 (de) * 2004-06-29 2006-02-09 Jennissen, Herbert P., Prof. Dr. Proteinhybride mit polyhydroxyaromatischen Aminosäure-Epitopen
US7825083B2 (en) * 2005-02-10 2010-11-02 Spine Wave, Inc. Synovial fluid barrier
US8636986B2 (en) * 2005-11-18 2014-01-28 The Forsyth Institute Treatment and prevention of bone loss using resolvins
US7732539B2 (en) * 2006-02-16 2010-06-08 National Science Foundation Modified acrylic block copolymers for hydrogels and pressure sensitive wet adhesives
US8563117B2 (en) * 2006-08-04 2013-10-22 Phillip B. Messersmith Biomimetic modular adhesive complex: materials, methods and applications therefore
WO2008019352A1 (en) 2006-08-04 2008-02-14 Nerites Corporation Biomimetic compounds and synthetic methods therefor
US8673286B2 (en) 2007-04-09 2014-03-18 Northwestern University DOPA-functionalized, branched, poly(aklylene oxide) adhesives
US8383092B2 (en) * 2007-02-16 2013-02-26 Knc Ner Acquisition Sub, Inc. Bioadhesive constructs
WO2009051967A1 (en) 2007-10-17 2009-04-23 Spire Corporation Manufacture of split tip catheters
US8292841B2 (en) 2007-10-26 2012-10-23 C. R. Bard, Inc. Solid-body catheter including lateral distal openings
US8066660B2 (en) 2007-10-26 2011-11-29 C. R. Bard, Inc. Split-tip catheter including lateral distal openings
US9579485B2 (en) 2007-11-01 2017-02-28 C. R. Bard, Inc. Catheter assembly including a multi-lumen configuration
CN101918067B (zh) 2007-11-01 2013-04-10 C·R·巴德股份有限公司 包括三个内腔末端的导管组件
BRPI0922344A2 (pt) * 2008-12-19 2017-10-24 3B Pharmaceuticals Gmbh inibidores de tfpi e métodos de uso
US20110130465A1 (en) * 2009-12-01 2011-06-02 Nerites Corporation Coatings for prevention of biofilms
WO2012064821A2 (en) 2010-11-09 2012-05-18 Knc Ner Acquisition Sub, Inc. Adhesive compounds and methods use for hernia repair
US9132025B2 (en) 2012-06-15 2015-09-15 Trivascular, Inc. Bifurcated endovascular prosthesis having tethered contralateral leg
USD748252S1 (en) 2013-02-08 2016-01-26 C. R. Bard, Inc. Multi-lumen catheter tip
WO2015134999A2 (en) 2014-03-07 2015-09-11 Case Western Reserve University Engineered tissue constructs
WO2016011091A1 (en) 2014-07-14 2016-01-21 C. R. Bard, Inc. Apparatuses, systems, and methods for inserting split tip catheters having enhanced stiffening and guiding features
WO2020041557A1 (en) * 2018-08-22 2020-02-27 Purdue Research Foundation Protein-based adhesive and its modification

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3759264A (en) * 1966-04-07 1973-09-18 Eastman Kodak Co Surgical method
JPS5550846B2 (es) * 1973-05-29 1980-12-20
US4808702A (en) * 1984-03-07 1989-02-28 Waite J Herbert Decapeptides produced from bioadhesive polyphenolic proteins
US4687740A (en) * 1984-03-07 1987-08-18 University Of Connecticut Research & Development Corp. Decapeptides produced from bioadhesive polyphenolic proteins
JPS6323670A (ja) * 1986-04-25 1988-01-30 バイオ−ポリマ−ズ　インコ−ポレ−テツド 接着・被覆組成物とその使用方法
DK163987A (da) * 1986-04-25 1987-10-26 Bio Polymers Inc Fremgangsmaade til fremstilling af dopa-holdige bioklaebende proteiner ud fra tyrosin-holdige proteiner
DE3773986D1 (de) * 1986-04-25 1991-11-28 Bio Polymers Inc Klebstoffderivate von bioadhaesiven polyphenolproteinen.
US5108923A (en) * 1986-04-25 1992-04-28 Collaborative Research, Inc. Bioadhesives for cell and tissue adhesion
JPH02501706A (ja) * 1986-11-24 1990-06-14 ジェネックス・コーポレーション 生物学的接着物質
WO1988007076A1 (en) * 1987-03-12 1988-09-22 Genex Corporation Production of bioadhesive precursor protein analogs by genetically-engineered organisms
NZ226170A (en) * 1987-09-18 1990-07-26 Ethicon Inc Stable freeze-dried pharmaceutical composition containing epidermal growth factor
US4904259A (en) * 1988-04-29 1990-02-27 Samuel Itay Compositions and methods for repair of cartilage and bone
US4908404A (en) * 1988-08-22 1990-03-13 Biopolymers, Inc. Synthetic amino acid-and/or peptide-containing graft copolymers
US5330911A (en) * 1989-09-28 1994-07-19 Board Of Regents, The University Of Texas System Surfaces having desirable cell adhesive effects
US5292362A (en) * 1990-07-27 1994-03-08 The Trustees Of Columbia University In The City Of New York Tissue bonding and sealing composition and method of using the same

Also Published As

Publication number Publication date
WO1992010567A1 (en) 1992-06-25
JPH06507304A (ja) 1994-08-25
DE69132315D1 (en) 2000-08-17
DE69132315T2 (de) 2000-11-30
EP0563172A1 (en) 1993-10-06
AU656354B2 (en) 1995-02-02
EP0563172B1 (en) 2000-07-12
ATE194650T1 (de) 2000-07-15
CA2098303A1 (en) 1992-06-15
US5374431A (en) 1994-12-20
CA2098303C (en) 2001-03-20
AU9132391A (en) 1992-07-08
US5197973A (en) 1993-03-30

Similar Documents

Publication Publication Date Title
ES2147727T3 (es) Polipeptido bioadhesivo sintetico.
DE3580525D1 (de) Mit schleifmittel beschichteter artikel fuer hochtemperaturanwendung.
FI801035A (fi) Foerfarande foer enzymatisk framstaellning av peptider
IS5087A (is) Stöðugar interferónlyfjablöndur á vökvaformi
MY104021A (en) Benzamide protease inhibitors.
DE3869192D1 (de) Zusatzmittel fuer zement.
ATE189136T1 (de) Beschichtetes verbindungsstück
DE3463671D1 (en) Method of improving the adhesion of adhesive layers applied from an aqueous dispersion to polyolefin surfaces
AU5791886A (en) Aziridine-treated articles
FI945704A0 (fi) Eksitatorisen aminohapporeseptorin antagonisteja
DE68910813D1 (de) Verfahren zur Stabilisierung von elektroaktiven Polymerelektroden.
ATE63750T1 (de) Peptid, dessen herstellung und benutzung.
BR0115807A (pt) Envidraçamento para uso automotivo
DE3670094D1 (de) Asphaltzementmasse mit hoher festigkeit zur strassenbeschichtung.
EP1500700A3 (en) Pectic acid lyase
ES8801570A1 (es) Un procedimiento para la preparacion de un hidralizado proteico.
ES2168282T3 (es) D-hidantoinasa recombinante, procedimiento para su preparacion y utilizacion.
TR23063A (tr) Termostabil lastik/metal birlestirme maddesi
ES2185630T3 (es) Nuevos polipeptidos y peptidos, acidos nucleicos que los codifican, y su utilizacion en el campo de la terapia de tumores, inflamacion o inmunologia.
DE59100712D1 (de) Anlage zum serienweisen Beschichten von Werkstücken mit leitfähigem Beschichtungsmaterial.
ES2165996T3 (es) Poliacrilamida con bajo peso molecular.
GB670107A (en) Improvements relating to means for marking lines on roads
IT8224380A0 (it) Amminoacidi fosfinilalcanoici utili come agenti ipotensivi.
IT8323020A0 (it) Immino ed amminoacidi acilossichetone sostituiti.
FI99136B (fi) Väliaikainen ruostumista estävä päällystyskoostumus

Legal Events

Date Code Title Description
FG2A Definitive protection

Ref document number: 563172

Country of ref document: ES