ES2132437T3 - Procedimiento para la obtencion de derivados substituidos del acido fenilacetico y productos intermedios. - Google Patents
Procedimiento para la obtencion de derivados substituidos del acido fenilacetico y productos intermedios.Info
- Publication number
- ES2132437T3 ES2132437T3 ES95100486T ES95100486T ES2132437T3 ES 2132437 T3 ES2132437 T3 ES 2132437T3 ES 95100486 T ES95100486 T ES 95100486T ES 95100486 T ES95100486 T ES 95100486T ES 2132437 T3 ES2132437 T3 ES 2132437T3
- Authority
- ES
- Spain
- Prior art keywords
- opt
- substd
- formula
- alkyl
- acid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C309/00—Sulfonic acids; Halides, esters, or anhydrides thereof
- C07C309/63—Esters of sulfonic acids
- C07C309/72—Esters of sulfonic acids having sulfur atoms of esterified sulfo groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
- C07C309/73—Esters of sulfonic acids having sulfur atoms of esterified sulfo groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton to carbon atoms of non-condensed six-membered aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
- C07C51/02—Preparation of carboxylic acids or their salts, halides or anhydrides from salts of carboxylic acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B37/00—Reactions without formation or introduction of functional groups containing hetero atoms, involving either the formation of a carbon-to-carbon bond between two carbon atoms not directly linked already or the disconnection of two directly linked carbon atoms
- C07B37/04—Substitution
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C253/00—Preparation of carboxylic acid nitriles
- C07C253/30—Preparation of carboxylic acid nitriles by reactions not involving the formation of cyano groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C255/00—Carboxylic acid nitriles
- C07C255/01—Carboxylic acid nitriles having cyano groups bound to acyclic carbon atoms
- C07C255/32—Carboxylic acid nitriles having cyano groups bound to acyclic carbon atoms having cyano groups bound to acyclic carbon atoms of a carbon skeleton containing at least one six-membered aromatic ring
- C07C255/33—Carboxylic acid nitriles having cyano groups bound to acyclic carbon atoms having cyano groups bound to acyclic carbon atoms of a carbon skeleton containing at least one six-membered aromatic ring with cyano groups linked to the six-membered aromatic ring, or to the condensed ring system containing that ring, by saturated carbon chains
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C309/00—Sulfonic acids; Halides, esters, or anhydrides thereof
- C07C309/63—Esters of sulfonic acids
- C07C309/64—Esters of sulfonic acids having sulfur atoms of esterified sulfo groups bound to acyclic carbon atoms
- C07C309/65—Esters of sulfonic acids having sulfur atoms of esterified sulfo groups bound to acyclic carbon atoms of a saturated carbon skeleton
- C07C309/66—Methanesulfonates
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
- C07C51/09—Preparation of carboxylic acids or their salts, halides or anhydrides from carboxylic acid esters or lactones
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
- C07C51/347—Preparation of carboxylic acids or their salts, halides or anhydrides by reactions not involving formation of carboxyl groups
- C07C51/353—Preparation of carboxylic acids or their salts, halides or anhydrides by reactions not involving formation of carboxyl groups by isomerisation; by change of size of the carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C67/00—Preparation of carboxylic acid esters
- C07C67/30—Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group
- C07C67/333—Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group by isomerisation; by change of size of the carbon skeleton
- C07C67/343—Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
- C07C69/612—Esters of carboxylic acids having a carboxyl group bound to an acyclic carbon atom and having a six-membered aromatic ring in the acid moiety
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
PROCESO PARA LA ELABORACION DE DERIVADOS ACIDO ACETICO FENIL DE LA FORMULA (I) EN DONDE AR ES FENIL EVENTUALMENTE SUSTITUIDO DESDE 1 HASTA 5 VECES, DE FORMA IGUAL O DIFERENTE, DONDE COMO SUSTITUYENTES CONOCIDOS SON: HALOGENO, ALQUIL, ALCOXI, HALOGENALQUIL, HALOGENALCOXI, ALQUILCARBONILAMINO, ARIL EVENTUALMENTE SUSTITUIDO Y ARILOXI EVENTUALMENTE SUSTITUIDO Y R1 SIGNIFICA CIANO, AMINO CARBONIL, ALQUILAMINO CARBONIL, DIALQUILAMINO CARBONIL O UN GRUPO - COOR2, DONDE R2 ES HIDROGENO, ALQUIL EVENTUALMENTE SUSTITUIDO, ALQUENIL, ARIL EVENTUALMENTE SUSTITUIDO POR HALOGENALQUIL O ARALQUIL, CARACTERIZANDOSE, PORQUE SE TRANSFORMA UN DERIVADO ACIDO ACETICO HIDROXI SULFONILOXI ACTIVADO DE LA FORMULA (II) EN DONDE R1 TIENE EL SIGNIFICADO ANTES DADO Y R3 SIGNIFICA HALOGENO, ALQUIL, HALOGENALQUIL O ARIL SUSTITUIDO EVENTUALMENTE DE FORMA RESPECTIVA O BENCIL, CON AROMATICOS DE LA FORMULA (III) EN DONDE AR TIENE EL SIGNIFICADO ANTES DADO, EVENTUALMENTE EN PRESENCIA DE UN MEDIO DE DILUCION Y EN PRESENCIA DE UNACIDO Y A CONTINUACION SE HIDROLIZA EVENTUALMENTE. LOS PRODUCTOS INTERMEDIOS PARCIALMENTE NUEVOS DE LA FORMULA (II) SE OBTIENEN A PARTIR DE DERIVADOS ACETICO HIDROXI MEDIANTE TRANSFORMACION DE HALOGENUROS SULFONIL O ANHIDRIDOS DE ACIDO SULFONICO. LOS DERIVADOS DE ACIDO ACETICO FENIL DE LA FORMULA (I) SON COMPUESTOS DE PARTIDA IMPORTANTES PARA LA ELABORACION DE MEDIOS DE LUCHA CONTRA PARASITOS.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE4402403A DE4402403A1 (de) | 1994-01-27 | 1994-01-27 | Verfahren zur Herstellung von substituierten Phenylessigsäurederivaten und neue Zwischenprodukte |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2132437T3 true ES2132437T3 (es) | 1999-08-16 |
Family
ID=6508830
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES95100486T Expired - Lifetime ES2132437T3 (es) | 1994-01-27 | 1995-01-16 | Procedimiento para la obtencion de derivados substituidos del acido fenilacetico y productos intermedios. |
Country Status (12)
Country | Link |
---|---|
US (1) | US5698735A (es) |
EP (1) | EP0665212B1 (es) |
JP (1) | JPH07223995A (es) |
KR (1) | KR100353536B1 (es) |
CN (1) | CN1059434C (es) |
AT (1) | ATE181054T1 (es) |
BR (1) | BR9500339A (es) |
DE (2) | DE4402403A1 (es) |
DK (1) | DK0665212T3 (es) |
ES (1) | ES2132437T3 (es) |
HU (1) | HU216093B (es) |
IL (1) | IL112422A (es) |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
KR100457949B1 (ko) * | 2001-09-24 | 2004-11-18 | 주식회사 태평양 | 3,4,5-트리메톡시 페닐아세트산, 3,4,5-트리메톡시 신남산또는 3,4,5-트리메톡시 히드로 신남산의 에스테르화합물 및 이를 함유하는 미백 화장료조성물 |
CN103387490B (zh) | 2012-05-09 | 2015-08-26 | 中国科学院兰州化学物理研究所 | 一种甲苯羰化合成苯乙酸的方法 |
CN112079764B (zh) * | 2020-10-12 | 2023-08-01 | 山东汇海医药化工有限公司 | 一种舒尼替尼中间体5-氟吲哚-2-酮的合成方法 |
CN115819215A (zh) * | 2022-11-08 | 2023-03-21 | 广东省科学院化工研究所 | 一种路易斯酸催化合成羧酸衍生物的方法 |
Family Cites Families (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
BE633761A (es) * | ||||
GB971700A (en) * | 1961-02-02 | 1964-09-30 | Boots Pure Drug Co Ltd | Anti-Inflammatory Agents |
FR1374655A (fr) * | 1963-10-31 | 1964-10-09 | Westinghouse Electric Corp | Appareil de répartition de charge à réactance pour machine d'ynamoélectrique à redresseurs rotatifs |
FR1374665A (fr) * | 1963-11-04 | 1964-10-09 | Universal Oil Prod Co | Nouveaux composés phénylacétiques polyalcoyl-substitués et leur procédé de préparation |
JPS5312837A (en) * | 1976-07-23 | 1978-02-04 | Mitsui Toatsu Chem Inc | Preparation of alpha-phenylpropionic acid derivatives |
JPS53149945A (en) * | 1977-06-01 | 1978-12-27 | Mitsui Toatsu Chem Inc | Preparation of alpha-phenylpropionic acid derivatives |
DE3404336A1 (de) * | 1984-02-08 | 1985-08-08 | Basf Ag, 6700 Ludwigshafen | Verfahren zur herstellung von estern optisch aktiver 2-arylalkansaeuren |
JPS6296479A (ja) * | 1985-10-23 | 1987-05-02 | Shionogi & Co Ltd | ポリフルオロアルキルイソオキサゾリルアミン類 |
JPS62126159A (ja) * | 1985-11-26 | 1987-06-08 | Kyowa Hakko Kogyo Co Ltd | α−芳香族基置換アルカンニトリル類の製法 |
JPS62156159A (ja) * | 1985-12-28 | 1987-07-11 | Kurabe:Kk | 導電性樹脂組成物 |
GB8722838D0 (en) * | 1987-09-29 | 1987-11-04 | Shell Int Research | Oximino ether compounds |
ES2063108T3 (es) * | 1989-01-07 | 1995-01-01 | Bayer Ag | Derivados de 3-aril-pirrolidin-2,4-diona. |
GB8917222D0 (en) * | 1989-07-27 | 1989-09-13 | Schering Agrochemicals Ltd | Herbicides |
-
1994
- 1994-01-27 DE DE4402403A patent/DE4402403A1/de not_active Withdrawn
-
1995
- 1995-01-16 EP EP95100486A patent/EP0665212B1/de not_active Expired - Lifetime
- 1995-01-16 ES ES95100486T patent/ES2132437T3/es not_active Expired - Lifetime
- 1995-01-16 AT AT95100486T patent/ATE181054T1/de not_active IP Right Cessation
- 1995-01-16 DK DK95100486T patent/DK0665212T3/da active
- 1995-01-16 DE DE59506128T patent/DE59506128D1/de not_active Expired - Fee Related
- 1995-01-20 US US08/375,871 patent/US5698735A/en not_active Expired - Fee Related
- 1995-01-23 KR KR1019950001089A patent/KR100353536B1/ko not_active IP Right Cessation
- 1995-01-24 IL IL11242295A patent/IL112422A/en not_active IP Right Cessation
- 1995-01-24 JP JP7027232A patent/JPH07223995A/ja active Pending
- 1995-01-26 HU HUP9500238A patent/HU216093B/hu not_active IP Right Cessation
- 1995-01-26 BR BR9500339A patent/BR9500339A/pt not_active Application Discontinuation
- 1995-01-27 CN CN95101611A patent/CN1059434C/zh not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
IL112422A0 (en) | 1995-03-30 |
EP0665212A1 (de) | 1995-08-02 |
DK0665212T3 (da) | 1999-12-06 |
BR9500339A (pt) | 1995-10-17 |
HU216093B (hu) | 1999-04-28 |
JPH07223995A (ja) | 1995-08-22 |
DE59506128D1 (de) | 1999-07-15 |
US5698735A (en) | 1997-12-16 |
KR100353536B1 (ko) | 2003-03-06 |
KR950032052A (ko) | 1995-12-20 |
HU9500238D0 (en) | 1995-03-28 |
CN1109871A (zh) | 1995-10-11 |
HUT70693A (en) | 1995-10-30 |
CN1059434C (zh) | 2000-12-13 |
ATE181054T1 (de) | 1999-06-15 |
DE4402403A1 (de) | 1995-08-03 |
IL112422A (en) | 1998-10-30 |
EP0665212B1 (de) | 1999-06-09 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
DK0980242T3 (da) | Anvendelse af fumarsyrederivater til behandling af autoimmunsygdomme | |
DE50009060D1 (de) | Verfahren zur herstellung von arylalkylethern | |
HUT64512A (en) | Process for preparing acetic acid derivatives containing heteroatom with lipid level reducing activity and pharmaceutical compositions containing them | |
ITMI20050912A1 (it) | Processo di preparazione di acidi 3-a-ya(b)-diidrossi-6-a(b)-alchil-5b-colanici | |
ES2095059T3 (es) | Productos intermedios en un procedimiento para la purificacion de acido clavulanico. | |
AR247732A1 (es) | Procedimiento para obtener amidas de acido piridin-2, 4- y -2, 5-dicarboxilico | |
DE69903865D1 (de) | Wasserfreies Carbonylierungsverfahren zur Herstellung von Essigsäure | |
GB1072958A (en) | Diaminocarboxylic acid esters | |
ES2132437T3 (es) | Procedimiento para la obtencion de derivados substituidos del acido fenilacetico y productos intermedios. | |
DE50005769D1 (de) | Verfahren zur Herstellung von Di(meth)acrylsäureestern | |
DE60229087D1 (de) | VERFAHREN ZUR HERSTELLUNG VON 2-(4-CHLORBENZOYLAMINO-3-i2(1H)-CHINOLINON-4-YL PROPIONSÄURE | |
AR247214A1 (es) | Procedimiento para preparar fluorcetonas aromaticas sililadas que poseen propiedades inhibidoras de acetilcolinesterasa. | |
DE69937143D1 (de) | Verfahren zur reinigung eines cephalosporin-derivats | |
ES2118256T3 (es) | Derivados de acido propenoico utiles como fungicidas. | |
GB1365809A (en) | Production of halogenated organic phosphorus compounds | |
DE59508967D1 (de) | Verfahren zur Herstellung von halogenierten Alpha-Amino-Ketonen und Alpha-Amino-Alkoholen | |
PE20030929A1 (es) | Acidos 3-(imidazolil)-2-alcoxipropanoicos | |
ATE295368T1 (de) | Verfahren zur herstellung 3-amino-gallensaurer derivate | |
DE60008772D1 (de) | Verfahren zur herstellung von 7-amino-3-methoxymethyl-3-cephem-4-carbonsäure | |
DE60039299D1 (de) | Verfahren zur herstellung von optisch aktiven azetidin-2-carbonsäuren | |
DE69210309D1 (de) | Verfahren zur Herstellung von Alkyl-3-Chloroanthranilaten | |
DK0620857T3 (da) | Syntese af homochirale 2-hydroxysyrer | |
FI101539B1 (fi) | Fosfinaattiestereiden diastereoselektiivinen valmistus | |
NZ507202A (en) | Process for preparing beta keto esters and 1,3-dione compounds | |
TR26570A (tr) | HIDROJEL üRETIMINDE FOSFORIK ASIT DIGLISIDIL ESTER LERININ CAPRAZ BAGLAMA MADDESI OLARAK KULLANILMASI |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
FG2A | Definitive protection |
Ref document number: 665212 Country of ref document: ES |