ES2131073T3 - Metodo y composiciones para el tratamiento de la paralisis cerebral. - Google Patents
Metodo y composiciones para el tratamiento de la paralisis cerebral.Info
- Publication number
- ES2131073T3 ES2131073T3 ES92919570T ES92919570T ES2131073T3 ES 2131073 T3 ES2131073 T3 ES 2131073T3 ES 92919570 T ES92919570 T ES 92919570T ES 92919570 T ES92919570 T ES 92919570T ES 2131073 T3 ES2131073 T3 ES 2131073T3
- Authority
- ES
- Spain
- Prior art keywords
- compositions
- treatment
- brain paralysis
- botulinum toxin
- paralysis
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/43—Enzymes; Proenzymes; Derivatives thereof
- A61K38/46—Hydrolases (3)
- A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
- A61K38/4886—Metalloendopeptidases (3.4.24), e.g. collagenase
- A61K38/4893—Botulinum neurotoxin (3.4.24.69)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
- A61P21/02—Muscle relaxants, e.g. for tetanus or cramps
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
- C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
- C12N9/52—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from bacteria or Archaea
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
- C12Y304/24—Metalloendopeptidases (3.4.24)
- C12Y304/24069—Bontoxilysin (3.4.24.69), i.e. botulinum neurotoxin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/19—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Genetics & Genomics (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Physical Education & Sports Medicine (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Gastroenterology & Hepatology (AREA)
- Molecular Biology (AREA)
- Biotechnology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Microbiology (AREA)
- Immunology (AREA)
- Epidemiology (AREA)
- Toxicology (AREA)
- Neurosurgery (AREA)
- Pain & Pain Management (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Peptides Or Proteins (AREA)
Abstract
El uso de una neurotoxina presináptica que es una toxina botulínica, para la fabricación de un medicamento para la promoción del crecimiento muscular normal en un paciente joven antes de que el paciente haya completado su periodo de crecimiento y haya habido contracturas fijas, que padece de contracturas dinámicas debido a la parálisis cerebral.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB919120306A GB9120306D0 (en) | 1991-09-24 | 1991-09-24 | Method and compositions for the treatment of cerebral palsy |
GB9120306 | 1991-09-24 |
Publications (2)
Publication Number | Publication Date |
---|---|
ES2131073T3 true ES2131073T3 (es) | 1999-07-16 |
ES2131073T5 ES2131073T5 (es) | 2007-06-16 |
Family
ID=10701881
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES92919570T Expired - Lifetime ES2131073T5 (es) | 1991-09-24 | 1992-09-16 | Uso de una neurotoxina presinaptica para el tratamiento de la paralisis cerebral. |
Country Status (13)
Country | Link |
---|---|
US (7) | US6395277B1 (es) |
EP (1) | EP0605501B2 (es) |
JP (2) | JP3535872B2 (es) |
AT (1) | ATE178799T1 (es) |
AU (1) | AU666334B2 (es) |
CA (1) | CA2119562C (es) |
DE (1) | DE69228938T3 (es) |
DK (1) | DK0605501T5 (es) |
ES (1) | ES2131073T5 (es) |
GB (1) | GB9120306D0 (es) |
GR (1) | GR3030418T3 (es) |
NO (2) | NO312747B1 (es) |
WO (1) | WO1993005800A1 (es) |
Families Citing this family (117)
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GB9120306D0 (en) * | 1991-09-24 | 1991-11-06 | Graham Herbert K | Method and compositions for the treatment of cerebral palsy |
CA2138020C (en) * | 1992-06-23 | 1999-02-16 | Eric A. Johnson | Pharmaceutical composition containing botulinum b complex |
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US5437291A (en) * | 1993-08-26 | 1995-08-01 | Univ Johns Hopkins | Method for treating gastrointestinal muscle disorders and other smooth muscle dysfunction |
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US8187612B2 (en) * | 1993-12-28 | 2012-05-29 | Allergan, Inc. | Use of the neurotoxic component of a botulinum toxin for treating a spastic muscle |
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US5670484A (en) * | 1994-05-09 | 1997-09-23 | Binder; William J. | Method for treatment of skin lesions associated with cutaneous cell-proliferative disorders |
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1991
- 1991-09-24 GB GB919120306A patent/GB9120306D0/en active Pending
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1992
- 1992-09-16 ES ES92919570T patent/ES2131073T5/es not_active Expired - Lifetime
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- 1992-09-16 CA CA002119562A patent/CA2119562C/en not_active Expired - Lifetime
- 1992-09-16 AT AT92919570T patent/ATE178799T1/de active
- 1992-09-16 AU AU25664/92A patent/AU666334B2/en not_active Expired
- 1992-09-16 JP JP50589693A patent/JP3535872B2/ja not_active Expired - Lifetime
- 1992-09-16 DE DE69228938T patent/DE69228938T3/de not_active Expired - Lifetime
- 1992-09-16 WO PCT/GB1992/001697 patent/WO1993005800A1/en active IP Right Grant
- 1992-09-16 DK DK92919570T patent/DK0605501T5/da active
- 1992-09-16 US US08/211,352 patent/US6395277B1/en not_active Expired - Fee Related
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1994
- 1994-03-23 NO NO19941065A patent/NO312747B1/no not_active IP Right Cessation
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1999
- 1999-06-03 GR GR990401502T patent/GR3030418T3/el unknown
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2001
- 2001-07-06 US US09/900,380 patent/US6448231B2/en not_active Expired - Lifetime
- 2001-07-06 JP JP2001206187A patent/JP2002097154A/ja active Pending
- 2001-07-30 NO NO20013727A patent/NO324159B1/no not_active IP Right Cessation
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2002
- 2002-05-22 US US10/155,280 patent/US20020142010A1/en not_active Abandoned
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2004
- 2004-10-29 US US10/976,690 patent/US20050142150A1/en not_active Abandoned
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