ES2123741T3 - Derivados de bencimidazol, su preparacion y uso. - Google Patents

Derivados de bencimidazol, su preparacion y uso.

Info

Publication number
ES2123741T3
ES2123741T3 ES94610013T ES94610013T ES2123741T3 ES 2123741 T3 ES2123741 T3 ES 2123741T3 ES 94610013 T ES94610013 T ES 94610013T ES 94610013 T ES94610013 T ES 94610013T ES 2123741 T3 ES2123741 T3 ES 2123741T3
Authority
ES
Spain
Prior art keywords
bencimidazole
derivatives
preparation
hydrogen
human
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES94610013T
Other languages
English (en)
Inventor
Soren-Peter Olesen
Leif Helth Jensen
Peter Moldt
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
NTG Nordic Transport Group AS
Original Assignee
Neurosearch AS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Neurosearch AS filed Critical Neurosearch AS
Application granted granted Critical
Publication of ES2123741T3 publication Critical patent/ES2123741T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
    • C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
    • C07D235/24—Benzimidazoles; Hydrogenated benzimidazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
    • C07D235/28—Sulfur atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/12—Antidiarrhoeals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/06—Anti-spasmodics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/10—Drugs for disorders of the urinary system of the bladder
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
    • C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
    • C07D235/24—Benzimidazoles; Hydrogenated benzimidazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
    • C07D235/26—Oxygen atoms

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Urology & Nephrology (AREA)
  • Pulmonology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Vascular Medicine (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

Abstract

SE PRESENTA UN COMPUESTO QUE TIENE LA FORMULA SIGUIENTE, EN LA QUE X ES O, S; R4, R5, R6 Y R7 SON INDEPENDIENTEMENTE HIDROGENO, HALOGENO O CF3; R1 ES HIDROGENO O NO2; Y ADEMAS SE PRESENTA UN METODO PARA TRATAR UNA ENFERMEDAD DE UN CUERPO DE UN ANIMAL VIVO, INCLUYENDO LOS HUMANOS, QUE ES SENSIBLE A LA ABERTURA DE LOS CANALES DE POTASIO, QUE COMPRENDE LA ADMINISTRACION AL CUERPO DEL ANIMAL VIVO, INCLUYENDO LOS HUMANOS, DE UNA CANTIDAD EFECTIVA DE UN COMPUESTO COMO EL DESCRITO.
ES94610013T 1993-03-15 1994-03-11 Derivados de bencimidazol, su preparacion y uso. Expired - Lifetime ES2123741T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DK93288A DK28893D0 (da) 1993-03-15 1993-03-15 Benzimidazole derivater, deres fremstilling og anvendelse

Publications (1)

Publication Number Publication Date
ES2123741T3 true ES2123741T3 (es) 1999-01-16

Family

ID=8091872

Family Applications (1)

Application Number Title Priority Date Filing Date
ES94610013T Expired - Lifetime ES2123741T3 (es) 1993-03-15 1994-03-11 Derivados de bencimidazol, su preparacion y uso.

Country Status (14)

Country Link
US (1) US5475015A (es)
EP (1) EP0617023B1 (es)
JP (1) JP3748901B2 (es)
KR (1) KR100300800B1 (es)
AT (1) ATE172453T1 (es)
AU (1) AU679023B2 (es)
CA (1) CA2118997C (es)
DE (1) DE69414017T2 (es)
DK (2) DK28893D0 (es)
ES (1) ES2123741T3 (es)
FI (1) FI941214A (es)
NO (1) NO304518B1 (es)
NZ (1) NZ260049A (es)
ZA (1) ZA941816B (es)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW467902B (en) * 1996-07-31 2001-12-11 Bristol Myers Squibb Co Diphenyl heterocycles as potassium channel modulators
EP1198456B1 (en) * 1999-08-03 2007-09-19 Abbott Laboratories Potassium channel openers
DE10209520A1 (de) * 2002-03-04 2003-09-25 4Sc Ag Neue Modulatoren von Kaliumkanälen
JP2005533814A (ja) * 2002-06-26 2005-11-10 ポセイドン・ファーマスーティカルス・アクティーゼルスカブ 新規ベンズイミダゾール−２−オン誘導体及びその使用方法
WO2005035498A1 (ja) * 2003-10-08 2005-04-21 Dainippon Sumitomo Pharma Co., Ltd. 含窒素二環性化合物の摂食調節剤としての用途

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ239540A (en) * 1990-09-24 1993-11-25 Neurosearch As 1-phenyl benzimidazole derivatives and medicaments
US5200422A (en) * 1990-09-24 1993-04-06 Neurosearch A/S Benzimidazole derivatives, their preparation and use

Also Published As

Publication number Publication date
KR100300800B1 (ko) 2001-11-22
DK0617023T3 (da) 1999-06-28
AU5649294A (en) 1994-09-22
CA2118997C (en) 2002-05-28
JPH06321910A (ja) 1994-11-22
DK28893D0 (da) 1993-03-15
NO940908D0 (no) 1994-03-14
US5475015A (en) 1995-12-12
JP3748901B2 (ja) 2006-02-22
NO304518B1 (no) 1999-01-04
FI941214A0 (fi) 1994-03-15
EP0617023A1 (en) 1994-09-28
NO940908L (no) 1994-09-16
ATE172453T1 (de) 1998-11-15
CA2118997A1 (en) 1994-09-16
ZA941816B (en) 1995-10-13
DE69414017T2 (de) 1999-04-08
DE69414017D1 (de) 1998-11-26
FI941214A (fi) 1994-09-16
NZ260049A (en) 1996-03-26
KR940021534A (ko) 1994-10-19
EP0617023B1 (en) 1998-10-21
AU679023B2 (en) 1997-06-19

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