ES2107668T3 - Liposomas, procedimiento para su preparacion y su uso en la elaboracion de un medicamento. - Google Patents
Liposomas, procedimiento para su preparacion y su uso en la elaboracion de un medicamento.Info
- Publication number
- ES2107668T3 ES2107668T3 ES93913004T ES93913004T ES2107668T3 ES 2107668 T3 ES2107668 T3 ES 2107668T3 ES 93913004 T ES93913004 T ES 93913004T ES 93913004 T ES93913004 T ES 93913004T ES 2107668 T3 ES2107668 T3 ES 2107668T3
- Authority
- ES
- Spain
- Prior art keywords
- preparation
- liposomes
- procedure
- medicinal product
- present
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 239000002502 liposome Substances 0.000 title abstract 3
- 238000002360 preparation method Methods 0.000 title abstract 3
- 238000000034 method Methods 0.000 title abstract 2
- 229940126601 medicinal product Drugs 0.000 title 1
- 150000002632 lipids Chemical class 0.000 abstract 2
- HSINOMROUCMIEA-FGVHQWLLSA-N (2s,4r)-4-[(3r,5s,6r,7r,8s,9s,10s,13r,14s,17r)-6-ethyl-3,7-dihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1h-cyclopenta[a]phenanthren-17-yl]-2-methylpentanoic acid Chemical compound C([C@@]12C)C[C@@H](O)C[C@H]1[C@@H](CC)[C@@H](O)[C@@H]1[C@@H]2CC[C@]2(C)[C@@H]([C@H](C)C[C@H](C)C(O)=O)CC[C@H]21 HSINOMROUCMIEA-FGVHQWLLSA-N 0.000 abstract 1
- 239000007864 aqueous solution Substances 0.000 abstract 1
- 239000003613 bile acid Substances 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 229940079593 drug Drugs 0.000 abstract 1
- 239000002904 solvent Substances 0.000 abstract 1
- 125000005314 unsaturated fatty acid group Chemical group 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
- A61K9/1277—Preparation processes; Proliposomes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
- A61K9/1271—Non-conventional liposomes, e.g. PEGylated liposomes or liposomes coated or grafted with polymers
- A61K9/1272—Non-conventional liposomes, e.g. PEGylated liposomes or liposomes coated or grafted with polymers comprising non-phosphatidyl surfactants as bilayer-forming substances, e.g. cationic lipids or non-phosphatidyl liposomes coated or grafted with polymers
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Dispersion Chemistry (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
LA PRESENTE INVENCION SE REFIERE A LIPOSOMAS QUE PUEDEN SER OBTENIDAS MEDIANTE MEZCLAS DE LIQUIDOS FORMADORES DE DOBLE CAPA, CONTENIENDO AL MENOS PARCIALMENTE CADENAS DE ACIDO GRASO NO SATURADO, CON UNA SOLUCION ACUOSA DE ACIDO BILIAR Y ENERGIA MECANICA SUPLEMENTARIA. ANTES DE LA MEZCLA, LOS LIPIDOS PUEDEN ESTAR PRESENTES POR SI MISMOS O DISUELTOS EN DISOLVENTES SOLUBLES EN AGUA. LA INVENCION SE REFIERE TAMBIEN A UN PROCEDIMIENTO PARA LA PREPARACION DE TALES LIPOSOMAS Y SU UTILIZACION EN LA PREPARACION DE MEDICAMENTOS.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE4222447 | 1992-07-08 | ||
| DE4232231 | 1992-09-25 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2107668T3 true ES2107668T3 (es) | 1997-12-01 |
Family
ID=25916414
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES93913004T Expired - Lifetime ES2107668T3 (es) | 1992-07-08 | 1993-06-17 | Liposomas, procedimiento para su preparacion y su uso en la elaboracion de un medicamento. |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US5853753A (es) |
| EP (1) | EP0648114B1 (es) |
| JP (1) | JPH08509202A (es) |
| AT (1) | ATE158175T1 (es) |
| AU (1) | AU4327193A (es) |
| CA (1) | CA2139757C (es) |
| DE (1) | DE59307395D1 (es) |
| ES (1) | ES2107668T3 (es) |
| WO (1) | WO1994001089A1 (es) |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9452179B2 (en) | 2009-08-21 | 2016-09-27 | Sequessome Technology Holdings Limited | Vesicular formulations |
| US9555051B2 (en) | 2012-03-29 | 2017-01-31 | Sequessome Technology Holdings Limited | Vesicular formulations |
| US10744090B2 (en) | 2015-06-30 | 2020-08-18 | Sequessome Technology Holdings Limited | Multiphasic compositions |
Families Citing this family (54)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6663885B1 (en) * | 1993-03-15 | 2003-12-16 | A. Natterman & Cie Gmbh | Aqueous liposome system and a method for the preparation of such a liposome system |
| DE4308121A1 (de) * | 1993-03-15 | 1994-09-22 | Rhone Poulenc Rorer Gmbh | Wäßriges Liposomensystem sowie Verfahren zur Herstellung eines derartigen Liposomensystems |
| EP0720854A1 (de) * | 1995-01-04 | 1996-07-10 | Medichemie Ag | Verwendung von Gallensäuren zur Herstellung von Arzneimitteln zur Behandlung von Erkrankungen der Haut |
| DE19522693A1 (de) * | 1995-06-22 | 1997-01-02 | Dianorm G Maierhofer Gmbh | Zusammensetzung zur Herstellung feindisperser Systeme und Verfahren zu ihrer Herstellung |
| DE19522694A1 (de) * | 1995-06-22 | 1997-01-02 | Vinas Jose Maria De Moragas | Teerhaltige Zusammensetzung und diese enthaltende pharmazeutische und kosmetische Zubereitung |
| EP0869773B1 (en) * | 1995-12-15 | 2004-03-24 | National Research Council Of Canada | Archaeosomes, archaeosomes containing coenzyme q 10, and other types of liposomes containing coenzyme q 10 as adjuvants and as delivery vehicles |
| US6284375B1 (en) * | 1996-10-18 | 2001-09-04 | Tuo Jin | Lipid vesicle system |
| MXPA00006196A (es) * | 1998-10-23 | 2003-07-21 | Idea Ag | Metodo para desarrollar, evaluar y utilizar asociaciones de macromoleculas y agregados complejos para obtener mejores tasas de asociacion/desasociacion controlable y carga efectiva. |
| CA2377371A1 (en) * | 1999-06-22 | 2000-12-28 | David N. Herndon | Enhanced wound coverage to enhance wound healing |
| US6703370B1 (en) | 1999-10-27 | 2004-03-09 | Bioenergy, Inc. | Use of ribose to treat fibromyalgia |
| EP1095658A3 (en) * | 1999-10-27 | 2002-10-23 | Bioenergy Inc. | Use of ribose to treat fibromyalgia |
| WO2002015895A2 (en) * | 2000-08-24 | 2002-02-28 | The Regents Of The University Of California | Alpha-difluoromethylornithine (dfmo) use in the human prostate |
| TNSN02063A1 (en) * | 2001-07-07 | 2005-12-23 | Egyptian Natural Oil Co Natoil | The medical effect of jojoba oil |
| DE10224612A1 (de) * | 2002-06-04 | 2003-12-24 | Lohmann Therapie Syst Lts | Wirkstoffhaltige filmförmige Zubereitungen mit verbesserter chemischer Stabilität, und Verfahren zu deren Herstellung |
| US20040105881A1 (en) * | 2002-10-11 | 2004-06-03 | Gregor Cevc | Aggregates with increased deformability, comprising at least three amphipats, for improved transport through semi-permeable barriers and for the non-invasive drug application in vivo, especially through the skin |
| US20040224010A1 (en) * | 2002-11-15 | 2004-11-11 | Optime Therapeutics, Inc. | Ophthalmic liposome compositions and uses thereof |
| KR20040048728A (ko) * | 2002-12-04 | 2004-06-10 | 현대자동차주식회사 | 그리스 도포가 용이한 볼트 |
| KR20130121196A (ko) * | 2003-01-22 | 2013-11-05 | 센주 세이야꾸 가부시키가이샤 | 안질환 치료용 경피 흡수형 제제, 그 사용, 및 안질환 치료약의 눈의 국소 조직으로의 이행 방법 |
| WO2006020291A2 (en) * | 2004-08-02 | 2006-02-23 | Bebaas, Inc. | Vitamin b12 compositions |
| JP4758915B2 (ja) * | 2004-08-06 | 2011-08-31 | バイオスペクトラム,インコーポレイテッド | 多重層リポソームおよびその製造方法 |
| US7351423B2 (en) | 2004-09-01 | 2008-04-01 | Depuy Spine, Inc. | Musculo-skeletal implant having a bioactive gradient |
| WO2006050926A2 (en) * | 2004-11-12 | 2006-05-18 | Idea Ag | Extended surface aggregates in the treatment of skin conditions |
| US20130131007A1 (en) | 2005-09-07 | 2013-05-23 | Bebaas, Inc. | Vitamin b12 compositions |
| US20070178141A1 (en) * | 2005-09-07 | 2007-08-02 | Bebaas, Inc. | Vitamin B12 compositions |
| US7638142B2 (en) * | 2005-10-12 | 2009-12-29 | Vitamin Science, Inc. | Therapeutic composition for the treatment of dry eye syndrome |
| US20070224637A1 (en) * | 2006-03-24 | 2007-09-27 | Mcauliffe Joseph C | Oxidative protection of lipid layer biosensors |
| US8703204B2 (en) | 2007-05-03 | 2014-04-22 | Bend Research, Inc. | Nanoparticles comprising a cholesteryl ester transfer protein inhibitor and anon-ionizable polymer |
| WO2008135828A2 (en) | 2007-05-03 | 2008-11-13 | Pfizer Products Inc. | Nanoparticles comprising a drug, ethylcellulose, and a bile salt |
| KR100785656B1 (ko) * | 2007-05-14 | 2007-12-17 | 재단법인서울대학교산학협력재단 | 소염제로 사용되는 소디움글리코콜레이트 또는 그 유도체 |
| WO2008149230A2 (en) | 2007-06-04 | 2008-12-11 | Pfizer Products Inc. | Nanoparticles comprising drug, a non-ionizable cellulosic polymer and tocopheryl polyethylene glycol succinate |
| EP2162120B1 (en) | 2007-06-04 | 2016-05-04 | Bend Research, Inc | Nanoparticles comprising a non-ionizable cellulosic polymer and an amphiphilic non-ionizable block copolymer |
| US9724362B2 (en) | 2007-12-06 | 2017-08-08 | Bend Research, Inc. | Pharmaceutical compositions comprising nanoparticles and a resuspending material |
| WO2009073216A1 (en) | 2007-12-06 | 2009-06-11 | Bend Research, Inc. | Nanoparticles comprising a non-ionizable polymer and an amine-functionalized methacrylate copolymer |
| DE102008006394A1 (de) * | 2008-01-28 | 2009-07-30 | Beiersdorf Ag | Verwendung von Wirkstoffkomplexen aus Panthenol, Glycerin, Citrat und/oder Bisabolol gegen Pollenallergien |
| ES2330295B1 (es) | 2008-06-06 | 2010-09-23 | Laboratorios Alcala Farma, Sl | Formulacion topica de ibuprofeno. |
| DE102008035834A1 (de) * | 2008-07-31 | 2010-02-04 | Coty Prestige Lancaster Group Gmbh | Verfahren zur Herstellung von Liposomkomplexen mit unterschiedlichen Wirkstoffen und damit hergestellte Produkte, insbesondere kosmetische Produkte |
| PL2437726T3 (pl) * | 2009-06-03 | 2018-12-31 | Sequessome Technology Holdings Limited | Formulacje do leczenia bólu tkanki głębokiej |
| WO2011005772A1 (en) * | 2009-07-06 | 2011-01-13 | Variation Biotechnologies, Inc. | Methods for preparing vesicles and formulations produced therefrom |
| ES2573427T3 (es) | 2009-07-06 | 2016-06-07 | Variation Biotechnologies Inc. | Procedimientos para preparar vesículas y formulaciones producidas a partir de las mismas |
| CA2840079C (en) | 2010-07-06 | 2018-07-03 | Variation Biotechnologies Inc. | Compositions and methods for treating influenza |
| WO2012097346A1 (en) | 2011-01-13 | 2012-07-19 | Variation Biotechnologies, Inc. | Compositions and methods for treating viral infections |
| JP6137836B2 (ja) * | 2011-01-27 | 2017-05-31 | サンスター株式会社 | 多価不飽和脂肪酸含有組成物 |
| CA2894442C (en) | 2012-01-12 | 2020-01-21 | Variation Biotechnologies Inc. | Compositions and methods for treating viral infections |
| US20150079077A1 (en) | 2012-01-27 | 2015-03-19 | Variation Biotechnologies, Inc. | Methods and compositions for therapeutic agents |
| ITFI20120044A1 (it) * | 2012-03-01 | 2013-09-02 | Biodue Spa | Formulazione ad uso oftalmico comprendente olio di jojoba. |
| GB201206486D0 (en) * | 2012-04-12 | 2012-05-30 | Sequessome Technology Holdings Ltd | Vesicular formulations and uses thereof |
| EP3134086A2 (en) | 2014-04-22 | 2017-03-01 | Biodue S.p.A. | Composition for topic use |
| WO2019129761A1 (en) | 2017-12-27 | 2019-07-04 | Ursapharm Arzneimittel Gmbh | Compositions and methods for eye and nose care |
| KR20210119386A (ko) * | 2018-12-06 | 2021-10-05 | 리피케어 라이프 사이언스 엘티디. | 비타민 d 마이크로 에멀션 및 이의 용도 |
| AU2020276605A1 (en) | 2019-05-14 | 2022-01-20 | Tyme, Inc. | Compositions and methods for treating cancer |
| US20210169903A1 (en) * | 2019-12-09 | 2021-06-10 | Tyme, Inc. | Pharmaceutical compositions and methods |
| US10905698B1 (en) | 2020-05-14 | 2021-02-02 | Tyme, Inc. | Methods of treating SARS-COV-2 infections |
| CN114134065B (zh) * | 2021-09-30 | 2024-04-26 | 杭州优玛达生物科技有限公司 | 生物胞膜系统及其制备方法、应用 |
| GB202202031D0 (en) * | 2022-02-16 | 2022-03-30 | Dr Weller Ltd | Compositions for Vitamin D production |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL64397A0 (en) * | 1981-01-07 | 1982-02-28 | Weder Hans G | Process for the preparation of liposomal medicaments |
| US4666893A (en) * | 1983-02-15 | 1987-05-19 | St. Thomas Institute | Methods of inducing resistance to bacterial and viral infections |
| JPS607932A (ja) | 1983-06-29 | 1985-01-16 | Dai Ichi Seiyaku Co Ltd | リポソーム懸濁液およびその製法 |
| JPS6295134A (ja) | 1985-10-21 | 1987-05-01 | Nippon Saafuakutanto Kogyo Kk | リポソ−ムの製造法 |
| US4999344A (en) * | 1987-11-06 | 1991-03-12 | The United States Of America As Represented By The Secretary Of The Army | Phosphatidyl treatment of rapidly proliferating cells |
| DE4017979A1 (de) * | 1990-06-05 | 1991-12-12 | Meyer Lucas Gmbh & Co | Lipid- bzw. phospholipid-zusammensetzungen sowie diese enthaltendes mittel zur behandlung von erkrankungen sowie auf die zellmembrane zurueckzufuehrende stoerungen |
| CA2067754C (en) | 1990-08-24 | 2002-06-04 | Gregor Cevc | Preparation for the application of agents in mini-droplets |
-
1993
- 1993-06-17 ES ES93913004T patent/ES2107668T3/es not_active Expired - Lifetime
- 1993-06-17 WO PCT/EP1993/001545 patent/WO1994001089A1/de not_active Ceased
- 1993-06-17 AT AT93913004T patent/ATE158175T1/de active
- 1993-06-17 JP JP6502866A patent/JPH08509202A/ja active Pending
- 1993-06-17 CA CA002139757A patent/CA2139757C/en not_active Expired - Lifetime
- 1993-06-17 DE DE59307395T patent/DE59307395D1/de not_active Expired - Lifetime
- 1993-06-17 AU AU43271/93A patent/AU4327193A/en not_active Abandoned
- 1993-06-17 EP EP93913004A patent/EP0648114B1/de not_active Expired - Lifetime
-
1997
- 1997-02-18 US US08/800,802 patent/US5853753A/en not_active Expired - Lifetime
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9452179B2 (en) | 2009-08-21 | 2016-09-27 | Sequessome Technology Holdings Limited | Vesicular formulations |
| US9555051B2 (en) | 2012-03-29 | 2017-01-31 | Sequessome Technology Holdings Limited | Vesicular formulations |
| US10744090B2 (en) | 2015-06-30 | 2020-08-18 | Sequessome Technology Holdings Limited | Multiphasic compositions |
| US11547665B2 (en) | 2015-06-30 | 2023-01-10 | Sequessome Technology Holdings Limited | Multiphasic compositions |
Also Published As
| Publication number | Publication date |
|---|---|
| ATE158175T1 (de) | 1997-10-15 |
| CA2139757A1 (en) | 1994-01-20 |
| CA2139757C (en) | 2009-04-14 |
| US5853753A (en) | 1998-12-29 |
| DE59307395D1 (de) | 1997-10-23 |
| EP0648114A1 (de) | 1995-04-19 |
| WO1994001089A1 (de) | 1994-01-20 |
| JPH08509202A (ja) | 1996-10-01 |
| EP0648114B1 (de) | 1997-09-17 |
| AU4327193A (en) | 1994-01-31 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG2A | Definitive protection |
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