HUP0200152A2 - KQT1 csatornák gátlóinak alkalmazása parazita férgek és ektoparaziták által okozott betegségek kezelésére alkalmas gyógyszerkészítmények előállítására - Google Patents

KQT1 csatornák gátlóinak alkalmazása parazita férgek és ektoparaziták által okozott betegségek kezelésére alkalmas gyógyszerkészítmények előállítására

Info

Publication number
HUP0200152A2
HUP0200152A2 HU0200152A HUP0200152A HUP0200152A2 HU P0200152 A2 HUP0200152 A2 HU P0200152A2 HU 0200152 A HU0200152 A HU 0200152A HU P0200152 A HUP0200152 A HU P0200152A HU P0200152 A2 HUP0200152 A2 HU P0200152A2
Authority
HU
Hungary
Prior art keywords
ectoparasites
inhibitors
kqt1
medicament
utilization
Prior art date
Application number
HU0200152A
Other languages
English (en)
Inventor
Uwe Gerlach
Joachim Hofmann
Hans Jochen Lang
Aguan Wei
Original Assignee
Aventis Pharma Deutschland Gmbh.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aventis Pharma Deutschland Gmbh. filed Critical Aventis Pharma Deutschland Gmbh.
Publication of HUP0200152A2 publication Critical patent/HUP0200152A2/hu
Publication of HUP0200152A3 publication Critical patent/HUP0200152A3/hu

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline 
    • A61K31/353—3,4-Dihydrobenzopyrans, e.g. chroman, catechin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/4433—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a six-membered ring with oxygen as a ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/18—Sulfonamides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline 
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/10—Anthelmintics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/14—Ectoparasiticides, e.g. scabicides

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyrane Compounds (AREA)

Abstract

A KQT1 csatorna inhibitorok alkalmazása a parazita férgek ésektoparaziták irtásának új elvét jelenti. Ezért a parazita férgekbenés ektoparazitákban előforduló celluláris KQT1 csatornák gátlóialkalmasak olyan gyógyszerkészítmények előállítására, amelyek parazitaférgek és ektoparaziták által fertőzött emberek és gerinces állatokkezelésére alkalmasak. A KQT1 inhibitorok gyógyszerként alkalmazhatókönmagukban vagy más gyógyszer-hatóanyagokkal kombinálva. A KQT1csatorna inhibitorok ezenkívül új hatásmechanizmust mutatnaknövénykárosító rovarok, pókok, puhatestűek és fonalférgek ellen, ezértnövényvédő szerek előállítására alkalmasak. Ó
HU0200152A 1998-12-17 1999-12-07 Utilization of inhibitors of the kqt1 channel in order to produce a medicament for treating diseases which are caused by parasitic helminths and ectoparasites HUP0200152A3 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19858253A DE19858253A1 (de) 1998-12-17 1998-12-17 Verwendung von Inhibitoren des KQt1-Kanals zur Herstellung eines Medikaments zur Behandlung von Krankheiten, die durch Helminthen und Ektoparasiten hervorgerufen werden

Publications (2)

Publication Number Publication Date
HUP0200152A2 true HUP0200152A2 (hu) 2002-05-29
HUP0200152A3 HUP0200152A3 (en) 2003-01-28

Family

ID=7891421

Family Applications (1)

Application Number Title Priority Date Filing Date
HU0200152A HUP0200152A3 (en) 1998-12-17 1999-12-07 Utilization of inhibitors of the kqt1 channel in order to produce a medicament for treating diseases which are caused by parasitic helminths and ectoparasites

Country Status (24)

Country Link
US (2) US6335363B1 (hu)
EP (1) EP1140042B1 (hu)
JP (1) JP2002532412A (hu)
KR (1) KR20010089574A (hu)
CN (1) CN1170528C (hu)
AR (1) AR021690A1 (hu)
AT (1) ATE390130T1 (hu)
AU (1) AU1559500A (hu)
BR (1) BR9916190A (hu)
CA (1) CA2355300A1 (hu)
CZ (1) CZ20012125A3 (hu)
DE (2) DE19858253A1 (hu)
HK (1) HK1041647B (hu)
HR (1) HRPK20010442B1 (hu)
HU (1) HUP0200152A3 (hu)
IL (1) IL143717A0 (hu)
NO (1) NO20012976L (hu)
NZ (1) NZ512408A (hu)
PL (1) PL349511A1 (hu)
RU (1) RU2238090C2 (hu)
SK (1) SK8562001A3 (hu)
TR (1) TR200101750T2 (hu)
WO (1) WO2000035429A1 (hu)
ZA (1) ZA200103620B (hu)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100956913B1 (ko) * 2003-12-19 2010-05-11 제넨테크, 인크. 치료제로서 유용한 일가 항체 단편
PT1773885E (pt) * 2004-08-05 2010-07-21 Genentech Inc Antagonistas anti-cmet humanizados
LT2883545T (lt) 2007-06-07 2018-10-25 Bayer Animal Health Gmbh Kova su ektoparazitais
US9968564B2 (en) * 2009-06-05 2018-05-15 Intercontinental Great Brands Llc Delivery of functional compounds
US20100307542A1 (en) * 2009-06-05 2010-12-09 Kraft Foods Global Brands Llc Method of Reducing Surface Oil on Encapsulated Material
US8859003B2 (en) * 2009-06-05 2014-10-14 Intercontinental Great Brands Llc Preparation of an enteric release system
US20100310726A1 (en) 2009-06-05 2010-12-09 Kraft Foods Global Brands Llc Novel Preparation of an Enteric Release System
KR20140045440A (ko) 2011-06-30 2014-04-16 제넨테크, 인크. 항-c-met 항체 제제
US8859005B2 (en) 2012-12-03 2014-10-14 Intercontinental Great Brands Llc Enteric delivery of functional ingredients suitable for hot comestible applications
MX2016012285A (es) 2014-03-24 2017-01-23 Genentech Inc Tratamiento de cáncer con antagonista de c-met y correlación de estos con la expresión de hgf.
EP2957557A1 (en) * 2014-06-17 2015-12-23 Novartis Tiergesundheit AG New compounds
CN109071504B (zh) 2016-02-05 2022-03-08 戴纳立制药公司 受体相互作用蛋白激酶1的抑制剂
DK3552017T3 (da) 2016-12-09 2022-05-16 Denali Therapeutics Inc Forbindelser, der er anvendelige som ripk1-inhibitorer
CN110770227B (zh) * 2017-06-30 2024-03-01 拜耳动物保健有限责任公司 新的氮杂喹啉衍生物

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ276577A (en) * 1993-11-29 1997-11-24 Merrell Pharma Inc 2-acyl-4-benzenesulphonyliminoquinoline and -chromene derivatives
US5559026A (en) * 1994-10-31 1996-09-24 American Cyanamid Company Genes encoding a novel family of potassium channels
DE19504379A1 (de) * 1995-02-10 1996-08-14 Hoechst Ag Substituierte Benzolsulfonylharnstoffe und -thioharnstoffe, Verfahren zu ihrer Herstellung und ihre Verwendung zur Herstellung pharmazeutischer Präparate sowie sie enthaltende pharmazeutische Präparate
HRP970255B1 (en) 1996-05-15 2003-10-31 Hoechst Ag Sulfonamido substituted chromane derivatives, method for their preparation, their use as medicaments or diagnostic agents as well as medicaments containing them
DE19706675A1 (de) * 1997-02-20 1998-08-27 Hoechst Ag Sulfonamid-substituierte Chromane, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament
DE19707656A1 (de) * 1997-02-26 1998-08-27 Hoechst Ag Sulfonamid-substituierte anellierte 7-Ring-Verbindungen, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltende pharmazeutische Zubereitungen
DE19742508A1 (de) 1997-09-26 1999-04-01 Hoechst Marion Roussel De Gmbh Sulfonamid-substituierte Chromane, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltende pharmazeutische Zubereitungen
DE19742509A1 (de) 1997-09-26 1999-04-01 Hoechst Marion Roussel De Gmbh Sulfonamid-substituierte Chromane, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltende pharmazeutische Zubereitungen
DE19748469A1 (de) * 1997-11-03 1999-05-06 Hoechst Marion Roussel De Gmbh Sulfonamid-substituierte Benzopyranderivate, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament sowie sie enthaltende pharmazeutische Zubereitungen

Also Published As

Publication number Publication date
CN1170528C (zh) 2004-10-13
NO20012976L (no) 2001-08-06
HK1041647A1 (en) 2002-07-19
BR9916190A (pt) 2001-09-11
DE59914712D1 (de) 2008-05-08
AU1559500A (en) 2000-07-03
NO20012976D0 (no) 2001-06-15
AR021690A1 (es) 2002-07-31
CZ20012125A3 (cs) 2001-09-12
WO2000035429A1 (de) 2000-06-22
TR200101750T2 (tr) 2002-01-21
EP1140042B1 (de) 2008-03-26
HRPK20010442B1 (en) 2003-10-31
ATE390130T1 (de) 2008-04-15
NZ512408A (en) 2003-10-31
SK8562001A3 (en) 2001-12-03
RU2238090C2 (ru) 2004-10-20
US20020055537A1 (en) 2002-05-09
DE19858253A1 (de) 2000-06-21
JP2002532412A (ja) 2002-10-02
EP1140042A1 (de) 2001-10-10
US6335363B1 (en) 2002-01-01
CA2355300A1 (en) 2000-06-22
HUP0200152A3 (en) 2003-01-28
CN1330540A (zh) 2002-01-09
KR20010089574A (ko) 2001-10-06
IL143717A0 (en) 2002-04-21
HK1041647B (zh) 2005-04-01
PL349511A1 (en) 2002-07-29
ZA200103620B (en) 2002-06-04
HRP20010442A2 (en) 2002-06-30

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Legal Events

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FD9A Lapse of provisional protection due to non-payment of fees