AR021690A1 - Empleo de inhibidores del canal de ktq1 para la preparacion de un medicamento para el tratamiento de enfermedades, que son provocadas por helmintos yectoparasitos. - Google Patents
Empleo de inhibidores del canal de ktq1 para la preparacion de un medicamento para el tratamiento de enfermedades, que son provocadas por helmintos yectoparasitos.Info
- Publication number
- AR021690A1 AR021690A1 ARP990106411A ARP990106411A AR021690A1 AR 021690 A1 AR021690 A1 AR 021690A1 AR P990106411 A ARP990106411 A AR P990106411A AR P990106411 A ARP990106411 A AR P990106411A AR 021690 A1 AR021690 A1 AR 021690A1
- Authority
- AR
- Argentina
- Prior art keywords
- ktq1
- preparation
- treatment
- channel inhibitors
- yectoparasites
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/4433—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a six-membered ring with oxygen as a ring hetero atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/18—Sulfonamides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
- A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
- A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline
- A61K31/353—3,4-Dihydrobenzopyrans, e.g. chroman, catechin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/10—Anthelmintics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/14—Ectoparasiticides, e.g. scabicides
Landscapes
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pyrane Compounds (AREA)
Abstract
Los inhibidores del canal de KTQ1 representan un nuevo principio letal para helmintos y ectoparásitos. Por lo tanto se emplean bloqueadores delcanal de KTQ1 celular, que se encuentra en helmintos y ectoparásitos, para la preparacion de un medicamentopara el tratamiento de animales vertebradosy seres humanos que son atacados por helmintos o ectoparásitos. Estos bloqueadores del canal de KTQ1 se emplean como medicamentos solos o en combinacioncon otros medicamentos y medidas terapéuticas. Los inhibidores del canal de KTQ1 representan asimismo un mecanismo eficaz para parásitos deplantas como insectos, arácnidos, moluscos y nematodos y se emplean consecuentemente para la preparacion de un agente fitoprotector.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE19858253A DE19858253A1 (de) | 1998-12-17 | 1998-12-17 | Verwendung von Inhibitoren des KQt1-Kanals zur Herstellung eines Medikaments zur Behandlung von Krankheiten, die durch Helminthen und Ektoparasiten hervorgerufen werden |
Publications (1)
Publication Number | Publication Date |
---|---|
AR021690A1 true AR021690A1 (es) | 2002-07-31 |
Family
ID=7891421
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ARP990106411A AR021690A1 (es) | 1998-12-17 | 1999-12-15 | Empleo de inhibidores del canal de ktq1 para la preparacion de un medicamento para el tratamiento de enfermedades, que son provocadas por helmintos yectoparasitos. |
Country Status (24)
Country | Link |
---|---|
US (2) | US6335363B1 (es) |
EP (1) | EP1140042B1 (es) |
JP (1) | JP2002532412A (es) |
KR (1) | KR20010089574A (es) |
CN (1) | CN1170528C (es) |
AR (1) | AR021690A1 (es) |
AT (1) | ATE390130T1 (es) |
AU (1) | AU1559500A (es) |
BR (1) | BR9916190A (es) |
CA (1) | CA2355300A1 (es) |
CZ (1) | CZ20012125A3 (es) |
DE (2) | DE19858253A1 (es) |
HK (1) | HK1041647B (es) |
HR (1) | HRPK20010442B1 (es) |
HU (1) | HUP0200152A3 (es) |
IL (1) | IL143717A0 (es) |
NO (1) | NO20012976L (es) |
NZ (1) | NZ512408A (es) |
PL (1) | PL349511A1 (es) |
RU (1) | RU2238090C2 (es) |
SK (1) | SK8562001A3 (es) |
TR (1) | TR200101750T2 (es) |
WO (1) | WO2000035429A1 (es) |
ZA (1) | ZA200103620B (es) |
Families Citing this family (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ZA200604864B (en) * | 2003-12-19 | 2007-10-31 | Genentech Inc | Monovalent antibody fragments useful as therapeutics |
RS51326B (sr) * | 2004-08-05 | 2010-12-31 | Genentech Inc. | Humanizovani anti-cmet antagonisti |
DK2883545T3 (en) | 2007-06-07 | 2018-11-05 | Bayer Animal Health Gmbh | Control of ectoparasites |
US20100310726A1 (en) | 2009-06-05 | 2010-12-09 | Kraft Foods Global Brands Llc | Novel Preparation of an Enteric Release System |
US9968564B2 (en) | 2009-06-05 | 2018-05-15 | Intercontinental Great Brands Llc | Delivery of functional compounds |
US20100307542A1 (en) * | 2009-06-05 | 2010-12-09 | Kraft Foods Global Brands Llc | Method of Reducing Surface Oil on Encapsulated Material |
US8859003B2 (en) * | 2009-06-05 | 2014-10-14 | Intercontinental Great Brands Llc | Preparation of an enteric release system |
CA2835242A1 (en) | 2011-06-30 | 2013-01-03 | Genentech, Inc. | Anti-c-met antibody formulations |
US8859005B2 (en) | 2012-12-03 | 2014-10-14 | Intercontinental Great Brands Llc | Enteric delivery of functional ingredients suitable for hot comestible applications |
MA39776A (fr) | 2014-03-24 | 2017-02-01 | Hoffmann La Roche | Traitement du cancer avec des antagonistes de c-met et corrélation de ces derniers avec l'expression de hgf |
EP2957557A1 (en) * | 2014-06-17 | 2015-12-23 | Novartis Tiergesundheit AG | New compounds |
JP6974331B2 (ja) | 2016-02-05 | 2021-12-01 | デナリ セラピューティクス インコーポレイテッドDenali Therapeutics Inc. | 化合物、組成物及び方法 |
HUE058802T2 (hu) | 2016-12-09 | 2022-09-28 | Denali Therapeutics Inc | RIPK1 inhibitorokként alkalmas vegyületek |
AU2018293627B2 (en) * | 2017-06-30 | 2022-07-21 | Elanco Animal Health Gmbh | New azaquinoline derivatives |
AU2023206890A1 (en) | 2022-01-12 | 2024-08-22 | Denali Therapeutics Inc. | Crystalline forms of (s)-5-benzyl-n-(5-methyl-4-oxo-2, 3,4,5- tetrahydropyrido [3,2-b] [l,4]oxazepin-3-yl)-4h-l,2,4-triazole-3-carboxamide |
Family Cites Families (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
PT731791E (pt) * | 1993-11-29 | 2000-11-30 | Merrell Pharma Inc | Novos derivados de benzeno-sulfonil-imina como inibidores da accao da il-1. |
US5559026A (en) * | 1994-10-31 | 1996-09-24 | American Cyanamid Company | Genes encoding a novel family of potassium channels |
DE19504379A1 (de) * | 1995-02-10 | 1996-08-14 | Hoechst Ag | Substituierte Benzolsulfonylharnstoffe und -thioharnstoffe, Verfahren zu ihrer Herstellung und ihre Verwendung zur Herstellung pharmazeutischer Präparate sowie sie enthaltende pharmazeutische Präparate |
PT807629E (pt) * | 1996-05-15 | 2004-07-30 | Aventis Pharma Gmbh | Cromanos substituidos por sulfonamidas processo para a sua preparacao a sua utilizacao como medicamentos ou agentes de diagnostico bem como medicamentos que os contem |
DE19706675A1 (de) | 1997-02-20 | 1998-08-27 | Hoechst Ag | Sulfonamid-substituierte Chromane, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament |
DE19707656A1 (de) | 1997-02-26 | 1998-08-27 | Hoechst Ag | Sulfonamid-substituierte anellierte 7-Ring-Verbindungen, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltende pharmazeutische Zubereitungen |
DE19742508A1 (de) * | 1997-09-26 | 1999-04-01 | Hoechst Marion Roussel De Gmbh | Sulfonamid-substituierte Chromane, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltende pharmazeutische Zubereitungen |
DE19742509A1 (de) | 1997-09-26 | 1999-04-01 | Hoechst Marion Roussel De Gmbh | Sulfonamid-substituierte Chromane, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltende pharmazeutische Zubereitungen |
DE19748469A1 (de) * | 1997-11-03 | 1999-05-06 | Hoechst Marion Roussel De Gmbh | Sulfonamid-substituierte Benzopyranderivate, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament sowie sie enthaltende pharmazeutische Zubereitungen |
-
1998
- 1998-12-17 DE DE19858253A patent/DE19858253A1/de not_active Withdrawn
-
1999
- 1999-12-07 IL IL14371799A patent/IL143717A0/xx not_active IP Right Cessation
- 1999-12-07 RU RU2001119996/15A patent/RU2238090C2/ru not_active IP Right Cessation
- 1999-12-07 KR KR1020017007420A patent/KR20010089574A/ko not_active Application Discontinuation
- 1999-12-07 NZ NZ512408A patent/NZ512408A/en unknown
- 1999-12-07 CN CNB998145823A patent/CN1170528C/zh not_active Expired - Fee Related
- 1999-12-07 TR TR2001/01750T patent/TR200101750T2/xx unknown
- 1999-12-07 HU HU0200152A patent/HUP0200152A3/hu unknown
- 1999-12-07 PL PL99349511A patent/PL349511A1/xx not_active Application Discontinuation
- 1999-12-07 EP EP99958170A patent/EP1140042B1/de not_active Expired - Lifetime
- 1999-12-07 BR BR9916190-7A patent/BR9916190A/pt not_active Application Discontinuation
- 1999-12-07 JP JP2000587750A patent/JP2002532412A/ja not_active Ceased
- 1999-12-07 DE DE59914712T patent/DE59914712D1/de not_active Expired - Lifetime
- 1999-12-07 AU AU15595/00A patent/AU1559500A/en not_active Abandoned
- 1999-12-07 CA CA002355300A patent/CA2355300A1/en not_active Abandoned
- 1999-12-07 WO PCT/EP1999/009547 patent/WO2000035429A1/de active IP Right Grant
- 1999-12-07 CZ CZ20012125A patent/CZ20012125A3/cs unknown
- 1999-12-07 SK SK856-2001A patent/SK8562001A3/sk unknown
- 1999-12-07 AT AT99958170T patent/ATE390130T1/de not_active IP Right Cessation
- 1999-12-15 AR ARP990106411A patent/AR021690A1/es unknown
- 1999-12-16 US US09/461,806 patent/US6335363B1/en not_active Expired - Lifetime
-
2001
- 2001-05-04 ZA ZA200103620A patent/ZA200103620B/en unknown
- 2001-06-14 HR HR20010442A patent/HRPK20010442B1/xx not_active IP Right Cessation
- 2001-06-15 NO NO20012976A patent/NO20012976L/no not_active Application Discontinuation
- 2001-11-16 US US09/987,809 patent/US20020055537A1/en not_active Abandoned
-
2002
- 2002-05-04 HK HK02103407.9A patent/HK1041647B/zh not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
HK1041647A1 (en) | 2002-07-19 |
US6335363B1 (en) | 2002-01-01 |
NZ512408A (en) | 2003-10-31 |
DE19858253A1 (de) | 2000-06-21 |
HRPK20010442B1 (en) | 2003-10-31 |
DE59914712D1 (de) | 2008-05-08 |
WO2000035429A1 (de) | 2000-06-22 |
ATE390130T1 (de) | 2008-04-15 |
IL143717A0 (en) | 2002-04-21 |
HK1041647B (zh) | 2005-04-01 |
CN1330540A (zh) | 2002-01-09 |
CZ20012125A3 (cs) | 2001-09-12 |
JP2002532412A (ja) | 2002-10-02 |
BR9916190A (pt) | 2001-09-11 |
SK8562001A3 (en) | 2001-12-03 |
AU1559500A (en) | 2000-07-03 |
NO20012976D0 (no) | 2001-06-15 |
HRP20010442A2 (en) | 2002-06-30 |
CA2355300A1 (en) | 2000-06-22 |
ZA200103620B (en) | 2002-06-04 |
EP1140042B1 (de) | 2008-03-26 |
CN1170528C (zh) | 2004-10-13 |
US20020055537A1 (en) | 2002-05-09 |
EP1140042A1 (de) | 2001-10-10 |
HUP0200152A2 (hu) | 2002-05-29 |
TR200101750T2 (tr) | 2002-01-21 |
NO20012976L (no) | 2001-08-06 |
HUP0200152A3 (en) | 2003-01-28 |
KR20010089574A (ko) | 2001-10-06 |
PL349511A1 (en) | 2002-07-29 |
RU2238090C2 (ru) | 2004-10-20 |
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