ES2107668T3 - Liposomas, procedimiento para su preparacion y su uso en la elaboracion de un medicamento. - Google Patents

Liposomas, procedimiento para su preparacion y su uso en la elaboracion de un medicamento.

Info

Publication number
ES2107668T3
ES2107668T3 ES93913004T ES93913004T ES2107668T3 ES 2107668 T3 ES2107668 T3 ES 2107668T3 ES 93913004 T ES93913004 T ES 93913004T ES 93913004 T ES93913004 T ES 93913004T ES 2107668 T3 ES2107668 T3 ES 2107668T3
Authority
ES
Spain
Prior art keywords
preparation
liposomes
procedure
medicinal product
present
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES93913004T
Other languages
English (en)
Inventor
Gunther Maierhofer
Paul Hofer
Oswald Rottmann
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Dianorm G Maierhofer GmbH
Original Assignee
Dianorm G Maierhofer GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dianorm G Maierhofer GmbH filed Critical Dianorm G Maierhofer GmbH
Application granted granted Critical
Publication of ES2107668T3 publication Critical patent/ES2107668T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • A61K9/1277—Preparation processes; Proliposomes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • A61K9/1271—Non-conventional liposomes, e.g. PEGylated liposomes or liposomes coated or grafted with polymers
    • A61K9/1272—Non-conventional liposomes, e.g. PEGylated liposomes or liposomes coated or grafted with polymers comprising non-phosphatidyl surfactants as bilayer-forming substances, e.g. cationic lipids or non-phosphatidyl liposomes coated or grafted with polymers
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Dispersion Chemistry (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

LA PRESENTE INVENCION SE REFIERE A LIPOSOMAS QUE PUEDEN SER OBTENIDAS MEDIANTE MEZCLAS DE LIQUIDOS FORMADORES DE DOBLE CAPA, CONTENIENDO AL MENOS PARCIALMENTE CADENAS DE ACIDO GRASO NO SATURADO, CON UNA SOLUCION ACUOSA DE ACIDO BILIAR Y ENERGIA MECANICA SUPLEMENTARIA. ANTES DE LA MEZCLA, LOS LIPIDOS PUEDEN ESTAR PRESENTES POR SI MISMOS O DISUELTOS EN DISOLVENTES SOLUBLES EN AGUA. LA INVENCION SE REFIERE TAMBIEN A UN PROCEDIMIENTO PARA LA PREPARACION DE TALES LIPOSOMAS Y SU UTILIZACION EN LA PREPARACION DE MEDICAMENTOS.
ES93913004T 1992-07-08 1993-06-17 Liposomas, procedimiento para su preparacion y su uso en la elaboracion de un medicamento. Expired - Lifetime ES2107668T3 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE4222447 1992-07-08
DE4232231 1992-09-25

Publications (1)

Publication Number Publication Date
ES2107668T3 true ES2107668T3 (es) 1997-12-01

Family

ID=25916414

Family Applications (1)

Application Number Title Priority Date Filing Date
ES93913004T Expired - Lifetime ES2107668T3 (es) 1992-07-08 1993-06-17 Liposomas, procedimiento para su preparacion y su uso en la elaboracion de un medicamento.

Country Status (9)

Country Link
US (1) US5853753A (es)
EP (1) EP0648114B1 (es)
JP (1) JPH08509202A (es)
AT (1) ATE158175T1 (es)
AU (1) AU4327193A (es)
CA (1) CA2139757C (es)
DE (1) DE59307395D1 (es)
ES (1) ES2107668T3 (es)
WO (1) WO1994001089A1 (es)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9452179B2 (en) 2009-08-21 2016-09-27 Sequessome Technology Holdings Limited Vesicular formulations
US9555051B2 (en) 2012-03-29 2017-01-31 Sequessome Technology Holdings Limited Vesicular formulations
US10744090B2 (en) 2015-06-30 2020-08-18 Sequessome Technology Holdings Limited Multiphasic compositions

Families Citing this family (54)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6663885B1 (en) * 1993-03-15 2003-12-16 A. Natterman & Cie Gmbh Aqueous liposome system and a method for the preparation of such a liposome system
DE4308121A1 (de) * 1993-03-15 1994-09-22 Rhone Poulenc Rorer Gmbh Wäßriges Liposomensystem sowie Verfahren zur Herstellung eines derartigen Liposomensystems
EP0720854A1 (de) * 1995-01-04 1996-07-10 Medichemie Ag Verwendung von Gallensäuren zur Herstellung von Arzneimitteln zur Behandlung von Erkrankungen der Haut
DE19522693A1 (de) * 1995-06-22 1997-01-02 Dianorm G Maierhofer Gmbh Zusammensetzung zur Herstellung feindisperser Systeme und Verfahren zu ihrer Herstellung
DE19522694A1 (de) * 1995-06-22 1997-01-02 Vinas Jose Maria De Moragas Teerhaltige Zusammensetzung und diese enthaltende pharmazeutische und kosmetische Zubereitung
US6132789A (en) * 1995-12-15 2000-10-17 National Research Council Of Canada Archaeosomes, archaeosomes containing coenzyme Q10, and other types of liposomes containing coenzyme Q10 as adjuvants and as delivery vehicles
US6284375B1 (en) * 1996-10-18 2001-09-04 Tuo Jin Lipid vesicle system
KR100464601B1 (ko) * 1998-10-23 2004-12-31 이데아 악티엔게젤샤프트 페이로드를 증가시키고, 분리/결합율을 제어하기 위한 거대 분자 결합체 및 복합응집체의 생장, 시험 및 사용방법
EP1210046A4 (en) * 1999-06-22 2007-05-02 Res Dev Foundation IMPROVED DRESSING THAT CAN ACCELERATE THE HEALING OF INJURIES
US6703370B1 (en) 1999-10-27 2004-03-09 Bioenergy, Inc. Use of ribose to treat fibromyalgia
EP1095658A3 (en) * 1999-10-27 2002-10-23 Bioenergy Inc. Use of ribose to treat fibromyalgia
WO2002015895A2 (en) * 2000-08-24 2002-02-28 The Regents Of The University Of California Alpha-difluoromethylornithine (dfmo) use in the human prostate
TNSN02063A1 (en) * 2001-07-07 2005-12-23 Egyptian Natural Oil Co Natoil The medical effect of jojoba oil
DE10224612A1 (de) * 2002-06-04 2003-12-24 Lohmann Therapie Syst Lts Wirkstoffhaltige filmförmige Zubereitungen mit verbesserter chemischer Stabilität, und Verfahren zu deren Herstellung
US20040105881A1 (en) * 2002-10-11 2004-06-03 Gregor Cevc Aggregates with increased deformability, comprising at least three amphipats, for improved transport through semi-permeable barriers and for the non-invasive drug application in vivo, especially through the skin
US20040224010A1 (en) * 2002-11-15 2004-11-11 Optime Therapeutics, Inc. Ophthalmic liposome compositions and uses thereof
KR20040048728A (ko) * 2002-12-04 2004-06-10 현대자동차주식회사 그리스 도포가 용이한 볼트
KR20050092429A (ko) * 2003-01-22 2005-09-21 니찌방 가부시기가이샤 안질환 치료용 경피 흡수형 제제, 그 사용, 및 안질환치료약의 눈의 국소 조직으로의 이행 방법
CA2575706A1 (en) * 2004-08-02 2006-02-23 Bebaas, Inc. Vitamin b12 compositions
US20070082042A1 (en) * 2004-08-06 2007-04-12 Deok-Hoon Park Multiple-layered liposome and preparation method thereof
US7351423B2 (en) 2004-09-01 2008-04-01 Depuy Spine, Inc. Musculo-skeletal implant having a bioactive gradient
EP1811961A2 (en) * 2004-11-12 2007-08-01 Idea Ag Extended surface aggregates in the treatment of skin conditions
US20070178141A1 (en) * 2005-09-07 2007-08-02 Bebaas, Inc. Vitamin B12 compositions
US20130131007A1 (en) 2005-09-07 2013-05-23 Bebaas, Inc. Vitamin b12 compositions
US7638142B2 (en) * 2005-10-12 2009-12-29 Vitamin Science, Inc. Therapeutic composition for the treatment of dry eye syndrome
US20070224637A1 (en) * 2006-03-24 2007-09-27 Mcauliffe Joseph C Oxidative protection of lipid layer biosensors
US8309129B2 (en) 2007-05-03 2012-11-13 Bend Research, Inc. Nanoparticles comprising a drug, ethylcellulose, and a bile salt
US8703204B2 (en) 2007-05-03 2014-04-22 Bend Research, Inc. Nanoparticles comprising a cholesteryl ester transfer protein inhibitor and anon-ionizable polymer
KR100785656B1 (ko) * 2007-05-14 2007-12-17 재단법인서울대학교산학협력재단 소염제로 사용되는 소디움글리코콜레이트 또는 그 유도체
WO2008149230A2 (en) 2007-06-04 2008-12-11 Pfizer Products Inc. Nanoparticles comprising drug, a non-ionizable cellulosic polymer and tocopheryl polyethylene glycol succinate
EP2162120B1 (en) 2007-06-04 2016-05-04 Bend Research, Inc Nanoparticles comprising a non-ionizable cellulosic polymer and an amphiphilic non-ionizable block copolymer
EP2231169B1 (en) 2007-12-06 2016-05-04 Bend Research, Inc. Pharmaceutical compositions comprising nanoparticles and a resuspending material
EP2240162A4 (en) 2007-12-06 2013-10-09 Bend Res Inc NANOTE PARTICLES WITH A NON-IONIZABLE POLYMER AND AN AMIN-FUNCTIONALIZED METHACRYLATE COPOLYMER
DE102008006394A1 (de) * 2008-01-28 2009-07-30 Beiersdorf Ag Verwendung von Wirkstoffkomplexen aus Panthenol, Glycerin, Citrat und/oder Bisabolol gegen Pollenallergien
ES2330295B1 (es) 2008-06-06 2010-09-23 Laboratorios Alcala Farma, Sl Formulacion topica de ibuprofeno.
DE102008035834A1 (de) * 2008-07-31 2010-02-04 Coty Prestige Lancaster Group Gmbh Verfahren zur Herstellung von Liposomkomplexen mit unterschiedlichen Wirkstoffen und damit hergestellte Produkte, insbesondere kosmetische Produkte
CN105434354A (zh) * 2009-06-03 2016-03-30 斯昆申技术控股有限责任公司 用于治疗深部组织疼痛的制剂
CN102482666B (zh) 2009-07-06 2017-02-08 变异生物技术公司 制备囊泡的方法和由其产生的制剂
CA2803282C (en) * 2009-07-06 2018-05-01 David E. Anderson Methods for preparing vesicles and formulations produced therefrom
CN103096922B (zh) 2010-07-06 2019-08-06 变异生物技术公司 用于治疗流行性感冒的组合物和方法
BR112013017939B1 (pt) 2011-01-13 2022-11-16 Variation Biotechnologies Inc Composição imunogênica liofilizada termoestável, uso e método para preparação da mesma
JP6137836B2 (ja) * 2011-01-27 2017-05-31 サンスター株式会社 多価不飽和脂肪酸含有組成物
EP2802353A4 (en) 2012-01-12 2015-12-02 Variation Biotechnologies Inc COMPOSITIONS AND METHOD FOR THE TREATMENT OF VIRUS INFECTIONS
CN104244984B (zh) 2012-01-27 2020-03-31 变异生物技术公司 用于治疗剂的方法和组合物
ITFI20120044A1 (it) * 2012-03-01 2013-09-02 Biodue Spa Formulazione ad uso oftalmico comprendente olio di jojoba.
GB201206486D0 (en) * 2012-04-12 2012-05-30 Sequessome Technology Holdings Ltd Vesicular formulations and uses thereof
WO2015162552A2 (en) 2014-04-22 2015-10-29 Biodue S.P.A. Composition for topic use
WO2019129761A1 (en) 2017-12-27 2019-07-04 Ursapharm Arzneimittel Gmbh Compositions and methods for eye and nose care
AU2019391397B2 (en) * 2018-12-06 2023-06-15 Chemipal Global Entrepreneurship Ltd Vitamin D micro-emulsions and uses thereof
CN114173578A (zh) 2019-05-14 2022-03-11 迪美公司 用于治疗癌症的组合物和方法
JP2023505689A (ja) * 2019-12-09 2023-02-10 タイム,インコーポレーテッド 医薬組成物および方法
US10905698B1 (en) 2020-05-14 2021-02-02 Tyme, Inc. Methods of treating SARS-COV-2 infections
CN114134065B (zh) * 2021-09-30 2024-04-26 杭州优玛达生物科技有限公司 生物胞膜系统及其制备方法、应用
GB202202031D0 (en) * 2022-02-16 2022-03-30 Dr Weller Ltd Compositions for Vitamin D production

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL64397A0 (en) 1981-01-07 1982-02-28 Weder Hans G Process for the preparation of liposomal medicaments
US4666893A (en) * 1983-02-15 1987-05-19 St. Thomas Institute Methods of inducing resistance to bacterial and viral infections
JPS607932A (ja) 1983-06-29 1985-01-16 Dai Ichi Seiyaku Co Ltd リポソーム懸濁液およびその製法
JPS6295134A (ja) 1985-10-21 1987-05-01 Nippon Saafuakutanto Kogyo Kk リポソ−ムの製造法
US4999344A (en) * 1987-11-06 1991-03-12 The United States Of America As Represented By The Secretary Of The Army Phosphatidyl treatment of rapidly proliferating cells
DE4017979A1 (de) * 1990-06-05 1991-12-12 Meyer Lucas Gmbh & Co Lipid- bzw. phospholipid-zusammensetzungen sowie diese enthaltendes mittel zur behandlung von erkrankungen sowie auf die zellmembrane zurueckzufuehrende stoerungen
CA2067754C (en) 1990-08-24 2002-06-04 Gregor Cevc Preparation for the application of agents in mini-droplets

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9452179B2 (en) 2009-08-21 2016-09-27 Sequessome Technology Holdings Limited Vesicular formulations
US9555051B2 (en) 2012-03-29 2017-01-31 Sequessome Technology Holdings Limited Vesicular formulations
US10744090B2 (en) 2015-06-30 2020-08-18 Sequessome Technology Holdings Limited Multiphasic compositions
US11547665B2 (en) 2015-06-30 2023-01-10 Sequessome Technology Holdings Limited Multiphasic compositions

Also Published As

Publication number Publication date
EP0648114A1 (de) 1995-04-19
ATE158175T1 (de) 1997-10-15
DE59307395D1 (de) 1997-10-23
WO1994001089A1 (de) 1994-01-20
CA2139757C (en) 2009-04-14
US5853753A (en) 1998-12-29
CA2139757A1 (en) 1994-01-20
AU4327193A (en) 1994-01-31
JPH08509202A (ja) 1996-10-01
EP0648114B1 (de) 1997-09-17

Similar Documents

Publication Publication Date Title
AU4327193A (en) Liposomes, method of preparing them and their use in the preparation of drugs
DK0580817T3 (da) Farmaceutisk præparat og fremgangsmåde til fremstilling deraf
ES8407061A1 (es) Procedimiento para la obtencion de liposomas unilaminares.
ES8700931A1 (es) Procedimiento para preparar composiciones de uso cosmetico o farmaceutico a base de unas esferulas lipidicas que contienen un polimero de poliamida.
IE780464L (en) Liposome compositions
CA1262093C (en) STEROID LIPOSOMES
MY112093A (en) Cosmetic delivery system for salicylic acid and process for preparation of the same.
ES2159564T3 (es) Preparados farmaceuticos para principios activos dificilmente solubles.
EP0461630A3 (en) Production process of microspheres
EA199800745A1 (ru) Устовершенствования в области контрастных агентов
ES2029330T3 (es) Un procedimiento para solubilizar un farmaco anfifilo.
NO305557B1 (no) Amfifiliske imidazoliniumderivater og fremgangsmÕte for fremstilling av imidazoliniumion
DK544883A (da) Stabile plurilamellare vesikler
HU903559D0 (en) Process for the production of liposome and lipid complex preparations
ES2078510T3 (es) Dispersion acuosa de vesiculas de fosfolipidos, procedimiento para su fabricacion y su uso.
ES2136591T3 (es) Derivados de cefalosporina y procedimiento para su preparacion.
JPS5227721A (en) Process for preparation of substituted phosphonic acid derivatives
MY118989A (en) Process for the preparation of derivatives of fatty acids
GR3030726T3 (en) Aqueous liposomal system and process for preparing such a liposomal system.
AU1957388A (en) Drug emulsion
ES2054777T3 (es) Metodo para la preparacion de o-carboxiarilimidazolinonas.
ES483116A1 (es) Procedimiento para la preparacion de derivados de acidos aziridin-2-carboxilicos substituidos en n, inmunoestimulan- tes
ES2069990T3 (es) Acido acilaminoalquilidenhidroxibisfosfonico util en la terapia de enfermedades osteoarticulares.
JPS55129141A (en) Emulsifier composition
AR241179A1 (es) Un procedimiento para preparar acidos-2-hidroxi-4-alquildenciclohexanoalcanoicos que tienen un sustituyente acido mercaptoalcanoico en la posicion 3,y los esteres de alquilo(c1-c4)de los mismos.

Legal Events

Date Code Title Description
FG2A Definitive protection

Ref document number: 648114

Country of ref document: ES