ES2118058T3 - Factor de crecimiento de las celulas t. - Google Patents
Factor de crecimiento de las celulas t.Info
- Publication number
- ES2118058T3 ES2118058T3 ES89117317T ES89117317T ES2118058T3 ES 2118058 T3 ES2118058 T3 ES 2118058T3 ES 89117317 T ES89117317 T ES 89117317T ES 89117317 T ES89117317 T ES 89117317T ES 2118058 T3 ES2118058 T3 ES 2118058T3
- Authority
- ES
- Spain
- Prior art keywords
- growth factor
- cells
- support
- present
- cell growth
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 102000000588 Interleukin-2 Human genes 0.000 title abstract 3
- 108010002350 Interleukin-2 Proteins 0.000 title abstract 3
- 210000004027 cell Anatomy 0.000 abstract 6
- 239000003102 growth factor Substances 0.000 abstract 2
- 230000035755 proliferation Effects 0.000 abstract 2
- 102000003886 Glycoproteins Human genes 0.000 abstract 1
- 108090000288 Glycoproteins Proteins 0.000 abstract 1
- 241000699670 Mus sp. Species 0.000 abstract 1
- 210000001744 T-lymphocyte Anatomy 0.000 abstract 1
- 230000001900 immune effect Effects 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 230000000638 stimulation Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
- C07K14/54—Interleukins [IL]
- C07K14/5425—IL-9
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
- C07K16/244—Interleukins [IL]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
- Y10S530/808—Materials and products related to genetic engineering or hybrid or fused cell technology, e.g. hybridoma, monoclonal products
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S930/00—Peptide or protein sequence
- Y10S930/01—Peptide or protein sequence
- Y10S930/14—Lymphokine; related peptides
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S930/00—Peptide or protein sequence
- Y10S930/01—Peptide or protein sequence
- Y10S930/14—Lymphokine; related peptides
- Y10S930/141—Interleukin
Abstract
LA PRESENTE INVENCION ES RELATIVA GENERALMENTE AL FACTOR DE CRECIMIENTO DE CELULAS T. MAS PARTICULARMENTE, LA PRESENTE INVENCION ES RELATIVA AL FACTOR DE CRECIMIENTO DE CELULAS T, LAS CUALES CONTIENEN UNA GLICOPROTEINA LA CUAL SOPORTA "INTERLEUQUIN2" E "INTERLEUQUIN-4" CON INDEPENCIA DEL DESARROLLO DE LA CELULA T DE SOPORTE, ESPECIALMENTE DE FUENTES HUMANAS Y DE RATONES Y ADEMAS LA CUAL ES CAPAZ DE AUMENTAR LA PROLIFERACION DE CELULAS QUE RESPONDEN A IL3- O IL4-. INCLUSO MAS PARTICULARMENTE, LA PRESENTE INVENCION ES RELATIVA AL FACTOR DE CRECIMIENTO DE LA CELULA DE SOPORTE P40, COMPOSICIONES FARMACEUTICAS DE EL, ANTICUERPOS PARA EL Y CLONES MODIFICADOS DE SU DNA. LA PRESENTE INVENCION TAMBIEN CONTEMPLA UN METODO PARA INDUCIR LA PROLIFERACION DE CELULAS DE APOYO T , ASI COMO CELULAS QUE RESPONDEN POR IL3- E IL4-. EL FACTOR DE CRECIMIENTO DE LAS CELULAS T DE APOYO AQUI CONTEMPLADO SE USA ENLA ESTIMULACION DE CELULAS ESPECIFICAS DEL SISTEMA INMUNOLOGICO, SOLO O EN COMBINACION CON IL3 O IL4.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US07/246,482 US5208218A (en) | 1988-09-19 | 1988-09-19 | T cell growth factor glycoproteins |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2118058T3 true ES2118058T3 (es) | 1998-09-16 |
Family
ID=22930867
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES89117317T Expired - Lifetime ES2118058T3 (es) | 1988-09-19 | 1989-09-19 | Factor de crecimiento de las celulas t. |
Country Status (12)
Country | Link |
---|---|
US (2) | US5208218A (es) |
EP (1) | EP0361284B1 (es) |
JP (1) | JP3223260B2 (es) |
AT (1) | ATE167519T1 (es) |
AU (1) | AU621661B2 (es) |
CA (1) | CA1341461C (es) |
DE (1) | DE68928710T2 (es) |
DK (1) | DK175845B1 (es) |
ES (1) | ES2118058T3 (es) |
IE (1) | IE81152B1 (es) |
IL (1) | IL91691A (es) |
PT (1) | PT91750B (es) |
Families Citing this family (18)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5587302A (en) * | 1988-09-19 | 1996-12-24 | Ludwig Institute For Cancer Research | T cell growth factor |
US5208218A (en) * | 1988-09-19 | 1993-05-04 | Ludwig Institute For Cancer Research | T cell growth factor glycoproteins |
US5414071A (en) * | 1989-05-23 | 1995-05-09 | Genetics Institute, Inc. | Human cytokine IL-9 |
US5580753A (en) * | 1989-05-23 | 1996-12-03 | Ludwig Institute For Cancer Research | DNA encoding the human cytokine, interleukin-9 |
WO1991007186A1 (en) * | 1989-11-21 | 1991-05-30 | The University Of Melbourne | Anti-inflammatory compositions and methods |
US5132109A (en) * | 1990-10-05 | 1992-07-21 | Ludwig Institute For Cancer Research | Method for inhibiting production of ige and method for enhancing production of igg using interleukin 9 and inhibitors thereof |
US5250295A (en) * | 1991-11-04 | 1993-10-05 | The Regents Of The Univ. Of California | Natural killer cell enhancing factor |
WO1994006906A1 (en) * | 1992-09-18 | 1994-03-31 | Merck & Co., Inc. | DNA ENCODING MURINE PRECURSOR INTERLEUKIN 1β CONVERTING ENZYME |
TW257792B (es) * | 1992-10-01 | 1995-09-21 | Lilly Co Eli | |
US5643881A (en) * | 1994-08-04 | 1997-07-01 | Tampa Bay Research Institute | Protein having anti-HIV activity and method for obtaining it |
US6037149A (en) * | 1995-08-24 | 2000-03-14 | Magainin Pharmaceuticals Inc. | DNA encoding human asthma associated factor 1 |
AU2007202406B2 (en) * | 1995-08-24 | 2010-08-12 | Ligand Pharmaceuticals Inc. | Asthma associated factors as targets for treating atopic allergies including asthma and related disorders |
ATE484294T1 (de) * | 1995-08-24 | 2010-10-15 | Genaera Corp | Anti-interleukin-9 antikörper oder anti- interleukin-9 rezeptor antikörper zur behandlung von bronchialem hyperreaktionsvermögen |
WO1998024904A2 (en) | 1996-12-02 | 1998-06-11 | Magainin Pharmaceuticals Inc. | Il-9 receptor variants, useful in treating and diagnosing atopic allergies including asthma and related disorders |
EP1401497B1 (en) | 2001-06-08 | 2012-01-11 | Genaera Corporation | Methods for the modulation of il-13 |
JP2005535572A (ja) * | 2002-04-12 | 2005-11-24 | メディミューン,インコーポレーテッド | 組換え抗インターロイキン−9抗体 |
DE602004028007D1 (de) * | 2003-05-14 | 2010-08-19 | Bayer Pharmaceuticals Corp | Interleukin-9 antagonist-muteine und ihre pharmakologischen anwendungsverfahren |
WO2009086516A1 (en) * | 2007-12-28 | 2009-07-09 | Kalos Therapeutics, Inc. | Anti-proliferative compounds and their use |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4636463A (en) * | 1984-04-05 | 1987-01-13 | Scripps Clinic And Research Foundation | Antibodies to human interleukin-2 induced by synthetic polypeptides |
US5006459A (en) * | 1986-03-31 | 1991-04-09 | T Cell Sciences, Inc. | Therapeutic and diagnostic methods using soluble T cell surface molecules |
US4935343A (en) * | 1986-08-08 | 1990-06-19 | Syntex (U.S.A.) Inc. | Monoclonal antibodies for interleukin-1β |
US5208218A (en) * | 1988-09-19 | 1993-05-04 | Ludwig Institute For Cancer Research | T cell growth factor glycoproteins |
JPH04500363A (ja) * | 1989-05-24 | 1992-01-23 | アボツト・ラボラトリーズ | 心房ペプチド誘導体 |
-
1988
- 1988-09-19 US US07/246,482 patent/US5208218A/en not_active Expired - Lifetime
-
1989
- 1989-09-15 US US07/408,155 patent/US5157112A/en not_active Expired - Lifetime
- 1989-09-18 DK DK198904588A patent/DK175845B1/da not_active IP Right Cessation
- 1989-09-18 CA CA000611819A patent/CA1341461C/en not_active Expired - Fee Related
- 1989-09-19 ES ES89117317T patent/ES2118058T3/es not_active Expired - Lifetime
- 1989-09-19 IL IL91691A patent/IL91691A/xx not_active IP Right Cessation
- 1989-09-19 JP JP24328789A patent/JP3223260B2/ja not_active Expired - Lifetime
- 1989-09-19 EP EP89117317A patent/EP0361284B1/en not_active Expired - Lifetime
- 1989-09-19 AU AU41563/89A patent/AU621661B2/en not_active Expired
- 1989-09-19 PT PT91750A patent/PT91750B/pt not_active IP Right Cessation
- 1989-09-19 DE DE68928710T patent/DE68928710T2/de not_active Expired - Lifetime
- 1989-09-19 AT AT89117317T patent/ATE167519T1/de not_active IP Right Cessation
- 1989-09-19 IE IE298389A patent/IE81152B1/en not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
IE892983L (en) | 1990-03-19 |
US5157112A (en) | 1992-10-20 |
EP0361284A3 (en) | 1990-09-05 |
ATE167519T1 (de) | 1998-07-15 |
IE81152B1 (en) | 2000-05-03 |
JP3223260B2 (ja) | 2001-10-29 |
DK458889D0 (da) | 1989-09-18 |
PT91750B (pt) | 1995-05-31 |
AU4156389A (en) | 1990-03-22 |
IL91691A (en) | 1997-07-13 |
AU621661B2 (en) | 1992-03-19 |
US5208218A (en) | 1993-05-04 |
DE68928710D1 (de) | 1998-07-23 |
JPH034796A (ja) | 1991-01-10 |
EP0361284A2 (en) | 1990-04-04 |
DK458889A (da) | 1990-03-20 |
IL91691A0 (en) | 1990-06-10 |
CA1341461C (en) | 2004-10-26 |
DK175845B1 (da) | 2005-03-29 |
PT91750A (pt) | 1990-03-30 |
DE68928710T2 (de) | 1999-02-11 |
EP0361284B1 (en) | 1998-06-17 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FG2A | Definitive protection |
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