ES2111637T3 - Derivado de benzotiadiazina. - Google Patents

Derivado de benzotiadiazina.

Info

Publication number
ES2111637T3
ES2111637T3 ES92910342T ES92910342T ES2111637T3 ES 2111637 T3 ES2111637 T3 ES 2111637T3 ES 92910342 T ES92910342 T ES 92910342T ES 92910342 T ES92910342 T ES 92910342T ES 2111637 T3 ES2111637 T3 ES 2111637T3
Authority
ES
Spain
Prior art keywords
methylene
substituted
lower alkyl
hydrate
halogen
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES92910342T
Other languages
English (en)
Inventor
Tomoyasu Ohno
Shingo Yano
Kosuke Fujiwara
Hirofusa Ajioka
Noriyuki Yamamoto
Shozo Yamada
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Taiho Pharmaceutical Co Ltd
Original Assignee
Taiho Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Taiho Pharmaceutical Co Ltd filed Critical Taiho Pharmaceutical Co Ltd
Application granted granted Critical
Publication of ES2111637T3 publication Critical patent/ES2111637T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D285/00—Heterocyclic compounds containing rings having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by groups C07D275/00 - C07D283/00
    • C07D285/15—Six-membered rings
    • C07D285/16—Thiadiazines; Hydrogenated thiadiazines
    • C07D285/18—1,2,4-Thiadiazines; Hydrogenated 1,2,4-thiadiazines
    • C07D285/20—1,2,4-Thiadiazines; Hydrogenated 1,2,4-thiadiazines condensed with carbocyclic rings or ring systems
    • C07D285/22—1,2,4-Thiadiazines; Hydrogenated 1,2,4-thiadiazines condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • C07D285/24—1,2,4-Thiadiazines; Hydrogenated 1,2,4-thiadiazines condensed with carbocyclic rings or ring systems condensed with one six-membered ring with oxygen atoms directly attached to the ring sulfur atom

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

UN DERIVADO DE BENZOTIADICINA REPRESENTADO POR LA FORMULA GENERAL (I), UN HIDRATO Y UNA ACIDO MAS SAL CONSIGUIENTE, Y UN REMEDIO PARA ULCERA PEPTICA QUE CONTIENE DICHO DERIVADO, DICHO HIDRATO O DICHA SAL COMO INGREDIENTE ACTIVO. EN LA FORMULA (I) X REPRESENTA METILENO O UN ATOMO DE NITROGENO CON ALQUILO INFERIOR SUSTITUIDO; Y Y Z REPRESENTAN CADA UNO METILENO O CARBONILO; A REPRESENTA FENILENO QUE PUEDE ESTAR SUSTITUIDO POR METOXICARBONILO; B REPRESENTA UN ALQUILENO INFERIOR O UN ALQUENILENO INFERIOR; R1 REPRESENTA HIDROGENO, ACETOXIACETILO, CICLOHEXILMETILO O BENCILO EN EL QUE EL ANILLO DE BENCENO PUEDE ESTAR SUSTITUIDO POR UN ALCOXI INFERIOR, HALOGENO, NITRO, ALQUILO INFERIOR, DIOXIDO DE METILENO O HIDROXILO; R2 REPRESENTA ALQUILO INFERIOR O FENILO; Y R3 REPRESENTA HIDROGENO, HALOGENO O ALCOXI INFERIOR, SIEMPRE QUE SE EXCLUYA EL CASO DONDE X, Y Y Z REPRESENTEN CADA UNO METILENO, A REPRESENTE FENILENO SIN SUSTITUIR, B REPRESENTE ALQUILENO INFERIOR, Y R1 REPRESENTE HIDROGENO.
ES92910342T 1991-05-24 1992-05-22 Derivado de benzotiadiazina. Expired - Lifetime ES2111637T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP14992791 1991-05-24

Publications (1)

Publication Number Publication Date
ES2111637T3 true ES2111637T3 (es) 1998-03-16

Family

ID=15485620

Family Applications (1)

Application Number Title Priority Date Filing Date
ES92910342T Expired - Lifetime ES2111637T3 (es) 1991-05-24 1992-05-22 Derivado de benzotiadiazina.

Country Status (12)

Country Link
US (1) US5401739A (es)
EP (1) EP0641789B1 (es)
KR (1) KR970002467B1 (es)
AT (1) ATE160776T1 (es)
AU (1) AU655986B2 (es)
CA (1) CA2109723C (es)
DE (1) DE69223422T2 (es)
DK (1) DK0641789T3 (es)
ES (1) ES2111637T3 (es)
GR (1) GR3025669T3 (es)
HU (1) HU211585A9 (es)
WO (1) WO1992020666A1 (es)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1351946A2 (en) * 2000-09-01 2003-10-15 Icos Corporation Materials and methods to potentiate cancer treatment
EP1660473A2 (en) 2003-03-24 2006-05-31 Luitpold Pharmaceuticals, Inc. Xanthones, thioxanthones and acridinones as dna-pk inhibitors
CN103058958A (zh) * 2011-10-22 2013-04-24 杭州福斯特药业有限公司 一种罗沙替丁醋酸酯盐酸盐的合成方法
CN105859654B (zh) * 2016-04-20 2018-01-12 安徽峆一药业股份有限公司 罗沙替丁中间体3‑(1‑哌啶甲基)苯酚的合成方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS59116277A (ja) * 1982-10-01 1984-07-05 ビ−チヤム・グル−プ・ピ−エルシ− 新規化合物
US4590192A (en) * 1982-10-01 1986-05-20 Beecham Group P.L.C. Benzisothiazoles, their pharmaceutical compositions, and method of use
US4558044A (en) * 1983-02-19 1985-12-10 Beecham Group P.L.C. 1,2,4-Benzothiadiazines
GB8328907D0 (en) * 1983-10-28 1983-11-30 Smith Kline French Lab Chemical compounds

Also Published As

Publication number Publication date
GR3025669T3 (en) 1998-03-31
CA2109723C (en) 1999-07-20
AU655986B2 (en) 1995-01-19
EP0641789A4 (en) 1994-04-18
HU211585A9 (en) 1995-12-28
EP0641789B1 (en) 1997-12-03
AU1792392A (en) 1992-12-30
CA2109723A1 (en) 1992-11-26
US5401739A (en) 1995-03-28
WO1992020666A1 (en) 1992-11-26
DE69223422D1 (de) 1998-01-15
ATE160776T1 (de) 1997-12-15
KR970002467B1 (ko) 1997-03-05
EP0641789A1 (en) 1995-03-08
DK0641789T3 (da) 1998-02-02
DE69223422T2 (de) 1998-04-09

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