ES2123558T3 - Antigenos peptidicos del vhc y procedimiento para la determinacion del vhc. - Google Patents

Antigenos peptidicos del vhc y procedimiento para la determinacion del vhc.

Info

Publication number
ES2123558T3
ES2123558T3 ES92913343T ES92913343T ES2123558T3 ES 2123558 T3 ES2123558 T3 ES 2123558T3 ES 92913343 T ES92913343 T ES 92913343T ES 92913343 T ES92913343 T ES 92913343T ES 2123558 T3 ES2123558 T3 ES 2123558T3
Authority
ES
Spain
Prior art keywords
hcv
determination
procedure
antigens
peptidic antigens
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES92913343T
Other languages
English (en)
Other versions
ES2123558T5 (es
Inventor
Christoph Seidel
Gertraud Ehrlich-Weinreich
Hubert Bayer
Ursula-Henrike Wienhues
Gunther-Gerhard Jung
Hans Georg Ihlenfeldt
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Roche Diagnostics GmbH
Original Assignee
Boehringer Mannheim GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27202683&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ES2123558(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Boehringer Mannheim GmbH filed Critical Boehringer Mannheim GmbH
Application granted granted Critical
Publication of ES2123558T3 publication Critical patent/ES2123558T3/es
Publication of ES2123558T5 publication Critical patent/ES2123558T5/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011—Details
    • C12N2770/24011—Flaviviridae
    • C12N2770/24211—Hepacivirus, e.g. hepatitis C virus, hepatitis G virus
    • C12N2770/24222—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Virology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Oncology (AREA)
  • Veterinary Medicine (AREA)
  • Peptides Or Proteins (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

Abstract

SE DESCRIBEN NUEVOS ANTIGENOS DEL PEPTIDO HCV, QUE REPRESENTAN SECUENCIAS PARCIALES DEL C-100-3 Y EL ENV/CORE, CON LA ZONA C. ESTOS ANTIGENOS DE PEPTIDO SON ADECUADOS PARA LA DETERMINACION DE ANTICUERPOS HCV, COMO INMUNOGENES PARA LA OBTENCION DE ANTICUERPOS CONTRA HCV, Y COMO VACUNAS PARA LA OBTENCION DE SUSTANCIAS INYECTABLES CONTRA EL HCV.
ES92913343T 1991-07-04 1992-06-30 Antigenos peptidicos del vhc y procedimiento para la determinacion del vhc. Expired - Lifetime ES2123558T5 (es)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
DE4122160 1991-07-04
DE4122160 1991-07-04
DE4141304 1991-12-14
DE4141304 1991-12-14
DE4209215 1992-03-21
DE4209215A DE4209215A1 (de) 1991-07-04 1992-03-21 Hcv peptidantigene und verfahren zur bestimmung von hcv

Publications (2)

Publication Number Publication Date
ES2123558T3 true ES2123558T3 (es) 1999-01-16
ES2123558T5 ES2123558T5 (es) 2004-06-01

Family

ID=27202683

Family Applications (1)

Application Number Title Priority Date Filing Date
ES92913343T Expired - Lifetime ES2123558T5 (es) 1991-07-04 1992-06-30 Antigenos peptidicos del vhc y procedimiento para la determinacion del vhc.

Country Status (10)

Country Link
US (3) US6183949B1 (es)
EP (2) EP0881231A3 (es)
JP (1) JP2774872B2 (es)
KR (1) KR970010925B1 (es)
AT (1) ATE171710T1 (es)
AU (1) AU652851B2 (es)
CA (1) CA2089576A1 (es)
DE (2) DE4209215A1 (es)
ES (1) ES2123558T5 (es)
WO (1) WO1993001210A2 (es)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2049679C (en) * 1990-08-24 2005-06-21 Sushil G. Devare Hepatitis c assay utilizing recombinant antigens
DE4209215A1 (de) 1991-07-04 1993-01-07 Boehringer Mannheim Gmbh Hcv peptidantigene und verfahren zur bestimmung von hcv
CN1053196C (zh) * 1992-07-16 2000-06-07 株式会社先端生命科学研究所 用于丙型肝炎病毒分类的抗原肽, 含有所述肽的药盒及用所述肽进行分类的方法
DE4240980A1 (de) * 1992-08-07 1994-02-10 Boehringer Mannheim Gmbh HCV Peptidantigene und Verfahren zur Bestimmung von HCV
JP3751315B2 (ja) 1993-05-05 2006-03-01 コモン サーヴィシス エージェンシー Ｃ型肝炎ウイルス４、５及び６型
WO1995012677A2 (en) * 1993-11-04 1995-05-11 Innogenetics N.V. Immunodominant human t-cell epitopes of hepatitis c virus
AU697171B2 (en) * 1994-04-08 1998-10-01 Government Of The United States Of America, As Represented By The Secretary Of The Department Of Health And Human Services, The Hepatitis C virus core peptide for stimulation of cytotoxic T lymphocytes and diagnosis of HCV exposure
JP3217600B2 (ja) * 1994-07-12 2001-10-09 株式会社先端生命科学研究所 非ａ非ｂ型肝炎ウイルス関連抗原のイムノアッセイ、それに使用するモノクローナル抗体、およびこの抗体を産生するハイブリドーマ
BR9506059A (pt) * 1994-07-29 1997-10-28 Innogenetics Nv Proteinas envelopes purificadas de virus c para uso de diagnóstico e terapêutico
KR19990008122A (ko) * 1995-04-28 1999-01-25 곤도도시유키 항원 펩타이드 화합물 및 면역학적 측정방법
EP0947525A1 (en) * 1998-03-27 1999-10-06 Innogenetics N.V. Epitopes in viral envelope proteins and specific antibodies directed against these epitopes: use for detection of HCV viral antigen in host tissue
WO2000007023A1 (fr) * 1998-07-30 2000-02-10 Advanced Life Science Institute, Inc. Procede pour la determination de l'hepatite a virus de type c
JP2003510075A (ja) * 1999-09-29 2003-03-18 ディグノキュアー・インコーポレーテッド 良性および悪性の前立腺組織におけるｐｃａ３メッセンジャーｒｎａ種
US7049060B2 (en) * 2001-11-05 2006-05-23 Ortho-Clinical Diagnostics, Inc. HCV anti-core monoclonal antibodies
EP1357127A1 (de) * 2002-04-10 2003-10-29 Immusystems GmbH CD4+ T-Lymphozyten spezifische Hepatitis C Virus-Epitope
WO2006058287A2 (en) * 2004-11-26 2006-06-01 The Texas A & M University System Immunologic assay for detection of autoantibodies to folate binding protein
US8865398B2 (en) 2006-09-01 2014-10-21 Abbott Laboratories Combination hepatitis C virus antigen and antibody detection method
WO2009034190A2 (en) * 2007-09-14 2009-03-19 Genimmune N.V. Affinity tag
CN102123724B (zh) 2008-06-19 2018-05-01 变异生技公司 治疗流行性感冒的组合物和方法
US20100104555A1 (en) * 2008-10-24 2010-04-29 The Scripps Research Institute HCV neutralizing epitopes
CN103282375B (zh) 2010-12-02 2017-01-11 比奥诺尔免疫有限公司 肽支架设计
EP2780350B1 (en) 2011-11-18 2019-03-06 Variation Biotechnologies Inc. Synthetic derivatives of mpl and uses thereof
FR2984328B1 (fr) 2011-12-20 2016-12-30 Bio-Rad Innovations Procede de detection d'une infection par le virus de l'hepatite c

Family Cites Families (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3640412A1 (de) 1986-11-26 1988-06-09 Boehringer Mannheim Gmbh Verfahren zur bestimmung einer spezifisch bindefaehigen substanz
US5306620A (en) * 1987-07-08 1994-04-26 The Scripps Research Institute Antibodies that bind to a ligand-induced binding site on integrin and induce integrin activation
US5350671A (en) * 1987-11-18 1994-09-27 Chiron Corporation HCV immunoassays employing C domain antigens
HU220204B (hu) 1987-11-18 2001-11-28 Chiron Corp. HCV polipeptidek és HCV polinukleotidok, ilyen polinukleotidokat tartalmazó vektorok és ezekkel transzformált gazdasejtek, valamint HCV fertőzés kimutatására szolgáló diagnosztikumok és immunvizsgálati készlet
US5191064A (en) 1988-09-30 1993-03-02 The Research Foundation For Microbial Diseases (Osaka University) Non-a, non-b hepatitis virus antigen peptide
US5106727A (en) * 1989-04-27 1992-04-21 Life Technologies, Inc. Amplification of nucleic acid sequences using oligonucleotides of random sequences as primers
US6596476B1 (en) * 1989-12-22 2003-07-22 Abbott Laboratories Hepatitis C assay
US5106726A (en) * 1990-02-16 1992-04-21 United Biomedical, Inc. Synthetic peptides specific for the detection of antibodies to HCV
KR940000755B1 (ko) * 1990-02-16 1994-01-29 유나이티드 바이오메디칼 인코오포레이티드 Hcv에 대한 항체 검출, hcv 감염의 진단 및 백신으로서의 그 예방에 특히 적합한 합성 펩티드
US5747239A (en) * 1990-02-16 1998-05-05 United Biomedical, Inc. Synthetic peptides specific for the detection of antibodies to HCV, diagnosis of HCV infection and preventions thereof as vaccines
EP0445801A3 (en) * 1990-03-08 1992-07-01 Kuraray Co., Ltd. Peptide and its use
WO1991015516A2 (en) * 1990-04-06 1991-10-17 Genelabs Incorporated Hepatitis c virus epitopes
AU635124B2 (en) * 1990-04-16 1993-03-11 United Biomedical Inc. Synthetic peptides specific for the detection of antibodies to HCV, diagnosis of HCV infection and prevention thereof as vaccines
EP0464287A1 (en) * 1990-06-25 1992-01-08 The Research Foundation for Microbial Diseases of Osaka University Non-A, non-B hepatitis virus genomic cDNA and antigen polypeptide
CA2047792C (en) * 1990-07-26 2002-07-02 Chang Y. Wang Synthetic peptides specific for the detection of antibodies to hcv, diagnosis of hcv infection and prevention thereof as vaccines
US6172189B1 (en) * 1990-08-24 2001-01-09 Abbott Laboratories Hepatitis C assay utilizing recombinant antigens
DK0770679T4 (da) * 1990-11-03 2010-05-10 Siemens Healthcare Diagnostics HCV-specifikke peptider, sammensætninger dertil og anvendelse deraf
ATE144993T1 (de) * 1990-12-14 1996-11-15 Innogenetics Nv Synthetische antigene zum nachweis von antikörpern gegen hepatitis c-virus
AU1459792A (en) * 1991-01-14 1992-08-27 James N. Gamble Institute Of Medical Research Basic structural immunogenic polypeptides having epitopes for hcv, antibodies, polynucleotide sequences, vaccines and methods
US5574132A (en) * 1991-04-05 1996-11-12 Biochem Immunosystems Inc. Peptides and mixtures thereof for detecting antibodies to hepatitis C virus (HCV)
DE4209215A1 (de) 1991-07-04 1993-01-07 Boehringer Mannheim Gmbh Hcv peptidantigene und verfahren zur bestimmung von hcv
IL124567A (en) * 1998-05-20 2008-08-07 Abic Biolog Lab Ltd DNA sequences of HEMORRHAGIC ENTERITIS virus, proteins encoded by them and their various uses

Also Published As

Publication number Publication date
AU2197392A (en) 1993-02-11
EP0551460A1 (de) 1993-07-21
AU652851B2 (en) 1994-09-08
DE4209215A1 (de) 1993-01-07
WO1993001210A2 (de) 1993-01-21
JP2774872B2 (ja) 1998-07-09
CA2089576A1 (en) 1993-01-05
KR930702387A (ko) 1993-09-08
KR970010925B1 (ko) 1997-07-02
US6592871B1 (en) 2003-07-15
US6183949B1 (en) 2001-02-06
EP0881231A3 (de) 2004-02-04
DE59209512D1 (de) 1998-11-05
WO1993001210A3 (de) 1993-04-15
JPH05506462A (ja) 1993-09-22
EP0551460B2 (de) 2003-10-08
ATE171710T1 (de) 1998-10-15
ES2123558T5 (es) 2004-06-01
US20030198644A1 (en) 2003-10-23
EP0881231A2 (de) 1998-12-02
EP0551460B1 (de) 1998-09-30

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