ES2145065T3 - Preparacion granular. - Google Patents

Preparacion granular.

Info

Publication number
ES2145065T3
ES2145065T3 ES93923650T ES93923650T ES2145065T3 ES 2145065 T3 ES2145065 T3 ES 2145065T3 ES 93923650 T ES93923650 T ES 93923650T ES 93923650 T ES93923650 T ES 93923650T ES 2145065 T3 ES2145065 T3 ES 2145065T3
Authority
ES
Spain
Prior art keywords
administration
pharmaceutical preparation
preparation
granular pharmaceutical
tube
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES93923650T
Other languages
English (en)
Inventor
Hiroaki Nakagami
Taketoshi Keshikawa
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Daiichi Pharmaceutical Co Ltd
Original Assignee
Daiichi Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Daiichi Pharmaceutical Co Ltd filed Critical Daiichi Pharmaceutical Co Ltd
Priority claimed from PCT/JP1993/001553 external-priority patent/WO1995011674A1/ja
Application granted granted Critical
Publication of ES2145065T3 publication Critical patent/ES2145065T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1617—Organic compounds, e.g. phospholipids, fats
    • A61K9/1623—Sugars or sugar alcohols, e.g. lactose; Derivatives thereof; Homeopathic globules
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1635—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates

Abstract

UNA PREPARACION GRANULOSA PRODUCIDA MEDIANTE LA GRANULACION FINA DE EBSELENO EN POLVO (2-FENIL-1,2-BENZISOSELONAZOL-3(2H)UNO) CON UN POLIMERO HIDROFILICO, Y UNA SUSPENSION ACUOSA DE LA PREPARACION. LA PREPARACION ES EXCELENTE PARA LA ADMINISTRACION A TRAVES DE UN TUBO ESTOMACAL, PUESTO QUE PUEDE SER DISPERSADA FACIL Y HOMOGENEAMENTE EN AGUA O EN UNA SOLUCION ACUOSA CUANDO SE ENCUENTRA SUSPENDIDA EN LA MISMA ANTES DEL USO, Y CONSERVA UNA BUEN GRADO DE SUSPENSION, FACILITANDO ASI LA PRODUCCION DE UNA SOLUCION FARMACOLOGICA QUE LA CONTENGA Y SU ADMINISTRACION A TRAVES DEL TUBO. TAMBIEN, LA PREPARACION GRANULAR Y LA SOLUCION FARMACOLOGICA QUE LA CONTIENE PUEDE ADMINISTRARSE SIN PERMANECER EN LE TUBO Y POR TANTO LA DOSIS PUEDE MANTENERSE EXACTA. ADEMAS, ESTA PREPARACION PUEDE PRODUCIRSE SIN RECURRIR A UN APARATO O PROCEDIMIENTO ESPECIALES, SIENDO ASI ADAPTABLE A LA PRODUCCION MASIVA.
ES93923650T 1993-10-27 1993-10-27 Preparacion granular. Expired - Lifetime ES2145065T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/JP1993/001553 WO1995011674A1 (fr) 1992-04-28 1993-10-27 Preparation granulaire

Publications (1)

Publication Number Publication Date
ES2145065T3 true ES2145065T3 (es) 2000-07-01

Family

ID=14070606

Family Applications (1)

Application Number Title Priority Date Filing Date
ES93923650T Expired - Lifetime ES2145065T3 (es) 1993-10-27 1993-10-27 Preparacion granular.

Country Status (6)

Country Link
US (1) US6335036B1 (es)
AT (1) ATE190487T1 (es)
DE (1) DE69328128T2 (es)
DK (1) DK0729756T3 (es)
ES (1) ES2145065T3 (es)
RU (1) RU2143898C1 (es)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2368484A1 (en) 1999-03-31 2000-10-05 Daiichi Pharmaceutical Co., Ltd. Substrates for thioredoxin reductase
US20050191357A1 (en) * 2002-03-20 2005-09-01 Yoshiaki Kawashima Method of manufacturing chemical-containing composite particles
RU2491066C2 (ru) * 2008-02-28 2013-08-27 Сантен Фармасьютикал Ко., Лтд. Средство для профилактики и лечения глазного заболевания, сопровождающегося нарушением деятельности зрительного нерва
US10058542B1 (en) 2014-09-12 2018-08-28 Thioredoxin Systems Ab Composition comprising selenazol or thiazolone derivatives and silver and method of treatment therewith
WO2023240092A1 (en) * 2022-06-06 2023-12-14 Sound Pharmaceuticals Inc. Ebselen containing oral dosage forms

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3027073C2 (de) * 1980-07-17 1985-03-07 A. Nattermann & Cie GmbH, 5000 Köln Pharmazeutische Präparate, enthaltend 2-Phenyl-1,2-benzisoselenazol-3(2H)-on
DE3027075A1 (de) 1980-07-17 1982-02-18 A. Nattermann & Cie GmbH, 5000 Köln Benzisoselenazolone, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische praeparate
DK150008C (da) * 1981-11-20 1987-05-25 Benzon As Alfred Fremgangsmaade til fremstilling af et farmaceutisk oralt polydepotpraeparat
DE3226284A1 (de) 1982-07-14 1984-01-19 A. Nattermann & Cie GmbH, 5000 Köln Neue benzisoselenazolone, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische praeparate
JPS5942313A (ja) * 1982-09-01 1984-03-08 Teijin Ltd ポリビニルポリピロリドンを用いた製剤
DE3407511A1 (de) 1984-03-01 1985-09-05 A. Nattermann & Cie GmbH, 5000 Köln Benzisoselenazolthione, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische praeparate
DE3616923A1 (de) 1986-05-20 1987-11-26 Nattermann A & Cie Neue pharmazeutische verwendung von 2-phenyl-1,2-benzisoselenazol-3(2h)-on
DE3620674A1 (de) * 1986-06-20 1987-12-23 Nattermann A & Cie Salbe zur behandlung von hauterkrankungen
JPH0755905B2 (ja) 1986-07-17 1995-06-14 第一製薬株式会社 肝臓疾患治療剤
US4778814A (en) * 1987-03-18 1988-10-18 Ciba-Geigy Corporation Method of treating ocular allergy by topical application of a 2-substituted-1,2-benzisoselenazol-3(2H)-one
DE3720493A1 (de) * 1987-06-20 1989-01-26 Nattermann A & Cie Arzneizubereitungen mit mikronisierten ebselen-kristallen
JPS6413522A (en) 1987-07-08 1989-01-18 Ricoh Kk Liquid crystal display device
DE3821392A1 (de) 1988-06-24 1989-12-28 Nattermann A & Cie Neue pharmazeutische verwendung von 2-phenyl-1,2-benzisoselenazol-3(2h)-on (ebselen)
DE3827093A1 (de) * 1988-08-10 1990-02-15 Nattermann A & Cie Verfahren zur herstellung von hochreinem ebselen
US5288734A (en) * 1988-10-29 1994-02-22 A. Nattermann & Cie Gmbh Stable parenteral solution of 2-phenyl-1.2-benzisoselenazol-3(2H)-one and process for producing the same
US5385726A (en) * 1990-08-06 1995-01-31 Rhone-Poulenc Rorer Gmbh Use of 2-phenyl-1,2-benzisoselenazol-3-(2H)-one
DE4024885C2 (de) 1990-08-06 2002-07-18 Nattermann A & Cie Verwendung von 2-Phenyl-1,2-benzisoselenazol-3(2H)-on
EP0826370B1 (de) * 1996-08-27 2002-06-19 A. Nattermann & Cie. GmbH Pharmazeutische Zubereitung, die 2-Phenyl-1,2-Benzoisoelenazol-3(2H)-one enthält, für die Behandlung der Alzheimer-Krankheit

Also Published As

Publication number Publication date
US6335036B1 (en) 2002-01-01
DE69328128D1 (de) 2000-04-20
DK0729756T3 (da) 2000-06-05
RU2143898C1 (ru) 2000-01-10
ATE190487T1 (de) 2000-04-15
DE69328128T2 (de) 2000-08-24

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Effective date: 19951114

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