DE69228938T2 - Methode und zusammensetzungen zur behandlung von zerebralparalyse - Google Patents

Methode und zusammensetzungen zur behandlung von zerebralparalyse

Info

Publication number
DE69228938T2
DE69228938T2 DE69228938T DE69228938T DE69228938T2 DE 69228938 T2 DE69228938 T2 DE 69228938T2 DE 69228938 T DE69228938 T DE 69228938T DE 69228938 T DE69228938 T DE 69228938T DE 69228938 T2 DE69228938 T2 DE 69228938T2
Authority
DE
Germany
Prior art keywords
compositions
treating cerebral
cerebral paralysis
paralysis
botulinum toxin
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69228938T
Other languages
English (en)
Other versions
DE69228938D1 (de
DE69228938T3 (de
Inventor
Herbert Graham
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Allergan Inc
Original Assignee
Allergan Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=10701881&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE69228938(T2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Allergan Inc filed Critical Allergan Inc
Publication of DE69228938D1 publication Critical patent/DE69228938D1/de
Publication of DE69228938T2 publication Critical patent/DE69228938T2/de
Application granted granted Critical
Publication of DE69228938T3 publication Critical patent/DE69228938T3/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46Hydrolases (3)
    • A61K38/48Hydrolases (3) acting on peptide bonds (3.4)
    • A61K38/4886Metalloendopeptidases (3.4.24), e.g. collagenase
    • A61K38/4893Botulinum neurotoxin (3.4.24.69)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00Drugs for disorders of the muscular or neuromuscular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00Drugs for disorders of the muscular or neuromuscular system
    • A61P21/02Muscle relaxants, e.g. for tetanus or cramps
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14Hydrolases (3)
    • C12N9/48Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/52Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from bacteria or Archaea
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y304/00Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
    • C12Y304/24Metalloendopeptidases (3.4.24)
    • C12Y304/24069Bontoxilysin (3.4.24.69), i.e. botulinum neurotoxin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/19Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Neurology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Biomedical Technology (AREA)
  • Toxicology (AREA)
  • Epidemiology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Microbiology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Pain & Pain Management (AREA)
  • Neurosurgery (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Peptides Or Proteins (AREA)
DE69228938T 1991-09-24 1992-09-16 Verwendung von präsynaptischen Neurotoxin zur Behandlung von Zerebralparalyse Expired - Lifetime DE69228938T3 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB919120306A GB9120306D0 (en) 1991-09-24 1991-09-24 Method and compositions for the treatment of cerebral palsy
GB9120306 1991-09-24
PCT/GB1992/001697 WO1993005800A1 (en) 1991-09-24 1992-09-16 Method and compositions for the treatment of cerebral palsy

Publications (3)

Publication Number Publication Date
DE69228938D1 DE69228938D1 (de) 1999-05-20
DE69228938T2 true DE69228938T2 (de) 1999-09-23
DE69228938T3 DE69228938T3 (de) 2008-01-03

Family

ID=10701881

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69228938T Expired - Lifetime DE69228938T3 (de) 1991-09-24 1992-09-16 Verwendung von präsynaptischen Neurotoxin zur Behandlung von Zerebralparalyse

Country Status (13)

Country Link
US (7) US6395277B1 (de)
EP (1) EP0605501B2 (de)
JP (2) JP3535872B2 (de)
AT (1) ATE178799T1 (de)
AU (1) AU666334B2 (de)
CA (1) CA2119562C (de)
DE (1) DE69228938T3 (de)
DK (1) DK0605501T5 (de)
ES (1) ES2131073T5 (de)
GB (1) GB9120306D0 (de)
GR (1) GR3030418T3 (de)
NO (2) NO312747B1 (de)
WO (1) WO1993005800A1 (de)

Families Citing this family (117)

* Cited by examiner, † Cited by third party
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NO20013727L (no) 1994-03-23
ATE178799T1 (de) 1999-04-15
CA2119562C (en) 2005-02-15
NO324159B1 (no) 2007-09-03
JP2002097154A (ja) 2002-04-02
NO941065D0 (no) 1994-03-23
DE69228938D1 (de) 1999-05-20
DK0605501T3 (da) 1999-10-25
CA2119562A1 (en) 1993-04-01
US6448231B2 (en) 2002-09-10
NO20013727D0 (no) 2001-07-30
US20050142150A1 (en) 2005-06-30
EP0605501B1 (de) 1999-04-14
NO941065L (no) 1994-03-23
DK0605501T5 (da) 2007-02-26
GR3030418T3 (en) 1999-09-30
EP0605501B2 (de) 2006-11-29
AU2566492A (en) 1993-04-27
US7378389B2 (en) 2008-05-27
ES2131073T5 (es) 2007-06-16
AU666334B2 (en) 1996-02-08
WO1993005800A1 (en) 1993-04-01
US20020142010A1 (en) 2002-10-03
JP3535872B2 (ja) 2004-06-07
NO312747B1 (no) 2002-07-01
US20050112146A1 (en) 2005-05-26
US20070224221A1 (en) 2007-09-27
DE69228938T3 (de) 2008-01-03
EP0605501A1 (de) 1994-07-13
GB9120306D0 (en) 1991-11-06
ES2131073T3 (es) 1999-07-16
US20080206224A1 (en) 2008-08-28
JPH06510779A (ja) 1994-12-01
US20010046962A1 (en) 2001-11-29

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