ES2107832T3 - Una composicion farmaceutica para la administracion intranasal de hidroxocobalamina. - Google Patents

Una composicion farmaceutica para la administracion intranasal de hidroxocobalamina.

Info

Publication number
ES2107832T3
ES2107832T3 ES94918322T ES94918322T ES2107832T3 ES 2107832 T3 ES2107832 T3 ES 2107832T3 ES 94918322 T ES94918322 T ES 94918322T ES 94918322 T ES94918322 T ES 94918322T ES 2107832 T3 ES2107832 T3 ES 2107832T3
Authority
ES
Spain
Prior art keywords
pct
hydroxocobalamine
pharmaceutical composition
intranasal administration
date jun
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES94918322T
Other languages
English (en)
Inventor
Franciscus Wilhelmus He Merkus
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Application granted granted Critical
Publication of ES2107832T3 publication Critical patent/ES2107832T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7135—Compounds containing heavy metals
    • A61K31/714—Cobalamins, e.g. cyanocobalamin, i.e. vitamin B12
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0043—Nose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/02—Nutrients, e.g. vitamins, minerals

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Otolaryngology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Nutrition Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Saccharide Compounds (AREA)

Abstract

LA INVENCION SE REFIERE A UNA FORMULACION FARMACEUTICA, EN UNA COMPOSICION Y FORMA ADECUADAS PARA LA ADMINISTRACION NASAL, QUE CONTIENE HIDROXOCOBALAMINA DISUELTA EN UNA CONCENTRACION SUPERIOR A 1% (W/W), CON UNA VISCOSIDAD INFERIOR A 1000 CP.
ES94918322T 1993-12-20 1994-05-13 Una composicion farmaceutica para la administracion intranasal de hidroxocobalamina. Expired - Lifetime ES2107832T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
BE9301418A BE1007839A6 (nl) 1993-12-20 1993-12-20 Farmaceutische compositie voor de nasale toediening van hydroxocobalamine.

Publications (1)

Publication Number Publication Date
ES2107832T3 true ES2107832T3 (es) 1997-12-01

Family

ID=3887657

Family Applications (1)

Application Number Title Priority Date Filing Date
ES94918322T Expired - Lifetime ES2107832T3 (es) 1993-12-20 1994-05-13 Una composicion farmaceutica para la administracion intranasal de hidroxocobalamina.

Country Status (11)

Country Link
US (1) US5801161A (es)
EP (1) EP0735859B1 (es)
JP (1) JP3623962B2 (es)
AT (1) ATE156014T1 (es)
AU (1) AU6969994A (es)
BE (1) BE1007839A6 (es)
DE (1) DE69404675T2 (es)
DK (1) DK0735859T3 (es)
ES (1) ES2107832T3 (es)
GR (1) GR3025014T3 (es)
WO (1) WO1995017164A1 (es)

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6187790B1 (en) 1999-03-04 2001-02-13 Neal R. Cutler Use of cilostazol for treatment of sexual dysfunction
US6132757A (en) 1998-05-01 2000-10-17 Neal R. Cutler Treatment of sexual dysfunction in certain patient groups
US6426084B1 (en) * 2000-06-19 2002-07-30 Neal R. Cutler Treatment of sexual dysfunction in certain patient groups
WO2000038696A1 (en) * 1998-12-28 2000-07-06 Allergy Limited, Llc Cyanocobalamin (vitamin b12) treatment in allergic disease
US6562838B2 (en) * 2001-01-26 2003-05-13 R. T. Alamo Ventures I, L.L.C. Treatment of cardiovascular disease with quinolinone enantiomers
US6458804B1 (en) 2001-01-26 2002-10-01 R.T. Alamo Venturesi, Llc Methods for the treatment of central nervous system disorders in certain patient groups
US6451813B1 (en) 2001-01-26 2002-09-17 R. T. Alamo Ventures I, Llc Treatment of gastroparesis in certain patient groups
US20030096748A1 (en) * 2001-06-04 2003-05-22 The Regents Of The University Of Michigan Methods and compositions for the treatment of diseases associated with signal transduction aberrations
US7041677B2 (en) * 2002-03-01 2006-05-09 R.T. Alamo Ventures I, Llc Use of monochloroflosequinan in the treatment of sexual dysfunction
US7208628B2 (en) * 2002-05-13 2007-04-24 Kansas State University Research Foundation Compositions and methods for the treatment of hepatitis C virus infection
US7074893B2 (en) * 2002-06-03 2006-07-11 Regents Of The University Of Michigan Methods and compositions for the treatment of diseases associated with signal transduction aberrations
US7404489B1 (en) 2003-03-04 2008-07-29 Qol Medical, Llc Cyanocobalamin low viscosity aqueous formulations for intranasal delivery
US7229636B1 (en) 2003-03-04 2007-06-12 Nastech Pharmaceutical Company Inc. Cyanocobalamin low viscosity aqueous formulations for intranasal delivery
US20050032740A1 (en) * 2003-08-06 2005-02-10 Balaji Venkataraman Vitamin compositions for the treatment and prevention of vascular disease and dementia
US20050032741A1 (en) * 2003-08-06 2005-02-10 Balaji Venkataraman Vitamin Compositions
US20050089558A1 (en) * 2003-10-28 2005-04-28 Alamo Pharmaceuticals, Llc Compositions and methods for the co-formulation and administration of tramadol and propoxyphene
US20050153946A1 (en) * 2003-12-24 2005-07-14 Collegium Pharmaceuticals, Inc. Temperature-stable formulations, and methods of development thereof
CA2623215A1 (en) * 2004-09-23 2006-12-28 The Regents Of The University Of California Assay for vitamin b12 absorption and method of making labeled vitamin b12
JP2009504767A (ja) 2005-08-17 2009-02-05 フレミング・アンド・カンパニー・ファーマシューティカルズ ビタミンｂ１２鼻用スプレーおよび使用方法
JP5769924B2 (ja) * 2006-06-23 2015-08-26 パル ファーマシューティカル， インコーポレーテッド 鼻内送達用シアノコバラミン低粘度水性製剤
AU2014202415B2 (en) * 2006-06-23 2016-02-18 Par Pharmaceutical, Inc Cyanocobalamin low viscosity aqueous formulations for intranasal delivery
CN101011409B (zh) * 2007-02-06 2010-08-11 浙江爱生药业有限公司 一种维生素b12滴鼻液组合物
DK2632430T3 (en) * 2010-10-29 2018-09-17 Troikaa Pharmaceuticals Ltd : NASAL COMPOSITIONS OF B12 VITAMIN
US9585908B1 (en) 2010-11-08 2017-03-07 Chromaceutical Advanced Technologies, Inc. Collyrium composition and method of using same
NL2010550C2 (en) 2012-11-30 2014-06-04 Klaas Alouis Riepma An intranasal pharmaceutical composition containing vitamin b12.
JP5797227B2 (ja) * 2013-05-21 2015-10-21 パル ファーマシューティカル， インコーポレーテッド 鼻内送達用シアノコバラミン低粘度水性製剤
JP6897971B2 (ja) 2015-05-15 2021-07-07 ザ リージェンツ オブ ザ ユニバーシティ オブ ミシガン 関節炎を処置するための、方法および組成物
NL2015506B1 (en) 2015-09-25 2017-04-20 Alouis Riepma Klaas Oral administration of Vitamin B12 dispersed in a hydrophobic continuous phase
US10723718B2 (en) 2017-11-07 2020-07-28 The Regents Of The University Of Michigan Small molecule inhibitors of shared epitope-calreticulin interactions and methods of use
GB202013645D0 (en) * 2020-08-31 2020-10-14 Innotesto Bvba Pharmacetical compositions for the nasal administration of a colbalamin compound
JP7038448B1 (ja) * 2021-07-19 2022-03-18 雅行 沼田 抗アレルギー用投与デバイス

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE788780A (fr) * 1971-09-21 1973-01-02 Rolland Sa A Procede pour le diagnostic de l'hypercyanurie
US4724231A (en) * 1985-04-16 1988-02-09 Nastech Pharmaceutical, Inc. Nasel compositions containing vitamin B12
DE3682862D1 (de) * 1985-04-16 1992-01-23 Nastech Pharm Co Aerosolmittel zur nasenverstaeubung von vitamin b 12.

Also Published As

Publication number Publication date
JP3623962B2 (ja) 2005-02-23
US5801161A (en) 1998-09-01
EP0735859A1 (en) 1996-10-09
DE69404675D1 (de) 1997-09-04
GR3025014T3 (en) 1998-01-30
JPH09507477A (ja) 1997-07-29
BE1007839A6 (nl) 1995-10-31
DE69404675T2 (de) 1997-11-27
AU6969994A (en) 1995-07-10
EP0735859B1 (en) 1997-07-30
DK0735859T3 (da) 1998-03-09
WO1995017164A1 (en) 1995-06-29
ATE156014T1 (de) 1997-08-15

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