ES2146661T3 - Nuevos derivados de cefem. - Google Patents

Nuevos derivados de cefem.

Info

Publication number
ES2146661T3
ES2146661T3 ES94927055T ES94927055T ES2146661T3 ES 2146661 T3 ES2146661 T3 ES 2146661T3 ES 94927055 T ES94927055 T ES 94927055T ES 94927055 T ES94927055 T ES 94927055T ES 2146661 T3 ES2146661 T3 ES 2146661T3
Authority
ES
Spain
Prior art keywords
cefem
new derivatives
alkyl
compound
microbism
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES94927055T
Other languages
English (en)
Inventor
Kunio Atsumi
Eijiro Umemura
Yuko Kano
Sohjiro Shiokawa
Toshiaki Kudo
Masaki Tsushima
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Meiji Seika Kaisha Ltd
Original Assignee
Meiji Seika Kaisha Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Meiji Seika Kaisha Ltd filed Critical Meiji Seika Kaisha Ltd
Application granted granted Critical
Publication of ES2146661T3 publication Critical patent/ES2146661T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/22—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D277/28—Radicals substituted by nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D285/00—Heterocyclic compounds containing rings having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by groups C07D275/00 - C07D283/00
    • C07D285/01—Five-membered rings
    • C07D285/02—Thiadiazoles; Hydrogenated thiadiazoles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Cephalosporin Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

Abstract

UN COMPUESTO REPRESENTADO POR FORMULA (I) GENERAL, P. EJ., UN DERIVADO DE CEFENO QUE TIENE UN GRUPO IMIDAZO [5,1-B]TIAZOLIO-6-ILO (IN)SUSTITUIDO EN LA POSICION 3- DEL ANILLO, EN DONDE X REPRESENTA CH O N; R1 REPRESENTA H, ALQUILO, ALQUENILO, ETC.; Y R2, R3, R4 Y R5 REPRESENTA CADA UNO H, ALQUILO, CARBAMOILO, AMINO, ETC. ESTE COMPUESTO TIENE UNA EXCELENTE ACTIVIDAD ANTIBACTERIANA Y ES USADO COMO UN REMEDIO PARA VARIOS TIPOS DE MICROBISMO.
ES94927055T 1993-09-16 1994-09-16 Nuevos derivados de cefem. Expired - Lifetime ES2146661T3 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP23057393 1993-09-16
JP21190894 1994-08-12

Publications (1)

Publication Number Publication Date
ES2146661T3 true ES2146661T3 (es) 2000-08-16

Family

ID=26518899

Family Applications (1)

Application Number Title Priority Date Filing Date
ES94927055T Expired - Lifetime ES2146661T3 (es) 1993-09-16 1994-09-16 Nuevos derivados de cefem.

Country Status (11)

Country Link
US (1) US5663162A (es)
EP (1) EP0669336B1 (es)
JP (1) JP3152934B2 (es)
KR (1) KR0170046B1 (es)
CN (1) CN1046286C (es)
AT (1) ATE192927T1 (es)
CA (1) CA2149514C (es)
DE (1) DE69424524T2 (es)
ES (1) ES2146661T3 (es)
TW (1) TW385312B (es)
WO (1) WO1995007912A1 (es)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1996005205A1 (fr) * 1994-08-16 1996-02-22 Meiji Seika Kabushiki Kaisha Nouveau derive de cepheme
JP3527003B2 (ja) 1995-03-10 2004-05-17 明治製菓株式会社 新規イミダゾ［５，１−ｂ］チアゾール誘導体
DE69622801T2 (de) * 1995-03-10 2003-03-27 Meiji Seika K.K., Tokio/Tokyo Neue carbapenemderivate
JPH08319291A (ja) * 1995-05-25 1996-12-03 Meiji Seika Kaisha Ltd 新規セフェム誘導体
WO1998022469A1 (fr) * 1996-11-22 1998-05-28 Meiji Seika Kaisha, Ltd. Intermediaires de cepheme et leur procede de production
CA2274797A1 (en) 1996-12-09 1998-06-18 Takashi Ida Novel cephem derivatives
WO1998032760A1 (fr) 1997-01-28 1998-07-30 Meiji Seika Kaisha, Ltd. Nouveaux derives de carbapenem
WO2006077919A1 (ja) 2005-01-19 2006-07-27 Meiji Seika Kaisha, Ltd. イミダゾチアゾール誘導体およびその製造方法
CN109651400A (zh) * 2018-12-06 2019-04-19 淄博鑫泉医药技术服务有限公司 硫酸头孢匹罗的合成方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3374410D1 (en) * 1982-06-28 1987-12-17 Bristol Myers Co Cephalosporin derivatives, a process for the manufacture thereof and pharmaceutical compositions containing said derivatives
JPS59104593A (ja) * 1982-12-07 1984-06-16 株式会社東芝 沸騰水型原子炉の原子炉圧力容器内の水位計測装置
JPS61286388A (ja) * 1985-06-11 1986-12-16 Eisai Co Ltd ３−セフエム誘導体

Also Published As

Publication number Publication date
EP0669336A4 (en) 1996-04-10
US5663162A (en) 1997-09-02
DE69424524D1 (de) 2000-06-21
CA2149514C (en) 2000-10-31
WO1995007912A1 (fr) 1995-03-23
ATE192927T1 (de) 2000-06-15
CN1046286C (zh) 1999-11-10
CN1114507A (zh) 1996-01-03
EP0669336A1 (en) 1995-08-30
TW385312B (en) 2000-03-21
KR0170046B1 (ko) 1999-02-01
EP0669336B1 (en) 2000-05-17
JP3152934B2 (ja) 2001-04-03
DE69424524T2 (de) 2000-12-21
KR950704333A (ko) 1995-11-17

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