ES2139751T3 - Proteina inhibidora de melanomas. - Google Patents

Proteina inhibidora de melanomas.

Info

Publication number
ES2139751T3
ES2139751T3 ES94925364T ES94925364T ES2139751T3 ES 2139751 T3 ES2139751 T3 ES 2139751T3 ES 94925364 T ES94925364 T ES 94925364T ES 94925364 T ES94925364 T ES 94925364T ES 2139751 T3 ES2139751 T3 ES 2139751T3
Authority
ES
Spain
Prior art keywords
iib
iia
protein
htz
hybridise
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES94925364T
Other languages
English (en)
Inventor
Ulrich Bogdahn
Reinhard Buttner
Brigitte Kaluza
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Roche Diagnostics GmbH
Original Assignee
Roche Diagnostics GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Roche Diagnostics GmbH filed Critical Roche Diagnostics GmbH
Application granted granted Critical
Publication of ES2139751T3 publication Critical patent/ES2139751T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4702—Regulators; Modulating activity
    • C07K14/4703—Inhibitors; Suppressors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

Abstract

LA INVENCION SE REFIERE A UNA PROTEINA INHIBIDORA DE MELANOMA, PARA SECUENCIA DE ACIDO NUCLEICO QUE CODIFICA ESTA PROTEINA, PROCESO PARA LA OBTENCION DE ESTA PROTEINA ASI COMO SU UTILIZACION EN LA ELABORACION DE AGENTES TERAPEUTICOS.
ES94925364T 1993-07-20 1994-07-19 Proteina inhibidora de melanomas. Expired - Lifetime ES2139751T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE4324247 1993-07-20

Publications (1)

Publication Number Publication Date
ES2139751T3 true ES2139751T3 (es) 2000-02-16

Family

ID=6493222

Family Applications (1)

Application Number Title Priority Date Filing Date
ES94925364T Expired - Lifetime ES2139751T3 (es) 1993-07-20 1994-07-19 Proteina inhibidora de melanomas.

Country Status (14)

Country Link
US (1) US5770366A (es)
EP (2) EP0710248B1 (es)
JP (1) JP3435163B2 (es)
CN (1) CN1056617C (es)
AT (1) ATE185152T1 (es)
AU (1) AU7531294A (es)
CA (1) CA2167693C (es)
DE (2) DE4425481A1 (es)
DK (1) DK0710248T3 (es)
ES (1) ES2139751T3 (es)
GR (1) GR3032212T3 (es)
IL (2) IL110385A (es)
WO (1) WO1995003328A2 (es)
ZA (1) ZA945278B (es)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19653358A1 (de) * 1996-12-20 1998-06-25 Boehringer Mannheim Gmbh Immunoassay zum Nachweis von MIA
WO1998031799A2 (en) 1997-01-21 1998-07-23 Human Genome Sciences, Inc. Polynucleotides and polypeptides encoding receptors
US6492144B1 (en) * 1997-05-30 2002-12-10 Diagen Corporation Methods for detection of nucleic acid sequences in urine
USRE39920E1 (en) 1997-05-30 2007-11-13 Xenomics, Inc. Methods for detection of nucleic acid sequences in urine
EP0945507A1 (de) * 1998-03-27 1999-09-29 Boehringer Mannheim Gmbh Tumorspezifische Expressionskontrollregion und deren Verwendung
US20020103360A1 (en) * 1998-09-01 2002-08-01 Yang Pan Novel protein related to melanoma-inhibiting protein and uses thereof
US20030072767A1 (en) * 1998-09-30 2003-04-17 Alexander Gaiger Compositions and methods for WT1 specific immunotherapy
EP1025871A1 (en) * 1999-01-28 2000-08-09 F. Hoffmann-La Roche Ag Use of a melanoma inhibiting activity factor (MIA) for cartilage and bone repair
US6713293B1 (en) * 1999-02-08 2004-03-30 Friedrich Grummt Encapsulated cells containing an amplified expression vector as a drug delivery device
CA2377791A1 (en) * 1999-06-30 2001-01-11 Takeda Chemical Industries, Ltd. Novel polypeptide and dna thereof
AU2001232967A1 (en) * 2000-01-25 2001-08-07 Hyseq, Inc. Methods and materials relating to novel growth regulatory-like polypeptides and polynucleotides
EP1133994A1 (en) * 2000-03-11 2001-09-19 Biognostik Gesellschaft für biomolekulare Diagnostik mbH A method for reversing the immunosuppressive effects of the Melanoma Inhibitory Activity "MIA"
NZ520346A (en) * 2000-03-23 2004-07-30 Akzo Nobel Nv Use of MIA in immunotherapy
US6613534B2 (en) 2001-03-20 2003-09-02 Wake Forest University Health Sciences MAP-2 as a determinant of metastatic potential
US20100212037A1 (en) * 2002-10-16 2010-08-19 Anja Katrin Bosserhoff Mia-2 protein
RU2480769C2 (ru) * 2006-07-28 2013-04-27 Новартис Аг Применение белка с меланома-ингибирующей активностью (миа) в качестве раннего индикатора терапевтического ответа при меланоме
TR201802758T4 (tr) * 2007-08-22 2018-03-21 Trovagene Inc In vivo hücre ölümünün saptanmasına yönelik miRNA kullanmanın yöntemleri.
EP2563809B1 (en) 2010-04-27 2020-04-01 Scil Technology GmbH Stable aqueous mia/cd-rap formulations
MX2013001536A (es) * 2010-08-30 2013-03-18 Hoffmann La Roche Construccion de expresion procariotica.
ITRM20110134A1 (it) * 2011-03-22 2012-09-23 Matteo Bordignon Inibitori di mia (attività inibitoria melanoma) per identificare, prevenire e curare la vitiligine

Also Published As

Publication number Publication date
EP0947583A2 (de) 1999-10-06
CN1133049A (zh) 1996-10-09
CA2167693A1 (en) 1995-02-02
WO1995003328A3 (de) 1995-03-16
ATE185152T1 (de) 1999-10-15
DE4425481A1 (de) 1995-03-02
CA2167693C (en) 2007-01-30
CN1056617C (zh) 2000-09-20
DK0710248T3 (da) 2000-04-10
JPH09500531A (ja) 1997-01-21
GR3032212T3 (en) 2000-04-27
DE59408791D1 (de) 1999-11-04
EP0947583A3 (de) 2000-05-03
US5770366A (en) 1998-06-23
ZA945278B (en) 1996-01-19
IL154248A (en) 2008-08-07
EP0710248B1 (de) 1999-09-29
IL110385A (en) 2003-12-10
JP3435163B2 (ja) 2003-08-11
WO1995003328A2 (de) 1995-02-02
AU7531294A (en) 1995-02-20
IL110385A0 (en) 1994-10-21
IL154248A0 (en) 2003-09-17
EP0710248A1 (de) 1996-05-08

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