ES2118372T3 - Nuevos receptores siete transmembrana v28. - Google Patents

Nuevos receptores siete transmembrana v28.

Info

Publication number
ES2118372T3
ES2118372T3 ES94903271T ES94903271T ES2118372T3 ES 2118372 T3 ES2118372 T3 ES 2118372T3 ES 94903271 T ES94903271 T ES 94903271T ES 94903271 T ES94903271 T ES 94903271T ES 2118372 T3 ES2118372 T3 ES 2118372T3
Authority
ES
Spain
Prior art keywords
transmembrana
disclosed
receptors
new receivers
transmembrane receptors
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES94903271T
Other languages
English (en)
Inventor
Ronald Godiska
Patrick W Gray
Vicki Louise Schweickart
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Icos Corp
Original Assignee
Icos Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=25525137&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ES2118372(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Icos Corp filed Critical Icos Corp
Application granted granted Critical
Publication of ES2118372T3 publication Critical patent/ES2118372T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705Receptors; Cell surface antigens; Cell surface determinants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Toxicology (AREA)
  • Cell Biology (AREA)
  • Veterinary Medicine (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Laminated Bodies (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Compounds Of Unknown Constitution (AREA)

Abstract

SE PRESENTAN SECUENCIAS DE DNA QUE CODIFICAN SIETE NUEVOS RECEPTORES DE TRANSMEMBRANA Y VARIANTES DE LOS MISMOS ASI COMO MATERIALES Y METODOS PARA LA PRODUCCION DE LOS MISMOS MEDIANTE TECNICAS RECOMBINANTES. SE PRESENTAN SUSTANCIAS ANTICUERPO ESPECIFICAS PARA CADA UNO DE LOS SIETE RECEPTORES DE TRANSMEMBRANA COMO UTILES PARA LA MODULACION DE LAS REACCIONES DE ENLACE LIGANDO/RECEPTOR DE LOS RECEPTORES.
ES94903271T 1992-11-17 1993-11-17 Nuevos receptores siete transmembrana v28. Expired - Lifetime ES2118372T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US97745292A 1992-11-17 1992-11-17

Publications (1)

Publication Number Publication Date
ES2118372T3 true ES2118372T3 (es) 1998-09-16

Family

ID=25525137

Family Applications (1)

Application Number Title Priority Date Filing Date
ES94903271T Expired - Lifetime ES2118372T3 (es) 1992-11-17 1993-11-17 Nuevos receptores siete transmembrana v28.

Country Status (9)

Country Link
US (2) US5759804A (es)
EP (2) EP0630405B1 (es)
JP (5) JPH07503145A (es)
AT (1) ATE164884T1 (es)
CA (1) CA2128208C (es)
DE (1) DE69317883T2 (es)
DK (1) DK0630405T3 (es)
ES (1) ES2118372T3 (es)
WO (1) WO1994012635A2 (es)

Families Citing this family (52)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0578784A4 (en) 1991-04-05 1994-11-02 Univ Columbia ODOR RECEPTORS AND THEIR APPLICATIONS.
ES2118372T3 (es) 1992-11-17 1998-09-16 Icos Corp Nuevos receptores siete transmembrana v28.
US6107475A (en) * 1992-11-17 2000-08-22 Icos Corporation Seven transmembrane receptors
AU5325694A (en) * 1992-11-25 1994-06-22 Brigham And Women's Hospital Epstein barr virus induced genes
US5545549A (en) * 1994-02-03 1996-08-13 Synaptic Pharmaceutical Corporation DNA encoding a human neuropeptide Y/peptide YY (Y2) receptor and uses thereof
US6537764B1 (en) 1995-01-19 2003-03-25 Children's Medical Center Corporation Method of identifying inhibitors of C—C chemokine receptor 3
US6806061B1 (en) 1995-01-19 2004-10-19 Children's Medical Center Corporation G protein-coupled receptor gene and methods of use therefor
WO1996039511A2 (en) * 1995-06-05 1996-12-12 Incyte Pharmaceuticals, Inc. A C5a-LIKE SEVEN TRANSMEMBRANE RECEPTOR
US6743594B1 (en) 1995-06-06 2004-06-01 Human Genome Sciences, Inc. Methods of screening using human G-protein chemokine receptor HDGNR10 (CCR5)
US5686597A (en) * 1995-06-06 1997-11-11 Incyte Pharmaceuticals, Inc. Thrombin receptor homolog
US6025154A (en) * 1995-06-06 2000-02-15 Human Genome Sciences, Inc. Polynucleotides encoding human G-protein chemokine receptor HDGNR10
AU7011896A (en) * 1995-08-29 1997-03-19 Chiron Corporation Human hypothalmic ("hr") receptor polypeptide compositions, methods and uses thereof
WO1997045543A2 (en) 1996-05-28 1997-12-04 The Government Of The United States Of America, As Represented By The Secretary Of Health And Human Services, National Institutes Of Health Cc chemokine receptor 5, antibodies thereto, transgenic animals
US6140064A (en) 1996-09-10 2000-10-31 Theodor-Kocher Institute Method of detecting or identifying ligands, inhibitors or promoters of CXC chemokine receptor 3
EP1114864B9 (en) 1996-12-13 2013-05-08 Schering Corporation Mammalian cell surface antigens, related reagents
US6737252B2 (en) 1997-07-25 2004-05-18 Schering Corporation 7 transmembrane receptor family member BLRX
US5874252A (en) * 1997-07-29 1999-02-23 Smithkline Beecham Corporation Splicing variant of the Epstein-Barr virus-induced G-protein coupled receptor
FR2771423A1 (fr) * 1997-11-21 1999-05-28 Transgene Sa Vecteurs permettant d'inhiber ou retarder la liaison d'un virus d'immunodeficience et/ou sa penetration dans une cellule cible
ATE383424T1 (de) * 1997-12-24 2008-01-15 Takeda Pharmaceutical Polypeptide, deren herstellung und verwendung
US6153441A (en) * 1998-02-17 2000-11-28 Smithkline Beecham Corporation Methods of screening for agonists and antagonists for human CCR7 receptor and CKβ-9 ligand and interaction thereof
EP1060248A1 (en) * 1998-03-04 2000-12-20 Icos Corporation Lectomedin materials and methods
WO2000000515A2 (en) * 1998-06-29 2000-01-06 Hyseq, Inc. A CHEMOKINE RECEPTOR OBTAINED FROM A cDNA LIBRARY OF FETAL LIVER-SPLEEN
JP2002531057A (ja) * 1998-08-19 2002-09-24 ミレニアム・ファーマシューティカルズ・インコーポレイテッド Edg受容体ファミリーに関連したgタンパク質結合受容体である14274受容体
AU774850B2 (en) * 1999-01-04 2004-07-08 Lexicon Pharmaceuticals, Inc. Human seven-transmembrane receptors
WO2000068250A1 (en) * 1999-05-12 2000-11-16 Smithkline Beecham Corporation 7tm receptor rat apj
WO2001004292A1 (en) * 1999-07-13 2001-01-18 Merck Patent Gmbh G-protein coupled receptor and dna sequences thereof
WO2001036473A2 (en) * 1999-11-16 2001-05-25 Pharmacia & Upjohn Company Human g protein-coupled receptors
US20030082534A1 (en) * 1999-11-16 2003-05-01 Peter Lind Novel G protein-coupled receptors
WO2001060406A1 (en) * 2000-02-18 2001-08-23 Millennium Pharmaceuticals, Inc. Therapeutic methods that target fractalkine or cx3cr1
EP1265925A2 (en) * 2000-02-23 2002-12-18 PHARMACIA & UPJOHN COMPANY G protein-coupled receptors
US20030077709A1 (en) * 2000-03-21 2003-04-24 Masazumi Kamohara Novel leukotriene B4 receptor
AU2001242749A1 (en) * 2000-03-23 2001-10-03 Takeda Chemical Industries Ltd. Peptide derivative
US7175988B2 (en) 2001-02-09 2007-02-13 Human Genome Sciences, Inc. Human G-protein Chemokine Receptor (CCR5) HDGNR10
US7393934B2 (en) 2001-12-21 2008-07-01 Human Genome Sciences, Inc. Human G-protein chemokine receptor (CCR5) HDGNR10
WO2003104484A1 (en) * 2002-06-10 2003-12-18 Metabolex, Inc. Methods of treating and diagnosing diabetes with cx3cr1 modulators
US7271209B2 (en) * 2002-08-12 2007-09-18 Exxonmobil Chemical Patents Inc. Fibers and nonwovens from plasticized polyolefin compositions
IL152824A (en) * 2002-11-13 2012-05-31 Mosaid Technologies Inc A socket that can be connected to and the network that uses it
WO2004106938A2 (en) * 2003-06-02 2004-12-09 Bayer Healthcare Ag Diagnostics and therapeutics for diseases associated with g protein-coupled p2y purinoreceptor 7 (p2y7)
WO2005040829A2 (en) * 2003-10-21 2005-05-06 Bayer Healthcare Ag Diagnostics and therapeutics for diseases associated with g protein-coupled receptor 17 (gpr17)
CA2559809A1 (en) 2004-03-12 2005-11-10 Human Genome Sciences, Inc. Antibodies against human g-protein chemokine receptor (ccr5) hdgnr10
DE602005024537D1 (de) 2004-04-27 2010-12-16 Takeda Pharmaceutical Neuer ligand eines g-protein-konjugierten rezeptorproteins und verwendung davon
ITMI20042007A1 (it) * 2004-10-21 2005-01-21 Consiglio Nazionale Ricerche "modulatori del ricettore gpr17 e loro impieghi terapeutici"
US8673848B2 (en) 2012-01-27 2014-03-18 Novartis Ag Synthetic apelin mimetics for the treatment of heart failure
EP1996619A4 (en) * 2006-02-14 2009-11-18 Geisinger Clinic GPCR RECEPTORS USED AS TARGETS FOR ANGIOGENESIS
US20100215663A1 (en) * 2006-02-15 2010-08-26 Northwestern University Methods and compositions for regulation of neurological conditions
JP5509709B2 (ja) 2009-07-24 2014-06-04 日清紡ケミカル株式会社 燃料電池セパレータ
UY35144A (es) 2012-11-20 2014-06-30 Novartis Ag Miméticos lineales sintéticos de apelina para el tratamiento de insuficiencia cardiaca
US8921307B2 (en) 2012-11-20 2014-12-30 Novartis Ag Synthetic linear apelin mimetics for the treatment of heart failure
US9340582B2 (en) 2013-07-25 2016-05-17 Novartis Ag Bioconjugates of synthetic apelin polypeptides
MX2016001020A (es) 2013-07-25 2016-08-03 Novartis Ag Polipeptidos ciclicos para el tratamiento de insuficiencia cardiaca.
ES2905554T3 (es) * 2015-09-03 2022-04-11 Ono Pharmaceutical Co Agente para aumentar la inmunidad frente al cáncer utilizando antagonista de Alergina-1
JOP20190187A1 (ar) 2017-02-03 2019-08-01 Novartis Ag مترافقات عقار جسم مضاد لـ ccr7

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1992017497A1 (en) * 1991-03-29 1992-10-15 Genentech, Inc. Human pf4a receptors and their use
WO1992018641A1 (en) * 1991-04-10 1992-10-29 The Trustees Of Boston University Interleukin-8 receptors and related molecules and methods
ES2118372T3 (es) 1992-11-17 1998-09-16 Icos Corp Nuevos receptores siete transmembrana v28.

Also Published As

Publication number Publication date
DK0630405T3 (da) 1999-01-04
JP2000350582A (ja) 2000-12-19
JP2004000268A (ja) 2004-01-08
US5759804A (en) 1998-06-02
US6348574B1 (en) 2002-02-19
EP0846762A3 (en) 1998-09-23
EP0630405A1 (en) 1994-12-28
CA2128208C (en) 2004-01-06
EP0630405B1 (en) 1998-04-08
CA2128208A1 (en) 1994-06-09
WO1994012635A3 (en) 1994-10-13
JP2006129879A (ja) 2006-05-25
DE69317883D1 (de) 1998-05-14
JPH07503145A (ja) 1995-04-06
EP0846762A2 (en) 1998-06-10
ATE164884T1 (de) 1998-04-15
DE69317883T2 (de) 1998-11-12
WO1994012635A2 (en) 1994-06-09
JP2004298202A (ja) 2004-10-28

Similar Documents

Publication Publication Date Title
ES2118372T3 (es) Nuevos receptores siete transmembrana v28.
ES2129622T3 (es) Receptores para interleuquina-10 de mamifero.
FI961251A (fi) Ihmisten metabotrooppiset glutamaattireseptorialatyypit(HMR4, HMR6, HMR7)ja niihin liittyvät DNA-yhdisteet
EP1028315A3 (en) Target specific screens and their use for discovering small organic molecular pharmacophores
DE69034269D1 (de) Neues Verfahren zur Erschliessung des immunologischen Repertoirs
AU8814191A (en) Cell-free receptor binding assays, the production and use thereof
ATE47915T1 (de) Traegermaterial zur verwendung fuer immunbestimmungen.
AU3395084A (en) Polypeptide-induced monoclonal receptors to protein ligands
AU639226B2 (en) Recombinant protein receptor
AU1527188A (en) Factor viii binding domain of von willebrand factor
MX9705172A (es) Polipeptido asociado a il-2r y moleculas de adn que codifican el mismo.
AU5305300A (en) Mammalian receptor proteins; related reagents and methods
DE69011719D1 (de) Verfahren zur Synthese von Acylamino-organosilicium-Verbindungen.
DE69023532D1 (de) Verfahren zur Synthese von Acylamino-Organosilicium-Verbindungen.
DE69010956D1 (de) Verfahren zur Synthese von Acylaminogruppen enthaltenden Siliziumverbindungen.
DE69019839D1 (de) Verfahren zur Synthese von cis-Olefinen.
DK561587A (da) Apparat til kontinuert blanding af partikelmaterialer

Legal Events

Date Code Title Description
FG2A Definitive protection

Ref document number: 630405

Country of ref document: ES