JPS6479111A - Sustained release preparation and production thereof - Google Patents
Sustained release preparation and production thereofInfo
- Publication number
- JPS6479111A JPS6479111A JP63110791A JP11079188A JPS6479111A JP S6479111 A JPS6479111 A JP S6479111A JP 63110791 A JP63110791 A JP 63110791A JP 11079188 A JP11079188 A JP 11079188A JP S6479111 A JPS6479111 A JP S6479111A
- Authority
- JP
- Japan
- Prior art keywords
- drug
- polymer
- water
- sustained release
- ion
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Abstract
PURPOSE:To obtain a sustained release microcapsule agent containing a drug having high concentration, not swelling by water absorption, by coating a drug- polymer composite material having a crosslinking degree of ion exchange polymer and a drug concentration prescribed in specific ranges with a coating film of water-permeable high polymer. CONSTITUTION:An ion exchange polymer having adsorbed >=80%, especially 85-100% drug based on theoretical ion absorption amount and 6-16%, preferably 8-14% crosslinking degree is coated with a coating film of a water- permeable high polymer (e.g., aminoalkyl methacrylate copolymer). The ion exchanger polymer has 5-1,000mum, especially 10-300mum average particle diameter and a basic drug having 7.5-10pKa or an acidic drug having 2-5pKa is preferable as the drug used. 0.2-10g of the preparation is suspended in 100ml purified water to prepare suspension for oral administration.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP11079188A JPH075458B2 (en) | 1987-06-02 | 1988-05-07 | Sustained release preparation and method for producing the same |
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP13878187 | 1987-06-02 | ||
JP62-138781 | 1987-06-02 | ||
JP11079188A JPH075458B2 (en) | 1987-06-02 | 1988-05-07 | Sustained release preparation and method for producing the same |
Publications (2)
Publication Number | Publication Date |
---|---|
JPS6479111A true JPS6479111A (en) | 1989-03-24 |
JPH075458B2 JPH075458B2 (en) | 1995-01-25 |
Family
ID=26450321
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP11079188A Expired - Fee Related JPH075458B2 (en) | 1987-06-02 | 1988-05-07 | Sustained release preparation and method for producing the same |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPH075458B2 (en) |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2006512327A (en) * | 2002-11-26 | 2006-04-13 | ホ−レンベック ギャリ− ア−ル | Aqueous sustained-release drug delivery system for highly water-soluble electrolyte drugs |
JP2011530491A (en) * | 2008-08-08 | 2011-12-22 | ビーエーエスエフ ソシエタス・ヨーロピア | Biopolymer-based continuous fiber layers containing active substances, their use, and methods for their production |
-
1988
- 1988-05-07 JP JP11079188A patent/JPH075458B2/en not_active Expired - Fee Related
Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2006512327A (en) * | 2002-11-26 | 2006-04-13 | ホ−レンベック ギャリ− ア−ル | Aqueous sustained-release drug delivery system for highly water-soluble electrolyte drugs |
JP4808405B2 (en) * | 2002-11-26 | 2011-11-02 | ホ−レンベック ギャリ− ア−ル | Aqueous sustained-release drug delivery system for highly water-soluble electrolyte drugs |
JP2011530491A (en) * | 2008-08-08 | 2011-12-22 | ビーエーエスエフ ソシエタス・ヨーロピア | Biopolymer-based continuous fiber layers containing active substances, their use, and methods for their production |
Also Published As
Publication number | Publication date |
---|---|
JPH075458B2 (en) | 1995-01-25 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
LAPS | Cancellation because of no payment of annual fees |