ES2133150T3 - Sistema de liposomas acuoso, asi como procedimiento para la preparacion de un sistema de liposomas de este tipo. - Google Patents

Sistema de liposomas acuoso, asi como procedimiento para la preparacion de un sistema de liposomas de este tipo.

Info

Publication number
ES2133150T3
ES2133150T3 ES94103244T ES94103244T ES2133150T3 ES 2133150 T3 ES2133150 T3 ES 2133150T3 ES 94103244 T ES94103244 T ES 94103244T ES 94103244 T ES94103244 T ES 94103244T ES 2133150 T3 ES2133150 T3 ES 2133150T3
Authority
ES
Spain
Prior art keywords
liposoma
phospholipid
bile acid
aqueous
procedure
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES94103244T
Other languages
English (en)
Inventor
Jorg-Christian Hager
Josef-Peter Dr Lohr
Manfred Dr Durr
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sanofi Aventis Deutschland GmbH
Original Assignee
Rhone Poulenc Rorer GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Rhone Poulenc Rorer GmbH filed Critical Rhone Poulenc Rorer GmbH
Application granted granted Critical
Publication of ES2133150T3 publication Critical patent/ES2133150T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
    • A61K8/14—Liposomes; Vesicles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Liposomes
    • A61K9/1271—Non-conventional liposomes, e.g. PEGylated liposomes, liposomes coated with polymers
    • A61K9/1272—Non-conventional liposomes, e.g. PEGylated liposomes, liposomes coated with polymers with substantial amounts of non-phosphatidyl, i.e. non-acylglycerophosphate, surfactants as bilayer-forming substances, e.g. cationic lipids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/20—Chemical, physico-chemical or functional or structural properties of the composition as a whole
    • A61K2800/26—Optical properties
    • A61K2800/262—Transparent; Translucent

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Molecular Biology (AREA)
  • Birds (AREA)
  • Dispersion Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Biophysics (AREA)
  • Dermatology (AREA)
  • Medicinal Preparation (AREA)
  • Manufacturing Of Micro-Capsules (AREA)
  • Cosmetics (AREA)
  • Saccharide Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

SE DESCRIBE UN SISTEMA DE LIPOSOMAS ACUOSO QUE CONTIENE EVENTUALMENTE JUNTO A UN DISOLVENTE ORGANICO, NO TOXICO, AL MENOS UN FOSFOLIPIDO ASI COMO AL MENOS UNA OTRA SUSTANCIA NO FOSFOLIPIDICA. LA SUSTANCIA NO FOSFOLIPIDICA SE TRATA DE UN ACIDO BILIAR, UNA SAL DE ACIDO BILIAR, UN DERIVADO DE ACIDO BILIAR Y/O UNA SAL DE UN DERIVADO DE ACIDO BILIAR. LA RELACION DE MASA DEL FOSFOLIPIDO A LA OTRA SUSTANCIA NO FOSFOLIPIDICA VARIA ENTRE 1 : 0,001 HASTA 1 : 0,1. SE PREVE UN PROCESO PARA LA ELABORACION DEL SISTEMA DE LIPOSOMAS, DONDE SE DISUELVE PRIMERO EL FOSFOLIPIDO CON LA OTRA SUSTANCIA AL MENOS NO FOSFOLIPIDICA EN UNA RELACION DE MASAS DESDE 1 : 0,001 HASTA 1 : 0,1 EN UN DISOLVENTE ORGANICO O SE DISPERSA, A CONTINUACION LA SOLUCION O LA DISPERSION SE REDUCE EN CANTIDAD Y A PARTIR DE AQUI SE AÑADE AGUA BAJO LA FORMACION DEL SISTEMA DE LIPOSOMAS.
ES94103244T 1993-03-15 1994-03-04 Sistema de liposomas acuoso, asi como procedimiento para la preparacion de un sistema de liposomas de este tipo. Expired - Lifetime ES2133150T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE4308121A DE4308121A1 (de) 1993-03-15 1993-03-15 Wäßriges Liposomensystem sowie Verfahren zur Herstellung eines derartigen Liposomensystems

Publications (1)

Publication Number Publication Date
ES2133150T3 true ES2133150T3 (es) 1999-09-01

Family

ID=6482793

Family Applications (1)

Application Number Title Priority Date Filing Date
ES94103244T Expired - Lifetime ES2133150T3 (es) 1993-03-15 1994-03-04 Sistema de liposomas acuoso, asi como procedimiento para la preparacion de un sistema de liposomas de este tipo.

Country Status (8)

Country Link
EP (1) EP0615746B1 (es)
JP (1) JPH06321772A (es)
AT (1) ATE181826T1 (es)
CA (1) CA2119057C (es)
DE (2) DE4308121A1 (es)
DK (1) DK0615746T3 (es)
ES (1) ES2133150T3 (es)
GR (1) GR3030726T3 (es)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2196978A1 (es) * 2001-10-26 2003-12-16 Univ Barcelona Autonoma Composicion farmaceutica.

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19522694A1 (de) * 1995-06-22 1997-01-02 Vinas Jose Maria De Moragas Teerhaltige Zusammensetzung und diese enthaltende pharmazeutische und kosmetische Zubereitung
DE10349979B4 (de) * 2003-10-24 2006-05-18 Sanofi-Aventis Deutschland Gmbh Medikamentöse gezielte lokale Lipolyse
CA2584537C (en) * 2004-10-19 2013-09-24 Hansjorg Eibl Formulations containing alkylphosphocholines using novel negative charge carriers
DE102007015701A1 (de) 2007-03-19 2008-09-25 Maria Clementine Martin Klosterfrau Vertriebsgesellschaft Mbh Neue pharmazeutische Zusammensetzungen für die Lipolyse und Verfahren zu deren Herstellung
DE102010028365A1 (de) 2010-04-29 2011-11-03 Lichtblick Gmbh Verwendung einer Phospholipid enthaltenden Zusammensetzung zur Entfernung von subkutanen Fettansammlungen
WO2013180253A1 (ja) * 2012-05-31 2013-12-05 テルモ株式会社 ｐＨ感受性担体およびその製造方法、並びに該担体を含むｐＨ感受性医薬、ｐＨ感受性医薬組成物およびこれを用いた培養方法
RU2725622C1 (ru) * 2019-10-30 2020-07-03 Открытое акционерное общество "Фармстандарт-Лексредства" (ОАО "Фармстандарт-Лексредства") Фармацевтическая композиция для лечения и/или профилактики заболеваний печени

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE464743B (sv) * 1989-06-21 1991-06-10 Ytkemiska Inst Foerfarande foer framstaellning av laekemedelspartiklar
JP3765579B2 (ja) * 1990-08-24 2006-04-12 イーデーエーアー アーゲー 作用物質投与用超微小滴状調剤
AU4327193A (en) * 1992-07-08 1994-01-31 Dianorm-Gerate G. Maierhofer Liposomes, method of preparing them and their use in the preparation of drugs

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2196978A1 (es) * 2001-10-26 2003-12-16 Univ Barcelona Autonoma Composicion farmaceutica.

Also Published As

Publication number Publication date
DE59408450D1 (de) 1999-08-12
GR3030726T3 (en) 1999-11-30
DE4308121A1 (de) 1994-09-22
JPH06321772A (ja) 1994-11-22
EP0615746B1 (de) 1999-07-07
CA2119057C (en) 2004-01-20
ATE181826T1 (de) 1999-07-15
EP0615746A1 (de) 1994-09-21
CA2119057A1 (en) 1994-09-16
DK0615746T3 (da) 1999-11-22

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