ES2104639T3 - Adnc para un peptido natriuretico de tipo c de rata, y proteina precursora. - Google Patents

Adnc para un peptido natriuretico de tipo c de rata, y proteina precursora.

Info

Publication number
ES2104639T3
ES2104639T3 ES91115393T ES91115393T ES2104639T3 ES 2104639 T3 ES2104639 T3 ES 2104639T3 ES 91115393 T ES91115393 T ES 91115393T ES 91115393 T ES91115393 T ES 91115393T ES 2104639 T3 ES2104639 T3 ES 2104639T3
Authority
ES
Spain
Prior art keywords
cdna
precursor protein
natriuretic peptide
rat type
precursor
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES91115393T
Other languages
English (en)
Inventor
Hisayuki Matsuo
Masayasu Kojima
Kenji Kangawa
Naoto Minamino
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Suntory Ltd
Original Assignee
Suntory Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Suntory Ltd filed Critical Suntory Ltd
Application granted granted Critical
Publication of ES2104639T3 publication Critical patent/ES2104639T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/58—Atrial natriuretic factor complex; Atriopeptin; Atrial natriuretic peptide [ANP]; Cardionatrin; Cardiodilatin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/10—Antioedematous agents; Diuretics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/12—Antidiuretics, e.g. drugs for diabetes insipidus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Abstract

SE PRESENTAN UN CADN QUE CODIFICA UN CNP DERIVADO DIFERENCIAL (RCNP: PEPTIDO NATRIURETICO DEL TIPO C) Y UNA PROTEINA PRECURSORA DE CNP DERIVADO DIFERENCIAL Y DERIVADOS DE LA MISMA. EL PRECURSOR DE CNP DERIVADO DIFERENCIAL VIENE REPRESENTADO POR LA SIGUIENTE SECUENCIA AMINOACIDA. EL PRECURSOR DE RCNP Y SUS DERIVADOS SON NUEVOS Y TIENEN ACTIVIDADES NATRIURETICAS E HIPOTENSORAS.
ES91115393T 1990-09-11 1991-09-11 Adnc para un peptido natriuretico de tipo c de rata, y proteina precursora. Expired - Lifetime ES2104639T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP02241074A JP3026352B2 (ja) 1990-09-11 1990-09-11 ラットＣＮＰｃＤＮＡ及び前駆体蛋白

Publications (1)

Publication Number Publication Date
ES2104639T3 true ES2104639T3 (es) 1997-10-16

Family

ID=17068911

Family Applications (1)

Application Number Title Priority Date Filing Date
ES91115393T Expired - Lifetime ES2104639T3 (es) 1990-09-11 1991-09-11 Adnc para un peptido natriuretico de tipo c de rata, y proteina precursora.

Country Status (8)

Country Link
US (1) US5973134A (es)
EP (1) EP0475394B1 (es)
JP (1) JP3026352B2 (es)
AT (1) ATE154387T1 (es)
DE (1) DE69126487T2 (es)
DK (1) DK0475394T3 (es)
ES (1) ES2104639T3 (es)
GR (1) GR3024580T3 (es)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL142118A0 (en) * 2001-03-20 2002-03-10 Prochon Biotech Ltd Method and composition for treatment of skeletal dysplasias
JP4825667B2 (ja) 2004-03-31 2011-11-30 一和 中尾 関節炎症治療剤又は予防剤
KR20070007842A (ko) 2004-03-31 2007-01-16 카즈와 나카오 신장증가용 조성물
PL1759001T3 (pl) 2004-04-21 2011-09-30 Alexion Pharma Inc Koniugaty dostarczane do kości i sposób ich zastosowania do nakierowywania białek do kości
CA2823066A1 (en) 2010-12-27 2012-07-05 Alexion Pharma International Sarl Compositions comprising natriuretic peptides and methods of use thereof
US10052366B2 (en) 2012-05-21 2018-08-21 Alexion Pharmaceuticsl, Inc. Compositions comprising alkaline phosphatase and/or natriuretic peptide and methods of use thereof
US10822596B2 (en) 2014-07-11 2020-11-03 Alexion Pharmaceuticals, Inc. Compositions and methods for treating craniosynostosis
MX2017007392A (es) 2014-12-05 2019-01-24 Alexion Pharma Inc Tratamiento de convulsiones con fosfatasa alcalina recombinante.
US10603361B2 (en) 2015-01-28 2020-03-31 Alexion Pharmaceuticals, Inc. Methods of treating a subject with an alkaline phosphatase deficiency
CN108350440A (zh) 2015-08-17 2018-07-31 阿雷克森制药公司 碱性磷酸酯的制造
EP3355904A4 (en) 2015-09-28 2019-06-12 Alexion Pharmaceuticals, Inc. IDENTIFICATION OF EFFECTIVE DOSE SHEETS FOR TISSUE-SPECIFIC ALKALINE PHOSPHATASE ENZYMERSAT THERAPY OF HYPOPHOSPHATASIA
US11400140B2 (en) 2015-10-30 2022-08-02 Alexion Pharmaceuticals, Inc. Methods for treating craniosynostosis in a patient
EP3426286A4 (en) 2016-03-08 2019-12-04 Alexion Pharmaceuticals, Inc. METHODS OF TREATING HYPOPHOSPHATASE IN CHILDREN
WO2017173395A1 (en) 2016-04-01 2017-10-05 Alexion Pharmaceuticals, Inc. Methods for treating hypophosphatasia in adolescents and adults
CA3019726A1 (en) 2016-04-01 2017-10-05 Alexion Pharmaceuticals, Inc. Treating muscle weakness with alkaline phosphatases
EP3464573A4 (en) 2016-06-06 2020-02-19 Alexion Pharmaceuticals, Inc. IMPACT OF METAL ON THE PRODUCTION OF ALKALINE PHOSPHATASES
US11116821B2 (en) 2016-08-18 2021-09-14 Alexion Pharmaceuticals, Inc. Methods for treating tracheobronchomalacia
KR20190129058A (ko) 2017-03-31 2019-11-19 알렉시온 파마슈티칼스, 인코포레이티드 성인 및 청소년에서 저포스파타제증 (hpp)을 치료하는 방법
WO2019190752A1 (en) 2018-03-30 2019-10-03 Alexion Pharmaceuticals, Inc. Manufacturing of glycoproteins

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3026351B2 (ja) * 1990-07-13 2000-03-27 壽之 松尾 ブタｃｎｐ遺伝子及び前駆体蛋白

Also Published As

Publication number Publication date
EP0475394B1 (en) 1997-06-11
DE69126487T2 (de) 1997-11-27
EP0475394A3 (en) 1992-09-16
DE69126487D1 (de) 1997-07-17
JPH04121190A (ja) 1992-04-22
EP0475394A2 (en) 1992-03-18
JP3026352B2 (ja) 2000-03-27
DK0475394T3 (da) 1997-07-07
ATE154387T1 (de) 1997-06-15
US5973134A (en) 1999-10-26
GR3024580T3 (en) 1997-12-31

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